Rattus norvegicus

0 known processes

Pdzrn3

PDZ domain containing RING finger 3

Pdzrn3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
locomotion GO:0040011 237 0.164
transcription dna templated GO:0006351 377 0.108
regulation of rna biosynthetic process GO:2001141 381 0.080
intracellular signal transduction GO:0035556 314 0.080
neuron development GO:0048666 286 0.073
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.073
regulation of nucleic acid templated transcription GO:1903506 380 0.069
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.066
rna metabolic process GO:0016070 406 0.063
anatomical structure morphogenesis GO:0009653 298 0.061
neuron differentiation GO:0030182 368 0.060
nucleic acid templated transcription GO:0097659 379 0.060
cell projection organization GO:0030030 302 0.059
cellular component movement GO:0006928 248 0.058
cell projection morphogenesis GO:0048858 123 0.052
positive regulation of phosphorus metabolic process GO:0010562 262 0.049
neuron projection development GO:0031175 273 0.048
central nervous system development GO:0007417 311 0.047
positive regulation of cellular biosynthetic process GO:0031328 295 0.046
regulation of transcription dna templated GO:0006355 374 0.045
positive regulation of intracellular signal transduction GO:1902533 138 0.045
regulation of phosphorus metabolic process GO:0051174 349 0.044
cell part morphogenesis GO:0032990 123 0.044
transcription from rna polymerase ii promoter GO:0006366 252 0.043
regulation of intracellular signal transduction GO:1902531 218 0.042
positive regulation of cell communication GO:0010647 271 0.042
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.041
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.041
apoptotic process GO:0006915 381 0.040
reproductive process GO:0022414 372 0.040
protein phosphorylation GO:0006468 345 0.040
cardiovascular system development GO:0072358 134 0.038
regulation of neurogenesis GO:0050767 247 0.038
positive regulation of molecular function GO:0044093 230 0.038
regulation of signal transduction GO:0009966 318 0.037
cellular response to oxygen containing compound GO:1901701 386 0.037
regulation of phosphorylation GO:0042325 248 0.037
regulation of cellular component organization GO:0051128 368 0.037
positive regulation of biosynthetic process GO:0009891 319 0.036
taxis GO:0042330 67 0.036
regulation of cell projection organization GO:0031344 175 0.035
regulation of nervous system development GO:0051960 264 0.034
rna biosynthetic process GO:0032774 380 0.034
negative regulation of metabolic process GO:0009892 331 0.033
circulatory system development GO:0072359 134 0.033
cell morphogenesis GO:0000902 142 0.032
reproduction GO:0000003 245 0.032
axonogenesis GO:0007409 71 0.032
regulation of cellular amino acid metabolic process GO:0006521 2 0.032
cellular ketone metabolic process GO:0042180 51 0.032
organophosphate metabolic process GO:0019637 370 0.032
regulation of cellular amine metabolic process GO:0033238 8 0.032
regulation of programmed cell death GO:0043067 341 0.031
secretion GO:0046903 307 0.030
regulation of multicellular organismal development GO:2000026 376 0.030
multicellular organism reproduction GO:0032504 233 0.030
establishment of protein localization GO:0045184 141 0.030
regulation of phosphate metabolic process GO:0019220 349 0.029
regulation of neuron death GO:1901214 115 0.029
regulation of catalytic activity GO:0050790 304 0.029
positive regulation of neurogenesis GO:0050769 165 0.029
carboxylic acid metabolic process GO:0019752 289 0.029
neuron apoptotic process GO:0051402 88 0.029
blood circulation GO:0008015 183 0.029
secretion by cell GO:0032940 248 0.028
positive regulation of phosphate metabolic process GO:0045937 262 0.028
positive regulation of response to stimulus GO:0048584 285 0.028
circulatory system process GO:0003013 183 0.028
oxoacid metabolic process GO:0043436 290 0.028
positive regulation of catalytic activity GO:0043085 184 0.028
regulation of protein modification process GO:0031399 194 0.028
positive regulation of cellular component organization GO:0051130 200 0.028
negative regulation of cellular metabolic process GO:0031324 281 0.027
multi organism reproductive process GO:0044703 262 0.027
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.027
chemotaxis GO:0006935 66 0.027
regulation of transferase activity GO:0051338 123 0.027
tissue development GO:0009888 252 0.027
positive regulation of nucleic acid templated transcription GO:1903508 197 0.026
homeostatic process GO:0042592 331 0.026
regulation of rna metabolic process GO:0051252 391 0.026
amine metabolic process GO:0009308 38 0.026
macromolecular complex subunit organization GO:0043933 339 0.026
response to wounding GO:0009611 254 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.026
neuron death GO:0070997 127 0.026
mesoderm development GO:0007498 2 0.025
cellular homeostasis GO:0019725 252 0.025
regulation of neuron apoptotic process GO:0043523 83 0.025
protein transport GO:0015031 132 0.025
positive regulation of transport GO:0051050 245 0.025
positive regulation of gene expression GO:0010628 244 0.025
regulation of apoptotic process GO:0042981 335 0.025
regulation of molecular function GO:0065009 398 0.025
protein complex subunit organization GO:0071822 302 0.025
positive regulation of programmed cell death GO:0043068 157 0.025
metal ion transport GO:0030001 289 0.025
Fly
embryonic cranial skeleton morphogenesis GO:0048701 2 0.025
positive regulation of cellular protein metabolic process GO:0032270 167 0.024
embryonic skeletal system morphogenesis GO:0048704 3 0.024
positive regulation of signal transduction GO:0009967 175 0.024
organelle organization GO:0006996 266 0.024
muscle system process GO:0003012 115 0.024
cellular ion homeostasis GO:0006873 184 0.024
regulation of synaptic transmission GO:0050804 141 0.024
renal system development GO:0072001 67 0.024
brain development GO:0007420 247 0.024
positive regulation of nervous system development GO:0051962 178 0.024
small gtpase mediated signal transduction GO:0007264 36 0.023
regulation of cellular ketone metabolic process GO:0010565 27 0.023
cellular component biogenesis GO:0044085 368 0.023
regulation of cell migration GO:0030334 128 0.023
regulation of protein metabolic process GO:0051246 289 0.023
regulation of neuron differentiation GO:0045664 208 0.023
positive regulation of phosphorylation GO:0042327 177 0.022
enzyme linked receptor protein signaling pathway GO:0007167 116 0.022
single organism intracellular transport GO:1902582 166 0.022
salivary gland development GO:0007431 3 0.022
regulation of protein phosphorylation GO:0001932 183 0.022
cellular amine metabolic process GO:0044106 38 0.022
positive regulation of transcription dna templated GO:0045893 197 0.022
multicellular organismal reproductive process GO:0048609 233 0.022
cell cell signaling GO:0007267 335 0.022
anterior posterior pattern specification GO:0009952 1 0.022
cell migration GO:0016477 197 0.022
nucleotide metabolic process GO:0009117 279 0.022
negative regulation of macromolecule metabolic process GO:0010605 260 0.022
positive regulation of cell differentiation GO:0045597 217 0.022
chemical homeostasis GO:0048878 292 0.021
nucleobase containing small molecule metabolic process GO:0055086 316 0.021
cellular component assembly GO:0022607 360 0.021
synaptic growth at neuromuscular junction GO:0051124 1 0.021
regulation of cell differentiation GO:0045595 320 0.021
positive regulation of signaling GO:0023056 270 0.021
regulation of kinase activity GO:0043549 117 0.021
positive regulation of neuron projection development GO:0010976 99 0.021
cytosolic calcium ion homeostasis GO:0051480 140 0.021
positive regulation of rna metabolic process GO:0051254 203 0.020
negative regulation of transport GO:0051051 136 0.020
positive regulation of multicellular organismal process GO:0051240 387 0.020
dendrite development GO:0016358 72 0.020
organic acid metabolic process GO:0006082 292 0.020
actin filament based process GO:0030029 86 0.020
positive regulation of cell death GO:0010942 184 0.020
response to peptide hormone GO:0043434 278 0.020
cation homeostasis GO:0055080 195 0.020
dna metabolic process GO:0006259 96 0.020
response to monosaccharide GO:0034284 159 0.020
cell motility GO:0048870 202 0.020
gastrulation GO:0007369 2 0.019
positive regulation of cell projection organization GO:0031346 111 0.019
positive regulation of protein modification process GO:0031401 142 0.019
ras protein signal transduction GO:0007265 29 0.019
cellular chemical homeostasis GO:0055082 247 0.019
embryonic appendage morphogenesis GO:0035113 4 0.019
head development GO:0060322 247 0.019
regulation of secretion by cell GO:1903530 208 0.019
single organism organelle organization GO:1902589 180 0.019
cellular response to endogenous stimulus GO:0071495 377 0.019
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.019
positive regulation of apoptotic process GO:0043065 154 0.019
positive regulation of protein metabolic process GO:0051247 178 0.019
response to vitamin GO:0033273 131 0.019
regulation of system process GO:0044057 208 0.019
actin cytoskeleton organization GO:0030036 73 0.019
tube development GO:0035295 89 0.019
cell morphogenesis involved in differentiation GO:0000904 119 0.019
vesicle mediated transport GO:0016192 181 0.018
localization of cell GO:0051674 202 0.018
response to oxygen levels GO:0070482 265 0.018
signal release GO:0023061 145 0.018
cellular divalent inorganic cation homeostasis GO:0072503 162 0.018
regulation of hormone levels GO:0010817 187 0.018
sexual reproduction GO:0019953 148 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
anion transport GO:0006820 178 0.018
carbohydrate metabolic process GO:0005975 130 0.018
negative regulation of nervous system development GO:0051961 79 0.018
regulation of anatomical structure morphogenesis GO:0022603 141 0.018
negative regulation of signaling GO:0023057 157 0.018
cellular response to stress GO:0033554 269 0.018
positive regulation of protein phosphorylation GO:0001934 135 0.018
transmembrane transport GO:0055085 412 0.017
Fly
cellular cation homeostasis GO:0030003 180 0.017
positive regulation of developmental process GO:0051094 283 0.017
positive regulation of protein kinase activity GO:0045860 73 0.017
response to cytokine GO:0034097 215 0.017
calcium ion homeostasis GO:0055074 162 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
ion homeostasis GO:0050801 212 0.017
ribonucleotide metabolic process GO:0009259 231 0.017
positive regulation of cell development GO:0010720 176 0.017
regulation of mapk cascade GO:0043408 116 0.017
intracellular protein transport GO:0006886 79 0.017
response to inorganic substance GO:0010035 377 0.017
single organism biosynthetic process GO:0044711 342 0.017
organ regeneration GO:0031100 101 0.017
positive regulation of rna biosynthetic process GO:1902680 197 0.017
mast cell migration GO:0097531 4 0.017
cation transport GO:0006812 382 0.017
Fly
response to extracellular stimulus GO:0009991 380 0.016
positive regulation of transferase activity GO:0051347 81 0.016
g protein coupled receptor signaling pathway GO:0007186 242 0.016
eye morphogenesis GO:0048592 4 0.016
behavior GO:0007610 205 0.016
regulation of protein kinase activity GO:0045859 105 0.016
developmental process involved in reproduction GO:0003006 159 0.016
positive regulation of neuron differentiation GO:0045666 126 0.016
single organism reproductive process GO:0044702 297 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
heart morphogenesis GO:0003007 3 0.016
cellular calcium ion homeostasis GO:0006874 160 0.016
macromolecule localization GO:0033036 252 0.016
regulation of neuron projection development GO:0010975 161 0.016
cellular amino acid metabolic process GO:0006520 107 0.016
cellular response to hormone stimulus GO:0032870 247 0.016
cellular component morphogenesis GO:0032989 155 0.016
neuron projection morphogenesis GO:0048812 122 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
negative regulation of rna biosynthetic process GO:1902679 118 0.016
nitrogen compound transport GO:0071705 229 0.015
heart development GO:0007507 72 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.015
response to hexose GO:0009746 144 0.015
heterocycle catabolic process GO:0046700 167 0.015
programmed cell death GO:0012501 392 0.015
regulation of growth GO:0040008 105 0.015
negative regulation of cell death GO:0060548 229 0.015
negative regulation of cell communication GO:0010648 158 0.015
cytoskeleton organization GO:0007010 111 0.015
regulation of dendrite development GO:0050773 59 0.015
response to carbohydrate GO:0009743 183 0.015
positive regulation of secretion GO:0051047 140 0.015
regulation of homeostatic process GO:0032844 101 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.014
inner ear receptor cell differentiation GO:0060113 2 0.014
cellular macromolecule localization GO:0070727 122 0.014
response to acid chemical GO:0001101 222 0.014
response to glucose GO:0009749 136 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.014
positive regulation of cellular component movement GO:0051272 102 0.014
axon development GO:0061564 96 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.014
growth GO:0040007 165 0.014
negative regulation of nucleic acid templated transcription GO:1903507 117 0.014
sex differentiation GO:0007548 113 0.014
single organism catabolic process GO:0044712 283 0.014
salivary gland morphogenesis GO:0007435 1 0.014
regulation of membrane potential GO:0042391 110 0.014
regulation of cellular localization GO:0060341 263 0.014
regulation of cellular component movement GO:0051270 150 0.014
neuronal action potential GO:0019228 35 0.014
signal transduction by phosphorylation GO:0023014 144 0.014
aging GO:0007568 241 0.014
dendrite morphogenesis GO:0048813 43 0.014
immune system process GO:0002376 204 0.014
camera type eye morphogenesis GO:0048593 2 0.014
single organism cellular localization GO:1902580 102 0.014
negative regulation of developmental process GO:0051093 125 0.014
negative regulation of neurogenesis GO:0050768 78 0.013
response to nutrient GO:0007584 248 0.013
mapk cascade GO:0000165 140 0.013
transmission of nerve impulse GO:0019226 42 0.013
cellular response to cytokine stimulus GO:0071345 127 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
response to lipopolysaccharide GO:0032496 191 0.013
regulation of stem cell differentiation GO:2000736 2 0.013
rhythmic process GO:0048511 156 0.013
intracellular transport GO:0046907 185 0.013
negative regulation of rna metabolic process GO:0051253 123 0.013
defense response GO:0006952 194 0.013
neurological system process GO:0050877 219 0.013
response to decreased oxygen levels GO:0036293 237 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.012
negative regulation of neuron differentiation GO:0045665 62 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
blood vessel development GO:0001568 69 0.012
embryonic pattern specification GO:0009880 1 0.012
gamete generation GO:0007276 124 0.012
cellular response to insulin stimulus GO:0032869 81 0.012
regeneration GO:0031099 163 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
synaptic transmission GO:0007268 235 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
amide transport GO:0042886 105 0.012
purine containing compound metabolic process GO:0072521 253 0.012
cell type specific apoptotic process GO:0097285 134 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
positive regulation of kinase activity GO:0033674 77 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
cellular response to lipid GO:0071396 201 0.012
molting cycle process GO:0022404 2 0.012
negative regulation of cellular protein metabolic process GO:0032269 106 0.012
response to other organism GO:0051707 220 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
axis specification GO:0009798 4 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
action potential GO:0001508 54 0.012
regulation of cell morphogenesis GO:0022604 77 0.012
multicellular organismal signaling GO:0035637 44 0.012
regulation of response to stress GO:0080134 126 0.012
kidney development GO:0001822 67 0.011
regulation of secretion GO:0051046 224 0.011
regulation of muscle system process GO:0090257 79 0.011
adult locomotory behavior GO:0008344 4 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
calcium ion transport GO:0006816 131 0.011
cellular lipid metabolic process GO:0044255 208 0.011
vasculature development GO:0001944 70 0.011
proteolysis GO:0006508 175 0.011
forebrain development GO:0030900 98 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.011
response to bacterium GO:0009617 200 0.011
cell cycle GO:0007049 101 0.011
positive regulation of neuron apoptotic process GO:0043525 33 0.011
rho protein signal transduction GO:0007266 11 0.011
regulation of cell development GO:0060284 263 0.011
response to external biotic stimulus GO:0043207 221 0.011
regulation of anatomical structure size GO:0090066 135 0.011
response to biotic stimulus GO:0009607 226 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
carbohydrate derivative metabolic process GO:1901135 346 0.011
telencephalon development GO:0021537 62 0.011
single organism behavior GO:0044708 130 0.011
organic anion transport GO:0015711 132 0.011
response to estradiol GO:0032355 164 0.011
cell growth GO:0016049 104 0.011
cell activation GO:0001775 97 0.011
gonad development GO:0008406 104 0.011
muscle cell proliferation GO:0033002 84 0.011
nucleoside metabolic process GO:0009116 179 0.011
response to hypoxia GO:0001666 231 0.011
synapse organization GO:0050808 46 0.011
Mouse
muscle structure development GO:0061061 87 0.011
lipid metabolic process GO:0006629 283 0.011
ion transmembrane transport GO:0034220 365 0.011
Fly
positive regulation of blood circulation GO:1903524 65 0.011
negative regulation of cell development GO:0010721 82 0.011
wound healing GO:0042060 122 0.011
developmental growth GO:0048589 100 0.011
catabolic process GO:0009056 351 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
hair cycle GO:0042633 3 0.011
metal ion homeostasis GO:0055065 186 0.011
cell chemotaxis GO:0060326 31 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
regulation of metal ion transport GO:0010959 118 0.011
regulation of small gtpase mediated signal transduction GO:0051056 48 0.010
response to peptide GO:1901652 292 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
mechanoreceptor differentiation GO:0042490 2 0.010
response to nutrient levels GO:0031667 370 0.010
divalent metal ion transport GO:0070838 132 0.010
negative regulation of cell differentiation GO:0045596 99 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.010
cytoplasmic transport GO:0016482 115 0.010
purine nucleotide catabolic process GO:0006195 136 0.010
axon guidance GO:0007411 24 0.010
regulation of cell proliferation GO:0042127 359 0.010
regulation of ion transport GO:0043269 245 0.010
regulation of fat cell differentiation GO:0045598 3 0.010
regulation of hormone secretion GO:0046883 106 0.010
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.010
regulation of establishment of protein localization GO:0070201 69 0.010
multi multicellular organism process GO:0044706 138 0.010
negative regulation of protein metabolic process GO:0051248 114 0.010
reactive nitrogen species metabolic process GO:2001057 1 0.010
urogenital system development GO:0001655 78 0.010
hormone secretion GO:0046879 115 0.010
myeloid leukocyte differentiation GO:0002573 20 0.010
protein complex biogenesis GO:0070271 263 0.010
carboxylic acid transport GO:0046942 115 0.010
rna localization GO:0006403 4 0.010

Pdzrn3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
sensory system disease DOID:0050155 0 0.016