Rattus norvegicus

0 known processes

Lrrc38

leucine rich repeat containing 38

(Aliases: RGD1311416)

Lrrc38 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of nucleic acid templated transcription GO:1903506 380 0.168
regulation of rna metabolic process GO:0051252 391 0.116
nucleic acid templated transcription GO:0097659 379 0.112
rna biosynthetic process GO:0032774 380 0.106
negative regulation of macromolecule metabolic process GO:0010605 260 0.091
regulation of transcription dna templated GO:0006355 374 0.085
organic acid metabolic process GO:0006082 292 0.084
cation transport GO:0006812 382 0.074
transcription dna templated GO:0006351 377 0.074
rna metabolic process GO:0016070 406 0.067
negative regulation of metabolic process GO:0009892 331 0.066
macromolecule localization GO:0033036 252 0.065
response to oxygen levels GO:0070482 265 0.058
cellular response to organic cyclic compound GO:0071407 202 0.056
regulation of rna biosynthetic process GO:2001141 381 0.055
divalent metal ion transport GO:0070838 132 0.055
cellular response to stress GO:0033554 269 0.055
carboxylic acid metabolic process GO:0019752 289 0.054
positive regulation of rna biosynthetic process GO:1902680 197 0.053
transcription from rna polymerase ii promoter GO:0006366 252 0.052
secretion by cell GO:0032940 248 0.052
response to glucocorticoid GO:0051384 223 0.051
response to external biotic stimulus GO:0043207 221 0.051
regulation of secretion by cell GO:1903530 208 0.050
taxis GO:0042330 67 0.048
regulation of cellular localization GO:0060341 263 0.045
calcium ion transport GO:0006816 131 0.045
neuron differentiation GO:0030182 368 0.044
response to hexose GO:0009746 144 0.044
response to peptide hormone GO:0043434 278 0.042
negative regulation of nucleic acid templated transcription GO:1903507 117 0.042
ion transmembrane transport GO:0034220 365 0.041
brain development GO:0007420 247 0.040
negative regulation of cell death GO:0060548 229 0.040
positive regulation of multicellular organismal process GO:0051240 387 0.040
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.039
positive regulation of intracellular signal transduction GO:1902533 138 0.039
regulation of ion transport GO:0043269 245 0.039
positive regulation of gene expression GO:0010628 244 0.038
regulation of molecular function GO:0065009 398 0.037
cellular lipid metabolic process GO:0044255 208 0.037
neurological system process GO:0050877 219 0.037
negative regulation of gene expression GO:0010629 199 0.037
response to hypoxia GO:0001666 231 0.036
regulation of signal transduction GO:0009966 318 0.036
oxoacid metabolic process GO:0043436 290 0.036
positive regulation of signaling GO:0023056 270 0.036
response to peptide GO:1901652 292 0.035
positive regulation of transcription dna templated GO:0045893 197 0.035
central nervous system development GO:0007417 311 0.035
transmembrane transport GO:0055085 412 0.034
g protein coupled receptor signaling pathway GO:0007186 242 0.034
positive regulation of biosynthetic process GO:0009891 319 0.033
response to monosaccharide GO:0034284 159 0.033
positive regulation of rna metabolic process GO:0051254 203 0.032
positive regulation of cell proliferation GO:0008284 249 0.032
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.032
reproductive process GO:0022414 372 0.032
response to decreased oxygen levels GO:0036293 237 0.031
head development GO:0060322 247 0.031
response to other organism GO:0051707 220 0.031
response to glucose GO:0009749 136 0.031
inorganic ion transmembrane transport GO:0098660 229 0.031
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
cell projection organization GO:0030030 302 0.030
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.030
anion transport GO:0006820 178 0.030
cellular response to oxygen containing compound GO:1901701 386 0.029
lipid metabolic process GO:0006629 283 0.029
response to carbohydrate GO:0009743 183 0.028
secretion GO:0046903 307 0.028
regulation of response to external stimulus GO:0032101 106 0.027
response to extracellular stimulus GO:0009991 380 0.027
homeostatic process GO:0042592 331 0.027
negative regulation of cellular metabolic process GO:0031324 281 0.027
cell migration GO:0016477 197 0.027
divalent inorganic cation transport GO:0072511 134 0.027
negative regulation of cellular biosynthetic process GO:0031327 161 0.027
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.026
oxidation reduction process GO:0055114 304 0.026
cellular response to hormone stimulus GO:0032870 247 0.026
response to corticosteroid GO:0031960 235 0.026
cell cell signaling GO:0007267 335 0.026
regulation of neuron death GO:1901214 115 0.025
regulation of cellular ketone metabolic process GO:0010565 27 0.025
regulation of apoptotic process GO:0042981 335 0.025
divalent inorganic cation homeostasis GO:0072507 165 0.025
response to ketone GO:1901654 182 0.024
multicellular organism growth GO:0035264 1 0.024
cellular ketone metabolic process GO:0042180 51 0.024
intracellular signal transduction GO:0035556 314 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
small molecule biosynthetic process GO:0044283 124 0.023
negative regulation of rna biosynthetic process GO:1902679 118 0.023
cell morphogenesis GO:0000902 142 0.023
positive regulation of response to external stimulus GO:0032103 51 0.023
positive regulation of nucleic acid templated transcription GO:1903508 197 0.023
metal ion transport GO:0030001 289 0.023
cellular amine metabolic process GO:0044106 38 0.022
regulation of metal ion transport GO:0010959 118 0.022
cellular amino acid metabolic process GO:0006520 107 0.022
regulation of calcium ion transport GO:0051924 77 0.022
hormone transport GO:0009914 121 0.022
signal release GO:0023061 145 0.022
positive regulation of nervous system development GO:0051962 178 0.022
monocarboxylic acid metabolic process GO:0032787 152 0.021
cellular response to alcohol GO:0097306 87 0.021
regulation of cellular component organization GO:0051128 368 0.021
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.021
apoptotic process GO:0006915 381 0.021
fatty acid metabolic process GO:0006631 99 0.021
response to acid chemical GO:0001101 222 0.021
female pregnancy GO:0007565 122 0.021
protein phosphorylation GO:0006468 345 0.021
response to metal ion GO:0010038 253 0.021
blood circulation GO:0008015 183 0.021
cellular chemical homeostasis GO:0055082 247 0.021
cellular response to steroid hormone stimulus GO:0071383 93 0.021
peptide secretion GO:0002790 86 0.020
positive regulation of cellular biosynthetic process GO:0031328 295 0.020
regulation of cell projection organization GO:0031344 175 0.020
positive regulation of cell projection organization GO:0031346 111 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
positive regulation of cell communication GO:0010647 271 0.020
positive regulation of cell differentiation GO:0045597 217 0.020
insulin secretion GO:0030073 69 0.020
lipid biosynthetic process GO:0008610 128 0.020
positive regulation of locomotion GO:0040017 102 0.020
regulation of cell development GO:0060284 263 0.020
regulation of multicellular organismal development GO:2000026 376 0.019
negative regulation of protein metabolic process GO:0051248 114 0.019
regulation of homeostatic process GO:0032844 101 0.019
response to radiation GO:0009314 137 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
cell motility GO:0048870 202 0.019
single organism biosynthetic process GO:0044711 342 0.019
transmission of nerve impulse GO:0019226 42 0.018
regulation of chemotaxis GO:0050920 29 0.018
neuron projection development GO:0031175 273 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
regulation of intracellular signal transduction GO:1902531 218 0.018
regulation of cell differentiation GO:0045595 320 0.018
negative regulation of transcription dna templated GO:0045892 116 0.018
chemical homeostasis GO:0048878 292 0.018
regulation of neurogenesis GO:0050767 247 0.018
steroid metabolic process GO:0008202 73 0.018
regulation of catalytic activity GO:0050790 304 0.018
lipid localization GO:0010876 62 0.018
response to ethanol GO:0045471 162 0.018
ion homeostasis GO:0050801 212 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.018
positive regulation of secretion by cell GO:1903532 128 0.017
multicellular organismal signaling GO:0035637 44 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
macromolecular complex assembly GO:0065003 273 0.017
cellular component movement GO:0006928 248 0.017
carbohydrate derivative metabolic process GO:1901135 346 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
tissue development GO:0009888 252 0.017
positive regulation of phosphate metabolic process GO:0045937 262 0.017
olfactory learning GO:0008355 1 0.017
regulation of neuron differentiation GO:0045664 208 0.017
sex differentiation GO:0007548 113 0.017
cellular response to endogenous stimulus GO:0071495 377 0.017
peptide hormone secretion GO:0030072 84 0.016
single organism intracellular transport GO:1902582 166 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.016
regulation of nervous system development GO:0051960 264 0.016
response to nutrient levels GO:0031667 370 0.016
regulation of phosphorus metabolic process GO:0051174 349 0.016
cellular cation homeostasis GO:0030003 180 0.016
nitrogen compound transport GO:0071705 229 0.016
monocarboxylic acid transport GO:0015718 52 0.016
lipid transport GO:0006869 61 0.016
negative regulation of neuron death GO:1901215 69 0.015
regulation of phosphorylation GO:0042325 248 0.015
protein heterooligomerization GO:0051291 89 0.015
single organism reproductive process GO:0044702 297 0.015
proteolysis GO:0006508 175 0.015
multi organism reproductive process GO:0044703 262 0.015
positive regulation of cellular protein metabolic process GO:0032270 167 0.015
regulation of protein metabolic process GO:0051246 289 0.015
aging GO:0007568 241 0.015
neuron death GO:0070997 127 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
protein complex assembly GO:0006461 263 0.015
nucleocytoplasmic transport GO:0006913 48 0.015
stress activated protein kinase signaling cascade GO:0031098 37 0.015
developmental process involved in reproduction GO:0003006 159 0.015
multi multicellular organism process GO:0044706 138 0.015
regulation of gtpase activity GO:0043087 57 0.015
negative regulation of programmed cell death GO:0043069 183 0.014
response to cytokine GO:0034097 215 0.014
negative regulation of molecular function GO:0044092 133 0.014
naphthalene containing compound metabolic process GO:0090420 2 0.014
cellular component morphogenesis GO:0032989 155 0.014
growth GO:0040007 165 0.014
cytoplasmic transport GO:0016482 115 0.014
b cell differentiation GO:0030183 2 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
response to oxidative stress GO:0006979 186 0.014
stress activated mapk cascade GO:0051403 35 0.014
calcium ion homeostasis GO:0055074 162 0.014
response to activity GO:0014823 73 0.014
positive regulation of homeostatic process GO:0032846 49 0.014
organophosphate metabolic process GO:0019637 370 0.014
regulation of neuron projection development GO:0010975 161 0.013
adult locomotory behavior GO:0008344 4 0.013
amine metabolic process GO:0009308 38 0.013
programmed cell death GO:0012501 392 0.013
positive regulation of cellular component movement GO:0051272 102 0.013
sequestering of calcium ion GO:0051208 8 0.013
response to biotic stimulus GO:0009607 226 0.013
positive regulation of ion transport GO:0043270 94 0.013
positive regulation of molecular function GO:0044093 230 0.013
terpenoid metabolic process GO:0006721 37 0.013
multicellular organism reproduction GO:0032504 233 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
immune response GO:0006955 104 0.013
diterpenoid metabolic process GO:0016101 33 0.013
smooth muscle cell proliferation GO:0048659 77 0.013
maintenance of location GO:0051235 17 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
negative regulation of signaling GO:0023057 157 0.013
development of primary sexual characteristics GO:0045137 107 0.013
neuron development GO:0048666 286 0.013
regulation of insulin secretion GO:0050796 65 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
organic acid biosynthetic process GO:0016053 83 0.013
fatty acid transport GO:0015908 25 0.013
organic hydroxy compound metabolic process GO:1901615 115 0.013
response to nutrient GO:0007584 248 0.013
locomotion GO:0040011 237 0.013
positive regulation of response to stimulus GO:0048584 285 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.013
organonitrogen compound biosynthetic process GO:1901566 167 0.013
positive regulation of secretion GO:0051047 140 0.012
negative regulation of cell communication GO:0010648 158 0.012
immune system process GO:0002376 204 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.012
organic substance catabolic process GO:1901575 316 0.012
regulation of hydrolase activity GO:0051336 143 0.012
regulation of hormone levels GO:0010817 187 0.012
intracellular receptor signaling pathway GO:0030522 35 0.012
catabolic process GO:0009056 351 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
positive regulation of signal transduction GO:0009967 175 0.012
localization of cell GO:0051674 202 0.012
cytokine production GO:0001816 61 0.012
regulation of locomotion GO:0040012 148 0.012
peptidyl amino acid modification GO:0018193 126 0.012
regulation of growth GO:0040008 105 0.012
cytokine biosynthetic process GO:0042089 3 0.012
protein oligomerization GO:0051259 191 0.012
cellular response to lipid GO:0071396 201 0.012
regulation of ion homeostasis GO:2000021 63 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
dna metabolic process GO:0006259 96 0.012
nuclear transport GO:0051169 49 0.012
regulation of secretion GO:0051046 224 0.012
organic acid transport GO:0015849 116 0.012
positive regulation of cellular amine metabolic process GO:0033240 3 0.012
cellular component biogenesis GO:0044085 368 0.011
regulation of peptide secretion GO:0002791 82 0.011
lymphocyte activation GO:0046649 43 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
organelle organization GO:0006996 266 0.011
protein transport GO:0015031 132 0.011
establishment of protein localization GO:0045184 141 0.011
activation of protein kinase activity GO:0032147 47 0.011
axonogenesis GO:0007409 71 0.011
female sex differentiation GO:0046660 59 0.011
cell growth GO:0016049 104 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
amide transport GO:0042886 105 0.011
regulation of vesicle mediated transport GO:0060627 81 0.011
positive regulation of immunoglobulin production GO:0002639 4 0.011
isoprenoid metabolic process GO:0006720 45 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
regulation of phosphate metabolic process GO:0019220 349 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
peptide transport GO:0015833 97 0.011
chemotaxis GO:0006935 66 0.011
single organism carbohydrate metabolic process GO:0044723 118 0.011
protein import into nucleus GO:0006606 35 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
mesoderm development GO:0007498 2 0.011
cellular response to oxygen levels GO:0071453 60 0.010
negative regulation of signal transduction GO:0009968 83 0.010
gonad development GO:0008406 104 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.010
ras protein signal transduction GO:0007265 29 0.010
protein complex subunit organization GO:0071822 302 0.010
response to ionizing radiation GO:0010212 59 0.010
retinoid metabolic process GO:0001523 24 0.010
protein localization to nucleus GO:0034504 39 0.010
reproduction GO:0000003 245 0.010
icosanoid metabolic process GO:0006690 38 0.010

Lrrc38 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
nervous system disease DOID:863 0 0.045
sensory system disease DOID:0050155 0 0.025
eye and adnexa disease DOID:1492 0 0.017
musculoskeletal system disease DOID:17 0 0.010