Rattus norvegicus

0 known processes

Sptlc3

serine palmitoyltransferase, long chain base subunit 3

(Aliases: RGD1310030)

Sptlc3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
programmed cell death GO:0012501 392 0.044
nucleic acid templated transcription GO:0097659 379 0.042
rna metabolic process GO:0016070 406 0.040
apoptotic process GO:0006915 381 0.040
rna biosynthetic process GO:0032774 380 0.039
regulation of rna biosynthetic process GO:2001141 381 0.039
regulation of transcription dna templated GO:0006355 374 0.037
regulation of rna metabolic process GO:0051252 391 0.037
transcription dna templated GO:0006351 377 0.036
regulation of cell proliferation GO:0042127 359 0.036
reproductive process GO:0022414 372 0.036
regulation of programmed cell death GO:0043067 341 0.036
regulation of cell differentiation GO:0045595 320 0.035
cation transport GO:0006812 382 0.034
negative regulation of metabolic process GO:0009892 331 0.034
regulation of nucleic acid templated transcription GO:1903506 380 0.034
regulation of multicellular organismal development GO:2000026 376 0.033
secretion GO:0046903 307 0.033
homeostatic process GO:0042592 331 0.032
regulation of secretion GO:0051046 224 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.032
neuron differentiation GO:0030182 368 0.032
transcription from rna polymerase ii promoter GO:0006366 252 0.030
response to inorganic substance GO:0010035 377 0.030
carbohydrate derivative metabolic process GO:1901135 346 0.030
response to extracellular stimulus GO:0009991 380 0.030
positive regulation of cellular biosynthetic process GO:0031328 295 0.029
oxoacid metabolic process GO:0043436 290 0.029
cellular component assembly GO:0022607 360 0.029
positive regulation of multicellular organismal process GO:0051240 387 0.029
positive regulation of biosynthetic process GO:0009891 319 0.029
organic acid metabolic process GO:0006082 292 0.029
multi organism reproductive process GO:0044703 262 0.029
carboxylic acid metabolic process GO:0019752 289 0.029
cellular response to oxygen containing compound GO:1901701 386 0.029
single organism reproductive process GO:0044702 297 0.028
regulation of molecular function GO:0065009 398 0.028
cellular amino acid metabolic process GO:0006520 107 0.027
cellular component biogenesis GO:0044085 368 0.027
negative regulation of macromolecule metabolic process GO:0010605 260 0.027
negative regulation of cellular metabolic process GO:0031324 281 0.027
response to nutrient levels GO:0031667 370 0.027
regulation of nervous system development GO:0051960 264 0.027
nucleobase containing small molecule metabolic process GO:0055086 316 0.027
regulation of apoptotic process GO:0042981 335 0.026
cellular amine metabolic process GO:0044106 38 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.026
regulation of phosphorus metabolic process GO:0051174 349 0.026
regulation of secretion by cell GO:1903530 208 0.026
reproduction GO:0000003 245 0.026
cellular ketone metabolic process GO:0042180 51 0.026
regulation of hormone levels GO:0010817 187 0.025
intracellular signal transduction GO:0035556 314 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.025
cell cell signaling GO:0007267 335 0.025
catabolic process GO:0009056 351 0.025
secretion by cell GO:0032940 248 0.025
regulation of cellular component organization GO:0051128 368 0.025
regulation of phosphate metabolic process GO:0019220 349 0.025
chemical homeostasis GO:0048878 292 0.025
multicellular organism reproduction GO:0032504 233 0.025
macromolecular complex assembly GO:0065003 273 0.025
metal ion transport GO:0030001 289 0.025
nitrogen compound transport GO:0071705 229 0.025
organophosphate metabolic process GO:0019637 370 0.025
regulation of neurogenesis GO:0050767 247 0.025
regulation of cellular localization GO:0060341 263 0.024
amine metabolic process GO:0009308 38 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
organic substance catabolic process GO:1901575 316 0.024
protein complex subunit organization GO:0071822 302 0.024
cellular response to stress GO:0033554 269 0.024
cell projection organization GO:0030030 302 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
regulation of cellular amine metabolic process GO:0033238 8 0.024
central nervous system development GO:0007417 311 0.024
nucleoside phosphate metabolic process GO:0006753 283 0.024
positive regulation of cell proliferation GO:0008284 249 0.024
negative regulation of gene expression GO:0010629 199 0.024
regulation of signal transduction GO:0009966 318 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.023
negative regulation of cell death GO:0060548 229 0.023
regulation of cell development GO:0060284 263 0.023
regulation of phosphorylation GO:0042325 248 0.023
positive regulation of gene expression GO:0010628 244 0.023
regulation of protein metabolic process GO:0051246 289 0.023
ion transmembrane transport GO:0034220 365 0.023
response to wounding GO:0009611 254 0.023
nucleotide metabolic process GO:0009117 279 0.023
positive regulation of developmental process GO:0051094 283 0.023
protein complex biogenesis GO:0070271 263 0.023
cellular catabolic process GO:0044248 295 0.023
head development GO:0060322 247 0.023
purine containing compound metabolic process GO:0072521 253 0.022
response to metal ion GO:0010038 253 0.022
positive regulation of cell differentiation GO:0045597 217 0.022
response to hypoxia GO:0001666 231 0.022
g protein coupled receptor signaling pathway GO:0007186 242 0.022
neuron projection development GO:0031175 273 0.022
response to oxygen levels GO:0070482 265 0.022
neuron development GO:0048666 286 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.021
negative regulation of programmed cell death GO:0043069 183 0.021
tissue development GO:0009888 252 0.021
positive regulation of phosphate metabolic process GO:0045937 262 0.021
brain development GO:0007420 247 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
cellular response to endogenous stimulus GO:0071495 377 0.021
response to peptide GO:1901652 292 0.021
positive regulation of signaling GO:0023056 270 0.021
regulation of cellular protein metabolic process GO:0032268 267 0.021
cellular homeostasis GO:0019725 252 0.021
macromolecular complex subunit organization GO:0043933 339 0.021
cellular response to nitrogen compound GO:1901699 210 0.020
protein phosphorylation GO:0006468 345 0.020
ribonucleotide metabolic process GO:0009259 231 0.020
locomotion GO:0040011 237 0.020
transmembrane transport GO:0055085 412 0.020
positive regulation of transport GO:0051050 245 0.020
regulation of neuron differentiation GO:0045664 208 0.020
regulation of catalytic activity GO:0050790 304 0.020
protein oligomerization GO:0051259 191 0.020
defense response GO:0006952 194 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.019
positive regulation of rna metabolic process GO:0051254 203 0.019
response to cytokine GO:0034097 215 0.019
positive regulation of phosphorus metabolic process GO:0010562 262 0.019
protein complex assembly GO:0006461 263 0.019
positive regulation of response to stimulus GO:0048584 285 0.019
response to peptide hormone GO:0043434 278 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
response to decreased oxygen levels GO:0036293 237 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
negative regulation of biosynthetic process GO:0009890 168 0.019
positive regulation of secretion GO:0051047 140 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
positive regulation of cell communication GO:0010647 271 0.019
regulation of intracellular signal transduction GO:1902531 218 0.018
organonitrogen compound catabolic process GO:1901565 179 0.018
response to growth factor GO:0070848 189 0.018
signal release GO:0023061 145 0.018
cation transmembrane transport GO:0098655 263 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.018
positive regulation of molecular function GO:0044093 230 0.018
negative regulation of cellular biosynthetic process GO:0031327 161 0.018
aging GO:0007568 241 0.018
single organism biosynthetic process GO:0044711 342 0.018
Human
localization of cell GO:0051674 202 0.018
response to external biotic stimulus GO:0043207 221 0.018
negative regulation of transport GO:0051051 136 0.018
cellular chemical homeostasis GO:0055082 247 0.018
anterior posterior pattern specification GO:0009952 1 0.018
negative regulation of signaling GO:0023057 157 0.018
synaptic transmission GO:0007268 235 0.018
cellular component movement GO:0006928 248 0.017
negative regulation of multicellular organismal process GO:0051241 203 0.017
hormone secretion GO:0046879 115 0.017
cation homeostasis GO:0055080 195 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
cellular response to hormone stimulus GO:0032870 247 0.017
cellular response to lipid GO:0071396 201 0.017
hormone transport GO:0009914 121 0.017
positive regulation of cell death GO:0010942 184 0.017
cell migration GO:0016477 197 0.017
positive regulation of secretion by cell GO:1903532 128 0.017
metal ion homeostasis GO:0055065 186 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
response to glucose GO:0009749 136 0.017
single organism catabolic process GO:0044712 283 0.017
lipid metabolic process GO:0006629 283 0.017
Human
response to molecule of bacterial origin GO:0002237 194 0.017
anion transport GO:0006820 178 0.017
positive regulation of phosphorylation GO:0042327 177 0.017
regulation of system process GO:0044057 208 0.017
response to corticosteroid GO:0031960 235 0.017
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.017
cellular ion homeostasis GO:0006873 184 0.017
calcium ion homeostasis GO:0055074 162 0.017
ion homeostasis GO:0050801 212 0.017
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
sexual reproduction GO:0019953 148 0.017
cell motility GO:0048870 202 0.016
regulation of ion transport GO:0043269 245 0.016
immune system process GO:0002376 204 0.016
response to ethanol GO:0045471 162 0.016
regulation of neuron projection development GO:0010975 161 0.016
cellular calcium ion homeostasis GO:0006874 160 0.016
organonitrogen compound biosynthetic process GO:1901566 167 0.016
Human
response to oxidative stress GO:0006979 186 0.016
ras protein signal transduction GO:0007265 29 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
response to acid chemical GO:0001101 222 0.016
glycosyl compound metabolic process GO:1901657 182 0.016
neurological system process GO:0050877 219 0.016
divalent inorganic cation homeostasis GO:0072507 165 0.016
response to nutrient GO:0007584 248 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
response to other organism GO:0051707 220 0.016
cellular cation homeostasis GO:0030003 180 0.016
positive regulation of cell development GO:0010720 176 0.016
regulation of cell projection organization GO:0031344 175 0.016
calcium ion transport GO:0006816 131 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
proteolysis GO:0006508 175 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
response to biotic stimulus GO:0009607 226 0.015
intracellular transport GO:0046907 185 0.015
response to glucocorticoid GO:0051384 223 0.015
response to lipopolysaccharide GO:0032496 191 0.015
regulation of hormone secretion GO:0046883 106 0.015
negative regulation of response to stimulus GO:0048585 155 0.015
response to estradiol GO:0032355 164 0.015
inflammatory response GO:0006954 150 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
macromolecule localization GO:0033036 252 0.015
oxidation reduction process GO:0055114 304 0.015
blood circulation GO:0008015 183 0.015
response to bacterium GO:0009617 200 0.015
gland development GO:0048732 155 0.015
response to carbohydrate GO:0009743 183 0.015
response to monosaccharide GO:0034284 159 0.015
response to ketone GO:1901654 182 0.015
circulatory system process GO:0003013 183 0.015
response to toxic substance GO:0009636 133 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
single organism intracellular transport GO:1902582 166 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
regeneration GO:0031099 163 0.015
positive regulation of nervous system development GO:0051962 178 0.015
axis specification GO:0009798 4 0.015
organelle organization GO:0006996 266 0.014
nucleoside metabolic process GO:0009116 179 0.014
rhythmic process GO:0048511 156 0.014
cellular response to peptide GO:1901653 133 0.014
response to hexose GO:0009746 144 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
regulation of protein modification process GO:0031399 194 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
negative regulation of rna biosynthetic process GO:1902679 118 0.014
divalent metal ion transport GO:0070838 132 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
negative regulation of rna metabolic process GO:0051253 123 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
response to estrogen GO:0043627 232 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
regulation of membrane potential GO:0042391 110 0.014
divalent inorganic cation transport GO:0072511 134 0.014
negative regulation of nucleic acid templated transcription GO:1903507 117 0.014
negative regulation of cell communication GO:0010648 158 0.014
cell type specific apoptotic process GO:0097285 134 0.014
positive regulation of signal transduction GO:0009967 175 0.013
amide transport GO:0042886 105 0.013
heterocycle catabolic process GO:0046700 167 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
organic cyclic compound catabolic process GO:1901361 175 0.013
developmental process involved in reproduction GO:0003006 159 0.013
regulation of synaptic transmission GO:0050804 141 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
neuron death GO:0070997 127 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
multi multicellular organism process GO:0044706 138 0.013
reproductive system development GO:0061458 128 0.013
regulation of peptide secretion GO:0002791 82 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
regulation of anatomical structure size GO:0090066 135 0.013
organic anion transport GO:0015711 132 0.013
regulation of response to stress GO:0080134 126 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
regulation of immune system process GO:0002682 123 0.013
gamete generation GO:0007276 124 0.013
response to mechanical stimulus GO:0009612 134 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
regulation of cell motility GO:2000145 131 0.013
negative regulation of molecular function GO:0044092 133 0.012
response to radiation GO:0009314 137 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
negative regulation of developmental process GO:0051093 125 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
protein localization GO:0008104 191 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
regulation of neuron death GO:1901214 115 0.012
positive regulation of protein modification process GO:0031401 142 0.012
response to alkaloid GO:0043279 132 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
growth GO:0040007 165 0.012
action potential GO:0001508 54 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
regulation of peptide transport GO:0090087 87 0.012
negative regulation of cell proliferation GO:0008285 119 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
regulation of hydrolase activity GO:0051336 143 0.012
cytoplasmic transport GO:0016482 115 0.012
gastrulation GO:0007369 2 0.012
regulation of peptide hormone secretion GO:0090276 80 0.012
organ regeneration GO:0031100 101 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
cell activation GO:0001775 97 0.012
regulation of cell migration GO:0030334 128 0.012
peptide transport GO:0015833 97 0.012
cell adhesion GO:0007155 110 0.012
immune response GO:0006955 104 0.012
negative regulation of innate immune response GO:0045824 4 0.012
behavior GO:0007610 205 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
negative regulation of secretion GO:0051048 82 0.011
limb morphogenesis GO:0035108 4 0.011
female pregnancy GO:0007565 122 0.011
nucleotide catabolic process GO:0009166 139 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
embryonic pattern specification GO:0009880 1 0.011
transmission of nerve impulse GO:0019226 42 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
regulation of neuron apoptotic process GO:0043523 83 0.011
carboxylic acid transport GO:0046942 115 0.011
appendage morphogenesis GO:0035107 4 0.011
peptide hormone secretion GO:0030072 84 0.011
neuronal action potential GO:0019228 35 0.011
sex differentiation GO:0007548 113 0.011
heart morphogenesis GO:0003007 3 0.011
regulation of response to external stimulus GO:0032101 106 0.011
negative regulation of secretion by cell GO:1903531 72 0.011
response to reactive oxygen species GO:0000302 120 0.011
eye morphogenesis GO:0048592 4 0.011
salivary gland development GO:0007431 3 0.011
chromosome segregation GO:0007059 2 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.011
regulation of locomotion GO:0040012 148 0.011
regulation of blood circulation GO:1903522 110 0.011
protein transport GO:0015031 132 0.011
vascular process in circulatory system GO:0003018 96 0.011
biological adhesion GO:0022610 110 0.011
reproductive structure development GO:0048608 128 0.011
regulation of metal ion transport GO:0010959 118 0.011
mapk cascade GO:0000165 140 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
embryonic appendage morphogenesis GO:0035113 4 0.011
lipid storage GO:0019915 1 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
spermatogenesis GO:0007283 99 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.010
negative regulation of cell differentiation GO:0045596 99 0.010
cellular component morphogenesis GO:0032989 155 0.010
male gamete generation GO:0048232 99 0.010
regulation of anatomical structure morphogenesis GO:0022603 141 0.010
nucleoside phosphate catabolic process GO:1901292 140 0.010
positive regulation of cell projection organization GO:0031346 111 0.010
nucleotide biosynthetic process GO:0009165 98 0.010
chemosensory behavior GO:0007635 2 0.010
reactive nitrogen species metabolic process GO:2001057 1 0.010
sequestering of metal ion GO:0051238 9 0.010
forebrain development GO:0030900 98 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
vesicle mediated transport GO:0016192 181 0.010
peptide secretion GO:0002790 86 0.010
aromatic compound catabolic process GO:0019439 168 0.010
cellular response to external stimulus GO:0071496 118 0.010
organic acid transport GO:0015849 116 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
regulation of blood vessel size GO:0050880 89 0.010
bmp signaling pathway GO:0030509 4 0.010
palate development GO:0060021 2 0.010
purine containing compound catabolic process GO:0072523 138 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
organic hydroxy compound metabolic process GO:1901615 115 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
purine nucleoside catabolic process GO:0006152 124 0.010
establishment of protein localization GO:0045184 141 0.010
cellular macromolecule localization GO:0070727 122 0.010
purine ribonucleoside catabolic process GO:0046130 124 0.010

Sptlc3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.028
musculoskeletal system disease DOID:17 0 0.014
sensory system disease DOID:0050155 0 0.014
disease of metabolism DOID:0014667 0 0.012
central nervous system disease DOID:331 0 0.012
connective tissue disease DOID:65 0 0.010