Rattus norvegicus

0 known processes

Herc4

hect domain and RLD 4

Herc4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to external biotic stimulus GO:0043207 221 0.072
regulation of multicellular organismal development GO:2000026 376 0.064
immune response GO:0006955 104 0.061
negative regulation of multicellular organismal process GO:0051241 203 0.060
regulation of apoptotic process GO:0042981 335 0.054
response to toxic substance GO:0009636 133 0.054
regulation of rna biosynthetic process GO:2001141 381 0.050
carbohydrate metabolic process GO:0005975 130 0.050
intracellular signal transduction GO:0035556 314 0.049
macromolecule localization GO:0033036 252 0.048
protein phosphorylation GO:0006468 345 0.047
response to oxidative stress GO:0006979 186 0.046
muscle system process GO:0003012 115 0.046
immune system process GO:0002376 204 0.045
protein autophosphorylation GO:0046777 66 0.044
neurological system process GO:0050877 219 0.044
single organism carbohydrate metabolic process GO:0044723 118 0.044
regulation of programmed cell death GO:0043067 341 0.043
response to biotic stimulus GO:0009607 226 0.042
catabolic process GO:0009056 351 0.041
response to bacterium GO:0009617 200 0.041
negative regulation of signal transduction GO:0009968 83 0.040
cation transport GO:0006812 382 0.040
cellular ketone metabolic process GO:0042180 51 0.039
apoptotic process GO:0006915 381 0.039
transmembrane transport GO:0055085 412 0.038
regulation of response to stress GO:0080134 126 0.038
inorganic cation transmembrane transport GO:0098662 202 0.038
positive regulation of cell death GO:0010942 184 0.038
positive regulation of apoptotic process GO:0043065 154 0.037
negative regulation of metabolic process GO:0009892 331 0.036
cellular response to stress GO:0033554 269 0.035
response to acid chemical GO:0001101 222 0.035
regulation of nucleic acid templated transcription GO:1903506 380 0.035
negative regulation of response to stimulus GO:0048585 155 0.033
response to peptide GO:1901652 292 0.033
transcription dna templated GO:0006351 377 0.033
cellular component biogenesis GO:0044085 368 0.032
regulation of immune system process GO:0002682 123 0.032
regulation of transcription dna templated GO:0006355 374 0.031
synaptic growth at neuromuscular junction GO:0051124 1 0.031
metal ion transport GO:0030001 289 0.031
homeostatic process GO:0042592 331 0.031
negative regulation of cellular metabolic process GO:0031324 281 0.031
cellular cation homeostasis GO:0030003 180 0.031
secretion GO:0046903 307 0.031
positive regulation of programmed cell death GO:0043068 157 0.030
regulation of cellular localization GO:0060341 263 0.030
cellular response to hormone stimulus GO:0032870 247 0.029
nucleic acid templated transcription GO:0097659 379 0.029
ion transmembrane transport GO:0034220 365 0.029
metal ion homeostasis GO:0055065 186 0.029
regulation of cellular ketone metabolic process GO:0010565 27 0.029
head development GO:0060322 247 0.028
chemical homeostasis GO:0048878 292 0.028
positive regulation of transport GO:0051050 245 0.028
response to cytokine GO:0034097 215 0.027
cation transmembrane transport GO:0098655 263 0.027
mapk cascade GO:0000165 140 0.026
organic substance catabolic process GO:1901575 316 0.026
regulation of system process GO:0044057 208 0.025
regulation of cellular component organization GO:0051128 368 0.025
response to other organism GO:0051707 220 0.025
cellular amino acid metabolic process GO:0006520 107 0.025
negative regulation of macromolecule metabolic process GO:0010605 260 0.025
multicellular organismal reproductive process GO:0048609 233 0.025
Mouse
negative regulation of developmental process GO:0051093 125 0.025
regulation of cell differentiation GO:0045595 320 0.024
multicellular organism reproduction GO:0032504 233 0.024
Mouse
regulation of cellular catabolic process GO:0031329 101 0.024
regulation of cellular response to stress GO:0080135 49 0.023
response to molecule of bacterial origin GO:0002237 194 0.023
negative regulation of transport GO:0051051 136 0.023
regulation of molecular function GO:0065009 398 0.023
neuron differentiation GO:0030182 368 0.023
response to mechanical stimulus GO:0009612 134 0.023
macromolecular complex subunit organization GO:0043933 339 0.022
negative regulation of programmed cell death GO:0043069 183 0.021
regulation of catabolic process GO:0009894 113 0.021
regulation of nucleobase containing compound transport GO:0032239 1 0.021
regulation of protein metabolic process GO:0051246 289 0.021
positive regulation of phosphorylation GO:0042327 177 0.021
regulation of intracellular signal transduction GO:1902531 218 0.021
neuron development GO:0048666 286 0.021
b cell activation involved in immune response GO:0002312 1 0.021
rna biosynthetic process GO:0032774 380 0.021
cellular amine metabolic process GO:0044106 38 0.021
positive regulation of biosynthetic process GO:0009891 319 0.021
regulation of secretion GO:0051046 224 0.020
rhythmic process GO:0048511 156 0.020
cellular chemical homeostasis GO:0055082 247 0.020
response to radiation GO:0009314 137 0.020
multi organism reproductive process GO:0044703 262 0.020
Mouse
negative regulation of gene expression GO:0010629 199 0.020
lipid metabolic process GO:0006629 283 0.020
regulation of phosphorylation GO:0042325 248 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.020
cellular response to cytokine stimulus GO:0071345 127 0.019
establishment of protein localization GO:0045184 141 0.019
response to carbohydrate GO:0009743 183 0.019
central nervous system development GO:0007417 311 0.019
programmed cell death GO:0012501 392 0.018
single organism biosynthetic process GO:0044711 342 0.018
positive regulation of developmental process GO:0051094 283 0.018
anatomical structure morphogenesis GO:0009653 298 0.018
reproduction GO:0000003 245 0.018
Mouse
regulation of immunoglobulin production GO:0002637 4 0.018
oxidation reduction process GO:0055114 304 0.018
regulation of nervous system development GO:0051960 264 0.018
macromolecular complex assembly GO:0065003 273 0.018
negative regulation of signaling GO:0023057 157 0.018
nitrogen compound transport GO:0071705 229 0.018
protein oligomerization GO:0051259 191 0.018
protein complex subunit organization GO:0071822 302 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
cellular response to oxygen containing compound GO:1901701 386 0.018
negative regulation of cellular biosynthetic process GO:0031327 161 0.018
intracellular transport GO:0046907 185 0.017
cellular component morphogenesis GO:0032989 155 0.017
regulation of protein modification process GO:0031399 194 0.017
protein catabolic process GO:0030163 30 0.017
negative regulation of molecular function GO:0044092 133 0.017
monosaccharide metabolic process GO:0005996 61 0.017
regulation of mapk cascade GO:0043408 116 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
cell cell signaling GO:0007267 335 0.016
carboxylic acid metabolic process GO:0019752 289 0.016
generation of precursor metabolites and energy GO:0006091 62 0.016
response to vitamin GO:0033273 131 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
brain development GO:0007420 247 0.016
single organism intracellular transport GO:1902582 166 0.016
regulation of homeostatic process GO:0032844 101 0.016
proteolysis GO:0006508 175 0.016
regulation of immunoglobulin mediated immune response GO:0002889 2 0.016
muscle contraction GO:0006936 88 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
amine metabolic process GO:0009308 38 0.016
regulation of cell cycle GO:0051726 73 0.016
ion homeostasis GO:0050801 212 0.016
secretion by cell GO:0032940 248 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
defense response GO:0006952 194 0.016
regulation of b cell mediated immunity GO:0002712 2 0.015
mesoderm development GO:0007498 2 0.015
regulation of cell development GO:0060284 263 0.015
regulation of membrane potential GO:0042391 110 0.015
blood circulation GO:0008015 183 0.015
response to wounding GO:0009611 254 0.015
positive regulation of response to stimulus GO:0048584 285 0.015
cellular response to lipid GO:0071396 201 0.015
neuron projection development GO:0031175 273 0.015
regulation of signal transduction GO:0009966 318 0.015
rna localization GO:0006403 4 0.015
response to decreased oxygen levels GO:0036293 237 0.015
single organism reproductive process GO:0044702 297 0.015
Mouse
inorganic ion transmembrane transport GO:0098660 229 0.015
cellular catabolic process GO:0044248 295 0.015
response to glucose GO:0009749 136 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.015
organophosphate metabolic process GO:0019637 370 0.015
gamete generation GO:0007276 124 0.015
Mouse
endocytosis GO:0006897 84 0.014
cellular component assembly GO:0022607 360 0.014
regulation of catalytic activity GO:0050790 304 0.014
cellular homeostasis GO:0019725 252 0.014
negative regulation of cell communication GO:0010648 158 0.014
response to inorganic substance GO:0010035 377 0.014
regulation of isotype switching GO:0045191 1 0.014
reproductive system development GO:0061458 128 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
dna metabolic process GO:0006259 96 0.014
cytoplasmic transport GO:0016482 115 0.014
divalent inorganic cation transport GO:0072511 134 0.014
cell projection organization GO:0030030 302 0.014
rho protein signal transduction GO:0007266 11 0.014
protein localization GO:0008104 191 0.014
vesicle mediated transport GO:0016192 181 0.014
multi multicellular organism process GO:0044706 138 0.014
locomotion GO:0040011 237 0.014
cellular component movement GO:0006928 248 0.014
hexose metabolic process GO:0019318 58 0.013
response to light stimulus GO:0009416 52 0.013
regulation of immune response GO:0050776 55 0.013
response to oxygen levels GO:0070482 265 0.013
organelle organization GO:0006996 266 0.013
reproductive process GO:0022414 372 0.013
Mouse
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
regulation of muscle system process GO:0090257 79 0.013
axis specification GO:0009798 4 0.013
lymphocyte activation involved in immune response GO:0002285 3 0.013
macromolecule catabolic process GO:0009057 58 0.013
positive regulation of multicellular organismal process GO:0051240 387 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
positive regulation of phosphate metabolic process GO:0045937 262 0.013
rna metabolic process GO:0016070 406 0.013
oxoacid metabolic process GO:0043436 290 0.013
negative regulation of insulin receptor signaling pathway GO:0046627 10 0.013
negative regulation of cell cycle phase transition GO:1901988 4 0.013
regulation of dna metabolic process GO:0051052 60 0.013
divalent metal ion transport GO:0070838 132 0.013
maintenance of location GO:0051235 17 0.013
positive regulation of protein metabolic process GO:0051247 178 0.012
positive regulation of molecular function GO:0044093 230 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
response to hydrogen peroxide GO:0042542 89 0.012
negative regulation of phosphate metabolic process GO:0045936 80 0.012
regulation of phosphorus metabolic process GO:0051174 349 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
action potential GO:0001508 54 0.012
regulation of leukocyte activation GO:0002694 45 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
chemosensory behavior GO:0007635 2 0.012
cell part morphogenesis GO:0032990 123 0.012
programmed necrotic cell death GO:0097300 2 0.012
calcium ion transport GO:0006816 131 0.012
positive regulation of nervous system development GO:0051962 178 0.012
response to amino acid GO:0043200 75 0.012
glucose metabolic process GO:0006006 52 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
ras protein signal transduction GO:0007265 29 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
positive regulation of cell development GO:0010720 176 0.011
lipid storage GO:0019915 1 0.011
regulation of stress activated mapk cascade GO:0032872 23 0.011
cell activation GO:0001775 97 0.011
response to monosaccharide GO:0034284 159 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
cytoskeleton organization GO:0007010 111 0.011
tissue development GO:0009888 252 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
striated muscle contraction GO:0006941 44 0.011
female sex differentiation GO:0046660 59 0.011
cell cycle checkpoint GO:0000075 2 0.011
sexual reproduction GO:0019953 148 0.011
Mouse
response to extracellular stimulus GO:0009991 380 0.011
cellular response to endogenous stimulus GO:0071495 377 0.011
cell cycle GO:0007049 101 0.011
regulation of cell projection organization GO:0031344 175 0.011
cholesterol homeostasis GO:0042632 3 0.011
negative regulation of neuron differentiation GO:0045665 62 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
learning or memory GO:0007611 90 0.011
response to ketone GO:1901654 182 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
cellular ion homeostasis GO:0006873 184 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
b cell mediated immunity GO:0019724 4 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.011
regulation of neurogenesis GO:0050767 247 0.011
positive regulation of cell differentiation GO:0045597 217 0.010
response to nutrient GO:0007584 248 0.010
regulation of secretion by cell GO:1903530 208 0.010
positive regulation of mapk cascade GO:0043410 92 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.010
anion transport GO:0006820 178 0.010
carbohydrate derivative metabolic process GO:1901135 346 0.010
regulation of ion transport GO:0043269 245 0.010
behavior GO:0007610 205 0.010
response to glucocorticoid GO:0051384 223 0.010
membrane organization GO:0061024 94 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.010
organonitrogen compound catabolic process GO:1901565 179 0.010
transcription from rna polymerase ii promoter GO:0006366 252 0.010

Herc4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
disease of metabolism DOID:0014667 0 0.010