Rattus norvegicus

0 known processes

Sptlc1

serine palmitoyltransferase, long chain base subunit 1

(Aliases: Lcb1,Spt1,RGD1306617)

Sptlc1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
catabolic process GO:0009056 351 0.111
cellular catabolic process GO:0044248 295 0.074
single organism catabolic process GO:0044712 283 0.064
regulation of phosphate metabolic process GO:0019220 349 0.055
nitrogen compound transport GO:0071705 229 0.050
ribonucleoside metabolic process GO:0009119 174 0.047
ribonucleotide catabolic process GO:0009261 136 0.045
regulation of phosphorus metabolic process GO:0051174 349 0.045
purine ribonucleotide metabolic process GO:0009150 227 0.043
organic substance catabolic process GO:1901575 316 0.043
anion transport GO:0006820 178 0.042
cellular response to stress GO:0033554 269 0.041
regulation of molecular function GO:0065009 398 0.040
organophosphate metabolic process GO:0019637 370 0.039
macromolecular complex subunit organization GO:0043933 339 0.037
cellular amino acid metabolic process GO:0006520 107 0.036
positive regulation of phosphate metabolic process GO:0045937 262 0.035
regulation of phosphorylation GO:0042325 248 0.034
organonitrogen compound catabolic process GO:1901565 179 0.034
protein phosphorylation GO:0006468 345 0.034
positive regulation of phosphorus metabolic process GO:0010562 262 0.033
negative regulation of multicellular organismal process GO:0051241 203 0.033
regulation of nucleoside metabolic process GO:0009118 66 0.033
nucleobase containing small molecule metabolic process GO:0055086 316 0.032
regulation of cell proliferation GO:0042127 359 0.031
glycosyl compound metabolic process GO:1901657 182 0.031
regulation of intracellular signal transduction GO:1902531 218 0.030
nucleoside catabolic process GO:0009164 126 0.029
heterocycle catabolic process GO:0046700 167 0.029
intracellular signal transduction GO:0035556 314 0.029
neuron differentiation GO:0030182 368 0.029
homeostatic process GO:0042592 331 0.029
purine containing compound metabolic process GO:0072521 253 0.028
ribonucleotide metabolic process GO:0009259 231 0.028
nucleoside phosphate catabolic process GO:1901292 140 0.028
ras protein signal transduction GO:0007265 29 0.028
ribose phosphate metabolic process GO:0019693 235 0.028
purine ribonucleoside catabolic process GO:0046130 124 0.027
organophosphate catabolic process GO:0046434 148 0.027
cellular component biogenesis GO:0044085 368 0.027
chemical homeostasis GO:0048878 292 0.026
glycosyl compound catabolic process GO:1901658 126 0.025
regulation of hydrolase activity GO:0051336 143 0.025
regulation of cellular component organization GO:0051128 368 0.025
nucleobase containing compound catabolic process GO:0034655 152 0.025
neuron development GO:0048666 286 0.025
cellular amine metabolic process GO:0044106 38 0.025
cellular nitrogen compound catabolic process GO:0044270 163 0.025
transmembrane transport GO:0055085 412 0.024
protein complex subunit organization GO:0071822 302 0.024
ribonucleoside triphosphate catabolic process GO:0009203 122 0.024
response to inorganic substance GO:0010035 377 0.024
cellular response to hormone stimulus GO:0032870 247 0.024
protein heterooligomerization GO:0051291 89 0.024
carbohydrate derivative metabolic process GO:1901135 346 0.024
purine nucleoside metabolic process GO:0042278 169 0.024
regulation of cellular protein metabolic process GO:0032268 267 0.024
protein complex biogenesis GO:0070271 263 0.023
single organism biosynthetic process GO:0044711 342 0.023
regulation of programmed cell death GO:0043067 341 0.023
regulation of multicellular organismal development GO:2000026 376 0.023
macromolecule localization GO:0033036 252 0.023
nucleoside triphosphate catabolic process GO:0009143 123 0.023
programmed cell death GO:0012501 392 0.023
regulation of cell differentiation GO:0045595 320 0.023
protein oligomerization GO:0051259 191 0.023
neuron projection development GO:0031175 273 0.023
multicellular organismal reproductive process GO:0048609 233 0.023
secretion by cell GO:0032940 248 0.022
ribonucleoside catabolic process GO:0042454 126 0.022
hormone secretion GO:0046879 115 0.022
rna metabolic process GO:0016070 406 0.022
regulation of protein metabolic process GO:0051246 289 0.022
intracellular transport GO:0046907 185 0.022
regulation of rab protein signal transduction GO:0032483 3 0.022
response to extracellular stimulus GO:0009991 380 0.022
anatomical structure morphogenesis GO:0009653 298 0.022
nucleotide metabolic process GO:0009117 279 0.022
purine nucleotide metabolic process GO:0006163 229 0.022
positive regulation of molecular function GO:0044093 230 0.022
ion transmembrane transport GO:0034220 365 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
negative regulation of neuron differentiation GO:0045665 62 0.022
nucleoside triphosphate metabolic process GO:0009141 144 0.022
single organism reproductive process GO:0044702 297 0.021
positive regulation of cell death GO:0010942 184 0.021
reproductive process GO:0022414 372 0.021
small gtpase mediated signal transduction GO:0007264 36 0.021
positive regulation of programmed cell death GO:0043068 157 0.021
negative regulation of developmental process GO:0051093 125 0.021
purine nucleoside triphosphate metabolic process GO:0009144 141 0.021
cell projection organization GO:0030030 302 0.021
amine metabolic process GO:0009308 38 0.020
multicellular organism reproduction GO:0032504 233 0.020
negative regulation of metabolic process GO:0009892 331 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.020
regulation of signal transduction GO:0009966 318 0.020
response to transition metal nanoparticle GO:1990267 122 0.020
aromatic compound catabolic process GO:0019439 168 0.020
regulation of cell development GO:0060284 263 0.020
cellular homeostasis GO:0019725 252 0.020
cellular component assembly GO:0022607 360 0.020
regulation of apoptotic process GO:0042981 335 0.020
anion transmembrane transport GO:0098656 77 0.019
organic cyclic compound catabolic process GO:1901361 175 0.019
response to oxygen levels GO:0070482 265 0.019
nucleic acid templated transcription GO:0097659 379 0.019
purine ribonucleoside metabolic process GO:0046128 168 0.019
response to ethanol GO:0045471 162 0.019
reproduction GO:0000003 245 0.019
positive regulation of nucleoside metabolic process GO:0045979 55 0.019
regulation of catalytic activity GO:0050790 304 0.019
cellular chemical homeostasis GO:0055082 247 0.019
regulation of hormone levels GO:0010817 187 0.019
cellular response to cytokine stimulus GO:0071345 127 0.019
regulation of neuron differentiation GO:0045664 208 0.019
negative regulation of cellular metabolic process GO:0031324 281 0.019
apoptotic process GO:0006915 381 0.018
purine nucleotide catabolic process GO:0006195 136 0.018
membrane organization GO:0061024 94 0.018
regulation of secretion GO:0051046 224 0.018
response to nutrient levels GO:0031667 370 0.018
regulation of cellular catabolic process GO:0031329 101 0.018
regulation of cellular ketone metabolic process GO:0010565 27 0.018
regulation of rna biosynthetic process GO:2001141 381 0.018
response to decreased oxygen levels GO:0036293 237 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.018
response to hypoxia GO:0001666 231 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
negative regulation of cell communication GO:0010648 158 0.018
lipid metabolic process GO:0006629 283 0.018
organic hydroxy compound metabolic process GO:1901615 115 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.017
multi organism reproductive process GO:0044703 262 0.017
positive regulation of multicellular organismal process GO:0051240 387 0.017
regulation of purine nucleotide metabolic process GO:1900542 115 0.017
regulation of cell projection organization GO:0031344 175 0.017
hormone transport GO:0009914 121 0.017
response to peptide GO:1901652 292 0.017
negative regulation of neurogenesis GO:0050768 78 0.017
metal ion transport GO:0030001 289 0.017
response to glucose GO:0009749 136 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 53 0.017
response to insulin GO:0032868 133 0.016
monovalent inorganic cation transport GO:0015672 172 0.016
organophosphate biosynthetic process GO:0090407 143 0.016
cation transport GO:0006812 382 0.016
oxoacid metabolic process GO:0043436 290 0.016
carbohydrate derivative catabolic process GO:1901136 147 0.016
regulation of protein modification process GO:0031399 194 0.016
regulation of system process GO:0044057 208 0.016
regulation of catabolic process GO:0009894 113 0.016
proteolysis GO:0006508 175 0.016
cellular ion homeostasis GO:0006873 184 0.016
cellular response to nitrogen compound GO:1901699 210 0.016
regulation of hormone secretion GO:0046883 106 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
organic acid transport GO:0015849 116 0.016
purine containing compound catabolic process GO:0072523 138 0.016
protein autophosphorylation GO:0046777 66 0.016
protein localization GO:0008104 191 0.015
regulation of neuron projection development GO:0010975 161 0.015
purine ribonucleotide catabolic process GO:0009154 136 0.015
regulation of neurogenesis GO:0050767 247 0.015
organic acid metabolic process GO:0006082 292 0.015
protein complex assembly GO:0006461 263 0.015
inorganic ion transmembrane transport GO:0098660 229 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
secretion GO:0046903 307 0.015
regulation of nucleotide catabolic process GO:0030811 65 0.015
nucleoside metabolic process GO:0009116 179 0.015
regulation of nucleotide metabolic process GO:0006140 117 0.015
spindle organization GO:0007051 2 0.015
cell cell signaling GO:0007267 335 0.015
negative regulation of transport GO:0051051 136 0.015
phospholipid metabolic process GO:0006644 61 0.015
cellular lipid metabolic process GO:0044255 208 0.014
regulation of nervous system development GO:0051960 264 0.014
positive regulation of catabolic process GO:0009896 78 0.014
single organism intracellular transport GO:1902582 166 0.014
cellular response to oxygen containing compound GO:1901701 386 0.014
atp metabolic process GO:0046034 72 0.014
negative regulation of cell development GO:0010721 82 0.014
aging GO:0007568 241 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
response to cytokine GO:0034097 215 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.014
regulation of secretion by cell GO:1903530 208 0.014
glycerolipid metabolic process GO:0046486 67 0.014
purine nucleoside catabolic process GO:0006152 124 0.014
response to metal ion GO:0010038 253 0.014
positive regulation of cell proliferation GO:0008284 249 0.014
response to hexose GO:0009746 144 0.014
cardiac ventricle development GO:0003231 1 0.014
nucleotide catabolic process GO:0009166 139 0.013
negative regulation of response to stimulus GO:0048585 155 0.013
response to peptide hormone GO:0043434 278 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
chromosome segregation GO:0007059 2 0.013
negative regulation of signaling GO:0023057 157 0.013
synaptic transmission GO:0007268 235 0.013
cellular response to endogenous stimulus GO:0071495 377 0.013
negative regulation of nervous system development GO:0051961 79 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 55 0.013
carboxylic acid metabolic process GO:0019752 289 0.013
carboxylic acid transport GO:0046942 115 0.013
head development GO:0060322 247 0.013
cellular response to external stimulus GO:0071496 118 0.013
tissue development GO:0009888 252 0.013
cellular response to glucose stimulus GO:0071333 65 0.013
cation homeostasis GO:0055080 195 0.013
response to radiation GO:0009314 137 0.013
positive regulation of protein phosphorylation GO:0001934 135 0.013
brain development GO:0007420 247 0.013
glycerophospholipid metabolic process GO:0006650 47 0.013
positive regulation of protein modification process GO:0031401 142 0.013
lysosomal transport GO:0007041 8 0.013
central nervous system development GO:0007417 311 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
peptide hormone secretion GO:0030072 84 0.012
single organism organelle organization GO:1902589 180 0.012
nucleoside monophosphate metabolic process GO:0009123 93 0.012
golgi vesicle transport GO:0048193 22 0.012
positive regulation of cellular catabolic process GO:0031331 71 0.012
positive regulation of catalytic activity GO:0043085 184 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
lipid biosynthetic process GO:0008610 128 0.012
purine nucleoside triphosphate catabolic process GO:0009146 122 0.012
purine nucleoside monophosphate metabolic process GO:0009126 84 0.012
response to carbohydrate GO:0009743 183 0.012
macromolecular complex assembly GO:0065003 273 0.012
rab protein signal transduction GO:0032482 1 0.012
cation transmembrane transport GO:0098655 263 0.012
negative regulation of organ growth GO:0046621 3 0.012
regulation of fat cell differentiation GO:0045598 3 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
regulation of nucleic acid templated transcription GO:1903506 380 0.012
response to monosaccharide GO:0034284 159 0.012
negative regulation of cellular component organization GO:0051129 83 0.012
positive regulation of rab gtpase activity GO:0032851 3 0.012
cellular ketone metabolic process GO:0042180 51 0.012
multicellular organism growth GO:0035264 1 0.012
ribonucleoside monophosphate metabolic process GO:0009161 88 0.011
single organism membrane organization GO:0044802 74 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
regulation of purine nucleotide catabolic process GO:0033121 65 0.011
transcription dna templated GO:0006351 377 0.011
regulation of cellular localization GO:0060341 263 0.011
organic anion transport GO:0015711 132 0.011
ion homeostasis GO:0050801 212 0.011
amide transport GO:0042886 105 0.011
signal release GO:0023061 145 0.011
male gamete generation GO:0048232 99 0.011
carbohydrate homeostasis GO:0033500 75 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
response to bacterium GO:0009617 200 0.011
regulation of transcription dna templated GO:0006355 374 0.011
positive regulation of response to stimulus GO:0048584 285 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.011
protein transport GO:0015031 132 0.011
glucose homeostasis GO:0042593 75 0.011
rna localization GO:0006403 4 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
gamete generation GO:0007276 124 0.011
gtp catabolic process GO:0006184 71 0.011
regulation of mapk cascade GO:0043408 116 0.011
circulatory system process GO:0003013 183 0.011
cellular component morphogenesis GO:0032989 155 0.010
peptide secretion GO:0002790 86 0.010
cellular macromolecule localization GO:0070727 122 0.010
cellular response to organonitrogen compound GO:0071417 197 0.010
positive regulation of cellular component organization GO:0051130 200 0.010
lipid storage GO:0019915 1 0.010
regulation of membrane potential GO:0042391 110 0.010
cellular metal ion homeostasis GO:0006875 172 0.010
response to axon injury GO:0048678 59 0.010
heart morphogenesis GO:0003007 3 0.010
axis specification GO:0009798 4 0.010

Sptlc1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.012