Rattus norvegicus

0 known processes

Plk3

polo-like kinase 3 (Drosophila)

(Aliases: Cnk)

Plk3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 292 0.069
intracellular signal transduction GO:0035556 314 0.064
Mouse Rat
response to peptide hormone GO:0043434 278 0.062
regulation of nervous system development GO:0051960 264 0.061
Rat
amine metabolic process GO:0009308 38 0.059
positive regulation of multicellular organismal process GO:0051240 387 0.055
negative regulation of apoptotic process GO:0043066 181 0.052
Human
cellular response to endogenous stimulus GO:0071495 377 0.050
homeostatic process GO:0042592 331 0.046
carboxylic acid metabolic process GO:0019752 289 0.046
regulation of molecular function GO:0065009 398 0.044
Yeast Rat
regulation of neuron differentiation GO:0045664 208 0.043
Rat
negative regulation of cellular metabolic process GO:0031324 281 0.041
Human
oxoacid metabolic process GO:0043436 290 0.041
organelle organization GO:0006996 266 0.041
Human Yeast Rat
regulation of phosphorus metabolic process GO:0051174 349 0.040
positive regulation of cell proliferation GO:0008284 249 0.040
macromolecular complex subunit organization GO:0043933 339 0.039
Human Yeast
neuron differentiation GO:0030182 368 0.039
Rat
cellular amine metabolic process GO:0044106 38 0.039
regulation of neurogenesis GO:0050767 247 0.037
Rat
regulation of phosphorylation GO:0042325 248 0.037
mapk cascade GO:0000165 140 0.037
regulation of cell proliferation GO:0042127 359 0.036
regulation of cellular amine metabolic process GO:0033238 8 0.036
cellular catabolic process GO:0044248 295 0.036
Human Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.036
regulation of apoptotic process GO:0042981 335 0.036
Human
cellular response to hormone stimulus GO:0032870 247 0.035
metal ion transport GO:0030001 289 0.034
central nervous system development GO:0007417 311 0.034
regulation of multicellular organismal development GO:2000026 376 0.033
Rat
regulation of cellular amino acid metabolic process GO:0006521 2 0.033
cellular amino acid metabolic process GO:0006520 107 0.033
regulation of cell development GO:0060284 263 0.033
Rat
regulation of cell differentiation GO:0045595 320 0.032
Rat
regulation of phosphate metabolic process GO:0019220 349 0.032
neuron development GO:0048666 286 0.032
Rat
negative regulation of programmed cell death GO:0043069 183 0.031
Human
negative regulation of signaling GO:0023057 157 0.031
Rat
negative regulation of metabolic process GO:0009892 331 0.031
Human
g protein coupled receptor signaling pathway GO:0007186 242 0.031
cellular ketone metabolic process GO:0042180 51 0.030
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.030
regulation of cellular component organization GO:0051128 368 0.030
Yeast Rat
brain development GO:0007420 247 0.029
synaptic transmission GO:0007268 235 0.029
Rat
cellular component biogenesis GO:0044085 368 0.029
Yeast
regulation of catalytic activity GO:0050790 304 0.029
Yeast
programmed cell death GO:0012501 392 0.029
Human
chemical homeostasis GO:0048878 292 0.028
protein phosphorylation GO:0006468 345 0.028
Human Yeast Mouse Rat
reproductive process GO:0022414 372 0.028
cation transport GO:0006812 382 0.028
protein complex assembly GO:0006461 263 0.028
Yeast
transmembrane transport GO:0055085 412 0.028
regulation of protein modification process GO:0031399 194 0.028
positive regulation of phosphate metabolic process GO:0045937 262 0.028
multicellular organism reproduction GO:0032504 233 0.028
protein complex subunit organization GO:0071822 302 0.027
Human Yeast
carbohydrate derivative metabolic process GO:1901135 346 0.027
negative regulation of gene expression GO:0010629 199 0.027
Human
cellular cation homeostasis GO:0030003 180 0.027
divalent inorganic cation transport GO:0072511 134 0.027
circulatory system process GO:0003013 183 0.027
ion homeostasis GO:0050801 212 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
regulation of signal transduction GO:0009966 318 0.026
regulation of cellular protein metabolic process GO:0032268 267 0.026
Human Rat
positive regulation of developmental process GO:0051094 283 0.026
cellular chemical homeostasis GO:0055082 247 0.026
regulation of protein phosphorylation GO:0001932 183 0.026
apoptotic process GO:0006915 381 0.026
Human
secretion by cell GO:0032940 248 0.025
divalent metal ion transport GO:0070838 132 0.025
positive regulation of cellular component organization GO:0051130 200 0.025
Yeast
positive regulation of phosphorylation GO:0042327 177 0.025
cellular homeostasis GO:0019725 252 0.025
positive regulation of biosynthetic process GO:0009891 319 0.025
response to extracellular stimulus GO:0009991 380 0.024
single organism reproductive process GO:0044702 297 0.024
rna metabolic process GO:0016070 406 0.024
Human
macromolecular complex assembly GO:0065003 273 0.024
Yeast
response to growth factor GO:0070848 189 0.024
macromolecule localization GO:0033036 252 0.024
Human Yeast
nucleobase containing small molecule metabolic process GO:0055086 316 0.024
negative regulation of cell death GO:0060548 229 0.023
Human
regulation of cell projection organization GO:0031344 175 0.023
Rat
positive regulation of cell differentiation GO:0045597 217 0.023
response to peptide GO:1901652 292 0.023
cellular component movement GO:0006928 248 0.023
response to estrogen GO:0043627 232 0.022
rhythmic process GO:0048511 156 0.022
anion transport GO:0006820 178 0.022
anatomical structure morphogenesis GO:0009653 298 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
signal transduction by phosphorylation GO:0023014 144 0.022
ion transmembrane transport GO:0034220 365 0.022
regulation of transferase activity GO:0051338 123 0.022
organic substance catabolic process GO:1901575 316 0.022
Human Rat
response to inorganic substance GO:0010035 377 0.022
single organism catabolic process GO:0044712 283 0.021
cation transmembrane transport GO:0098655 263 0.021
multi organism reproductive process GO:0044703 262 0.021
organic anion transport GO:0015711 132 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.021
Human
positive regulation of protein metabolic process GO:0051247 178 0.021
Human Rat
regulation of neuron projection development GO:0010975 161 0.021
Rat
positive regulation of nervous system development GO:0051962 178 0.021
regulation of protein metabolic process GO:0051246 289 0.021
Human Rat
regulation of cellular component movement GO:0051270 150 0.021
neuron projection development GO:0031175 273 0.021
Rat
response to metal ion GO:0010038 253 0.020
secretion GO:0046903 307 0.020
regulation of secretion by cell GO:1903530 208 0.020
calcium ion transport GO:0006816 131 0.020
rna biosynthetic process GO:0032774 380 0.020
Human
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
cellular response to oxygen containing compound GO:1901701 386 0.020
response to nutrient levels GO:0031667 370 0.020
organophosphate metabolic process GO:0019637 370 0.020
transcription from rna polymerase ii promoter GO:0006366 252 0.020
Human
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
positive regulation of signaling GO:0023056 270 0.019
Rat
regulation of cellular localization GO:0060341 263 0.019
Human
positive regulation of cell development GO:0010720 176 0.019
transcription dna templated GO:0006351 377 0.019
Human
locomotion GO:0040011 237 0.019
regulation of programmed cell death GO:0043067 341 0.019
Human
cellular ion homeostasis GO:0006873 184 0.018
catabolic process GO:0009056 351 0.018
Human Rat
nucleoside phosphate metabolic process GO:0006753 283 0.018
response to acid chemical GO:0001101 222 0.018
negative regulation of cell communication GO:0010648 158 0.018
Rat
negative regulation of macromolecule metabolic process GO:0010605 260 0.018
Human
cellular component assembly GO:0022607 360 0.018
Yeast
negative regulation of transport GO:0051051 136 0.018
response to purine containing compound GO:0014074 126 0.018
multi multicellular organism process GO:0044706 138 0.018
regulation of ion transport GO:0043269 245 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
establishment of protein localization GO:0045184 141 0.018
Human
cell migration GO:0016477 197 0.018
cellular response to organonitrogen compound GO:0071417 197 0.018
cardiovascular system development GO:0072358 134 0.018
regulation of hormone levels GO:0010817 187 0.018
intracellular transport GO:0046907 185 0.017
Human
carboxylic acid transport GO:0046942 115 0.017
regulation of kinase activity GO:0043549 117 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
nucleoside metabolic process GO:0009116 179 0.017
positive regulation of cell projection organization GO:0031346 111 0.017
positive regulation of response to stimulus GO:0048584 285 0.017
response to oxidative stress GO:0006979 186 0.017
Human
oxidation reduction process GO:0055114 304 0.017
response to hexose GO:0009746 144 0.017
response to ethanol GO:0045471 162 0.017
single organism biosynthetic process GO:0044711 342 0.017
single organism intracellular transport GO:1902582 166 0.017
multicellular organismal reproductive process GO:0048609 233 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
Human
glycosyl compound metabolic process GO:1901657 182 0.017
localization of cell GO:0051674 202 0.017
negative regulation of protein metabolic process GO:0051248 114 0.017
cellular response to nitrogen compound GO:1901699 210 0.017
response to alkaloid GO:0043279 132 0.016
regulation of rna biosynthetic process GO:2001141 381 0.016
Human
regulation of system process GO:0044057 208 0.016
circulatory system development GO:0072359 134 0.016
regulation of synaptic transmission GO:0050804 141 0.016
Rat
positive regulation of cell communication GO:0010647 271 0.016
Rat
cellular response to stress GO:0033554 269 0.016
Human Mouse
cellular response to organic cyclic compound GO:0071407 202 0.016
protein localization GO:0008104 191 0.016
Human Yeast
protein complex biogenesis GO:0070271 263 0.016
Yeast
positive regulation of catalytic activity GO:0043085 184 0.016
Yeast
regulation of rna metabolic process GO:0051252 391 0.016
Human
heterocycle catabolic process GO:0046700 167 0.016
regulation of protein kinase activity GO:0045859 105 0.016
response to hypoxia GO:0001666 231 0.016
Human
negative regulation of neurogenesis GO:0050768 78 0.015
Rat
purine ribonucleoside metabolic process GO:0046128 168 0.015
purine containing compound metabolic process GO:0072521 253 0.015
peptidyl amino acid modification GO:0018193 126 0.015
cellular protein localization GO:0034613 122 0.015
Human
positive regulation of neurogenesis GO:0050769 165 0.015
cellular response to peptide GO:1901653 133 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.015
inorganic ion transmembrane transport GO:0098660 229 0.015
cell cell signaling GO:0007267 335 0.015
Rat
cell motility GO:0048870 202 0.015
hormone secretion GO:0046879 115 0.015
regulation of mapk cascade GO:0043408 116 0.015
organic acid transport GO:0015849 116 0.015
response to ammonium ion GO:0060359 71 0.015
growth GO:0040007 165 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
Human Rat
nucleotide metabolic process GO:0009117 279 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
Human
response to glucocorticoid GO:0051384 223 0.014
nitrogen compound transport GO:0071705 229 0.014
lipid biosynthetic process GO:0008610 128 0.014
positive regulation of mapk cascade GO:0043410 92 0.014
protein transport GO:0015031 132 0.014
Human
anterior posterior pattern specification GO:0009952 1 0.014
negative regulation of molecular function GO:0044092 133 0.014
gastrulation GO:0007369 2 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
response to nutrient GO:0007584 248 0.014
behavior GO:0007610 205 0.014
positive regulation of cell death GO:0010942 184 0.014
regulation of hormone secretion GO:0046883 106 0.014
cell projection organization GO:0030030 302 0.014
Rat
ras protein signal transduction GO:0007265 29 0.014
Rat
cell morphogenesis GO:0000902 142 0.014
neuron death GO:0070997 127 0.014
metal ion homeostasis GO:0055065 186 0.014
cellular macromolecule localization GO:0070727 122 0.014
Human
ribonucleoside catabolic process GO:0042454 126 0.014
nucleic acid templated transcription GO:0097659 379 0.014
Human
purine ribonucleotide metabolic process GO:0009150 227 0.014
neuron projection morphogenesis GO:0048812 122 0.014
cation homeostasis GO:0055080 195 0.014
blood circulation GO:0008015 183 0.014
muscle system process GO:0003012 115 0.014
regulation of proteasomal protein catabolic process GO:0061136 4 0.013
Human Rat
regulation of membrane potential GO:0042391 110 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
calcium ion homeostasis GO:0055074 162 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.013
developmental process involved in reproduction GO:0003006 159 0.013
positive regulation of transport GO:0051050 245 0.013
Human
response to monosaccharide GO:0034284 159 0.013
blood vessel development GO:0001568 69 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
regulation of anatomical structure morphogenesis GO:0022603 141 0.013
embryonic pattern specification GO:0009880 1 0.013
response to transition metal nanoparticle GO:1990267 122 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
response to glucose GO:0009749 136 0.013
reactive nitrogen species metabolic process GO:2001057 1 0.013
development of primary sexual characteristics GO:0045137 107 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
regeneration GO:0031099 163 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
amide transport GO:0042886 105 0.013
response to toxic substance GO:0009636 133 0.013
Rat
reproduction GO:0000003 245 0.013
Yeast Rat
signal release GO:0023061 145 0.013
organic cyclic compound catabolic process GO:1901361 175 0.012
regulation of synaptic plasticity GO:0048167 70 0.012
Rat
nucleobase containing compound catabolic process GO:0034655 152 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.012
cellular calcium ion homeostasis GO:0006874 160 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
regulation of nucleic acid templated transcription GO:1903506 380 0.012
Human
response to ketone GO:1901654 182 0.012
aromatic compound catabolic process GO:0019439 168 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
positive regulation of gene expression GO:0010628 244 0.012
regulation of blood pressure GO:0008217 83 0.012
response to carbohydrate GO:0009743 183 0.012
proteolysis GO:0006508 175 0.012
Human Rat
regulation of homeostatic process GO:0032844 101 0.012
single organism membrane organization GO:0044802 74 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
regulation of blood circulation GO:1903522 110 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
Human
regulation of cell migration GO:0030334 128 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
head development GO:0060322 247 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
positive regulation of transferase activity GO:0051347 81 0.011
response to reactive oxygen species GO:0000302 120 0.011
Human
regulation of heart contraction GO:0008016 48 0.011
cellular component morphogenesis GO:0032989 155 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
positive regulation of protein modification process GO:0031401 142 0.011
peptide hormone secretion GO:0030072 84 0.011
peptide secretion GO:0002790 86 0.011
neurological system process GO:0050877 219 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
adult locomotory behavior GO:0008344 4 0.011
cytoplasmic transport GO:0016482 115 0.011
negative regulation of phosphate metabolic process GO:0045936 80 0.011
sexual reproduction GO:0019953 148 0.011
axis specification GO:0009798 4 0.011
response to oxygen levels GO:0070482 265 0.011
Human
reactive oxygen species metabolic process GO:0072593 37 0.011
response to decreased oxygen levels GO:0036293 237 0.011
Human
inorganic cation transmembrane transport GO:0098662 202 0.011
single organism organelle organization GO:1902589 180 0.011
Human Yeast
small gtpase mediated signal transduction GO:0007264 36 0.011
Rat
formation of primary germ layer GO:0001704 1 0.011
cell growth GO:0016049 104 0.011
positive regulation of signal transduction GO:0009967 175 0.011
purine containing compound catabolic process GO:0072523 138 0.010
negative regulation of response to stimulus GO:0048585 155 0.010
cellular divalent inorganic cation homeostasis GO:0072503 162 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.010
Human
ribonucleoside triphosphate metabolic process GO:0009199 141 0.010
negative regulation of protein phosphorylation GO:0001933 44 0.010
protein oligomerization GO:0051259 191 0.010
positive regulation of rna biosynthetic process GO:1902680 197 0.010
vesicle mediated transport GO:0016192 181 0.010
positive regulation of molecular function GO:0044093 230 0.010
Yeast Rat
regulation of fat cell differentiation GO:0045598 3 0.010
carbohydrate metabolic process GO:0005975 130 0.010
positive regulation of rna metabolic process GO:0051254 203 0.010
multicellular organism growth GO:0035264 1 0.010
ribonucleoside metabolic process GO:0009119 174 0.010
regulation of smooth muscle cell proliferation GO:0048660 75 0.010
positive regulation of secretion GO:0051047 140 0.010
regulation of cell motility GO:2000145 131 0.010
negative regulation of hormone secretion GO:0046888 46 0.010
membrane organization GO:0061024 94 0.010

Plk3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
central nervous system disease DOID:331 0 0.013
disease of metabolism DOID:0014667 0 0.011
disease of cellular proliferation DOID:14566 0 0.010