Rattus norvegicus

10 known processes

Alk

anaplastic lymphoma kinase

Alk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transmembrane transport GO:0055085 412 0.092
intracellular signal transduction GO:0035556 314 0.079
Fly
organic acid metabolic process GO:0006082 292 0.069
response to peptide hormone GO:0043434 278 0.063
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.060
Rat
rna metabolic process GO:0016070 406 0.059
neurological system process GO:0050877 219 0.056
Fly
protein phosphorylation GO:0006468 345 0.052
Human Rat Fly
response to inorganic substance GO:0010035 377 0.050
Rat
positive regulation of gene expression GO:0010628 244 0.047
oxoacid metabolic process GO:0043436 290 0.046
anatomical structure morphogenesis GO:0009653 298 0.045
Rat Fly
cellular response to endogenous stimulus GO:0071495 377 0.045
Rat
response to extracellular stimulus GO:0009991 380 0.044
Rat
ion transmembrane transport GO:0034220 365 0.042
metal ion transport GO:0030001 289 0.042
head development GO:0060322 247 0.039
regulation of nucleic acid templated transcription GO:1903506 380 0.039
cellular component biogenesis GO:0044085 368 0.039
Rat
divalent metal ion transport GO:0070838 132 0.038
lipid metabolic process GO:0006629 283 0.037
Rat
carboxylic acid metabolic process GO:0019752 289 0.036
response to nutrient levels GO:0031667 370 0.036
Rat
macromolecular complex subunit organization GO:0043933 339 0.036
Rat
behavior GO:0007610 205 0.035
Fly
negative regulation of metabolic process GO:0009892 331 0.035
Rat
regulation of neurogenesis GO:0050767 247 0.034
regulation of cell differentiation GO:0045595 320 0.034
Fly
regulation of transcription dna templated GO:0006355 374 0.034
single organism behavior GO:0044708 130 0.033
Fly
regulation of cellular amine metabolic process GO:0033238 8 0.033
rna biosynthetic process GO:0032774 380 0.032
cellular ketone metabolic process GO:0042180 51 0.032
cellular component assembly GO:0022607 360 0.032
Rat
homeostatic process GO:0042592 331 0.032
Rat
regulation of rna biosynthetic process GO:2001141 381 0.031
regulation of phosphate metabolic process GO:0019220 349 0.031
Rat Fly
response to oxidative stress GO:0006979 186 0.031
neuron development GO:0048666 286 0.031
Rat Fly
cellular response to oxygen containing compound GO:1901701 386 0.030
Rat
central nervous system development GO:0007417 311 0.030
regulation of cellular protein metabolic process GO:0032268 267 0.030
Rat Fly
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.029
Rat
regulation of system process GO:0044057 208 0.029
Fly
monovalent inorganic cation transport GO:0015672 172 0.029
positive regulation of rna biosynthetic process GO:1902680 197 0.028
positive regulation of molecular function GO:0044093 230 0.028
Fly
positive regulation of cell death GO:0010942 184 0.028
macromolecular complex assembly GO:0065003 273 0.028
Rat
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.028
Rat
regulation of protein metabolic process GO:0051246 289 0.028
Rat Fly
protein complex assembly GO:0006461 263 0.027
Rat
regulation of molecular function GO:0065009 398 0.027
Rat Fly
cell part morphogenesis GO:0032990 123 0.027
Rat Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.027
positive regulation of cell differentiation GO:0045597 217 0.026
cellular amino acid metabolic process GO:0006520 107 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
Rat
response to insulin GO:0032868 133 0.026
Rat
cellular component movement GO:0006928 248 0.026
Fly
response to acid chemical GO:0001101 222 0.026
response to molecule of bacterial origin GO:0002237 194 0.026
brain development GO:0007420 247 0.026
single organism catabolic process GO:0044712 283 0.026
response to peptide GO:1901652 292 0.026
Rat
response to glucocorticoid GO:0051384 223 0.025
Rat
cell projection organization GO:0030030 302 0.025
Rat Fly
neuron differentiation GO:0030182 368 0.025
Rat Fly
regulation of cellular component organization GO:0051128 368 0.025
regulation of cell development GO:0060284 263 0.024
potassium ion transport GO:0006813 97 0.024
regulation of cell projection organization GO:0031344 175 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.024
amine metabolic process GO:0009308 38 0.024
organelle organization GO:0006996 266 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
Rat Fly
regulation of cellular localization GO:0060341 263 0.024
apoptotic process GO:0006915 381 0.024
Rat
positive regulation of nucleic acid templated transcription GO:1903508 197 0.023
positive regulation of cellular amine metabolic process GO:0033240 3 0.023
cation transmembrane transport GO:0098655 263 0.023
cellular response to acid chemical GO:0071229 75 0.023
regulation of programmed cell death GO:0043067 341 0.023
Rat
cation transport GO:0006812 382 0.023
transcription dna templated GO:0006351 377 0.023
regulation of nervous system development GO:0051960 264 0.023
negative regulation of multicellular organismal process GO:0051241 203 0.022
cell migration GO:0016477 197 0.022
regulation of neuron differentiation GO:0045664 208 0.022
positive regulation of neurogenesis GO:0050769 165 0.022
cellular amine metabolic process GO:0044106 38 0.022
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
blood circulation GO:0008015 183 0.022
muscle system process GO:0003012 115 0.022
response to oxygen levels GO:0070482 265 0.021
heart morphogenesis GO:0003007 3 0.021
positive regulation of rna metabolic process GO:0051254 203 0.021
circulatory system process GO:0003013 183 0.021
negative regulation of cellular metabolic process GO:0031324 281 0.021
Rat
cardiac conduction GO:0061337 2 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
regulation of signal transduction GO:0009966 318 0.020
Fly
positive regulation of biosynthetic process GO:0009891 319 0.020
Rat
cellular component morphogenesis GO:0032989 155 0.020
Rat Fly
secretion by cell GO:0032940 248 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
cellular chemical homeostasis GO:0055082 247 0.020
cell cell signaling GO:0007267 335 0.020
Fly
cellular response to stress GO:0033554 269 0.020
response to wounding GO:0009611 254 0.019
intracellular transport GO:0046907 185 0.019
response to glucose GO:0009749 136 0.019
Rat
regulation of ion transmembrane transport GO:0034765 121 0.019
reproduction GO:0000003 245 0.019
cellular response to organonitrogen compound GO:0071417 197 0.019
Rat
cation homeostasis GO:0055080 195 0.019
negative regulation of neuron differentiation GO:0045665 62 0.019
single organism reproductive process GO:0044702 297 0.019
signal release GO:0023061 145 0.019
defense response GO:0006952 194 0.018
positive regulation of protein modification process GO:0031401 142 0.018
Fly
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
Rat
negative regulation of response to external stimulus GO:0032102 37 0.018
cellular response to nitrogen compound GO:1901699 210 0.018
Rat
cell morphogenesis GO:0000902 142 0.018
Rat Fly
inorganic ion transmembrane transport GO:0098660 229 0.018
positive regulation of protein phosphorylation GO:0001934 135 0.018
Fly
cellular ion homeostasis GO:0006873 184 0.018
regulation of rna metabolic process GO:0051252 391 0.018
organic hydroxy compound metabolic process GO:1901615 115 0.018
reproductive process GO:0022414 372 0.018
vesicle mediated transport GO:0016192 181 0.018
positive regulation of transcription dna templated GO:0045893 197 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.017
nucleobase containing small molecule metabolic process GO:0055086 316 0.017
response to nutrient GO:0007584 248 0.017
Rat
response to camp GO:0051591 91 0.017
cellular homeostasis GO:0019725 252 0.017
response to ethanol GO:0045471 162 0.017
Rat
positive regulation of kinase activity GO:0033674 77 0.017
Fly
regulation of response to external stimulus GO:0032101 106 0.017
negative regulation of response to stimulus GO:0048585 155 0.017
programmed cell death GO:0012501 392 0.017
Rat
cognition GO:0050890 92 0.017
Fly
negative regulation of protein metabolic process GO:0051248 114 0.017
Rat
regulation of membrane potential GO:0042391 110 0.017
multi organism reproductive process GO:0044703 262 0.017
calcium ion transport GO:0006816 131 0.017
response to corticosteroid GO:0031960 235 0.017
Rat
positive regulation of cell proliferation GO:0008284 249 0.016
neuronal action potential GO:0019228 35 0.016
ion homeostasis GO:0050801 212 0.016
neural crest cell differentiation GO:0014033 2 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
regulation of intracellular signal transduction GO:1902531 218 0.016
Fly
glycosyl compound metabolic process GO:1901657 182 0.016
organophosphate metabolic process GO:0019637 370 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
Rat Fly
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
Fly
carbohydrate derivative metabolic process GO:1901135 346 0.016
Rat
inflammatory response GO:0006954 150 0.016
regulation of neuron projection development GO:0010975 161 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.016
multicellular organismal signaling GO:0035637 44 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.015
cell projection morphogenesis GO:0048858 123 0.015
Rat Fly
regulation of hormone levels GO:0010817 187 0.015
Rat
negative regulation of cell communication GO:0010648 158 0.015
Fly
chemical homeostasis GO:0048878 292 0.015
Rat
cellular response to lipid GO:0071396 201 0.015
cellular metal ion homeostasis GO:0006875 172 0.015
regulation of protein modification process GO:0031399 194 0.015
Rat Fly
action potential GO:0001508 54 0.015
inorganic cation transmembrane transport GO:0098662 202 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
protein complex biogenesis GO:0070271 263 0.015
Rat
secretion GO:0046903 307 0.015
response to external biotic stimulus GO:0043207 221 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
Rat Fly
negative regulation of apoptotic process GO:0043066 181 0.015
Rat
response to radiation GO:0009314 137 0.015
purine containing compound metabolic process GO:0072521 253 0.015
positive regulation of cell communication GO:0010647 271 0.015
Fly
aging GO:0007568 241 0.015
chromosome segregation GO:0007059 2 0.015
positive regulation of phosphorus metabolic process GO:0010562 262 0.015
Rat Fly
response to toxic substance GO:0009636 133 0.014
response to decreased oxygen levels GO:0036293 237 0.014
cytoplasmic transport GO:0016482 115 0.014
regulation of phosphorylation GO:0042325 248 0.014
Rat Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
growth GO:0040007 165 0.014
Fly
regulation of catalytic activity GO:0050790 304 0.014
Fly
positive regulation of cell projection organization GO:0031346 111 0.014
cellular catabolic process GO:0044248 295 0.014
peptidyl tyrosine modification GO:0018212 72 0.014
Human Rat Fly
response to other organism GO:0051707 220 0.014
response to ketone GO:1901654 182 0.014
Rat
actin filament based process GO:0030029 86 0.014
cellular lipid metabolic process GO:0044255 208 0.014
response to hexose GO:0009746 144 0.014
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.014
Rat Fly
negative regulation of cell development GO:0010721 82 0.014
regulation of anatomical structure morphogenesis GO:0022603 141 0.014
protein homotrimerization GO:0070207 15 0.014
organic substance catabolic process GO:1901575 316 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
regulation of metal ion transport GO:0010959 118 0.014
catabolic process GO:0009056 351 0.013
positive regulation of nervous system development GO:0051962 178 0.013
multicellular organism reproduction GO:0032504 233 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
hormone secretion GO:0046879 115 0.013
response to temperature stimulus GO:0009266 94 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
Rat Fly
regulation of apoptotic process GO:0042981 335 0.013
Rat
negative regulation of cell death GO:0060548 229 0.013
Rat
nucleotide metabolic process GO:0009117 279 0.013
aromatic compound catabolic process GO:0019439 168 0.013
protein oligomerization GO:0051259 191 0.013
Rat
single organism biosynthetic process GO:0044711 342 0.013
Rat
cellular divalent inorganic cation homeostasis GO:0072503 162 0.013
axon ensheathment GO:0008366 40 0.013
cellular response to alcohol GO:0097306 87 0.013
positive regulation of signaling GO:0023056 270 0.013
Fly
positive regulation of cell development GO:0010720 176 0.013
positive regulation of response to stimulus GO:0048584 285 0.013
Fly
regulation of kinase activity GO:0043549 117 0.013
Fly
eye morphogenesis GO:0048592 4 0.013
Fly
response to purine containing compound GO:0014074 126 0.013
proteolysis GO:0006508 175 0.013
nucleic acid templated transcription GO:0097659 379 0.013
chemosensory behavior GO:0007635 2 0.013
Fly
negative regulation of cell differentiation GO:0045596 99 0.013
maintenance of location GO:0051235 17 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
divalent inorganic cation homeostasis GO:0072507 165 0.013
regulation of secretion GO:0051046 224 0.013
neuron projection development GO:0031175 273 0.013
Rat Fly
response to carbohydrate GO:0009743 183 0.013
Rat
negative regulation of signal transduction GO:0009968 83 0.013
response to growth factor GO:0070848 189 0.013
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.013
axon development GO:0061564 96 0.012
Rat Fly
carboxylic acid biosynthetic process GO:0046394 83 0.012
adult locomotory behavior GO:0008344 4 0.012
negative regulation of gene expression GO:0010629 199 0.012
Rat
calcium ion homeostasis GO:0055074 162 0.012
negative regulation of nervous system development GO:0051961 79 0.012
carboxylic acid transport GO:0046942 115 0.012
negative regulation of molecular function GO:0044092 133 0.012
Rat
developmental process involved in reproduction GO:0003006 159 0.012
protein autophosphorylation GO:0046777 66 0.012
Human Rat
positive regulation of transport GO:0051050 245 0.012
response to biotic stimulus GO:0009607 226 0.012
sexual reproduction GO:0019953 148 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
Rat
regeneration GO:0031099 163 0.012
organic acid transport GO:0015849 116 0.012
regulation of multicellular organismal development GO:2000026 376 0.012
cell motility GO:0048870 202 0.012
sensory perception GO:0007600 101 0.012
cellular response to insulin stimulus GO:0032869 81 0.012
Rat
response to organophosphorus GO:0046683 102 0.012
organ regeneration GO:0031100 101 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
membrane depolarization during action potential GO:0086010 1 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
Rat
tissue development GO:0009888 252 0.012
Fly
regulation of transferase activity GO:0051338 123 0.012
Fly
anion transport GO:0006820 178 0.012
peptide secretion GO:0002790 86 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
single organism organelle organization GO:1902589 180 0.012
meiotic cell cycle process GO:1903046 3 0.012
cellular response to hormone stimulus GO:0032870 247 0.012
Rat
response to hypoxia GO:0001666 231 0.012
gland development GO:0048732 155 0.012
negative regulation of developmental process GO:0051093 125 0.012
regulation of cell proliferation GO:0042127 359 0.012
lipid storage GO:0019915 1 0.011
single organism intracellular transport GO:1902582 166 0.011
response to heat GO:0009408 60 0.011
oxidation reduction process GO:0055114 304 0.011
axis specification GO:0009798 4 0.011
synaptic transmission GO:0007268 235 0.011
Fly
regulation of ion transport GO:0043269 245 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
reproductive structure development GO:0048608 128 0.011
camera type eye development GO:0043010 48 0.011
motor neuron axon guidance GO:0008045 1 0.011
cofactor metabolic process GO:0051186 95 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
cellular cation homeostasis GO:0030003 180 0.011
circadian rhythm GO:0007623 88 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
Rat Fly
positive regulation of neuron differentiation GO:0045666 126 0.011
positive regulation of developmental process GO:0051094 283 0.011
regulation of transmembrane transport GO:0034762 122 0.011
monocarboxylic acid metabolic process GO:0032787 152 0.011
positive regulation of multicellular organismal process GO:0051240 387 0.011
heterocycle catabolic process GO:0046700 167 0.011
cellular response to growth factor stimulus GO:0071363 162 0.011
cellular hormone metabolic process GO:0034754 49 0.011
sodium ion transmembrane transport GO:0035725 67 0.011
divalent inorganic cation transport GO:0072511 134 0.011
response to reactive oxygen species GO:0000302 120 0.011
macromolecule localization GO:0033036 252 0.011
metal ion homeostasis GO:0055065 186 0.011
regulation of vesicle mediated transport GO:0060627 81 0.011
ensheathment of neurons GO:0007272 40 0.011
glial cell differentiation GO:0010001 65 0.011
regulation of cell migration GO:0030334 128 0.011
cell cycle process GO:0022402 57 0.010
Rat
response to cytokine GO:0034097 215 0.010
Rat
positive regulation of transferase activity GO:0051347 81 0.010
Fly
negative regulation of neurogenesis GO:0050768 78 0.010
response to increased oxygen levels GO:0036296 45 0.010
cellular response to peptide hormone stimulus GO:0071375 120 0.010
Rat
salivary gland development GO:0007431 3 0.010
cellular nitrogen compound catabolic process GO:0044270 163 0.010
cellular calcium ion homeostasis GO:0006874 160 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
purine nucleotide metabolic process GO:0006163 229 0.010
negative regulation of rna biosynthetic process GO:1902679 118 0.010
purine ribonucleotide catabolic process GO:0009154 136 0.010
negative regulation of cellular biosynthetic process GO:0031327 161 0.010
spindle organization GO:0007051 2 0.010
response to retinoic acid GO:0032526 63 0.010

Alk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.050
nervous system disease DOID:863 0 0.050
sensory system disease DOID:0050155 0 0.019
eye and adnexa disease DOID:1492 0 0.019
eye disease DOID:5614 0 0.019
central nervous system disease DOID:331 0 0.014
retinal disease DOID:5679 0 0.014
retinal degeneration DOID:8466 0 0.014
cone rod dystrophy DOID:0050572 0 0.014