Rattus norvegicus

0 known processes

Lgi4

leucine-rich repeat LGI family, member 4

Lgi4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nucleic acid templated transcription GO:0097659 379 0.091
rna metabolic process GO:0016070 406 0.072
regulation of rna biosynthetic process GO:2001141 381 0.070
regulation of nucleic acid templated transcription GO:1903506 380 0.070
cell projection organization GO:0030030 302 0.067
cellular response to endogenous stimulus GO:0071495 377 0.061
regulation of neuron differentiation GO:0045664 208 0.061
regulation of multicellular organismal development GO:2000026 376 0.059
regulation of cell differentiation GO:0045595 320 0.055
transcription dna templated GO:0006351 377 0.054
regulation of cellular component organization GO:0051128 368 0.051
cellular component biogenesis GO:0044085 368 0.051
Rat
response to inorganic substance GO:0010035 377 0.051
cellular component movement GO:0006928 248 0.050
anatomical structure morphogenesis GO:0009653 298 0.050
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.049
central nervous system development GO:0007417 311 0.046
regulation of rna metabolic process GO:0051252 391 0.045
macromolecule localization GO:0033036 252 0.045
positive regulation of multicellular organismal process GO:0051240 387 0.045
positive regulation of nervous system development GO:0051962 178 0.043
regulation of cell development GO:0060284 263 0.043
regulation of phosphorus metabolic process GO:0051174 349 0.042
regulation of nervous system development GO:0051960 264 0.042
rna biosynthetic process GO:0032774 380 0.041
transmembrane transport GO:0055085 412 0.041
cellular response to oxygen containing compound GO:1901701 386 0.041
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.040
neuron differentiation GO:0030182 368 0.040
carbohydrate derivative metabolic process GO:1901135 346 0.040
organophosphate metabolic process GO:0019637 370 0.040
response to extracellular stimulus GO:0009991 380 0.039
cellular component assembly GO:0022607 360 0.039
Rat
response to oxygen levels GO:0070482 265 0.038
oxoacid metabolic process GO:0043436 290 0.037
nucleobase containing small molecule metabolic process GO:0055086 316 0.037
protein localization GO:0008104 191 0.037
organic acid metabolic process GO:0006082 292 0.037
regulation of intracellular signal transduction GO:1902531 218 0.037
positive regulation of biosynthetic process GO:0009891 319 0.036
regulation of transcription dna templated GO:0006355 374 0.036
response to wounding GO:0009611 254 0.035
reproductive process GO:0022414 372 0.035
transcription from rna polymerase ii promoter GO:0006366 252 0.034
protein phosphorylation GO:0006468 345 0.034
response to nutrient levels GO:0031667 370 0.033
positive regulation of phosphorus metabolic process GO:0010562 262 0.033
positive regulation of cell death GO:0010942 184 0.032
negative regulation of cell differentiation GO:0045596 99 0.032
locomotion GO:0040011 237 0.032
positive regulation of cellular component organization GO:0051130 200 0.032
carboxylic acid metabolic process GO:0019752 289 0.032
response to other organism GO:0051707 220 0.032
localization of cell GO:0051674 202 0.032
regulation of neurogenesis GO:0050767 247 0.032
response to metal ion GO:0010038 253 0.032
negative regulation of metabolic process GO:0009892 331 0.031
regulation of phosphate metabolic process GO:0019220 349 0.031
ras protein signal transduction GO:0007265 29 0.031
protein complex assembly GO:0006461 263 0.030
Rat
ion transmembrane transport GO:0034220 365 0.030
programmed cell death GO:0012501 392 0.030
reproduction GO:0000003 245 0.030
neurological system process GO:0050877 219 0.030
regulation of cellular component movement GO:0051270 150 0.029
small gtpase mediated signal transduction GO:0007264 36 0.029
single organism catabolic process GO:0044712 283 0.029
multi organism reproductive process GO:0044703 262 0.029
protein complex biogenesis GO:0070271 263 0.029
Rat
regulation of protein metabolic process GO:0051246 289 0.028
regulation of nucleotide metabolic process GO:0006140 117 0.028
positive regulation of developmental process GO:0051094 283 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.028
neuron projection development GO:0031175 273 0.028
negative regulation of developmental process GO:0051093 125 0.027
cation transmembrane transport GO:0098655 263 0.027
positive regulation of cell differentiation GO:0045597 217 0.027
negative regulation of programmed cell death GO:0043069 183 0.027
cellular amino acid metabolic process GO:0006520 107 0.027
macromolecular complex assembly GO:0065003 273 0.027
Rat
cellular response to nitrogen compound GO:1901699 210 0.026
positive regulation of signaling GO:0023056 270 0.026
Rat
cell motility GO:0048870 202 0.026
positive regulation of gene expression GO:0010628 244 0.026
apoptotic process GO:0006915 381 0.026
response to lipopolysaccharide GO:0032496 191 0.026
protein complex subunit organization GO:0071822 302 0.026
Rat
monovalent inorganic cation transport GO:0015672 172 0.026
nucleoside phosphate metabolic process GO:0006753 283 0.026
response to acid chemical GO:0001101 222 0.025
negative regulation of macromolecule metabolic process GO:0010605 260 0.025
regulation of programmed cell death GO:0043067 341 0.025
cellular response to organonitrogen compound GO:0071417 197 0.025
multicellular organismal reproductive process GO:0048609 233 0.025
intracellular signal transduction GO:0035556 314 0.025
negative regulation of signaling GO:0023057 157 0.025
cell cell signaling GO:0007267 335 0.025
Rat
negative regulation of multicellular organismal process GO:0051241 203 0.025
cell adhesion GO:0007155 110 0.025
cell migration GO:0016477 197 0.024
amine metabolic process GO:0009308 38 0.024
response to alkaloid GO:0043279 132 0.024
regulation of apoptotic process GO:0042981 335 0.024
response to radiation GO:0009314 137 0.024
organelle organization GO:0006996 266 0.024
regulation of signal transduction GO:0009966 318 0.023
positive regulation of cell projection organization GO:0031346 111 0.023
response to mechanical stimulus GO:0009612 134 0.023
purine containing compound metabolic process GO:0072521 253 0.023
regulation of neuron projection development GO:0010975 161 0.023
positive regulation of cellular biosynthetic process GO:0031328 295 0.023
single organism organelle organization GO:1902589 180 0.023
cellular response to peptide hormone stimulus GO:0071375 120 0.023
aging GO:0007568 241 0.022
regulation of anatomical structure morphogenesis GO:0022603 141 0.022
cellular response to lipid GO:0071396 201 0.022
multicellular organism reproduction GO:0032504 233 0.022
cellular catabolic process GO:0044248 295 0.022
response to ethanol GO:0045471 162 0.022
positive regulation of nucleic acid templated transcription GO:1903508 197 0.022
cellular amine metabolic process GO:0044106 38 0.022
positive regulation of rna metabolic process GO:0051254 203 0.022
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.022
sexual reproduction GO:0019953 148 0.022
ribose phosphate metabolic process GO:0019693 235 0.022
response to molecule of bacterial origin GO:0002237 194 0.022
intracellular transport GO:0046907 185 0.022
single organism reproductive process GO:0044702 297 0.022
regulation of cellular localization GO:0060341 263 0.021
regulation of molecular function GO:0065009 398 0.021
neuron development GO:0048666 286 0.021
negative regulation of cellular metabolic process GO:0031324 281 0.021
response to growth factor GO:0070848 189 0.021
gliogenesis GO:0042063 93 0.021
response to peptide hormone GO:0043434 278 0.021
positive regulation of response to stimulus GO:0048584 285 0.021
positive regulation of neurogenesis GO:0050769 165 0.021
nucleotide metabolic process GO:0009117 279 0.021
brain development GO:0007420 247 0.021
negative regulation of rna biosynthetic process GO:1902679 118 0.021
positive regulation of cell communication GO:0010647 271 0.020
Rat
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.020
regulation of protein phosphorylation GO:0001932 183 0.020
cellular homeostasis GO:0019725 252 0.020
negative regulation of nucleic acid templated transcription GO:1903507 117 0.020
cellular ketone metabolic process GO:0042180 51 0.020
regulation of secretion GO:0051046 224 0.020
response to cytokine GO:0034097 215 0.020
cellular protein localization GO:0034613 122 0.020
nucleoside metabolic process GO:0009116 179 0.020
regeneration GO:0031099 163 0.020
cellular macromolecule localization GO:0070727 122 0.020
macromolecular complex subunit organization GO:0043933 339 0.020
Rat
positive regulation of transcription dna templated GO:0045893 197 0.020
catabolic process GO:0009056 351 0.020
ribonucleotide metabolic process GO:0009259 231 0.020
secretion GO:0046903 307 0.019
wound healing GO:0042060 122 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
response to nutrient GO:0007584 248 0.019
regulation of catalytic activity GO:0050790 304 0.019
positive regulation of rna biosynthetic process GO:1902680 197 0.019
negative regulation of cell communication GO:0010648 158 0.019
negative regulation of neurogenesis GO:0050768 78 0.019
regulation of cell projection organization GO:0031344 175 0.019
negative regulation of cell development GO:0010721 82 0.019
positive regulation of programmed cell death GO:0043068 157 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
anterior posterior pattern specification GO:0009952 1 0.018
regulation of cell proliferation GO:0042127 359 0.018
regulation of phosphorylation GO:0042325 248 0.018
negative regulation of cellular biosynthetic process GO:0031327 161 0.018
response to estrogen GO:0043627 232 0.018
cellular response to hormone stimulus GO:0032870 247 0.018
single organism biosynthetic process GO:0044711 342 0.018
positive regulation of cell proliferation GO:0008284 249 0.018
negative regulation of gene expression GO:0010629 199 0.018
metal ion transport GO:0030001 289 0.018
regulation of ion transport GO:0043269 245 0.018
cellular nitrogen compound catabolic process GO:0044270 163 0.018
organophosphate biosynthetic process GO:0090407 143 0.018
negative regulation of cellular component organization GO:0051129 83 0.018
regulation of purine nucleotide metabolic process GO:1900542 115 0.018
negative regulation of transcription dna templated GO:0045892 116 0.018
purine ribonucleotide metabolic process GO:0009150 227 0.018
head development GO:0060322 247 0.018
organonitrogen compound catabolic process GO:1901565 179 0.018
response to decreased oxygen levels GO:0036293 237 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.018
positive regulation of apoptotic process GO:0043065 154 0.017
negative regulation of cell death GO:0060548 229 0.017
regulation of cell migration GO:0030334 128 0.017
cellular chemical homeostasis GO:0055082 247 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
organic acid transport GO:0015849 116 0.017
positive regulation of cell development GO:0010720 176 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
cellular response to stress GO:0033554 269 0.017
heterocycle catabolic process GO:0046700 167 0.017
regulation of cellular protein metabolic process GO:0032268 267 0.017
nitrogen compound transport GO:0071705 229 0.017
ion homeostasis GO:0050801 212 0.017
anatomical structure formation involved in morphogenesis GO:0048646 83 0.017
cellular response to organic cyclic compound GO:0071407 202 0.017
aromatic compound catabolic process GO:0019439 168 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
rhythmic process GO:0048511 156 0.016
positive regulation of phosphate metabolic process GO:0045937 262 0.016
regulation of secretion by cell GO:1903530 208 0.016
negative regulation of transport GO:0051051 136 0.016
inorganic cation transmembrane transport GO:0098662 202 0.016
action potential GO:0001508 54 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
chemical homeostasis GO:0048878 292 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
establishment of protein localization GO:0045184 141 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
positive regulation of molecular function GO:0044093 230 0.016
biological adhesion GO:0022610 110 0.016
regulation of cell motility GO:2000145 131 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
cellular component morphogenesis GO:0032989 155 0.016
response to oxidative stress GO:0006979 186 0.015
response to camp GO:0051591 91 0.015
circulatory system development GO:0072359 134 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
blood vessel development GO:0001568 69 0.015
regulation of protein modification process GO:0031399 194 0.015
regulation of transmembrane transport GO:0034762 122 0.015
gamete generation GO:0007276 124 0.015
negative regulation of nervous system development GO:0051961 79 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
regulation of protein kinase activity GO:0045859 105 0.015
oxidation reduction process GO:0055114 304 0.015
cardiovascular system development GO:0072358 134 0.015
positive regulation of secretion GO:0051047 140 0.015
cell morphogenesis GO:0000902 142 0.015
response to ketone GO:1901654 182 0.015
anion transport GO:0006820 178 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.015
carbohydrate derivative catabolic process GO:1901136 147 0.015
organophosphate catabolic process GO:0046434 148 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
blood circulation GO:0008015 183 0.014
single organism intracellular transport GO:1902582 166 0.014
response to external biotic stimulus GO:0043207 221 0.014
gastrulation GO:0007369 2 0.014
regulation of small gtpase mediated signal transduction GO:0051056 48 0.014
cellular response to acid chemical GO:0071229 75 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
gonad development GO:0008406 104 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
negative regulation of neuron differentiation GO:0045665 62 0.014
developmental growth GO:0048589 100 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.014
inflammatory response GO:0006954 150 0.014
axis specification GO:0009798 4 0.013
metal ion homeostasis GO:0055065 186 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
rho protein signal transduction GO:0007266 11 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
negative regulation of rna metabolic process GO:0051253 123 0.013
response to hypoxia GO:0001666 231 0.013
ribose phosphate biosynthetic process GO:0046390 87 0.013
protein oligomerization GO:0051259 191 0.013
Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
nucleoside triphosphate catabolic process GO:0009143 123 0.013
response to corticosteroid GO:0031960 235 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
response to vitamin GO:0033273 131 0.013
peptidyl amino acid modification GO:0018193 126 0.013
cation transport GO:0006812 382 0.013
negative regulation of cell proliferation GO:0008285 119 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
regulation of hydrolase activity GO:0051336 143 0.013
behavior GO:0007610 205 0.013
regulation of system process GO:0044057 208 0.013
muscle system process GO:0003012 115 0.013
heart morphogenesis GO:0003007 3 0.013
regulation of response to external stimulus GO:0032101 106 0.013
regulation of membrane potential GO:0042391 110 0.013
protein heterooligomerization GO:0051291 89 0.013
response to toxic substance GO:0009636 133 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.012
intracellular protein transport GO:0006886 79 0.012
cellular response to metal ion GO:0071248 55 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
cation homeostasis GO:0055080 195 0.012
cellular cation homeostasis GO:0030003 180 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
growth GO:0040007 165 0.012
response to amino acid GO:0043200 75 0.012
positive regulation of protein modification process GO:0031401 142 0.012
purine nucleoside triphosphate metabolic process GO:0009144 141 0.012
nucleoside catabolic process GO:0009164 126 0.012
regulation of synaptic transmission GO:0050804 141 0.012
Rat
regulation of anatomical structure size GO:0090066 135 0.012
cell part morphogenesis GO:0032990 123 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
organic substance catabolic process GO:1901575 316 0.012
lipid metabolic process GO:0006629 283 0.012
ribonucleoside triphosphate metabolic process GO:0009199 141 0.012
glial cell differentiation GO:0010001 65 0.012
response to retinoic acid GO:0032526 63 0.012
response to purine containing compound GO:0014074 126 0.012
chromosome segregation GO:0007059 2 0.012
protein transport GO:0015031 132 0.012
response to biotic stimulus GO:0009607 226 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
developmental process involved in reproduction GO:0003006 159 0.012
spindle organization GO:0007051 2 0.012
cytoskeleton organization GO:0007010 111 0.012
membrane organization GO:0061024 94 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
positive regulation of ion transport GO:0043270 94 0.012
response to bacterium GO:0009617 200 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
negative regulation of molecular function GO:0044092 133 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
single organism behavior GO:0044708 130 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
motor neuron axon guidance GO:0008045 1 0.011
regulation of homotypic cell cell adhesion GO:0034110 4 0.011
proteolysis GO:0006508 175 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
regulation of locomotion GO:0040012 148 0.011
transmission of nerve impulse GO:0019226 42 0.011
axonogenesis GO:0007409 71 0.011
purine containing compound catabolic process GO:0072523 138 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
cytoplasmic transport GO:0016482 115 0.011
neuron death GO:0070997 127 0.011
learning or memory GO:0007611 90 0.011
cell projection morphogenesis GO:0048858 123 0.011
chemosensory behavior GO:0007635 2 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
regulation of kinase activity GO:0043549 117 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
embryonic pattern specification GO:0009880 1 0.011
positive regulation of transport GO:0051050 245 0.011
regulation of mapk cascade GO:0043408 116 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
response to reactive oxygen species GO:0000302 120 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
cell type specific apoptotic process GO:0097285 134 0.011
synaptic transmission GO:0007268 235 0.011
Rat
ribonucleoside triphosphate catabolic process GO:0009203 122 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.010
cytosolic calcium ion homeostasis GO:0051480 140 0.010
negative regulation of protein metabolic process GO:0051248 114 0.010
purine ribonucleotide catabolic process GO:0009154 136 0.010
sensory perception of pain GO:0019233 73 0.010
nucleotide catabolic process GO:0009166 139 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.010
calcium ion homeostasis GO:0055074 162 0.010
regulation of cell adhesion GO:0030155 52 0.010
homeostatic process GO:0042592 331 0.010
cellular ion homeostasis GO:0006873 184 0.010
response to peptide GO:1901652 292 0.010
cellular response to extracellular stimulus GO:0031668 73 0.010
peptide transport GO:0015833 97 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.010
regulation of hormone levels GO:0010817 187 0.010
nucleotide biosynthetic process GO:0009165 98 0.010
purine nucleotide catabolic process GO:0006195 136 0.010
male gamete generation GO:0048232 99 0.010
organic anion transport GO:0015711 132 0.010

Lgi4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.032
disease of anatomical entity DOID:7 0 0.032
eye and adnexa disease DOID:1492 0 0.017
sensory system disease DOID:0050155 0 0.017
eye disease DOID:5614 0 0.017
musculoskeletal system disease DOID:17 0 0.015
disease of metabolism DOID:0014667 0 0.011
muscular disease DOID:0080000 0 0.011
muscle tissue disease DOID:66 0 0.011
connective tissue disease DOID:65 0 0.010
bone disease DOID:0080001 0 0.010
central nervous system disease DOID:331 0 0.010