Rattus norvegicus

46 known processes

Slco4a1

solute carrier organic anion transporter family, member 4a1

(Aliases: Slc21a12,OATP-E)

Slco4a1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
vesicle mediated transport GO:0016192 181 0.156
head development GO:0060322 247 0.084
cation transmembrane transport GO:0098655 263 0.081
response to purine containing compound GO:0014074 126 0.077
organic acid transport GO:0015849 116 0.069
organophosphate metabolic process GO:0019637 370 0.067
monosaccharide metabolic process GO:0005996 61 0.062
response to camp GO:0051591 91 0.060
cellular component assembly GO:0022607 360 0.055
synaptic transmission GO:0007268 235 0.055
transmembrane transport GO:0055085 412 0.052
cellular response to oxygen containing compound GO:1901701 386 0.045
central nervous system development GO:0007417 311 0.045
neurological system process GO:0050877 219 0.045
chemical homeostasis GO:0048878 292 0.044
neuron differentiation GO:0030182 368 0.041
c21 steroid hormone biosynthetic process GO:0006700 10 0.040
protein complex biogenesis GO:0070271 263 0.040
cellular response to endogenous stimulus GO:0071495 377 0.038
cellular response to lipid GO:0071396 201 0.038
positive regulation of transport GO:0051050 245 0.038
cellular homeostasis GO:0019725 252 0.038
regulation of exocytosis GO:0017157 37 0.037
regulation of cellular ketone metabolic process GO:0010565 27 0.035
cellular ketone metabolic process GO:0042180 51 0.035
homeostatic process GO:0042592 331 0.034
protein complex assembly GO:0006461 263 0.034
oxoacid metabolic process GO:0043436 290 0.033
response to acid chemical GO:0001101 222 0.032
carboxylic acid transport GO:0046942 115 0.032
eye morphogenesis GO:0048592 4 0.032
single organism biosynthetic process GO:0044711 342 0.031
regulation of signal transduction GO:0009966 318 0.031
anatomical structure morphogenesis GO:0009653 298 0.031
organic acid metabolic process GO:0006082 292 0.031
macromolecular complex assembly GO:0065003 273 0.031
cellular chemical homeostasis GO:0055082 247 0.030
regulation of secretion GO:0051046 224 0.030
cellular lipid metabolic process GO:0044255 208 0.030
positive regulation of cell communication GO:0010647 271 0.030
cation transport GO:0006812 382 0.029
negative regulation of neuron differentiation GO:0045665 62 0.029
positive regulation of secretion GO:0051047 140 0.029
regulation of cellular component organization GO:0051128 368 0.029
nucleobase containing small molecule metabolic process GO:0055086 316 0.028
carbohydrate derivative metabolic process GO:1901135 346 0.028
organic anion transport GO:0015711 132 0.027
response to organophosphorus GO:0046683 102 0.027
positive regulation of rna metabolic process GO:0051254 203 0.027
regulation of cellular localization GO:0060341 263 0.027
anterior posterior pattern specification GO:0009952 1 0.027
cellular component biogenesis GO:0044085 368 0.026
response to monosaccharide GO:0034284 159 0.026
macromolecule localization GO:0033036 252 0.026
Rat
regulation of nucleic acid templated transcription GO:1903506 380 0.026
forebrain development GO:0030900 98 0.025
aging GO:0007568 241 0.024
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.024
regulation of secretion by cell GO:1903530 208 0.024
carboxylic acid metabolic process GO:0019752 289 0.023
positive regulation of secretion by cell GO:1903532 128 0.023
reproductive process GO:0022414 372 0.023
nucleotide metabolic process GO:0009117 279 0.022
small molecule biosynthetic process GO:0044283 124 0.022
hormone transport GO:0009914 121 0.022
single organism organelle organization GO:1902589 180 0.022
protein complex subunit organization GO:0071822 302 0.022
regulation of vesicle mediated transport GO:0060627 81 0.022
organic substance catabolic process GO:1901575 316 0.022
anion transport GO:0006820 178 0.022
response to glucose GO:0009749 136 0.022
brain development GO:0007420 247 0.022
phototransduction visible light GO:0007603 2 0.021
catabolic process GO:0009056 351 0.021
multi organism reproductive process GO:0044703 262 0.021
amine metabolic process GO:0009308 38 0.021
cell motility GO:0048870 202 0.021
positive regulation of phosphate metabolic process GO:0045937 262 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
peptide transport GO:0015833 97 0.020
Rat
programmed cell death GO:0012501 392 0.020
secretion by cell GO:0032940 248 0.020
protein oligomerization GO:0051259 191 0.020
alcohol metabolic process GO:0006066 77 0.020
exocytosis GO:0006887 60 0.019
neuron development GO:0048666 286 0.019
protein localization GO:0008104 191 0.019
cardiovascular system development GO:0072358 134 0.019
regulation of transcription dna templated GO:0006355 374 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.019
cellular amine metabolic process GO:0044106 38 0.019
cellular hormone metabolic process GO:0034754 49 0.019
regulation of multicellular organismal development GO:2000026 376 0.018
cellular calcium ion homeostasis GO:0006874 160 0.018
positive regulation of gene expression GO:0010628 244 0.018
single organism carbohydrate metabolic process GO:0044723 118 0.018
single organism catabolic process GO:0044712 283 0.018
cellular response to acid chemical GO:0071229 75 0.018
rna biosynthetic process GO:0032774 380 0.018
cellular catabolic process GO:0044248 295 0.018
anion transmembrane transport GO:0098656 77 0.018
response to growth factor GO:0070848 189 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
cell cell signaling GO:0007267 335 0.017
ion transmembrane transport GO:0034220 365 0.017
motor neuron axon guidance GO:0008045 1 0.017
tissue development GO:0009888 252 0.017
regulation of hormone levels GO:0010817 187 0.017
retina morphogenesis in camera type eye GO:0060042 1 0.017
regulation of lymphocyte migration GO:2000401 1 0.017
organelle organization GO:0006996 266 0.017
macromolecular complex subunit organization GO:0043933 339 0.017
negative regulation of nervous system development GO:0051961 79 0.017
positive regulation of molecular function GO:0044093 230 0.017
c21 steroid hormone metabolic process GO:0008207 14 0.017
neuron projection development GO:0031175 273 0.017
sensory perception GO:0007600 101 0.017
monocarboxylic acid metabolic process GO:0032787 152 0.016
cell cycle GO:0007049 101 0.016
sexual reproduction GO:0019953 148 0.016
lymphocyte chemotaxis GO:0048247 3 0.016
organic hydroxy compound metabolic process GO:1901615 115 0.016
cellular response to growth factor stimulus GO:0071363 162 0.016
regulation of calcium ion dependent exocytosis GO:0017158 11 0.016
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.016
response to extracellular stimulus GO:0009991 380 0.016
response to insulin GO:0032868 133 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
secretion GO:0046903 307 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.016
cellular response to alcohol GO:0097306 87 0.016
camera type eye morphogenesis GO:0048593 2 0.015
dephosphorylation GO:0016311 98 0.015
divalent inorganic cation transport GO:0072511 134 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
regulation of rna metabolic process GO:0051252 391 0.014
cellular response to organic cyclic compound GO:0071407 202 0.014
regulation of phosphorylation GO:0042325 248 0.014
neuromuscular synaptic transmission GO:0007274 2 0.014
metal ion transport GO:0030001 289 0.014
regulation of cell proliferation GO:0042127 359 0.014
lipid metabolic process GO:0006629 283 0.014
cell migration GO:0016477 197 0.014
behavior GO:0007610 205 0.014
negative regulation of cell development GO:0010721 82 0.014
response to carbohydrate GO:0009743 183 0.014
regulation of immune system process GO:0002682 123 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
cation homeostasis GO:0055080 195 0.014
cellular response to steroid hormone stimulus GO:0071383 93 0.014
response to osmotic stress GO:0006970 42 0.014
response to corticosteroid GO:0031960 235 0.013
Rat
hexose metabolic process GO:0019318 58 0.013
cell projection organization GO:0030030 302 0.013
cellular response to stress GO:0033554 269 0.013
single organism reproductive process GO:0044702 297 0.013
regulation of cell cycle GO:0051726 73 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
regulation of ion transport GO:0043269 245 0.013
regulation of cellular amino acid metabolic process GO:0006521 2 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
axis specification GO:0009798 4 0.013
synaptic growth at neuromuscular junction GO:0051124 1 0.013
locomotion GO:0040011 237 0.013
developmental process involved in reproduction GO:0003006 159 0.013
gastrulation GO:0007369 2 0.013
rna metabolic process GO:0016070 406 0.013
negative regulation of transport GO:0051051 136 0.013
cellular component movement GO:0006928 248 0.013
regulation of rna biosynthetic process GO:2001141 381 0.013
carbohydrate metabolic process GO:0005975 130 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.012
purine containing compound metabolic process GO:0072521 253 0.012
circulatory system development GO:0072359 134 0.012
transcription dna templated GO:0006351 377 0.012
cellular response to extracellular stimulus GO:0031668 73 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
nucleoside phosphate metabolic process GO:0006753 283 0.012
monocarboxylic acid transport GO:0015718 52 0.012
Rat
reproduction GO:0000003 245 0.012
progesterone biosynthetic process GO:0006701 3 0.012
lymphocyte migration GO:0072676 3 0.012
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.012
modified amino acid transport GO:0072337 12 0.012
regulation of cellular component biogenesis GO:0044087 86 0.012
transcription from rna polymerase ii promoter GO:0006366 252 0.012
regulation of phosphorus metabolic process GO:0051174 349 0.012
endoplasmic reticulum organization GO:0007029 1 0.012
response to ketone GO:1901654 182 0.012
vascular process in circulatory system GO:0003018 96 0.012
regulation of cell differentiation GO:0045595 320 0.012
response to nutrient levels GO:0031667 370 0.012
response to metal ion GO:0010038 253 0.012
response to hexose GO:0009746 144 0.012
amide transport GO:0042886 105 0.011
Rat
learning or memory GO:0007611 90 0.011
cognition GO:0050890 92 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
multicellular organism growth GO:0035264 1 0.011
cellular response to peptide GO:1901653 133 0.011
intracellular signal transduction GO:0035556 314 0.011
positive regulation of transcription dna templated GO:0045893 197 0.011
organic hydroxy compound biosynthetic process GO:1901617 51 0.011
carbohydrate biosynthetic process GO:0016051 42 0.011
sensory organ development GO:0007423 74 0.011
negative regulation of innate immune response GO:0045824 4 0.011
regulation of synaptic transmission GO:0050804 141 0.011
signal release GO:0023061 145 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
cellular protein localization GO:0034613 122 0.011
protein homooligomerization GO:0051260 91 0.011
regulation of peptide hormone secretion GO:0090276 80 0.011
locomotor rhythm GO:0045475 1 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
calcium ion homeostasis GO:0055074 162 0.011
protein phosphorylation GO:0006468 345 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
spermatogenesis GO:0007283 99 0.011
gamete generation GO:0007276 124 0.011
positive regulation of cellular component organization GO:0051130 200 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
regulation of metal ion transport GO:0010959 118 0.011
mapk cascade GO:0000165 140 0.010
insulin secretion GO:0030073 69 0.010
membrane fusion GO:0061025 26 0.010
multicellular organismal reproductive process GO:0048609 233 0.010
lipid storage GO:0019915 1 0.010
cellular macromolecule localization GO:0070727 122 0.010
negative regulation of cellular component organization GO:0051129 83 0.010
adult locomotory behavior GO:0008344 4 0.010
response to hypoxia GO:0001666 231 0.010
telencephalon development GO:0021537 62 0.010
single organism carbohydrate catabolic process GO:0044724 40 0.010
ribonucleotide metabolic process GO:0009259 231 0.010
regulation of catabolic process GO:0009894 113 0.010
nucleoside metabolic process GO:0009116 179 0.010
negative regulation of protein metabolic process GO:0051248 114 0.010
choline transport GO:0015871 4 0.010
regulation of insulin secretion GO:0050796 65 0.010
cellular ion homeostasis GO:0006873 184 0.010
detection of visible light GO:0009584 3 0.010
positive regulation of response to stimulus GO:0048584 285 0.010

Slco4a1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
retinal disease DOID:5679 0 0.198
retinal degeneration DOID:8466 0 0.198
sensory system disease DOID:0050155 0 0.198
disease of anatomical entity DOID:7 0 0.198
retinitis pigmentosa DOID:10584 0 0.198
eye and adnexa disease DOID:1492 0 0.198
nervous system disease DOID:863 0 0.198
eye disease DOID:5614 0 0.198
cone rod dystrophy DOID:0050572 0 0.080
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.012
central nervous system disease DOID:331 0 0.011
night blindness DOID:8499 0 0.011
congenital stationary night blindness DOID:0050534 0 0.011
primary immunodeficiency disease DOID:612 0 0.011
immune system disease DOID:2914 0 0.011