Rattus norvegicus

19 known processes

Map3k9

mitogen-activated protein kinase kinase kinase 9

(Aliases: RGD1562149)

Map3k9 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein complex biogenesis GO:0070271 263 0.257
synaptic transmission GO:0007268 235 0.234
cellular component biogenesis GO:0044085 368 0.219
protein complex assembly GO:0006461 263 0.217
cation transport GO:0006812 382 0.188
response to peptide GO:1901652 292 0.181
cellular response to oxygen containing compound GO:1901701 386 0.165
response to inorganic substance GO:0010035 377 0.158
cellular response to organic cyclic compound GO:0071407 202 0.153
protein complex subunit organization GO:0071822 302 0.146
response to glucocorticoid GO:0051384 223 0.142
regulation of neurogenesis GO:0050767 247 0.140
response to mineralocorticoid GO:0051385 49 0.140
positive regulation of transport GO:0051050 245 0.134
cellular component assembly GO:0022607 360 0.134
synaptic growth at neuromuscular junction GO:0051124 1 0.126
protein heterooligomerization GO:0051291 89 0.118
single organism biosynthetic process GO:0044711 342 0.109
reproductive process GO:0022414 372 0.106
regulation of vesicle mediated transport GO:0060627 81 0.105
cellular response to hormone stimulus GO:0032870 247 0.101
response to alkaloid GO:0043279 132 0.100
regulation of nervous system development GO:0051960 264 0.100
macromolecular complex subunit organization GO:0043933 339 0.095
response to toxic substance GO:0009636 133 0.095
response to corticosteroid GO:0031960 235 0.093
macromolecular complex assembly GO:0065003 273 0.091
multi organism reproductive process GO:0044703 262 0.087
positive regulation of secretion GO:0051047 140 0.083
cell cell signaling GO:0007267 335 0.082
neuron projection development GO:0031175 273 0.078
organophosphate metabolic process GO:0019637 370 0.077
response to ketone GO:1901654 182 0.077
regulation of cellular component organization GO:0051128 368 0.072
cell projection organization GO:0030030 302 0.071
vitamin transport GO:0051180 14 0.071
regulation of exocytosis GO:0017157 37 0.066
nucleic acid templated transcription GO:0097659 379 0.066
protein oligomerization GO:0051259 191 0.066
response to peptide hormone GO:0043434 278 0.065
response to extracellular stimulus GO:0009991 380 0.064
positive regulation of secretion by cell GO:1903532 128 0.064
inorganic cation transmembrane transport GO:0098662 202 0.063
regulation of ion transmembrane transporter activity GO:0032412 48 0.062
response to metal ion GO:0010038 253 0.057
secretion by cell GO:0032940 248 0.057
neuron differentiation GO:0030182 368 0.057
neuron development GO:0048666 286 0.055
ribonucleotide metabolic process GO:0009259 231 0.054
single organism behavior GO:0044708 130 0.053
phosphatidylinositol dephosphorylation GO:0046856 4 0.052
response to hexose GO:0009746 144 0.052
inorganic ion transmembrane transport GO:0098660 229 0.052
regulation of transcription dna templated GO:0006355 374 0.051
negative regulation of rna metabolic process GO:0051253 123 0.050
regulation of secretion GO:0051046 224 0.050
response to heat GO:0009408 60 0.050
intracellular signal transduction GO:0035556 314 0.049
regulation of molecular function GO:0065009 398 0.048
response to decreased oxygen levels GO:0036293 237 0.047
cation transmembrane transport GO:0098655 263 0.047
response to carbohydrate GO:0009743 183 0.047
response to estrogen GO:0043627 232 0.047
positive regulation of phosphate metabolic process GO:0045937 262 0.046
transcription dna templated GO:0006351 377 0.046
programmed cell death GO:0012501 392 0.045
organic anion transport GO:0015711 132 0.044
metal ion transport GO:0030001 289 0.043
response to cocaine GO:0042220 39 0.043
organelle organization GO:0006996 266 0.042
regulation of dendrite development GO:0050773 59 0.042
regulation of cellular localization GO:0060341 263 0.041
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.041
rhythmic process GO:0048511 156 0.041
cellular response to peptide GO:1901653 133 0.040
vesicle mediated transport GO:0016192 181 0.040
cellular homeostasis GO:0019725 252 0.040
cellular chemical homeostasis GO:0055082 247 0.040
regulation of rna biosynthetic process GO:2001141 381 0.039
regulation of hormone levels GO:0010817 187 0.039
response to nutrient levels GO:0031667 370 0.037
cellular calcium ion homeostasis GO:0006874 160 0.037
cellular response to endogenous stimulus GO:0071495 377 0.037
exocytosis GO:0006887 60 0.037
purine containing compound biosynthetic process GO:0072522 85 0.037
neuromuscular synaptic transmission GO:0007274 2 0.036
synapse organization GO:0050808 46 0.036
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.036
g protein coupled receptor signaling pathway GO:0007186 242 0.036
nucleobase containing small molecule metabolic process GO:0055086 316 0.035
secretion GO:0046903 307 0.035
carbohydrate derivative metabolic process GO:1901135 346 0.034
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.034
chemical homeostasis GO:0048878 292 0.034
regulation of cellular component movement GO:0051270 150 0.033
cellular response to glucocorticoid stimulus GO:0071385 68 0.032
regulation of phosphate metabolic process GO:0019220 349 0.032
negative regulation of cellular biosynthetic process GO:0031327 161 0.032
response to acid chemical GO:0001101 222 0.032
response to monosaccharide GO:0034284 159 0.032
cellular response to lipid GO:0071396 201 0.032
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.031
circadian rhythm GO:0007623 88 0.031
regulation of nucleic acid templated transcription GO:1903506 380 0.031
regulation of transferase activity GO:0051338 123 0.030
nitrogen compound transport GO:0071705 229 0.030
heart contraction GO:0060047 57 0.030
cellular potassium ion transport GO:0071804 72 0.030
response to hypoxia GO:0001666 231 0.030
positive regulation of cellular biosynthetic process GO:0031328 295 0.030
organelle localization GO:0051640 55 0.030
positive regulation of protein metabolic process GO:0051247 178 0.029
regulation of cell projection organization GO:0031344 175 0.029
negative regulation of cellular component organization GO:0051129 83 0.029
negative regulation of macromolecule metabolic process GO:0010605 260 0.029
cellular divalent inorganic cation homeostasis GO:0072503 162 0.029
steroid metabolic process GO:0008202 73 0.028
regulation of kinase activity GO:0043549 117 0.028
regulation of signal transduction GO:0009966 318 0.028
growth GO:0040007 165 0.028
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.028
reproduction GO:0000003 245 0.028
regulation of muscle system process GO:0090257 79 0.027
positive regulation of mapk cascade GO:0043410 92 0.027
calcium ion transmembrane transport GO:0070588 70 0.027
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.027
regulation of cellular protein metabolic process GO:0032268 267 0.027
regulation of secretion by cell GO:1903530 208 0.027
actin filament based process GO:0030029 86 0.027
hormone metabolic process GO:0042445 69 0.027
negative regulation of signaling GO:0023057 157 0.026
regulation of synaptic transmission GO:0050804 141 0.026
positive regulation of apoptotic process GO:0043065 154 0.026
regulation of growth GO:0040008 105 0.026
regulation of neuron projection development GO:0010975 161 0.026
response to ammonium ion GO:0060359 71 0.026
regulation of cell development GO:0060284 263 0.026
ion transmembrane transport GO:0034220 365 0.026
rna biosynthetic process GO:0032774 380 0.025
apoptotic process GO:0006915 381 0.025
calcium ion homeostasis GO:0055074 162 0.025
epithelium development GO:0060429 96 0.025
nucleoside phosphate biosynthetic process GO:1901293 102 0.025
positive regulation of cell death GO:0010942 184 0.025
response to oxidative stress GO:0006979 186 0.025
regulation of catalytic activity GO:0050790 304 0.025
single organism reproductive process GO:0044702 297 0.025
response to cytokine GO:0034097 215 0.024
purine nucleotide biosynthetic process GO:0006164 83 0.024
ribonucleotide biosynthetic process GO:0009260 85 0.024
positive regulation of catalytic activity GO:0043085 184 0.024
response to oxygen levels GO:0070482 265 0.024
regulation of ion transport GO:0043269 245 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
cellular ketone metabolic process GO:0042180 51 0.023
cation homeostasis GO:0055080 195 0.023
smooth muscle contraction GO:0006939 37 0.023
lipid metabolic process GO:0006629 283 0.023
divalent metal ion transport GO:0070838 132 0.023
locomotor rhythm GO:0045475 1 0.023
nucleoside phosphate metabolic process GO:0006753 283 0.023
transmembrane transport GO:0055085 412 0.023
regulation of membrane potential GO:0042391 110 0.023
response to insulin GO:0032868 133 0.023
response to retinoic acid GO:0032526 63 0.023
cellular response to organonitrogen compound GO:0071417 197 0.023
regulation of protein serine threonine kinase activity GO:0071900 64 0.023
c21 steroid hormone metabolic process GO:0008207 14 0.023
single organism organelle organization GO:1902589 180 0.022
positive regulation of cellular component organization GO:0051130 200 0.022
cellular response to peptide hormone stimulus GO:0071375 120 0.022
regulation of phosphorus metabolic process GO:0051174 349 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.021
homeostatic process GO:0042592 331 0.021
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.021
organic hydroxy compound transport GO:0015850 77 0.021
organophosphate biosynthetic process GO:0090407 143 0.021
urinary bladder smooth muscle contraction GO:0014832 4 0.021
behavior GO:0007610 205 0.021
regulation of protein modification process GO:0031399 194 0.020
negative regulation of response to stimulus GO:0048585 155 0.020
peptide hormone secretion GO:0030072 84 0.020
cellular metal ion homeostasis GO:0006875 172 0.020
asymmetric protein localization GO:0008105 2 0.020
erk1 and erk2 cascade GO:0070371 48 0.020
regulation of organelle organization GO:0033043 80 0.020
response to radiation GO:0009314 137 0.020
response to glucose GO:0009749 136 0.020
amino acid transport GO:0006865 70 0.020
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.020
positive regulation of molecular function GO:0044093 230 0.020
positive regulation of transcription dna templated GO:0045893 197 0.020
multicellular organism growth GO:0035264 1 0.019
cell adhesion GO:0007155 110 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
regulation of vascular smooth muscle contraction GO:0003056 3 0.019
cellular lipid metabolic process GO:0044255 208 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.019
digestive system development GO:0055123 41 0.019
gland development GO:0048732 155 0.019
regulation of protein kinase activity GO:0045859 105 0.019
negative regulation of cell communication GO:0010648 158 0.019
response to vitamin GO:0033273 131 0.018
organic acid transport GO:0015849 116 0.018
muscle system process GO:0003012 115 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
rna metabolic process GO:0016070 406 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
positive regulation of map kinase activity GO:0043406 46 0.018
formation of primary germ layer GO:0001704 1 0.018
sexual reproduction GO:0019953 148 0.018
positive regulation of muscle contraction GO:0045933 22 0.018
cell part morphogenesis GO:0032990 123 0.018
anion transport GO:0006820 178 0.018
regulation of cell differentiation GO:0045595 320 0.018
membrane organization GO:0061024 94 0.018
camp biosynthetic process GO:0006171 47 0.017
regulation of anatomical structure size GO:0090066 135 0.017
cellular response to nitrogen compound GO:1901699 210 0.017
negative regulation of phosphorus metabolic process GO:0010563 80 0.017
regulation of calcium ion transport GO:0051924 77 0.017
response to corticosterone GO:0051412 40 0.017
cyclic nucleotide metabolic process GO:0009187 80 0.017
cellular response to steroid hormone stimulus GO:0071383 93 0.017
memory GO:0007613 54 0.017
purine containing compound metabolic process GO:0072521 253 0.017
regulation of intracellular signal transduction GO:1902531 218 0.017
regulation of cellular component biogenesis GO:0044087 86 0.017
response to nutrient GO:0007584 248 0.017
regulation of lipid metabolic process GO:0019216 68 0.016
cardiac muscle cell contraction GO:0086003 10 0.016
response to osmotic stress GO:0006970 42 0.016
aging GO:0007568 241 0.016
antibiotic transport GO:0042891 2 0.016
circulatory system process GO:0003013 183 0.016
organophosphate catabolic process GO:0046434 148 0.016
negative regulation of cell death GO:0060548 229 0.016
regulation of map kinase activity GO:0043405 53 0.016
regulation of smooth muscle contraction GO:0006940 29 0.016
lipid biosynthetic process GO:0008610 128 0.016
steroid biosynthetic process GO:0006694 48 0.016
regulation of camp metabolic process GO:0030814 43 0.016
blood circulation GO:0008015 183 0.016
central nervous system development GO:0007417 311 0.016
intracellular transport GO:0046907 185 0.016
multicellular organismal reproductive process GO:0048609 233 0.016
cognition GO:0050890 92 0.016
phospholipid metabolic process GO:0006644 61 0.016
regulation of rna metabolic process GO:0051252 391 0.016
positive regulation of nervous system development GO:0051962 178 0.016
regulation of cell migration GO:0030334 128 0.015
synapse assembly GO:0007416 29 0.015
lipid modification GO:0030258 52 0.015
cellular response to acid chemical GO:0071229 75 0.015
metal ion homeostasis GO:0055065 186 0.015
regulation of locomotion GO:0040012 148 0.015
c21 steroid hormone biosynthetic process GO:0006700 10 0.015
gamete generation GO:0007276 124 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
response to ethanol GO:0045471 162 0.015
ribose phosphate biosynthetic process GO:0046390 87 0.015
positive regulation of signaling GO:0023056 270 0.015
regulation of purine nucleotide metabolic process GO:1900542 115 0.015
regulation of transmembrane transporter activity GO:0022898 49 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.015
regulation of camp biosynthetic process GO:0030817 38 0.015
cellular response to insulin stimulus GO:0032869 81 0.014
negative regulation of transport GO:0051051 136 0.014
olfactory learning GO:0008355 1 0.014
regulation of blood pressure GO:0008217 83 0.014
positive regulation of amine transport GO:0051954 26 0.014
dendrite morphogenesis GO:0048813 43 0.014
hormone secretion GO:0046879 115 0.014
chemosensory behavior GO:0007635 2 0.014
activation of protein kinase b activity GO:0032148 3 0.014
associative learning GO:0008306 19 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
female pregnancy GO:0007565 122 0.014
establishment of organelle localization GO:0051656 37 0.014
positive regulation of peptide secretion GO:0002793 52 0.014
regulation of cell motility GO:2000145 131 0.014
cell morphogenesis GO:0000902 142 0.014
response to electrical stimulus GO:0051602 56 0.014
divalent inorganic cation transport GO:0072511 134 0.014
neurotransmitter transport GO:0006836 42 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.013
cellular catabolic process GO:0044248 295 0.013
negative regulation of signal transduction GO:0009968 83 0.013
neuron death GO:0070997 127 0.013
mitotic spindle organization GO:0007052 2 0.013
ion homeostasis GO:0050801 212 0.013
regulation of synaptic plasticity GO:0048167 70 0.013
potassium ion transport GO:0006813 97 0.013
cyclic nucleotide biosynthetic process GO:0009190 63 0.013
organic acid metabolic process GO:0006082 292 0.013
brain development GO:0007420 247 0.013
protein homooligomerization GO:0051260 91 0.013
regulation of phosphorylation GO:0042325 248 0.013
camp metabolic process GO:0046058 63 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
regulation of multicellular organismal development GO:2000026 376 0.013
regulation of actin filament based process GO:0032970 42 0.013
potassium ion transmembrane transport GO:0071805 71 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
behavioral response to nicotine GO:0035095 2 0.013
cellular response to retinoic acid GO:0071300 27 0.013
transcription from rna polymerase ii promoter GO:0006366 252 0.013
cyclic purine nucleotide metabolic process GO:0052652 62 0.013
dna metabolic process GO:0006259 96 0.012
protein phosphorylation GO:0006468 345 0.012
positive regulation of growth GO:0045927 55 0.012
ras protein signal transduction GO:0007265 29 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.012
regulation of synapse organization GO:0050807 19 0.012
sequestering of metal ion GO:0051238 9 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
heart morphogenesis GO:0003007 3 0.012
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.012
positive regulation of cellular component biogenesis GO:0044089 55 0.012
urinary tract smooth muscle contraction GO:0014848 4 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
positive regulation of rna biosynthetic process GO:1902680 197 0.012
cellular response to ketone GO:1901655 51 0.012
acid secretion GO:0046717 48 0.012
dopamine secretion GO:0014046 15 0.012
anion transmembrane transport GO:0098656 77 0.012
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.012
response to progesterone GO:0032570 48 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
catecholamine transport GO:0051937 37 0.012
micturition GO:0060073 4 0.012
regulation of blood circulation GO:1903522 110 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
olfactory behavior GO:0042048 2 0.012
regulation of excitatory postsynaptic membrane potential GO:0060079 18 0.012
anatomical structure morphogenesis GO:0009653 298 0.012
transforming growth factor beta receptor signaling pathway GO:0007179 18 0.012
chromosome segregation GO:0007059 2 0.012
cell projection morphogenesis GO:0048858 123 0.011
regulation of metal ion transport GO:0010959 118 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
spindle organization GO:0007051 2 0.011
hormone transport GO:0009914 121 0.011
regulation of cell proliferation GO:0042127 359 0.011
regulation of system process GO:0044057 208 0.011
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 27 0.011
calcium ion transport GO:0006816 131 0.011
negative regulation of dopamine secretion GO:0033602 4 0.011
grooming behavior GO:0007625 4 0.011
positive regulation of cell growth GO:0030307 44 0.011
biological adhesion GO:0022610 110 0.011
positive regulation of protein kinase activity GO:0045860 73 0.011
regulation of dna metabolic process GO:0051052 60 0.011
endocytosis GO:0006897 84 0.011
regulation of neurotransmitter secretion GO:0046928 19 0.011
molting cycle GO:0042303 3 0.011
cellular response to external stimulus GO:0071496 118 0.011
response to purine containing compound GO:0014074 126 0.011
action potential GO:0001508 54 0.011
neurological system process GO:0050877 219 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
cell growth GO:0016049 104 0.011
negative regulation of cell development GO:0010721 82 0.010
nucleotide metabolic process GO:0009117 279 0.010
single organism intracellular transport GO:1902582 166 0.010
cellular macromolecular complex assembly GO:0034622 58 0.010
embryonic pattern specification GO:0009880 1 0.010
divalent inorganic cation homeostasis GO:0072507 165 0.010
positive regulation of synaptic vesicle transport GO:1902805 3 0.010
positive regulation of organelle organization GO:0010638 48 0.010
serotonin receptor signaling pathway GO:0007210 10 0.010
cellular cation homeostasis GO:0030003 180 0.010
synaptic transmission glycinergic GO:0060012 2 0.010
positive regulation of nucleic acid templated transcription GO:1903508 197 0.010
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.010
dendrite development GO:0016358 72 0.010
regulation of smooth muscle cell migration GO:0014910 36 0.010
cellular ion homeostasis GO:0006873 184 0.010
cytosolic calcium ion homeostasis GO:0051480 140 0.010

Map3k9 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.012
disease of metabolism DOID:0014667 0 0.010