Rattus norvegicus

0 known processes

Otub2

OTU domain, ubiquitin aldehyde binding 2

Otub2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 292 0.108
oxoacid metabolic process GO:0043436 290 0.094
carboxylic acid metabolic process GO:0019752 289 0.077
central nervous system development GO:0007417 311 0.060
protein phosphorylation GO:0006468 345 0.055
head development GO:0060322 247 0.054
response to extracellular stimulus GO:0009991 380 0.054
organelle organization GO:0006996 266 0.052
cell projection organization GO:0030030 302 0.049
regulation of nucleic acid templated transcription GO:1903506 380 0.049
response to nutrient GO:0007584 248 0.047
neuron development GO:0048666 286 0.045
cellular amino acid metabolic process GO:0006520 107 0.045
brain development GO:0007420 247 0.044
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.043
nucleic acid templated transcription GO:0097659 379 0.041
cellular response to nitrogen compound GO:1901699 210 0.041
response to nutrient levels GO:0031667 370 0.041
rna biosynthetic process GO:0032774 380 0.041
rna metabolic process GO:0016070 406 0.041
regulation of transcription dna templated GO:0006355 374 0.040
negative regulation of cellular metabolic process GO:0031324 281 0.039
regulation of rna biosynthetic process GO:2001141 381 0.038
cellular amine metabolic process GO:0044106 38 0.038
positive regulation of cellular biosynthetic process GO:0031328 295 0.037
organophosphate metabolic process GO:0019637 370 0.036
regulation of neurogenesis GO:0050767 247 0.035
positive regulation of developmental process GO:0051094 283 0.035
single organism biosynthetic process GO:0044711 342 0.035
cellular component biogenesis GO:0044085 368 0.035
protein complex assembly GO:0006461 263 0.035
regulation of cellular amine metabolic process GO:0033238 8 0.035
response to vitamin GO:0033273 131 0.034
programmed cell death GO:0012501 392 0.034
regulation of cell development GO:0060284 263 0.033
negative regulation of macromolecule metabolic process GO:0010605 260 0.032
nucleobase containing small molecule metabolic process GO:0055086 316 0.031
multi organism reproductive process GO:0044703 262 0.031
regulation of programmed cell death GO:0043067 341 0.031
regulation of cellular amino acid metabolic process GO:0006521 2 0.031
catabolic process GO:0009056 351 0.031
regulation of cellular component organization GO:0051128 368 0.031
positive regulation of phosphorus metabolic process GO:0010562 262 0.030
protein complex biogenesis GO:0070271 263 0.029
negative regulation of metabolic process GO:0009892 331 0.029
cellular component assembly GO:0022607 360 0.029
amine metabolic process GO:0009308 38 0.029
regulation of phosphate metabolic process GO:0019220 349 0.029
reproductive process GO:0022414 372 0.029
neuron differentiation GO:0030182 368 0.028
regulation of protein modification process GO:0031399 194 0.028
regulation of signal transduction GO:0009966 318 0.028
transcription dna templated GO:0006351 377 0.028
carbohydrate derivative metabolic process GO:1901135 346 0.028
cellular ketone metabolic process GO:0042180 51 0.028
positive regulation of cell communication GO:0010647 271 0.027
regulation of cell differentiation GO:0045595 320 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.027
macromolecular complex subunit organization GO:0043933 339 0.027
regulation of rna metabolic process GO:0051252 391 0.026
regulation of membrane potential GO:0042391 110 0.026
positive regulation of catalytic activity GO:0043085 184 0.026
ribonucleotide metabolic process GO:0009259 231 0.026
nucleoside phosphate metabolic process GO:0006753 283 0.026
apoptotic process GO:0006915 381 0.026
positive regulation of protein metabolic process GO:0051247 178 0.025
organophosphate biosynthetic process GO:0090407 143 0.025
positive regulation of cellular protein metabolic process GO:0032270 167 0.025
positive regulation of cell differentiation GO:0045597 217 0.025
circadian rhythm GO:0007623 88 0.025
positive regulation of phosphate metabolic process GO:0045937 262 0.025
ribose phosphate metabolic process GO:0019693 235 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.024
cellular component movement GO:0006928 248 0.024
positive regulation of biosynthetic process GO:0009891 319 0.024
positive regulation of multicellular organismal process GO:0051240 387 0.024
transcription from rna polymerase ii promoter GO:0006366 252 0.024
regulation of cell projection organization GO:0031344 175 0.024
monocarboxylic acid metabolic process GO:0032787 152 0.024
purine ribonucleotide metabolic process GO:0009150 227 0.024
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.023
reproduction GO:0000003 245 0.023
response to estradiol GO:0032355 164 0.023
regulation of apoptotic process GO:0042981 335 0.023
response to peptide GO:1901652 292 0.023
intracellular signal transduction GO:0035556 314 0.023
aging GO:0007568 241 0.023
regulation of hormone levels GO:0010817 187 0.023
purine nucleotide metabolic process GO:0006163 229 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
regulation of catalytic activity GO:0050790 304 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.022
negative regulation of multicellular organismal process GO:0051241 203 0.021
organonitrogen compound biosynthetic process GO:1901566 167 0.021
macromolecular complex assembly GO:0065003 273 0.021
cellular response to oxygen containing compound GO:1901701 386 0.021
regulation of protein metabolic process GO:0051246 289 0.021
protein complex subunit organization GO:0071822 302 0.021
cellular lipid metabolic process GO:0044255 208 0.021
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.020
purine containing compound metabolic process GO:0072521 253 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.020
positive regulation of signaling GO:0023056 270 0.020
negative regulation of biosynthetic process GO:0009890 168 0.020
positive regulation of nervous system development GO:0051962 178 0.019
organic substance catabolic process GO:1901575 316 0.019
response to acid chemical GO:0001101 222 0.019
response to metal ion GO:0010038 253 0.019
negative regulation of gene expression GO:0010629 199 0.019
regulation of nervous system development GO:0051960 264 0.019
cytoplasmic transport GO:0016482 115 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
cellular response to organonitrogen compound GO:0071417 197 0.019
carbohydrate metabolic process GO:0005975 130 0.019
positive regulation of neurogenesis GO:0050769 165 0.019
lipid biosynthetic process GO:0008610 128 0.019
positive regulation of molecular function GO:0044093 230 0.018
negative regulation of nucleic acid templated transcription GO:1903507 117 0.018
cation transport GO:0006812 382 0.018
response to ethanol GO:0045471 162 0.018
regulation of multicellular organismal development GO:2000026 376 0.018
regulation of cell proliferation GO:0042127 359 0.018
regulation of locomotion GO:0040012 148 0.018
secretion GO:0046903 307 0.018
positive regulation of programmed cell death GO:0043068 157 0.018
regulation of transferase activity GO:0051338 123 0.018
negative regulation of signaling GO:0023057 157 0.018
rhythmic process GO:0048511 156 0.018
cellular nitrogen compound catabolic process GO:0044270 163 0.018
regulation of neuron differentiation GO:0045664 208 0.018
positive regulation of protein modification process GO:0031401 142 0.017
cellular component morphogenesis GO:0032989 155 0.017
actin filament based process GO:0030029 86 0.017
regulation of protein phosphorylation GO:0001932 183 0.017
regulation of cell cycle GO:0051726 73 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
response to inorganic substance GO:0010035 377 0.017
regulation of system process GO:0044057 208 0.017
nucleotide metabolic process GO:0009117 279 0.017
cellular catabolic process GO:0044248 295 0.017
organic acid transport GO:0015849 116 0.017
organic hydroxy compound metabolic process GO:1901615 115 0.017
regulation of molecular function GO:0065009 398 0.017
heterocycle catabolic process GO:0046700 167 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
protein oligomerization GO:0051259 191 0.016
tissue development GO:0009888 252 0.016
regulation of purine nucleotide metabolic process GO:1900542 115 0.016
response to decreased oxygen levels GO:0036293 237 0.016
regulation of phosphorus metabolic process GO:0051174 349 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
single organism organelle organization GO:1902589 180 0.016
sexual reproduction GO:0019953 148 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
lipid metabolic process GO:0006629 283 0.016
positive regulation of cellular component organization GO:0051130 200 0.016
nucleobase containing compound catabolic process GO:0034655 152 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
actin cytoskeleton organization GO:0030036 73 0.015
regulation of cellular protein metabolic process GO:0032268 267 0.015
single organism carbohydrate metabolic process GO:0044723 118 0.015
negative regulation of cell death GO:0060548 229 0.015
carboxylic acid biosynthetic process GO:0046394 83 0.015
multicellular organismal reproductive process GO:0048609 233 0.015
cell cycle GO:0007049 101 0.015
ribonucleoside triphosphate metabolic process GO:0009199 141 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
multicellular organism growth GO:0035264 1 0.015
negative regulation of cellular biosynthetic process GO:0031327 161 0.015
single organism catabolic process GO:0044712 283 0.014
response to oxygen levels GO:0070482 265 0.014
positive regulation of rna metabolic process GO:0051254 203 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
nucleoside metabolic process GO:0009116 179 0.014
regulation of neuron projection development GO:0010975 161 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
intracellular transport GO:0046907 185 0.014
anterior posterior pattern specification GO:0009952 1 0.014
small molecule biosynthetic process GO:0044283 124 0.014
regulation of phosphorylation GO:0042325 248 0.014
cell part morphogenesis GO:0032990 123 0.014
positive regulation of nucleic acid templated transcription GO:1903508 197 0.014
neuron projection development GO:0031175 273 0.014
positive regulation of cell proliferation GO:0008284 249 0.013
homeostatic process GO:0042592 331 0.013
multi multicellular organism process GO:0044706 138 0.013
protein localization GO:0008104 191 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
response to peptide hormone GO:0043434 278 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
nucleoside phosphate biosynthetic process GO:1901293 102 0.013
proteolysis GO:0006508 175 0.013
Human
response to hypoxia GO:0001666 231 0.013
ion transmembrane transport GO:0034220 365 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
regulation of anatomical structure size GO:0090066 135 0.013
positive regulation of transferase activity GO:0051347 81 0.013
cyclic nucleotide metabolic process GO:0009187 80 0.013
response to insulin GO:0032868 133 0.012
alpha amino acid metabolic process GO:1901605 71 0.012
establishment of protein localization GO:0045184 141 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
response to estrogen GO:0043627 232 0.012
positive regulation of cell development GO:0010720 176 0.012
single organism behavior GO:0044708 130 0.012
growth GO:0040007 165 0.012
organic acid biosynthetic process GO:0016053 83 0.012
cellular protein localization GO:0034613 122 0.012
axis specification GO:0009798 4 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
nucleotide catabolic process GO:0009166 139 0.012
positive regulation of cell death GO:0010942 184 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
organophosphate catabolic process GO:0046434 148 0.012
cell cell signaling GO:0007267 335 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.012
negative regulation of cell communication GO:0010648 158 0.012
cellular response to peptide GO:1901653 133 0.012
cellular homeostasis GO:0019725 252 0.012
cellular amide metabolic process GO:0043603 44 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
response to growth factor GO:0070848 189 0.012
metal ion transport GO:0030001 289 0.012
positive regulation of gene expression GO:0010628 244 0.012
multicellular organism reproduction GO:0032504 233 0.012
nucleoside triphosphate metabolic process GO:0009141 144 0.011
positive regulation of nucleotide metabolic process GO:0045981 91 0.011
synaptic transmission GO:0007268 235 0.011
regulation of cellular localization GO:0060341 263 0.011
cellular macromolecule localization GO:0070727 122 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
retina morphogenesis in camera type eye GO:0060042 1 0.011
protein localization to organelle GO:0033365 57 0.011
transmembrane transport GO:0055085 412 0.011
chemical homeostasis GO:0048878 292 0.011
regulation of intracellular transport GO:0032386 65 0.011
neuron projection morphogenesis GO:0048812 122 0.011
regulation of secretion GO:0051046 224 0.011
cell morphogenesis GO:0000902 142 0.011
positive regulation of response to stimulus GO:0048584 285 0.011
neuronal action potential GO:0019228 35 0.011
cell growth GO:0016049 104 0.011
negative regulation of stress activated protein kinase signaling cascade GO:0070303 4 0.011
single organism reproductive process GO:0044702 297 0.011
single organism intracellular transport GO:1902582 166 0.011
nucleoside monophosphate metabolic process GO:0009123 93 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
axon development GO:0061564 96 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
cytoskeleton organization GO:0007010 111 0.011
ribonucleoside monophosphate metabolic process GO:0009161 88 0.011
locomotion GO:0040011 237 0.011
cell cycle checkpoint GO:0000075 2 0.010
ribonucleoside metabolic process GO:0009119 174 0.010
nucleoside catabolic process GO:0009164 126 0.010
organic cyclic compound catabolic process GO:1901361 175 0.010
positive regulation of rna biosynthetic process GO:1902680 197 0.010
regulation of kinase activity GO:0043549 117 0.010
cellular response to stress GO:0033554 269 0.010
gamete generation GO:0007276 124 0.010
neurological system process GO:0050877 219 0.010
polysaccharide metabolic process GO:0005976 25 0.010
peptidyl amino acid modification GO:0018193 126 0.010
divalent inorganic cation homeostasis GO:0072507 165 0.010
monocarboxylic acid biosynthetic process GO:0072330 48 0.010
response to radiation GO:0009314 137 0.010

Otub2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016
disease of metabolism DOID:0014667 0 0.014
sensory system disease DOID:0050155 0 0.011