Rattus norvegicus

21 known processes

Kcnk10

potassium channel, subfamily K, member 10

(Aliases: TREK2)

Kcnk10 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 292 0.162
carboxylic acid metabolic process GO:0019752 289 0.158
positive regulation of cell communication GO:0010647 271 0.153
oxoacid metabolic process GO:0043436 290 0.113
single organism biosynthetic process GO:0044711 342 0.095
positive regulation of signaling GO:0023056 270 0.091
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.074
inorganic ion transmembrane transport GO:0098660 229 0.073
response to purine containing compound GO:0014074 126 0.061
establishment of vesicle localization GO:0051650 31 0.060
anatomical structure morphogenesis GO:0009653 298 0.060
catabolic process GO:0009056 351 0.060
rna biosynthetic process GO:0032774 380 0.059
homeostatic process GO:0042592 331 0.058
Rat
regulation of catalytic activity GO:0050790 304 0.057
response to peptide hormone GO:0043434 278 0.056
intracellular signal transduction GO:0035556 314 0.055
cell cell signaling GO:0007267 335 0.054
neuron development GO:0048666 286 0.052
lipid biosynthetic process GO:0008610 128 0.050
protein complex subunit organization GO:0071822 302 0.050
inorganic cation transmembrane transport GO:0098662 202 0.050
cellular catabolic process GO:0044248 295 0.049
response to peptide GO:1901652 292 0.049
regulation of phosphorus metabolic process GO:0051174 349 0.049
cellular amine metabolic process GO:0044106 38 0.048
amine metabolic process GO:0009308 38 0.048
single organism catabolic process GO:0044712 283 0.048
synaptic transmission GO:0007268 235 0.047
response to camp GO:0051591 91 0.047
synaptic growth at neuromuscular junction GO:0051124 1 0.046
cellular ketone metabolic process GO:0042180 51 0.044
regulation of cellular component organization GO:0051128 368 0.044
transmembrane transport GO:0055085 412 0.043
chemical homeostasis GO:0048878 292 0.043
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.043
neuron projection development GO:0031175 273 0.042
negative regulation of metabolic process GO:0009892 331 0.041
divalent inorganic cation homeostasis GO:0072507 165 0.040
Rat
response to corticosteroid GO:0031960 235 0.040
regulation of cellular amino acid metabolic process GO:0006521 2 0.040
lipid metabolic process GO:0006629 283 0.039
organic substance catabolic process GO:1901575 316 0.039
cellular amino acid metabolic process GO:0006520 107 0.038
cellular component assembly GO:0022607 360 0.037
positive regulation of cellular biosynthetic process GO:0031328 295 0.037
regulation of rna biosynthetic process GO:2001141 381 0.037
regulation of hormone levels GO:0010817 187 0.037
regulation of neuron projection development GO:0010975 161 0.037
cellular response to stress GO:0033554 269 0.037
Rat
regulation of cellular amine metabolic process GO:0033238 8 0.036
cell projection organization GO:0030030 302 0.036
regulation of protein modification process GO:0031399 194 0.035
regulation of molecular function GO:0065009 398 0.035
negative regulation of cellular biosynthetic process GO:0031327 161 0.033
behavior GO:0007610 205 0.033
Fly
cation transport GO:0006812 382 0.033
response to wounding GO:0009611 254 0.032
regulation of phosphorylation GO:0042325 248 0.032
aromatic compound catabolic process GO:0019439 168 0.032
response to glucocorticoid GO:0051384 223 0.032
regulation of cellular ketone metabolic process GO:0010565 27 0.032
nucleic acid templated transcription GO:0097659 379 0.032
hormone transport GO:0009914 121 0.031
secretion by cell GO:0032940 248 0.031
regulation of nervous system development GO:0051960 264 0.031
regulation of rna metabolic process GO:0051252 391 0.031
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.030
organic cyclic compound catabolic process GO:1901361 175 0.030
hormone secretion GO:0046879 115 0.030
secretion GO:0046903 307 0.030
peptidyl amino acid modification GO:0018193 126 0.029
response to axon injury GO:0048678 59 0.029
positive regulation of catalytic activity GO:0043085 184 0.028
positive regulation of biosynthetic process GO:0009891 319 0.028
nucleobase containing small molecule metabolic process GO:0055086 316 0.028
metal ion homeostasis GO:0055065 186 0.028
Rat
establishment of organelle localization GO:0051656 37 0.028
regulation of protein metabolic process GO:0051246 289 0.028
purine containing compound metabolic process GO:0072521 253 0.028
response to inorganic substance GO:0010035 377 0.027
Rat
regulation of nucleic acid templated transcription GO:1903506 380 0.027
defense response GO:0006952 194 0.027
response to acid chemical GO:0001101 222 0.027
heterocycle catabolic process GO:0046700 167 0.026
positive regulation of transferase activity GO:0051347 81 0.025
rna metabolic process GO:0016070 406 0.025
programmed cell death GO:0012501 392 0.025
monocarboxylic acid metabolic process GO:0032787 152 0.025
glycosyl compound metabolic process GO:1901657 182 0.025
response to toxic substance GO:0009636 133 0.025
organelle organization GO:0006996 266 0.025
negative regulation of transcription dna templated GO:0045892 116 0.025
regulation of transcription dna templated GO:0006355 374 0.025
axis specification GO:0009798 4 0.024
positive regulation of cellular component organization GO:0051130 200 0.024
transcription dna templated GO:0006351 377 0.024
vesicle localization GO:0051648 33 0.024
regulation of signal transduction GO:0009966 318 0.024
organic hydroxy compound metabolic process GO:1901615 115 0.023
mononuclear cell proliferation GO:0032943 29 0.023
regulation of transferase activity GO:0051338 123 0.023
neuron differentiation GO:0030182 368 0.023
neuron projection morphogenesis GO:0048812 122 0.023
carbohydrate derivative metabolic process GO:1901135 346 0.023
dicarboxylic acid transport GO:0006835 34 0.023
protein localization GO:0008104 191 0.023
protein phosphorylation GO:0006468 345 0.023
axonogenesis GO:0007409 71 0.022
regulation of cell development GO:0060284 263 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.022
synaptic vesicle localization GO:0097479 24 0.022
organelle localization GO:0051640 55 0.022
organonitrogen compound catabolic process GO:1901565 179 0.022
protein complex assembly GO:0006461 263 0.022
cellular component biogenesis GO:0044085 368 0.022
response to reactive oxygen species GO:0000302 120 0.022
developmental growth GO:0048589 100 0.022
response to growth factor GO:0070848 189 0.022
regulation of protein phosphorylation GO:0001932 183 0.021
central nervous system development GO:0007417 311 0.021
Rat
signal release GO:0023061 145 0.021
macromolecular complex subunit organization GO:0043933 339 0.021
negative regulation of transport GO:0051051 136 0.021
positive regulation of synaptic transmission GO:0050806 62 0.021
synaptic vesicle transport GO:0048489 23 0.021
positive regulation of gene expression GO:0010628 244 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
response to decreased oxygen levels GO:0036293 237 0.021
Rat
ribonucleotide metabolic process GO:0009259 231 0.021
positive regulation of neuron projection development GO:0010976 99 0.021
multi organism reproductive process GO:0044703 262 0.021
regulation of intracellular signal transduction GO:1902531 218 0.020
anion transport GO:0006820 178 0.020
positive regulation of response to stimulus GO:0048584 285 0.020
positive regulation of cell projection organization GO:0031346 111 0.020
regulation of cellular protein metabolic process GO:0032268 267 0.020
cation transmembrane transport GO:0098655 263 0.020
regulation of membrane potential GO:0042391 110 0.020
response to organophosphorus GO:0046683 102 0.020
cellular response to nitrogen compound GO:1901699 210 0.020
positive regulation of nucleic acid templated transcription GO:1903508 197 0.020
metal ion transport GO:0030001 289 0.020
response to ethanol GO:0045471 162 0.020
ribonucleoside triphosphate metabolic process GO:0009199 141 0.020
tissue development GO:0009888 252 0.020
negative regulation of macromolecule metabolic process GO:0010605 260 0.019
purine containing compound catabolic process GO:0072523 138 0.019
establishment of synaptic vesicle localization GO:0097480 23 0.019
response to nutrient levels GO:0031667 370 0.019
regulation of multicellular organismal development GO:2000026 376 0.019
regulation of phosphate metabolic process GO:0019220 349 0.019
regulation of blood pressure GO:0008217 83 0.019
phenol containing compound metabolic process GO:0018958 30 0.019
ribonucleoside metabolic process GO:0009119 174 0.019
brain development GO:0007420 247 0.019
Rat
carbohydrate metabolic process GO:0005975 130 0.019
regulation of protein kinase activity GO:0045859 105 0.019
gland development GO:0048732 155 0.019
vesicle mediated transport GO:0016192 181 0.019
response to ketone GO:1901654 182 0.019
negative regulation of cellular metabolic process GO:0031324 281 0.019
negative regulation of cell differentiation GO:0045596 99 0.018
cellular lipid metabolic process GO:0044255 208 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
purine nucleotide metabolic process GO:0006163 229 0.018
cellular response to external stimulus GO:0071496 118 0.018
purine nucleotide catabolic process GO:0006195 136 0.018
aging GO:0007568 241 0.018
head development GO:0060322 247 0.018
Rat
nucleotide catabolic process GO:0009166 139 0.018
cell projection morphogenesis GO:0048858 123 0.018
amide transport GO:0042886 105 0.017
reactive oxygen species metabolic process GO:0072593 37 0.017
purine nucleoside triphosphate catabolic process GO:0009146 122 0.017
positive regulation of phosphate metabolic process GO:0045937 262 0.017
ion homeostasis GO:0050801 212 0.017
Rat
negative regulation of nucleic acid templated transcription GO:1903507 117 0.017
regulation of cellular localization GO:0060341 263 0.017
nucleotide metabolic process GO:0009117 279 0.017
ribose phosphate metabolic process GO:0019693 235 0.017
positive regulation of rna metabolic process GO:0051254 203 0.017
regulation of cell differentiation GO:0045595 320 0.017
purine ribonucleoside metabolic process GO:0046128 168 0.017
fatty acid metabolic process GO:0006631 99 0.017
negative regulation of gene expression GO:0010629 199 0.016
organonitrogen compound biosynthetic process GO:1901566 167 0.016
cellular cation homeostasis GO:0030003 180 0.016
Rat
ribonucleotide catabolic process GO:0009261 136 0.016
positive regulation of molecular function GO:0044093 230 0.016
regulation of apoptotic process GO:0042981 335 0.016
regulation of programmed cell death GO:0043067 341 0.016
regulation of secretion by cell GO:1903530 208 0.016
regulation of neurogenesis GO:0050767 247 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
macromolecular complex assembly GO:0065003 273 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
cellular protein localization GO:0034613 122 0.016
nucleoside metabolic process GO:0009116 179 0.016
stress activated protein kinase signaling cascade GO:0031098 37 0.016
reactive nitrogen species metabolic process GO:2001057 1 0.016
purine ribonucleotide catabolic process GO:0009154 136 0.015
response to hexose GO:0009746 144 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
transcription from rna polymerase ii promoter GO:0006366 252 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
Rat
positive regulation of protein modification process GO:0031401 142 0.015
telencephalon development GO:0021537 62 0.015
organic acid transport GO:0015849 116 0.015
nitrogen compound transport GO:0071705 229 0.015
regulation of anatomical structure size GO:0090066 135 0.015
negative regulation of molecular function GO:0044092 133 0.015
apoptotic process GO:0006915 381 0.015
response to mechanical stimulus GO:0009612 134 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
purine nucleoside catabolic process GO:0006152 124 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.014
regulation of ion transmembrane transport GO:0034765 121 0.014
Rat
locomotion GO:0040011 237 0.014
regulation of synaptic transmission GO:0050804 141 0.014
single organism membrane organization GO:0044802 74 0.014
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
regulation of system process GO:0044057 208 0.014
Fly
reactive oxygen species biosynthetic process GO:1903409 8 0.014
nucleoside phosphate metabolic process GO:0006753 283 0.014
establishment of protein localization GO:0045184 141 0.014
regulation of peptide hormone secretion GO:0090276 80 0.014
protein transport GO:0015031 132 0.014
peptide hormone secretion GO:0030072 84 0.014
ion transmembrane transport GO:0034220 365 0.014
cellular macromolecule localization GO:0070727 122 0.014
negative regulation of secretion GO:0051048 82 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.014
regulation of peptide secretion GO:0002791 82 0.014
cellular homeostasis GO:0019725 252 0.014
Rat
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.014
cell part morphogenesis GO:0032990 123 0.014
cellular chemical homeostasis GO:0055082 247 0.014
Rat
positive regulation of secretion GO:0051047 140 0.014
regulation of secretion GO:0051046 224 0.014
cellular response to oxygen containing compound GO:1901701 386 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
neurological system process GO:0050877 219 0.013
neuromuscular process GO:0050905 2 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
regulation of neuron differentiation GO:0045664 208 0.013
positive regulation of cell death GO:0010942 184 0.013
developmental process involved in reproduction GO:0003006 159 0.013
g protein coupled receptor signaling pathway GO:0007186 242 0.013
actin filament bundle organization GO:0061572 19 0.013
neuron fate commitment GO:0048663 4 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
oxidation reduction process GO:0055114 304 0.013
nucleoside phosphate biosynthetic process GO:1901293 102 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
startle response GO:0001964 2 0.013
small molecule biosynthetic process GO:0044283 124 0.013
single organism cellular localization GO:1902580 102 0.013
response to metal ion GO:0010038 253 0.013
Rat
spinal cord development GO:0021510 27 0.012
response to hypoxia GO:0001666 231 0.012
Rat
ribonucleoside catabolic process GO:0042454 126 0.012
regulation of hormone secretion GO:0046883 106 0.012
response to amine GO:0014075 46 0.012
regulation of axonogenesis GO:0050770 37 0.012
reproductive process GO:0022414 372 0.012
response to extracellular stimulus GO:0009991 380 0.012
response to oxygen levels GO:0070482 265 0.012
Rat
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.012
response to glucose GO:0009749 136 0.012
positive regulation of secretion by cell GO:1903532 128 0.012
macromolecule localization GO:0033036 252 0.012
regulation of transmembrane transport GO:0034762 122 0.012
Rat
regulation of neuron death GO:1901214 115 0.012
vascular process in circulatory system GO:0003018 96 0.012
negative regulation of cell communication GO:0010648 158 0.012
regulation of cell growth GO:0001558 85 0.012
adult locomotory behavior GO:0008344 4 0.012
proteolysis GO:0006508 175 0.012
response to cytokine GO:0034097 215 0.012
alpha amino acid metabolic process GO:1901605 71 0.012
circadian rhythm GO:0007623 88 0.012
Fly
membrane organization GO:0061024 94 0.011
ras protein signal transduction GO:0007265 29 0.011
carboxylic acid transport GO:0046942 115 0.011
regulation of insulin secretion GO:0050796 65 0.011
positive regulation of kinase activity GO:0033674 77 0.011
regulation of kinase activity GO:0043549 117 0.011
regulation of cell projection organization GO:0031344 175 0.011
peptide transport GO:0015833 97 0.011
organophosphate catabolic process GO:0046434 148 0.011
regulation of peptide transport GO:0090087 87 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
neuropeptide signaling pathway GO:0007218 29 0.011
cellular ion homeostasis GO:0006873 184 0.011
Rat
negative regulation of cell death GO:0060548 229 0.011
cellular response to nutrient levels GO:0031669 60 0.011
single organism behavior GO:0044708 130 0.011
Fly
blood circulation GO:0008015 183 0.011
Fly
gliogenesis GO:0042063 93 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
organophosphate metabolic process GO:0019637 370 0.011
ribonucleoside triphosphate catabolic process GO:0009203 122 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
activation of mapkk activity GO:0000186 18 0.011
protein complex biogenesis GO:0070271 263 0.011
regulation of catabolic process GO:0009894 113 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.011
response to cocaine GO:0042220 39 0.011
positive regulation of catabolic process GO:0009896 78 0.011
response to insecticide GO:0017085 21 0.011
cell morphogenesis GO:0000902 142 0.011
muscle cell proliferation GO:0033002 84 0.010
intracellular protein transport GO:0006886 79 0.010
axon development GO:0061564 96 0.010
insulin secretion GO:0030073 69 0.010
forebrain development GO:0030900 98 0.010
serotonin metabolic process GO:0042428 3 0.010
ribonucleotide biosynthetic process GO:0009260 85 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
response to cadmium ion GO:0046686 35 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
cellular response to extracellular stimulus GO:0031668 73 0.010
response to starvation GO:0042594 59 0.010
intracellular receptor signaling pathway GO:0030522 35 0.010
regulation of lipid metabolic process GO:0019216 68 0.010
multicellular organismal response to stress GO:0033555 25 0.010
negative regulation of neuron death GO:1901215 69 0.010
lipid storage GO:0019915 1 0.010
cation homeostasis GO:0055080 195 0.010
Rat
protein oligomerization GO:0051259 191 0.010
isoprenoid metabolic process GO:0006720 45 0.010
regulation of cell migration GO:0030334 128 0.010

Kcnk10 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
central nervous system disease DOID:331 0 0.018
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.010