Rattus norvegicus

87 known processes

Map3k7

mitogen activated protein kinase kinase kinase 7

(Aliases: Tak1)

Map3k7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna metabolic process GO:0016070 406 0.067
organelle organization GO:0006996 266 0.067
Human
cellular response to stress GO:0033554 269 0.066
Human Mouse Fly
protein phosphorylation GO:0006468 345 0.056
regulation of transcription dna templated GO:0006355 374 0.054
regulation of apoptotic process GO:0042981 335 0.052
Mouse
regulation of signal transduction GO:0009966 318 0.051
regulation of nervous system development GO:0051960 264 0.048
neuron differentiation GO:0030182 368 0.048
positive regulation of multicellular organismal process GO:0051240 387 0.045
Human
transcription dna templated GO:0006351 377 0.044
negative regulation of macromolecule metabolic process GO:0010605 260 0.043
positive regulation of phosphate metabolic process GO:0045937 262 0.042
cellular catabolic process GO:0044248 295 0.042
Fly
regulation of cell development GO:0060284 263 0.041
response to nutrient levels GO:0031667 370 0.040
intracellular signal transduction GO:0035556 314 0.040
positive regulation of cell development GO:0010720 176 0.040
neuron projection development GO:0031175 273 0.039
neuron development GO:0048666 286 0.038
regulation of neurogenesis GO:0050767 247 0.038
response to inorganic substance GO:0010035 377 0.038
cellular amino acid metabolic process GO:0006520 107 0.037
carboxylic acid metabolic process GO:0019752 289 0.035
regulation of phosphorus metabolic process GO:0051174 349 0.035
protein complex biogenesis GO:0070271 263 0.035
Mouse
macromolecule localization GO:0033036 252 0.035
Worm
cellular component biogenesis GO:0044085 368 0.034
Mouse
positive regulation of signaling GO:0023056 270 0.034
regulation of cellular component organization GO:0051128 368 0.033
Mouse
regulation of multicellular organismal development GO:2000026 376 0.033
response to extracellular stimulus GO:0009991 380 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.032
regulation of catalytic activity GO:0050790 304 0.032
regulation of cellular amine metabolic process GO:0033238 8 0.032
positive regulation of developmental process GO:0051094 283 0.032
positive regulation of nervous system development GO:0051962 178 0.031
regulation of phosphate metabolic process GO:0019220 349 0.030
regulation of neuron differentiation GO:0045664 208 0.030
macromolecular complex subunit organization GO:0043933 339 0.030
Human Mouse
cellular ketone metabolic process GO:0042180 51 0.030
positive regulation of neurogenesis GO:0050769 165 0.030
organic acid metabolic process GO:0006082 292 0.029
regulation of cell projection organization GO:0031344 175 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.028
Fly
central nervous system development GO:0007417 311 0.028
chromosome segregation GO:0007059 2 0.028
regulation of cellular protein metabolic process GO:0032268 267 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
cellular response to oxygen containing compound GO:1901701 386 0.027
Fly
carbohydrate derivative metabolic process GO:1901135 346 0.027
cell projection organization GO:0030030 302 0.027
regulation of protein metabolic process GO:0051246 289 0.027
cellular amine metabolic process GO:0044106 38 0.027
rna biosynthetic process GO:0032774 380 0.027
anatomical structure morphogenesis GO:0009653 298 0.027
Zebrafish Mouse Worm Fly
nucleic acid templated transcription GO:0097659 379 0.027
regulation of programmed cell death GO:0043067 341 0.025
Mouse
regulation of protein kinase activity GO:0045859 105 0.025
amine metabolic process GO:0009308 38 0.024
positive regulation of cellular amine metabolic process GO:0033240 3 0.024
cellular response to endogenous stimulus GO:0071495 377 0.024
Mouse
cytoplasmic transport GO:0016482 115 0.024
positive regulation of catalytic activity GO:0043085 184 0.024
regulation of intracellular signal transduction GO:1902531 218 0.024
intracellular transport GO:0046907 185 0.024
regulation of protein modification process GO:0031399 194 0.024
protein complex subunit organization GO:0071822 302 0.024
Mouse
positive regulation of molecular function GO:0044093 230 0.023
cell growth GO:0016049 104 0.023
proteolysis GO:0006508 175 0.023
positive regulation of cell communication GO:0010647 271 0.023
positive regulation of cellular component organization GO:0051130 200 0.023
organic substance catabolic process GO:1901575 316 0.022
positive regulation of neuron differentiation GO:0045666 126 0.022
regulation of cell differentiation GO:0045595 320 0.022
positive regulation of protein modification process GO:0031401 142 0.022
positive regulation of neuron projection development GO:0010976 99 0.022
response to metal ion GO:0010038 253 0.022
purine containing compound metabolic process GO:0072521 253 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
Fly
single organism intracellular transport GO:1902582 166 0.022
multicellular organismal reproductive process GO:0048609 233 0.021
regulation of neuron projection development GO:0010975 161 0.021
positive regulation of protein phosphorylation GO:0001934 135 0.021
macromolecular complex assembly GO:0065003 273 0.021
Mouse
negative regulation of metabolic process GO:0009892 331 0.020
Mouse
reproductive process GO:0022414 372 0.020
positive regulation of protein metabolic process GO:0051247 178 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.020
cellular response to organic cyclic compound GO:0071407 202 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
regulation of rna biosynthetic process GO:2001141 381 0.020
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
negative regulation of rna biosynthetic process GO:1902679 118 0.020
negative regulation of cell differentiation GO:0045596 99 0.020
positive regulation of nucleic acid templated transcription GO:1903508 197 0.020
homeostatic process GO:0042592 331 0.019
programmed cell death GO:0012501 392 0.019
Mouse Fly
positive regulation of cell differentiation GO:0045597 217 0.019
cellular macromolecule localization GO:0070727 122 0.019
positive regulation of cell proliferation GO:0008284 249 0.019
regulation of nucleic acid templated transcription GO:1903506 380 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
single organism catabolic process GO:0044712 283 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
cellular response to growth factor stimulus GO:0071363 162 0.019
Mouse
negative regulation of cellular metabolic process GO:0031324 281 0.019
Mouse
regulation of cellular ketone metabolic process GO:0010565 27 0.019
organophosphate metabolic process GO:0019637 370 0.018
protein localization GO:0008104 191 0.018
Worm
regulation of cell proliferation GO:0042127 359 0.018
negative regulation of multicellular organismal process GO:0051241 203 0.018
single organism reproductive process GO:0044702 297 0.018
negative regulation of cell death GO:0060548 229 0.018
Mouse
growth GO:0040007 165 0.018
response to growth factor GO:0070848 189 0.018
Mouse
protein oligomerization GO:0051259 191 0.018
reproduction GO:0000003 245 0.018
response to radiation GO:0009314 137 0.018
positive regulation of cell projection organization GO:0031346 111 0.017
cell cycle GO:0007049 101 0.017
negative regulation of cell communication GO:0010648 158 0.017
Mouse
cellular component movement GO:0006928 248 0.017
cell migration GO:0016477 197 0.017
regulation of molecular function GO:0065009 398 0.017
dna metabolic process GO:0006259 96 0.017
cell morphogenesis involved in differentiation GO:0000904 119 0.017
positive regulation of signal transduction GO:0009967 175 0.017
enzyme linked receptor protein signaling pathway GO:0007167 116 0.016
Mouse
nucleoside phosphate metabolic process GO:0006753 283 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
apoptotic process GO:0006915 381 0.016
Mouse Fly
negative regulation of developmental process GO:0051093 125 0.016
response to ethanol GO:0045471 162 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
Mouse
positive regulation of response to stimulus GO:0048584 285 0.016
regulation of growth GO:0040008 105 0.016
locomotion GO:0040011 237 0.016
ras protein signal transduction GO:0007265 29 0.016
metaphase anaphase transition of mitotic cell cycle GO:0007091 1 0.016
regulation of mapk cascade GO:0043408 116 0.016
metal ion transport GO:0030001 289 0.016
purine nucleotide metabolic process GO:0006163 229 0.015
negative regulation of apoptotic process GO:0043066 181 0.015
Mouse
cellular response to nitrogen compound GO:1901699 210 0.015
negative regulation of molecular function GO:0044092 133 0.015
oxoacid metabolic process GO:0043436 290 0.015
protein complex assembly GO:0006461 263 0.015
Mouse
chemical homeostasis GO:0048878 292 0.015
gastrulation GO:0007369 2 0.015
Worm
cell motility GO:0048870 202 0.015
multi organism reproductive process GO:0044703 262 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
reproductive structure development GO:0048608 128 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
catabolic process GO:0009056 351 0.015
Fly
cell cell signaling GO:0007267 335 0.015
response to biotic stimulus GO:0009607 226 0.015
Fly
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
response to peptide hormone GO:0043434 278 0.014
cellular ion homeostasis GO:0006873 184 0.014
b cell differentiation GO:0030183 2 0.014
regulation of phosphorylation GO:0042325 248 0.014
single organism organelle organization GO:1902589 180 0.014
Human
positive regulation of biosynthetic process GO:0009891 319 0.014
Fly
organic cyclic compound catabolic process GO:1901361 175 0.014
negative regulation of signaling GO:0023057 157 0.014
Mouse
response to other organism GO:0051707 220 0.014
Fly
cytoskeleton dependent cytokinesis GO:0061640 2 0.014
defense response GO:0006952 194 0.014
Worm Fly
aging GO:0007568 241 0.014
negative regulation of cell cycle phase transition GO:1901988 4 0.014
negative regulation of cellular component organization GO:0051129 83 0.014
Mouse
response to oxygen levels GO:0070482 265 0.014
ribonucleoside triphosphate catabolic process GO:0009203 122 0.014
negative regulation of programmed cell death GO:0043069 183 0.013
Mouse
response to monosaccharide GO:0034284 159 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
heterocycle catabolic process GO:0046700 167 0.013
tissue development GO:0009888 252 0.013
Mouse Worm Fly
response to lipopolysaccharide GO:0032496 191 0.013
Fly
positive regulation of transcription dna templated GO:0045893 197 0.013
muscle system process GO:0003012 115 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
response to acid chemical GO:0001101 222 0.013
response to wounding GO:0009611 254 0.013
axis specification GO:0009798 4 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
nucleotide catabolic process GO:0009166 139 0.013
transcription from rna polymerase ii promoter GO:0006366 252 0.013
cell cycle checkpoint GO:0000075 2 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
regulation of kinase activity GO:0043549 117 0.012
immune system process GO:0002376 204 0.012
Human Fly
nucleotide metabolic process GO:0009117 279 0.012
carbohydrate metabolic process GO:0005975 130 0.012
regulation of rna metabolic process GO:0051252 391 0.012
regulation of response to stress GO:0080134 126 0.012
Human Mouse Fly
multicellular organism reproduction GO:0032504 233 0.012
response to carbohydrate GO:0009743 183 0.012
regulation of cellular localization GO:0060341 263 0.012
negative regulation of gene expression GO:0010629 199 0.012
monovalent inorganic cation transport GO:0015672 172 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
cell morphogenesis GO:0000902 142 0.012
regulation of cell growth GO:0001558 85 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
chromosome organization GO:0051276 36 0.012
Human
regulation of transferase activity GO:0051338 123 0.012
cation transport GO:0006812 382 0.012
single organism cellular localization GO:1902580 102 0.012
anion transport GO:0006820 178 0.012
protein targeting GO:0006605 61 0.012
response to estradiol GO:0032355 164 0.012
immune response GO:0006955 104 0.012
Human Fly
cellular nitrogen compound catabolic process GO:0044270 163 0.012
response to peptide GO:1901652 292 0.012
regulation of organelle organization GO:0033043 80 0.011
cell communication involved in cardiac conduction GO:0086065 2 0.011
cellular component assembly GO:0022607 360 0.011
Mouse
positive regulation of transport GO:0051050 245 0.011
ion homeostasis GO:0050801 212 0.011
nucleoside monophosphate metabolic process GO:0009123 93 0.011
positive regulation of transferase activity GO:0051347 81 0.011
aromatic compound catabolic process GO:0019439 168 0.011
metaphase anaphase transition of cell cycle GO:0044784 1 0.011
positive regulation of gene expression GO:0010628 244 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
multicellular organism growth GO:0035264 1 0.011
cellular response to lipid GO:0071396 201 0.011
Fly
regulation of cell migration GO:0030334 128 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
behavior GO:0007610 205 0.011
positive regulation of protein kinase activity GO:0045860 73 0.011
response to decreased oxygen levels GO:0036293 237 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
brain development GO:0007420 247 0.011
response to external biotic stimulus GO:0043207 221 0.011
Fly
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
single organism biosynthetic process GO:0044711 342 0.011
cellular protein localization GO:0034613 122 0.011
sister chromatid segregation GO:0000819 1 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.010
nitrogen compound transport GO:0071705 229 0.010
intracellular protein transport GO:0006886 79 0.010
ribonucleoside catabolic process GO:0042454 126 0.010
organonitrogen compound biosynthetic process GO:1901566 167 0.010
Fly
mitotic sister chromatid separation GO:0051306 1 0.010
positive regulation of transcription factor import into nucleus GO:0042993 4 0.010
cardiac conduction GO:0061337 2 0.010
response to nutrient GO:0007584 248 0.010
negative regulation of transcription dna templated GO:0045892 116 0.010
response to estrogen GO:0043627 232 0.010
cellular homeostasis GO:0019725 252 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
regulation of system process GO:0044057 208 0.010
cellular response to external stimulus GO:0071496 118 0.010
regulation of cellular component biogenesis GO:0044087 86 0.010
Mouse
chromosome separation GO:0051304 1 0.010
regulation of sister chromatid segregation GO:0033045 1 0.010
head development GO:0060322 247 0.010
regeneration GO:0031099 163 0.010

Map3k7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.011
nervous system disease DOID:863 0 0.011