Rattus norvegicus

0 known processes

Ece2

endothelin-converting enzyme 2

Ece2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
cellular component biogenesis GO:0044085 368 0.086
cell cell signaling GO:0007267 335 0.064
macromolecular complex subunit organization GO:0043933 339 0.059
cellular component assembly GO:0022607 360 0.058
protein complex subunit organization GO:0071822 302 0.052
transmembrane transport GO:0055085 412 0.052
regulation of secretion GO:0051046 224 0.049
neuron differentiation GO:0030182 368 0.049
protein complex assembly GO:0006461 263 0.045
cell projection organization GO:0030030 302 0.045
negative regulation of metabolic process GO:0009892 331 0.043
regulation of cell differentiation GO:0045595 320 0.043
nucleoside phosphate metabolic process GO:0006753 283 0.042
Rat
cellular response to nitrogen compound GO:1901699 210 0.042
single organism biosynthetic process GO:0044711 342 0.041
Rat
nucleobase containing small molecule metabolic process GO:0055086 316 0.040
Rat
regulation of cell development GO:0060284 263 0.040
secretion GO:0046903 307 0.040
cellular chemical homeostasis GO:0055082 247 0.038
positive regulation of cellular component organization GO:0051130 200 0.038
cellular homeostasis GO:0019725 252 0.037
positive regulation of transport GO:0051050 245 0.037
protein phosphorylation GO:0006468 345 0.037
cellular response to organonitrogen compound GO:0071417 197 0.037
protein complex biogenesis GO:0070271 263 0.037
response to inorganic substance GO:0010035 377 0.036
Rat
organophosphate metabolic process GO:0019637 370 0.035
Rat
regulation of multicellular organismal development GO:2000026 376 0.035
multicellular organism reproduction GO:0032504 233 0.035
organic acid transport GO:0015849 116 0.035
response to cytokine GO:0034097 215 0.034
reproductive process GO:0022414 372 0.034
regulation of synaptic transmission GO:0050804 141 0.034
organic substance catabolic process GO:1901575 316 0.034
organonitrogen compound biosynthetic process GO:1901566 167 0.034
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.034
Rat
programmed cell death GO:0012501 392 0.033
Rat
cellular response to oxygen containing compound GO:1901701 386 0.033
purine nucleoside triphosphate metabolic process GO:0009144 141 0.032
positive regulation of developmental process GO:0051094 283 0.032
nucleotide metabolic process GO:0009117 279 0.032
Rat
anatomical structure morphogenesis GO:0009653 298 0.032
protein homooligomerization GO:0051260 91 0.032
regulation of neuron projection development GO:0010975 161 0.032
neuron development GO:0048666 286 0.031
regulation of neuron differentiation GO:0045664 208 0.031
organelle organization GO:0006996 266 0.031
positive regulation of phosphorus metabolic process GO:0010562 262 0.031
Rat
multi organism reproductive process GO:0044703 262 0.031
organophosphate biosynthetic process GO:0090407 143 0.030
Rat
regulation of cellular component organization GO:0051128 368 0.030
nucleoside metabolic process GO:0009116 179 0.029
regulation of neurogenesis GO:0050767 247 0.029
regulation of purine nucleotide metabolic process GO:1900542 115 0.029
Rat
regulation of catalytic activity GO:0050790 304 0.028
carbohydrate derivative biosynthetic process GO:1901137 124 0.028
Rat
positive regulation of neuron projection development GO:0010976 99 0.028
macromolecular complex assembly GO:0065003 273 0.027
positive regulation of cell development GO:0010720 176 0.027
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.027
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.027
Rat
cellular amino acid metabolic process GO:0006520 107 0.027
regulation of secretion by cell GO:1903530 208 0.027
neuron projection development GO:0031175 273 0.027
homeostatic process GO:0042592 331 0.027
synaptic transmission GO:0007268 235 0.027
positive regulation of cell communication GO:0010647 271 0.027
Rat
regulation of phosphorus metabolic process GO:0051174 349 0.027
Rat
purine containing compound metabolic process GO:0072521 253 0.026
Rat
cellular response to organic cyclic compound GO:0071407 202 0.026
regulation of nervous system development GO:0051960 264 0.026
intracellular signal transduction GO:0035556 314 0.026
Rat
aromatic compound catabolic process GO:0019439 168 0.026
single organism catabolic process GO:0044712 283 0.026
multicellular organismal reproductive process GO:0048609 233 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.025
Rat
protein oligomerization GO:0051259 191 0.025
lipid metabolic process GO:0006629 283 0.025
catabolic process GO:0009056 351 0.025
positive regulation of cell differentiation GO:0045597 217 0.025
positive regulation of nervous system development GO:0051962 178 0.025
anion transport GO:0006820 178 0.025
purine ribonucleoside catabolic process GO:0046130 124 0.025
glycosyl compound metabolic process GO:1901657 182 0.024
regulation of molecular function GO:0065009 398 0.024
organophosphate catabolic process GO:0046434 148 0.024
ion transmembrane transport GO:0034220 365 0.024
ribose phosphate metabolic process GO:0019693 235 0.024
Rat
apoptotic process GO:0006915 381 0.023
Rat
cellular response to stress GO:0033554 269 0.023
positive regulation of neuron differentiation GO:0045666 126 0.023
ribonucleoside metabolic process GO:0009119 174 0.023
regulation of cellular amino acid metabolic process GO:0006521 2 0.023
cation transmembrane transport GO:0098655 263 0.023
organic acid metabolic process GO:0006082 292 0.022
ras protein signal transduction GO:0007265 29 0.022
cell part morphogenesis GO:0032990 123 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
positive regulation of catalytic activity GO:0043085 184 0.022
small gtpase mediated signal transduction GO:0007264 36 0.022
response to mechanical stimulus GO:0009612 134 0.022
Rat
ribonucleotide biosynthetic process GO:0009260 85 0.022
Rat
response to decreased oxygen levels GO:0036293 237 0.021
Rat
positive regulation of cell projection organization GO:0031346 111 0.021
aging GO:0007568 241 0.021
chemical homeostasis GO:0048878 292 0.021
nucleoside triphosphate metabolic process GO:0009141 144 0.021
regulation of organelle organization GO:0033043 80 0.021
regulation of phosphorylation GO:0042325 248 0.021
Rat
negative regulation of macromolecule metabolic process GO:0010605 260 0.021
cardiac chamber development GO:0003205 1 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.021
head development GO:0060322 247 0.021
amine metabolic process GO:0009308 38 0.021
oxoacid metabolic process GO:0043436 290 0.020
regulation of cellular localization GO:0060341 263 0.020
regulation of protein modification process GO:0031399 194 0.020
cellular catabolic process GO:0044248 295 0.020
regulation of cell projection organization GO:0031344 175 0.020
cellular amine metabolic process GO:0044106 38 0.020
cellular response to endogenous stimulus GO:0071495 377 0.020
circulatory system process GO:0003013 183 0.020
Rat
monovalent inorganic cation transport GO:0015672 172 0.020
cellular component morphogenesis GO:0032989 155 0.020
response to nutrient levels GO:0031667 370 0.020
cation homeostasis GO:0055080 195 0.020
reproduction GO:0000003 245 0.020
ribonucleoside triphosphate metabolic process GO:0009199 141 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
Rat
purine nucleotide metabolic process GO:0006163 229 0.019
Rat
ribonucleotide metabolic process GO:0009259 231 0.019
Rat
regulation of hormone levels GO:0010817 187 0.019
Human
cellular response to growth factor stimulus GO:0071363 162 0.019
response to carbohydrate GO:0009743 183 0.019
response to extracellular stimulus GO:0009991 380 0.019
cellular component movement GO:0006928 248 0.019
secretion by cell GO:0032940 248 0.019
purine nucleoside metabolic process GO:0042278 169 0.019
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.019
regulation of anatomical structure size GO:0090066 135 0.019
Rat
purine ribonucleoside metabolic process GO:0046128 168 0.019
cellular ion homeostasis GO:0006873 184 0.018
regulation of apoptotic process GO:0042981 335 0.018
cellular ketone metabolic process GO:0042180 51 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
regulation of phosphate metabolic process GO:0019220 349 0.018
Rat
actin filament based process GO:0030029 86 0.018
heterocycle catabolic process GO:0046700 167 0.018
positive regulation of response to stimulus GO:0048584 285 0.018
Rat
regulation of protein metabolic process GO:0051246 289 0.018
organic cyclic compound catabolic process GO:1901361 175 0.018
positive regulation of biosynthetic process GO:0009891 319 0.018
Rat
nucleoside phosphate biosynthetic process GO:1901293 102 0.018
Rat
regulation of nucleotide catabolic process GO:0030811 65 0.018
nitrogen compound transport GO:0071705 229 0.018
ion homeostasis GO:0050801 212 0.018
single organism reproductive process GO:0044702 297 0.017
ribonucleoside triphosphate catabolic process GO:0009203 122 0.017
positive regulation of molecular function GO:0044093 230 0.017
cellular lipid metabolic process GO:0044255 208 0.017
metal ion transport GO:0030001 289 0.017
inflammatory response GO:0006954 150 0.017
nucleoside triphosphate catabolic process GO:0009143 123 0.017
locomotion GO:0040011 237 0.017
organonitrogen compound catabolic process GO:1901565 179 0.017
positive regulation of cellular biosynthetic process GO:0031328 295 0.017
Rat
spindle organization GO:0007051 2 0.017
carboxylic acid metabolic process GO:0019752 289 0.016
positive regulation of ion transport GO:0043270 94 0.016
response to oxygen levels GO:0070482 265 0.016
Rat
negative regulation of cell communication GO:0010648 158 0.016
negative regulation of signaling GO:0023057 157 0.016
single organism membrane organization GO:0044802 74 0.016
metal ion homeostasis GO:0055065 186 0.016
embryonic pattern specification GO:0009880 1 0.016
response to growth factor GO:0070848 189 0.016
purine nucleoside catabolic process GO:0006152 124 0.016
regulation of hydrolase activity GO:0051336 143 0.016
central nervous system development GO:0007417 311 0.016
hormone transport GO:0009914 121 0.016
glycosyl compound catabolic process GO:1901658 126 0.016
maintenance of location GO:0051235 17 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
regulation of synaptic plasticity GO:0048167 70 0.015
response to corticosteroid GO:0031960 235 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
response to acid chemical GO:0001101 222 0.015
regulation of cyclic nucleotide biosynthetic process GO:0030802 45 0.015
Rat
positive regulation of gene expression GO:0010628 244 0.015
acid secretion GO:0046717 48 0.015
circulatory system development GO:0072359 134 0.015
positive regulation of nucleotide metabolic process GO:0045981 91 0.015
Rat
cell projection morphogenesis GO:0048858 123 0.015
sexual reproduction GO:0019953 148 0.015
endocytosis GO:0006897 84 0.015
regulation of transmembrane transport GO:0034762 122 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
nucleoside catabolic process GO:0009164 126 0.014
single organism intracellular transport GO:1902582 166 0.014
blood circulation GO:0008015 183 0.014
Rat
gastrulation GO:0007369 2 0.014
developmental process involved in reproduction GO:0003006 159 0.014
regulation of intracellular signal transduction GO:1902531 218 0.014
Rat
cation transport GO:0006812 382 0.014
response to radiation GO:0009314 137 0.014
positive regulation of secretion GO:0051047 140 0.014
chromosome segregation GO:0007059 2 0.014
atp metabolic process GO:0046034 72 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
purine nucleoside triphosphate catabolic process GO:0009146 122 0.014
purine containing compound catabolic process GO:0072523 138 0.014
camp biosynthetic process GO:0006171 47 0.014
Rat
neuron projection morphogenesis GO:0048812 122 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
regulation of ion transport GO:0043269 245 0.013
positive regulation of signaling GO:0023056 270 0.013
Rat
synaptic growth at neuromuscular junction GO:0051124 1 0.013
lipid biosynthetic process GO:0008610 128 0.013
amide transport GO:0042886 105 0.013
cell morphogenesis involved in differentiation GO:0000904 119 0.013
growth GO:0040007 165 0.013
vesicle mediated transport GO:0016192 181 0.013
neuron neuron synaptic transmission GO:0007270 60 0.013
response to estradiol GO:0032355 164 0.013
brain development GO:0007420 247 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
cardiovascular system development GO:0072358 134 0.013
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.013
regulation of rna biosynthetic process GO:2001141 381 0.013
calcium ion transport GO:0006816 131 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
response to estrogen GO:0043627 232 0.013
regulation of ion transmembrane transport GO:0034765 121 0.013
gtp metabolic process GO:0046039 72 0.013
macromolecule localization GO:0033036 252 0.013
response to ammonium ion GO:0060359 71 0.013
gamete generation GO:0007276 124 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
Rat
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
divalent inorganic cation transport GO:0072511 134 0.012
multi multicellular organism process GO:0044706 138 0.012
sequestering of metal ion GO:0051238 9 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
positive regulation of protein modification process GO:0031401 142 0.012
response to glucose GO:0009749 136 0.012
negative regulation of cell development GO:0010721 82 0.012
transcription dna templated GO:0006351 377 0.012
regulation of dendrite development GO:0050773 59 0.012
purine containing compound biosynthetic process GO:0072522 85 0.012
Rat
positive regulation of cellular component biogenesis GO:0044089 55 0.012
hormone secretion GO:0046879 115 0.012
cell morphogenesis GO:0000902 142 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
response to wounding GO:0009611 254 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
Rat
defense response GO:0006952 194 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
circadian rhythm GO:0007623 88 0.012
axis specification GO:0009798 4 0.012
regulation of cellular protein metabolic process GO:0032268 267 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
Rat
negative regulation of molecular function GO:0044092 133 0.012
regulation of rna metabolic process GO:0051252 391 0.012
cellular response to lipid GO:0071396 201 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.011
regulation of kinase activity GO:0043549 117 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
organic anion transport GO:0015711 132 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
muscle contraction GO:0006936 88 0.011
membrane organization GO:0061024 94 0.011
cytosolic calcium ion homeostasis GO:0051480 140 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
Rat
positive regulation of nucleoside metabolic process GO:0045979 55 0.011
purine nucleotide biosynthetic process GO:0006164 83 0.011
Rat
response to cocaine GO:0042220 39 0.011
regulation of peptide secretion GO:0002791 82 0.011
cellular cation homeostasis GO:0030003 180 0.011
behavior GO:0007610 205 0.011
rho protein signal transduction GO:0007266 11 0.011
regulation of catabolic process GO:0009894 113 0.011
lipid storage GO:0019915 1 0.011
forebrain development GO:0030900 98 0.011
dna metabolic process GO:0006259 96 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
positive regulation of nucleotide biosynthetic process GO:0030810 36 0.011
Rat
nucleotide catabolic process GO:0009166 139 0.011
cognition GO:0050890 92 0.011
single organism organelle organization GO:1902589 180 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
anterior posterior pattern specification GO:0009952 1 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
Rat
cyclic purine nucleotide metabolic process GO:0052652 62 0.011
Rat
negative regulation of catalytic activity GO:0043086 103 0.011
carbohydrate metabolic process GO:0005975 130 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
regulation of transferase activity GO:0051338 123 0.011
sequestering of calcium ion GO:0051208 8 0.011
peptide transport GO:0015833 97 0.011
intracellular transport GO:0046907 185 0.011
regulation of embryonic development GO:0045995 2 0.011
regulation of signal transduction GO:0009966 318 0.011
Rat
positive regulation of phosphorylation GO:0042327 177 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
positive regulation of nucleotide catabolic process GO:0030813 53 0.011
purine ribonucleotide biosynthetic process GO:0009152 81 0.011
Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
positive regulation of protein metabolic process GO:0051247 178 0.010
inorganic ion transmembrane transport GO:0098660 229 0.010
negative regulation of cellular component organization GO:0051129 83 0.010
response to hexose GO:0009746 144 0.010
carboxylic acid transport GO:0046942 115 0.010
regulation of proteasomal protein catabolic process GO:0061136 4 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
asymmetric stem cell division GO:0098722 2 0.010
regulation of response to stress GO:0080134 126 0.010
response to ketone GO:1901654 182 0.010
regulation of nucleoside metabolic process GO:0009118 66 0.010
positive regulation of cell morphogenesis involved in differentiation GO:0010770 41 0.010
endoplasmic reticulum organization GO:0007029 1 0.010
negative regulation of developmental process GO:0051093 125 0.010
multicellular organism growth GO:0035264 1 0.010
cardiac ventricle development GO:0003231 1 0.010
single organism cellular localization GO:1902580 102 0.010
response to ethanol GO:0045471 162 0.010
negative regulation of secretion GO:0051048 82 0.010
negative regulation of neurogenesis GO:0050768 78 0.010
positive regulation of signal transduction GO:0009967 175 0.010
Rat
somatic stem cell division GO:0048103 2 0.010

Ece2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
central nervous system disease DOID:331 0 0.016