Rattus norvegicus

0 known processes

Rfx2

regulatory factor X, 2 (influences HLA class II expression)

Rfx2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleic acid templated transcription GO:0097659 379 0.109
transcription dna templated GO:0006351 377 0.103
intracellular signal transduction GO:0035556 314 0.083
protein phosphorylation GO:0006468 345 0.081
positive regulation of cellular biosynthetic process GO:0031328 295 0.070
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.069
positive regulation of signaling GO:0023056 270 0.066
regulation of phosphorus metabolic process GO:0051174 349 0.062
positive regulation of catalytic activity GO:0043085 184 0.062
response to metal ion GO:0010038 253 0.059
response to inorganic substance GO:0010035 377 0.058
positive regulation of phosphorus metabolic process GO:0010562 262 0.055
single organism catabolic process GO:0044712 283 0.055
regulation of catalytic activity GO:0050790 304 0.053
secretion GO:0046903 307 0.052
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.052
negative regulation of transport GO:0051051 136 0.052
regulation of molecular function GO:0065009 398 0.049
positive regulation of response to stimulus GO:0048584 285 0.049
regulation of protein phosphorylation GO:0001932 183 0.048
positive regulation of signal transduction GO:0009967 175 0.048
positive regulation of gene expression GO:0010628 244 0.046
rna metabolic process GO:0016070 406 0.046
positive regulation of cell communication GO:0010647 271 0.045
oxoacid metabolic process GO:0043436 290 0.044
anatomical structure morphogenesis GO:0009653 298 0.044
tissue development GO:0009888 252 0.043
nucleoside phosphate metabolic process GO:0006753 283 0.043
purine ribonucleoside metabolic process GO:0046128 168 0.043
rna biosynthetic process GO:0032774 380 0.043
regulation of nucleic acid templated transcription GO:1903506 380 0.042
regulation of cell differentiation GO:0045595 320 0.041
purine ribonucleotide catabolic process GO:0009154 136 0.041
regulation of rna biosynthetic process GO:2001141 381 0.041
response to extracellular stimulus GO:0009991 380 0.040
regulation of protein metabolic process GO:0051246 289 0.039
cell cell signaling GO:0007267 335 0.039
positive regulation of phosphate metabolic process GO:0045937 262 0.038
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.038
regulation of intracellular signal transduction GO:1902531 218 0.038
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.038
positive regulation of cell proliferation GO:0008284 249 0.037
regulation of programmed cell death GO:0043067 341 0.037
positive regulation of molecular function GO:0044093 230 0.037
purine containing compound metabolic process GO:0072521 253 0.037
regulation of rna metabolic process GO:0051252 391 0.037
reproductive process GO:0022414 372 0.036
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.036
response to nutrient GO:0007584 248 0.036
small gtpase mediated signal transduction GO:0007264 36 0.036
regulation of phosphorylation GO:0042325 248 0.035
ribose phosphate metabolic process GO:0019693 235 0.035
response to acid chemical GO:0001101 222 0.035
regulation of phosphate metabolic process GO:0019220 349 0.035
cellular amine metabolic process GO:0044106 38 0.035
regulation of cell development GO:0060284 263 0.034
positive regulation of cell differentiation GO:0045597 217 0.034
vascular process in circulatory system GO:0003018 96 0.034
regulation of cellular protein metabolic process GO:0032268 267 0.033
purine nucleotide catabolic process GO:0006195 136 0.033
ras protein signal transduction GO:0007265 29 0.033
carbohydrate derivative metabolic process GO:1901135 346 0.033
organic acid metabolic process GO:0006082 292 0.033
carboxylic acid metabolic process GO:0019752 289 0.032
heterocycle catabolic process GO:0046700 167 0.032
nucleoside triphosphate catabolic process GO:0009143 123 0.032
positive regulation of hydrolase activity GO:0051345 86 0.031
neurological system process GO:0050877 219 0.031
aromatic compound catabolic process GO:0019439 168 0.031
regulation of cellular localization GO:0060341 263 0.031
regulation of hormone levels GO:0010817 187 0.030
cellular amino acid metabolic process GO:0006520 107 0.030
response to nutrient levels GO:0031667 370 0.030
nucleotide metabolic process GO:0009117 279 0.030
cellular nitrogen compound catabolic process GO:0044270 163 0.030
neuron projection development GO:0031175 273 0.030
nucleoside triphosphate metabolic process GO:0009141 144 0.030
aging GO:0007568 241 0.030
positive regulation of biosynthetic process GO:0009891 319 0.030
regulation of hydrolase activity GO:0051336 143 0.030
regulation of signal transduction GO:0009966 318 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
regulation of apoptotic process GO:0042981 335 0.029
multi organism reproductive process GO:0044703 262 0.029
positive regulation of programmed cell death GO:0043068 157 0.029
multicellular organism reproduction GO:0032504 233 0.029
positive regulation of protein modification process GO:0031401 142 0.029
regulation of transcription dna templated GO:0006355 374 0.029
organophosphate metabolic process GO:0019637 370 0.029
nucleoside phosphate catabolic process GO:1901292 140 0.028
cellular response to oxygen containing compound GO:1901701 386 0.028
blood circulation GO:0008015 183 0.028
transcription from rna polymerase ii promoter GO:0006366 252 0.028
cellular component movement GO:0006928 248 0.028
nucleotide catabolic process GO:0009166 139 0.028
muscle system process GO:0003012 115 0.028
multicellular organismal reproductive process GO:0048609 233 0.028
single organism biosynthetic process GO:0044711 342 0.028
carbohydrate derivative catabolic process GO:1901136 147 0.027
regulation of neurogenesis GO:0050767 247 0.027
positive regulation of protein phosphorylation GO:0001934 135 0.027
positive regulation of cell death GO:0010942 184 0.027
organic cyclic compound catabolic process GO:1901361 175 0.027
apoptotic process GO:0006915 381 0.027
cell projection morphogenesis GO:0048858 123 0.027
tube development GO:0035295 89 0.027
positive regulation of rna metabolic process GO:0051254 203 0.027
non canonical wnt signaling pathway GO:0035567 3 0.027
nucleoside metabolic process GO:0009116 179 0.027
regulation of neuron differentiation GO:0045664 208 0.027
negative regulation of metabolic process GO:0009892 331 0.027
cardiac muscle contraction GO:0060048 27 0.026
cell part morphogenesis GO:0032990 123 0.026
neuron differentiation GO:0030182 368 0.026
amine metabolic process GO:0009308 38 0.026
ribonucleoside metabolic process GO:0009119 174 0.026
nucleobase containing compound catabolic process GO:0034655 152 0.026
organonitrogen compound catabolic process GO:1901565 179 0.026
purine containing compound catabolic process GO:0072523 138 0.026
organophosphate catabolic process GO:0046434 148 0.026
purine ribonucleotide metabolic process GO:0009150 227 0.026
rho protein signal transduction GO:0007266 11 0.026
cellular response to organonitrogen compound GO:0071417 197 0.025
ribonucleotide metabolic process GO:0009259 231 0.025
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
regulation of cell proliferation GO:0042127 359 0.025
positive regulation of cellular protein metabolic process GO:0032270 167 0.025
negative regulation of gene expression GO:0010629 199 0.025
cellular ketone metabolic process GO:0042180 51 0.025
regulation of protein modification process GO:0031399 194 0.024
purine ribonucleoside catabolic process GO:0046130 124 0.024
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.024
neuron projection morphogenesis GO:0048812 122 0.024
purine nucleoside catabolic process GO:0006152 124 0.024
glycosyl compound catabolic process GO:1901658 126 0.024
purine nucleotide metabolic process GO:0006163 229 0.024
positive regulation of apoptotic process GO:0043065 154 0.023
response to wounding GO:0009611 254 0.023
regulation of neuron projection development GO:0010975 161 0.023
glycosyl compound metabolic process GO:1901657 182 0.023
negative regulation of cellular metabolic process GO:0031324 281 0.023
positive regulation of phosphorylation GO:0042327 177 0.023
purine nucleoside triphosphate metabolic process GO:0009144 141 0.023
cellular homeostasis GO:0019725 252 0.023
negative regulation of rna biosynthetic process GO:1902679 118 0.023
ribonucleoside triphosphate metabolic process GO:0009199 141 0.023
cation transport GO:0006812 382 0.023
positive regulation of nucleic acid templated transcription GO:1903508 197 0.023
positive regulation of protein kinase activity GO:0045860 73 0.023
cell morphogenesis GO:0000902 142 0.023
regulation of multicellular organismal development GO:2000026 376 0.022
positive regulation of transcription dna templated GO:0045893 197 0.022
regulation of nervous system development GO:0051960 264 0.022
ribonucleotide catabolic process GO:0009261 136 0.022
ribonucleoside catabolic process GO:0042454 126 0.022
positive regulation of nucleoside metabolic process GO:0045979 55 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.022
regulation of protein kinase activity GO:0045859 105 0.022
cellular chemical homeostasis GO:0055082 247 0.022
nucleoside catabolic process GO:0009164 126 0.022
chemical homeostasis GO:0048878 292 0.022
positive regulation of multicellular organismal process GO:0051240 387 0.022
purine nucleoside triphosphate catabolic process GO:0009146 122 0.022
cellular catabolic process GO:0044248 295 0.022
cellular response to nitrogen compound GO:1901699 210 0.021
reproduction GO:0000003 245 0.021
organophosphate biosynthetic process GO:0090407 143 0.021
purine nucleoside metabolic process GO:0042278 169 0.021
regulation of tube size GO:0035150 89 0.021
single organism reproductive process GO:0044702 297 0.021
positive regulation of developmental process GO:0051094 283 0.021
positive regulation of protein metabolic process GO:0051247 178 0.020
gamete generation GO:0007276 124 0.020
neuron development GO:0048666 286 0.020
regulation of membrane potential GO:0042391 110 0.020
cell morphogenesis involved in differentiation GO:0000904 119 0.020
chemotaxis GO:0006935 66 0.020
cell projection organization GO:0030030 302 0.020
regulation of system process GO:0044057 208 0.020
catabolic process GO:0009056 351 0.020
liver development GO:0001889 90 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.019
response to peptide GO:1901652 292 0.019
locomotion GO:0040011 237 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
response to peptide hormone GO:0043434 278 0.019
positive regulation of transport GO:0051050 245 0.019
regulation of kinase activity GO:0043549 117 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
anterior posterior pattern specification GO:0009952 1 0.019
positive regulation of intracellular signal transduction GO:1902533 138 0.019
regulation of cellular amine metabolic process GO:0033238 8 0.019
cellular lipid metabolic process GO:0044255 208 0.019
regulation of cellular component organization GO:0051128 368 0.018
anion transport GO:0006820 178 0.018
positive regulation of nucleotide metabolic process GO:0045981 91 0.018
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.018
circulatory system process GO:0003013 183 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.018
regulation of nucleoside metabolic process GO:0009118 66 0.018
muscle structure development GO:0061061 87 0.018
regulation of muscle system process GO:0090257 79 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
ribonucleoside triphosphate catabolic process GO:0009203 122 0.018
regulation of nucleotide metabolic process GO:0006140 117 0.018
positive regulation of cell development GO:0010720 176 0.017
respiratory system development GO:0060541 45 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
organelle organization GO:0006996 266 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.017
negative regulation of molecular function GO:0044092 133 0.017
negative regulation of cell death GO:0060548 229 0.017
organic substance catabolic process GO:1901575 316 0.017
epithelial cell differentiation GO:0030855 71 0.017
brain development GO:0007420 247 0.016
programmed cell death GO:0012501 392 0.016
cellular component biogenesis GO:0044085 368 0.016
mapk cascade GO:0000165 140 0.016
epithelium development GO:0060429 96 0.016
heart process GO:0003015 57 0.016
sexual reproduction GO:0019953 148 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
regulation of purine nucleotide metabolic process GO:1900542 115 0.016
regulation of cellular catabolic process GO:0031329 101 0.016
response to carbohydrate GO:0009743 183 0.016
axonogenesis GO:0007409 71 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
bmp signaling pathway GO:0030509 4 0.016
calcium ion homeostasis GO:0055074 162 0.016
regulation of mapk cascade GO:0043408 116 0.016
regulation of purine nucleotide catabolic process GO:0033121 65 0.015
response to biotic stimulus GO:0009607 226 0.015
response to oxygen levels GO:0070482 265 0.015
positive regulation of nervous system development GO:0051962 178 0.015
regulation of nucleotide catabolic process GO:0030811 65 0.015
regulation of cell projection organization GO:0031344 175 0.015
regulation of ion transport GO:0043269 245 0.015
peptidyl amino acid modification GO:0018193 126 0.015
limb morphogenesis GO:0035108 4 0.015
establishment of tissue polarity GO:0007164 2 0.015
regulation of anatomical structure size GO:0090066 135 0.015
muscle contraction GO:0006936 88 0.015
response to bacterium GO:0009617 200 0.015
regulation of blood circulation GO:1903522 110 0.015
embryonic appendage morphogenesis GO:0035113 4 0.015
positive regulation of nucleotide catabolic process GO:0030813 53 0.015
forebrain development GO:0030900 98 0.015
cellular component assembly GO:0022607 360 0.015
spermatogenesis GO:0007283 99 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
carbohydrate derivative biosynthetic process GO:1901137 124 0.015
sensory perception GO:0007600 101 0.015
neural crest cell differentiation GO:0014033 2 0.015
macromolecular complex subunit organization GO:0043933 339 0.015
defense response GO:0006952 194 0.014
protein complex assembly GO:0006461 263 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.014
homeostatic process GO:0042592 331 0.014
striated muscle contraction GO:0006941 44 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
localization of cell GO:0051674 202 0.014
multicellular organism growth GO:0035264 1 0.014
single organism organelle organization GO:1902589 180 0.014
guanosine containing compound metabolic process GO:1901068 74 0.014
positive regulation of transferase activity GO:0051347 81 0.014
metal ion transport GO:0030001 289 0.014
axon development GO:0061564 96 0.014
ion homeostasis GO:0050801 212 0.014
oxidation reduction process GO:0055114 304 0.014
ion transmembrane transport GO:0034220 365 0.014
cyclic nucleotide metabolic process GO:0009187 80 0.014
cell migration GO:0016477 197 0.014
lipid biosynthetic process GO:0008610 128 0.014
response to estradiol GO:0032355 164 0.014
male gamete generation GO:0048232 99 0.014
regulation of secretion GO:0051046 224 0.014
cell adhesion GO:0007155 110 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
single organism carbohydrate metabolic process GO:0044723 118 0.013
macromolecular complex assembly GO:0065003 273 0.013
lipid storage GO:0019915 1 0.013
peptidyl tyrosine phosphorylation GO:0018108 72 0.013
regulation of transferase activity GO:0051338 123 0.013
regulation of synaptic transmission GO:0050804 141 0.013
negative regulation of developmental process GO:0051093 125 0.013
negative regulation of cell communication GO:0010648 158 0.013
response to corticosteroid GO:0031960 235 0.013
behavior GO:0007610 205 0.013
calcium ion transport GO:0006816 131 0.013
positive regulation of kinase activity GO:0033674 77 0.013
circulatory system development GO:0072359 134 0.013
hepaticobiliary system development GO:0061008 90 0.013
single organism intracellular transport GO:1902582 166 0.013
cellular response to peptide GO:1901653 133 0.013
cell growth GO:0016049 104 0.013
cation transmembrane transport GO:0098655 263 0.013
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
regulation of establishment of planar polarity GO:0090175 2 0.013
intracellular transport GO:0046907 185 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
cardiovascular system development GO:0072358 134 0.013
regulation of homotypic cell cell adhesion GO:0034110 4 0.013
response to ethanol GO:0045471 162 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
regulation of blood vessel size GO:0050880 89 0.013
response to estrogen GO:0043627 232 0.013
signal release GO:0023061 145 0.012
growth GO:0040007 165 0.012
purine nucleoside monophosphate metabolic process GO:0009126 84 0.012
protein complex biogenesis GO:0070271 263 0.012
regulation of protein serine threonine kinase activity GO:0071900 64 0.012
cytoskeleton organization GO:0007010 111 0.012
vasodilation GO:0042311 44 0.012
carbohydrate homeostasis GO:0033500 75 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.012
learning or memory GO:0007611 90 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.012
gtp metabolic process GO:0046039 72 0.012
cation homeostasis GO:0055080 195 0.012
organ morphogenesis GO:0009887 75 0.012
multi multicellular organism process GO:0044706 138 0.012
protein complex subunit organization GO:0071822 302 0.012
urinary bladder smooth muscle contraction GO:0014832 4 0.012
second messenger mediated signaling GO:0019932 51 0.012
cognition GO:0050890 92 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
nucleoside monophosphate catabolic process GO:0009125 56 0.011
heart development GO:0007507 72 0.011
mechanoreceptor differentiation GO:0042490 2 0.011
response to other organism GO:0051707 220 0.011
gastrulation GO:0007369 2 0.011
negative regulation of nervous system development GO:0051961 79 0.011
regulation of secretion by cell GO:1903530 208 0.011
small molecule biosynthetic process GO:0044283 124 0.011
multicellular organismal signaling GO:0035637 44 0.011
regulation of ion transmembrane transport GO:0034765 121 0.011
membrane hyperpolarization GO:0060081 11 0.011
response to calcium ion GO:0051592 59 0.011
ribonucleoside monophosphate metabolic process GO:0009161 88 0.011
divalent metal ion transport GO:0070838 132 0.011
female pregnancy GO:0007565 122 0.011
response to hexose GO:0009746 144 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
lipid metabolic process GO:0006629 283 0.011
heart morphogenesis GO:0003007 3 0.011
cellular ion homeostasis GO:0006873 184 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
cellular response to lipid GO:0071396 201 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
response to cytokine GO:0034097 215 0.011
negative regulation of rna metabolic process GO:0051253 123 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
organic acid transport GO:0015849 116 0.011
rhythmic process GO:0048511 156 0.011
guanosine containing compound catabolic process GO:1901069 71 0.011
morphogenesis of a polarized epithelium GO:0001738 1 0.011
maintenance of location GO:0051235 17 0.011
glucose homeostasis GO:0042593 75 0.011
carbohydrate metabolic process GO:0005975 130 0.011
organic anion transport GO:0015711 132 0.011
nucleoside monophosphate metabolic process GO:0009123 93 0.011
metal ion homeostasis GO:0055065 186 0.011
urinary tract smooth muscle contraction GO:0014848 4 0.011
atp metabolic process GO:0046034 72 0.011
gtp catabolic process GO:0006184 71 0.011
hematopoietic progenitor cell differentiation GO:0002244 2 0.011
head development GO:0060322 247 0.011
synaptic transmission GO:0007268 235 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
positive regulation of mapk cascade GO:0043410 92 0.010
macromolecule localization GO:0033036 252 0.010
telencephalon development GO:0021537 62 0.010
regulation of transporter activity GO:0032409 50 0.010
hormone secretion GO:0046879 115 0.010
positive regulation of ion transport GO:0043270 94 0.010
negative regulation of programmed cell death GO:0043069 183 0.010
cellular response to endogenous stimulus GO:0071495 377 0.010
enzyme linked receptor protein signaling pathway GO:0007167 116 0.010
central nervous system development GO:0007417 311 0.010
embryonic limb morphogenesis GO:0030326 4 0.010
response to lipopolysaccharide GO:0032496 191 0.010

Rfx2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.030
sensory system disease DOID:0050155 0 0.018
eye and adnexa disease DOID:1492 0 0.018
musculoskeletal system disease DOID:17 0 0.017
myopathy DOID:423 0 0.011
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011