Rattus norvegicus

0 known processes

Ocrl

oculocerebrorenal syndrome of Lowe

Ocrl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of phosphorus metabolic process GO:0010562 262 0.049
Human
neuron development GO:0048666 286 0.046
regulation of signal transduction GO:0009966 318 0.045
Human
positive regulation of multicellular organismal process GO:0051240 387 0.045
oxoacid metabolic process GO:0043436 290 0.043
nucleobase containing small molecule metabolic process GO:0055086 316 0.042
Human
rna metabolic process GO:0016070 406 0.042
regulation of phosphorus metabolic process GO:0051174 349 0.042
Human
neuron differentiation GO:0030182 368 0.041
regulation of apoptotic process GO:0042981 335 0.041
intracellular signal transduction GO:0035556 314 0.040
organic acid metabolic process GO:0006082 292 0.039
positive regulation of phosphate metabolic process GO:0045937 262 0.038
Human
cellular response to endogenous stimulus GO:0071495 377 0.037
purine nucleotide metabolic process GO:0006163 229 0.037
Human
regulation of molecular function GO:0065009 398 0.037
Human
transcription dna templated GO:0006351 377 0.037
cellular response to oxygen containing compound GO:1901701 386 0.036
catabolic process GO:0009056 351 0.036
Human
positive regulation of response to stimulus GO:0048584 285 0.036
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.035
Human
carbohydrate derivative metabolic process GO:1901135 346 0.035
Human
apoptotic process GO:0006915 381 0.035
response to nutrient levels GO:0031667 370 0.035
nucleic acid templated transcription GO:0097659 379 0.034
glycosyl compound metabolic process GO:1901657 182 0.034
Human
organic substance catabolic process GO:1901575 316 0.034
Human
positive regulation of neurogenesis GO:0050769 165 0.033
response to extracellular stimulus GO:0009991 380 0.033
neuron projection development GO:0031175 273 0.033
purine containing compound metabolic process GO:0072521 253 0.032
Human
rna biosynthetic process GO:0032774 380 0.032
positive regulation of neuron projection development GO:0010976 99 0.032
protein complex assembly GO:0006461 263 0.032
nitrogen compound transport GO:0071705 229 0.031
regulation of transcription dna templated GO:0006355 374 0.031
positive regulation of nervous system development GO:0051962 178 0.031
regulation of cell proliferation GO:0042127 359 0.030
cellular component biogenesis GO:0044085 368 0.030
Human Fly
positive regulation of cell differentiation GO:0045597 217 0.030
regulation of nucleic acid templated transcription GO:1903506 380 0.030
nucleoside phosphate metabolic process GO:0006753 283 0.030
Human
carboxylic acid metabolic process GO:0019752 289 0.030
regulation of rna biosynthetic process GO:2001141 381 0.029
programmed cell death GO:0012501 392 0.029
central nervous system development GO:0007417 311 0.029
single organism intracellular transport GO:1902582 166 0.029
cell projection organization GO:0030030 302 0.029
Human
regulation of nervous system development GO:0051960 264 0.029
regulation of neuron differentiation GO:0045664 208 0.029
organophosphate metabolic process GO:0019637 370 0.029
Human Fly
cellular response to stress GO:0033554 269 0.028
intracellular transport GO:0046907 185 0.028
small gtpase mediated signal transduction GO:0007264 36 0.028
regulation of cell projection organization GO:0031344 175 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
ribose phosphate metabolic process GO:0019693 235 0.027
Human
cellular component assembly GO:0022607 360 0.026
Human Fly
purine nucleoside triphosphate catabolic process GO:0009146 122 0.026
Human
regulation of cellular amine metabolic process GO:0033238 8 0.026
positive regulation of cellular protein metabolic process GO:0032270 167 0.026
positive regulation of cell proliferation GO:0008284 249 0.026
nucleotide catabolic process GO:0009166 139 0.026
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.026
Human
positive regulation of cellular component organization GO:0051130 200 0.025
response to metal ion GO:0010038 253 0.025
ras protein signal transduction GO:0007265 29 0.025
nucleotide metabolic process GO:0009117 279 0.025
Human
carbohydrate derivative catabolic process GO:1901136 147 0.025
Human
ribonucleotide catabolic process GO:0009261 136 0.024
Human
cellular catabolic process GO:0044248 295 0.024
Human
synaptic transmission GO:0007268 235 0.024
cellular response to nitrogen compound GO:1901699 210 0.024
transmembrane transport GO:0055085 412 0.024
positive regulation of protein modification process GO:0031401 142 0.024
locomotion GO:0040011 237 0.024
regulation of phosphorylation GO:0042325 248 0.024
regulation of cellular component organization GO:0051128 368 0.024
Fly
g protein coupled receptor signaling pathway GO:0007186 242 0.024
regulation of phosphate metabolic process GO:0019220 349 0.024
Human
single organism catabolic process GO:0044712 283 0.024
Human
cellular component movement GO:0006928 248 0.024
lipid metabolic process GO:0006629 283 0.023
Fly
head development GO:0060322 247 0.023
macromolecule localization GO:0033036 252 0.023
cellular amine metabolic process GO:0044106 38 0.023
regulation of cell development GO:0060284 263 0.023
nucleoside phosphate catabolic process GO:1901292 140 0.023
Human
brain development GO:0007420 247 0.023
response to inorganic substance GO:0010035 377 0.023
organic cyclic compound catabolic process GO:1901361 175 0.023
Human
positive regulation of cell projection organization GO:0031346 111 0.023
single organism biosynthetic process GO:0044711 342 0.023
positive regulation of catalytic activity GO:0043085 184 0.023
Human
positive regulation of cellular biosynthetic process GO:0031328 295 0.023
positive regulation of developmental process GO:0051094 283 0.023
anatomical structure morphogenesis GO:0009653 298 0.023
Human
positive regulation of protein metabolic process GO:0051247 178 0.023
regulation of cellular localization GO:0060341 263 0.023
amine metabolic process GO:0009308 38 0.023
regulation of neuron projection development GO:0010975 161 0.023
regulation of catalytic activity GO:0050790 304 0.023
Human
negative regulation of cell communication GO:0010648 158 0.022
purine ribonucleoside metabolic process GO:0046128 168 0.022
Human
cellular amino acid metabolic process GO:0006520 107 0.022
regulation of anatomical structure size GO:0090066 135 0.022
positive regulation of cell communication GO:0010647 271 0.022
positive regulation of neuron differentiation GO:0045666 126 0.022
organonitrogen compound catabolic process GO:1901565 179 0.022
Human
purine nucleoside catabolic process GO:0006152 124 0.022
Human
reproductive process GO:0022414 372 0.022
nucleobase containing compound catabolic process GO:0034655 152 0.022
Human
regulation of cellular ketone metabolic process GO:0010565 27 0.022
purine nucleoside triphosphate metabolic process GO:0009144 141 0.022
Human
regulation of purine nucleotide metabolic process GO:1900542 115 0.022
Human
purine ribonucleotide metabolic process GO:0009150 227 0.022
Human
regulation of locomotion GO:0040012 148 0.021
protein phosphorylation GO:0006468 345 0.021
protein complex biogenesis GO:0070271 263 0.021
protein complex subunit organization GO:0071822 302 0.021
negative regulation of cell death GO:0060548 229 0.021
reproduction GO:0000003 245 0.021
positive regulation of cell development GO:0010720 176 0.021
ribonucleotide metabolic process GO:0009259 231 0.021
Human
multicellular organismal reproductive process GO:0048609 233 0.021
positive regulation of biosynthetic process GO:0009891 319 0.021
nucleoside triphosphate metabolic process GO:0009141 144 0.021
Human
cell cell signaling GO:0007267 335 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.020
Human
positive regulation of phosphorylation GO:0042327 177 0.020
ion transmembrane transport GO:0034220 365 0.020
cation transport GO:0006812 382 0.020
regulation of neurogenesis GO:0050767 247 0.020
regulation of synaptic transmission GO:0050804 141 0.020
cell morphogenesis GO:0000902 142 0.020
Human
multi organism reproductive process GO:0044703 262 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
regulation of protein metabolic process GO:0051246 289 0.020
macromolecular complex assembly GO:0065003 273 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
chromosome segregation GO:0007059 2 0.020
regulation of programmed cell death GO:0043067 341 0.019
regulation of protein phosphorylation GO:0001932 183 0.019
multicellular organism reproduction GO:0032504 233 0.019
cell migration GO:0016477 197 0.019
aging GO:0007568 241 0.019
response to growth factor GO:0070848 189 0.019
cellular ketone metabolic process GO:0042180 51 0.019
nucleoside catabolic process GO:0009164 126 0.019
Human
purine nucleotide catabolic process GO:0006195 136 0.018
Human
regulation of multicellular organismal development GO:2000026 376 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
Human
negative regulation of metabolic process GO:0009892 331 0.018
gtp catabolic process GO:0006184 71 0.018
Human
heterocycle catabolic process GO:0046700 167 0.018
Human
macromolecular complex subunit organization GO:0043933 339 0.018
cellular response to hormone stimulus GO:0032870 247 0.018
regulation of catabolic process GO:0009894 113 0.018
Human
protein oligomerization GO:0051259 191 0.018
response to wounding GO:0009611 254 0.018
purine ribonucleoside catabolic process GO:0046130 124 0.018
Human
response to oxygen levels GO:0070482 265 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.017
regulation of cell differentiation GO:0045595 320 0.017
synaptic growth at neuromuscular junction GO:0051124 1 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.017
secretion GO:0046903 307 0.017
neuron death GO:0070997 127 0.017
ribonucleoside triphosphate metabolic process GO:0009199 141 0.017
Human
regulation of membrane potential GO:0042391 110 0.017
organophosphate catabolic process GO:0046434 148 0.017
Human
regulation of nucleotide metabolic process GO:0006140 117 0.017
Human
regulation of kinase activity GO:0043549 117 0.017
immune response GO:0006955 104 0.017
signal transduction by phosphorylation GO:0023014 144 0.017
response to peptide hormone GO:0043434 278 0.017
ribonucleoside metabolic process GO:0009119 174 0.017
Human
growth GO:0040007 165 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
cellular homeostasis GO:0019725 252 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
positive regulation of rna metabolic process GO:0051254 203 0.016
regulation of cellular component movement GO:0051270 150 0.016
localization of cell GO:0051674 202 0.016
response to decreased oxygen levels GO:0036293 237 0.016
negative regulation of cell proliferation GO:0008285 119 0.016
response to acid chemical GO:0001101 222 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
Human
cell part morphogenesis GO:0032990 123 0.016
Human
regulation of cell morphogenesis GO:0022604 77 0.016
organophosphate biosynthetic process GO:0090407 143 0.016
guanosine containing compound catabolic process GO:1901069 71 0.016
Human
single organism reproductive process GO:0044702 297 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
positive regulation of cell death GO:0010942 184 0.016
cellular response to lipid GO:0071396 201 0.016
rho protein signal transduction GO:0007266 11 0.016
cellular lipid metabolic process GO:0044255 208 0.016
Fly
vesicle mediated transport GO:0016192 181 0.015
Fly
regulation of transferase activity GO:0051338 123 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
positive regulation of molecular function GO:0044093 230 0.015
Human
ion homeostasis GO:0050801 212 0.015
chemical homeostasis GO:0048878 292 0.015
negative regulation of transport GO:0051051 136 0.015
response to hypoxia GO:0001666 231 0.015
defense response GO:0006952 194 0.015
regulation of response to stress GO:0080134 126 0.015
cellular calcium ion homeostasis GO:0006874 160 0.015
cation homeostasis GO:0055080 195 0.015
divalent inorganic cation homeostasis GO:0072507 165 0.015
nucleoside triphosphate catabolic process GO:0009143 123 0.015
Human
regulation of protein modification process GO:0031399 194 0.015
neurological system process GO:0050877 219 0.015
response to nutrient GO:0007584 248 0.015
positive regulation of nucleotide metabolic process GO:0045981 91 0.015
Human
negative regulation of macromolecule metabolic process GO:0010605 260 0.015
aromatic compound catabolic process GO:0019439 168 0.015
Human
calcium ion homeostasis GO:0055074 162 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.015
Human
cell morphogenesis involved in differentiation GO:0000904 119 0.015
cell adhesion GO:0007155 110 0.015
ribonucleoside triphosphate catabolic process GO:0009203 122 0.014
Human
metal ion transport GO:0030001 289 0.014
negative regulation of signaling GO:0023057 157 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.014
adult locomotory behavior GO:0008344 4 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
regulation of anatomical structure morphogenesis GO:0022603 141 0.014
neuron projection morphogenesis GO:0048812 122 0.014
regulation of cell migration GO:0030334 128 0.014
rhythmic process GO:0048511 156 0.014
negative regulation of gene expression GO:0010629 199 0.014
regulation of neuron death GO:1901214 115 0.014
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
cellular chemical homeostasis GO:0055082 247 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
regulation of response to external stimulus GO:0032101 106 0.014
transcription from rna polymerase ii promoter GO:0006366 252 0.014
negative regulation of nucleic acid templated transcription GO:1903507 117 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
gastrulation GO:0007369 2 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
regulation of rna metabolic process GO:0051252 391 0.014
actin cytoskeleton organization GO:0030036 73 0.014
Fly
response to lipopolysaccharide GO:0032496 191 0.014
positive regulation of signal transduction GO:0009967 175 0.014
multicellular organism growth GO:0035264 1 0.014
negative regulation of response to stimulus GO:0048585 155 0.013
cytoplasmic transport GO:0016482 115 0.013
response to ketone GO:1901654 182 0.013
response to alkaloid GO:0043279 132 0.013
inflammatory response GO:0006954 150 0.013
regulation of secretion GO:0051046 224 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
dendrite development GO:0016358 72 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
Human
mapk cascade GO:0000165 140 0.013
regulation of hydrolase activity GO:0051336 143 0.013
Human
cellular ion homeostasis GO:0006873 184 0.013
cell motility GO:0048870 202 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
Human
cytosolic calcium ion homeostasis GO:0051480 140 0.013
blood circulation GO:0008015 183 0.013
metal ion homeostasis GO:0055065 186 0.013
regulation of small gtpase mediated signal transduction GO:0051056 48 0.013
Human
nucleoside metabolic process GO:0009116 179 0.013
Human
positive regulation of gene expression GO:0010628 244 0.013
response to corticosteroid GO:0031960 235 0.012
positive regulation of cellular catabolic process GO:0031331 71 0.012
Human
regulation of dendrite development GO:0050773 59 0.012
positive regulation of cellular component movement GO:0051272 102 0.012
purine containing compound catabolic process GO:0072523 138 0.012
Human
anion transport GO:0006820 178 0.012
cellular cation homeostasis GO:0030003 180 0.012
sexual reproduction GO:0019953 148 0.012
regulation of cell growth GO:0001558 85 0.012
negative regulation of cellular metabolic process GO:0031324 281 0.012
cell growth GO:0016049 104 0.012
mitotic sister chromatid segregation GO:0000070 1 0.012
positive regulation of locomotion GO:0040017 102 0.012
lipid biosynthetic process GO:0008610 128 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
Human
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.012
actin filament based process GO:0030029 86 0.012
Fly
regulation of cell motility GO:2000145 131 0.012
positive regulation of transferase activity GO:0051347 81 0.012
hormone secretion GO:0046879 115 0.012
regeneration GO:0031099 163 0.012
positive regulation of signaling GO:0023056 270 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
Human
homeostatic process GO:0042592 331 0.012
cell type specific apoptotic process GO:0097285 134 0.012
regulation of gtpase activity GO:0043087 57 0.011
Human
organelle organization GO:0006996 266 0.011
Human Fly
oxidation reduction process GO:0055114 304 0.011
cellular protein localization GO:0034613 122 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
regulation of gtp catabolic process GO:0033124 58 0.011
Human
secretion by cell GO:0032940 248 0.011
circulatory system process GO:0003013 183 0.011
ovulation cycle GO:0042698 67 0.011
tissue development GO:0009888 252 0.011
response to ethanol GO:0045471 162 0.011
transmission of nerve impulse GO:0019226 42 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
response to reactive oxygen species GO:0000302 120 0.011
carboxylic acid transport GO:0046942 115 0.011
axon development GO:0061564 96 0.011
response to insulin GO:0032868 133 0.011
regulation of mapk cascade GO:0043408 116 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
regulation of system process GO:0044057 208 0.011
gtp metabolic process GO:0046039 72 0.010
Human
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
response to glucocorticoid GO:0051384 223 0.010
multi multicellular organism process GO:0044706 138 0.010
single organism organelle organization GO:1902589 180 0.010
Human Fly
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.010
Human
positive regulation of transcription dna templated GO:0045893 197 0.010
response to peptide GO:1901652 292 0.010
neuronal action potential GO:0019228 35 0.010
regulation of neuron apoptotic process GO:0043523 83 0.010
gamete generation GO:0007276 124 0.010
cellular component morphogenesis GO:0032989 155 0.010
Human
response to estrogen GO:0043627 232 0.010
positive regulation of nucleoside metabolic process GO:0045979 55 0.010
Human
negative regulation of rna biosynthetic process GO:1902679 118 0.010
behavior GO:0007610 205 0.010
regulation of cellular catabolic process GO:0031329 101 0.010
Human
positive regulation of transport GO:0051050 245 0.010

Ocrl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.030
disease of cellular proliferation DOID:14566 0 0.015
central nervous system disease DOID:331 0 0.014
cancer DOID:162 0 0.011