Rattus norvegicus

0 known processes

Tyrobp

Tyro protein tyrosine kinase binding protein

(Aliases: Karap)

Tyrobp biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
immune response GO:0006955 104 0.526
granulocyte chemotaxis GO:0071621 15 0.479
regulation of leukocyte chemotaxis GO:0002688 12 0.234
positive regulation of multicellular organismal process GO:0051240 387 0.225
immune system process GO:0002376 204 0.221
defense response GO:0006952 194 0.192
ion homeostasis GO:0050801 212 0.174
divalent inorganic cation homeostasis GO:0072507 165 0.161
homeostatic process GO:0042592 331 0.143
establishment of protein localization GO:0045184 141 0.127
cellular cation homeostasis GO:0030003 180 0.125
calcium ion homeostasis GO:0055074 162 0.124
cellular chemical homeostasis GO:0055082 247 0.122
cation transport GO:0006812 382 0.109
positive regulation of neutrophil chemotaxis GO:0090023 5 0.106
regulation of cell proliferation GO:0042127 359 0.106
cell activation GO:0001775 97 0.104
positive regulation of response to stimulus GO:0048584 285 0.102
response to ddt GO:0046680 1 0.097
protein complex subunit organization GO:0071822 302 0.095
regulation of cell differentiation GO:0045595 320 0.095
cellular metal ion homeostasis GO:0006875 172 0.094
positive regulation of signaling GO:0023056 270 0.092
hematopoietic progenitor cell differentiation GO:0002244 2 0.090
brain development GO:0007420 247 0.090
cellular divalent inorganic cation homeostasis GO:0072503 162 0.090
chemical homeostasis GO:0048878 292 0.086
carboxylic acid metabolic process GO:0019752 289 0.083
intracellular signal transduction GO:0035556 314 0.081
cation homeostasis GO:0055080 195 0.081
leukocyte cell cell adhesion GO:0007159 4 0.077
neurological system process GO:0050877 219 0.077
immune effector process GO:0002252 53 0.076
regulation of intracellular signal transduction GO:1902531 218 0.071
cellular calcium ion homeostasis GO:0006874 160 0.071
single organism organelle organization GO:1902589 180 0.069
macromolecular complex subunit organization GO:0043933 339 0.068
regulation of anatomical structure morphogenesis GO:0022603 141 0.067
cellular component assembly GO:0022607 360 0.066
regulation of cellular amino acid metabolic process GO:0006521 2 0.065
cellular component biogenesis GO:0044085 368 0.064
cell migration GO:0016477 197 0.063
cellular homeostasis GO:0019725 252 0.062
positive regulation of leukocyte migration GO:0002687 21 0.062
regulation of phosphorus metabolic process GO:0051174 349 0.056
anatomical structure morphogenesis GO:0009653 298 0.056
actin filament based process GO:0030029 86 0.055
positive regulation of cellular component organization GO:0051130 200 0.055
cellular ion homeostasis GO:0006873 184 0.054
positive regulation of intracellular signal transduction GO:1902533 138 0.052
response to biotic stimulus GO:0009607 226 0.051
protein phosphorylation GO:0006468 345 0.050
response to external biotic stimulus GO:0043207 221 0.048
metal ion homeostasis GO:0055065 186 0.047
myeloid leukocyte differentiation GO:0002573 20 0.047
insecticide metabolic process GO:0017143 4 0.046
rna metabolic process GO:0016070 406 0.046
metal ion transport GO:0030001 289 0.046
regulation of immune system process GO:0002682 123 0.046
cellular amine metabolic process GO:0044106 38 0.044
nucleic acid templated transcription GO:0097659 379 0.043
actin cytoskeleton organization GO:0030036 73 0.043
granulocyte migration GO:0097530 16 0.043
regulation of cellular component organization GO:0051128 368 0.042
response to decreased oxygen levels GO:0036293 237 0.041
negative regulation of cellular biosynthetic process GO:0031327 161 0.041
regulation of ion transport GO:0043269 245 0.041
regulation of phosphorylation GO:0042325 248 0.040
vesicle mediated transport GO:0016192 181 0.040
positive regulation of immune system process GO:0002684 90 0.040
positive regulation of phosphorus metabolic process GO:0010562 262 0.040
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.039
leukocyte activation GO:0045321 76 0.039
cellular response to lipopolysaccharide GO:0071222 55 0.038
triglyceride homeostasis GO:0070328 2 0.038
regulation of rna biosynthetic process GO:2001141 381 0.038
regulation of neuron apoptotic process GO:0043523 83 0.038
amine metabolic process GO:0009308 38 0.037
regulation of protein metabolic process GO:0051246 289 0.037
positive regulation of phosphate metabolic process GO:0045937 262 0.036
neuron death GO:0070997 127 0.036
regulation of molecular function GO:0065009 398 0.036
regulation of cellular amine metabolic process GO:0033238 8 0.036
cellular component movement GO:0006928 248 0.036
anterior posterior pattern specification GO:0009952 1 0.035
programmed cell death GO:0012501 392 0.035
response to transition metal nanoparticle GO:1990267 122 0.034
positive regulation of cell communication GO:0010647 271 0.034
regulation of transcription dna templated GO:0006355 374 0.034
cell projection organization GO:0030030 302 0.034
sensory perception GO:0007600 101 0.034
ribose phosphate metabolic process GO:0019693 235 0.033
positive regulation of cell differentiation GO:0045597 217 0.033
nucleotide metabolic process GO:0009117 279 0.033
positive regulation of protein phosphorylation GO:0001934 135 0.033
regulation of cellular component biogenesis GO:0044087 86 0.033
positive regulation of mapk cascade GO:0043410 92 0.033
regulation of cellular localization GO:0060341 263 0.033
actin cytoskeleton reorganization GO:0031532 8 0.032
protein transport GO:0015031 132 0.032
positive regulation of leukocyte chemotaxis GO:0002690 10 0.032
single organism cell adhesion GO:0098602 46 0.032
regulation of rna metabolic process GO:0051252 391 0.032
regulation of cell migration GO:0030334 128 0.032
organophosphate metabolic process GO:0019637 370 0.031
protein localization GO:0008104 191 0.031
regulation of b cell differentiation GO:0045577 1 0.031
aging GO:0007568 241 0.031
positive regulation of phosphorylation GO:0042327 177 0.031
cytoskeleton organization GO:0007010 111 0.031
purine ribonucleoside metabolic process GO:0046128 168 0.030
negative regulation of developmental process GO:0051093 125 0.030
divalent metal ion transport GO:0070838 132 0.029
response to other organism GO:0051707 220 0.029
cellular response to growth factor stimulus GO:0071363 162 0.029
reactive oxygen species metabolic process GO:0072593 37 0.029
regulation of locomotion GO:0040012 148 0.028
mapk cascade GO:0000165 140 0.028
cellular amino acid metabolic process GO:0006520 107 0.028
response to hypoxia GO:0001666 231 0.028
salivary gland development GO:0007431 3 0.028
negative regulation of cell development GO:0010721 82 0.028
locomotion GO:0040011 237 0.027
regulation of neutrophil migration GO:1902622 6 0.027
apoptotic process GO:0006915 381 0.027
macromolecule localization GO:0033036 252 0.027
regulation of signal transduction GO:0009966 318 0.027
regulation of apoptotic process GO:0042981 335 0.027
negative regulation of nervous system development GO:0051961 79 0.026
lymphoid progenitor cell differentiation GO:0002320 2 0.026
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.026
cell type specific apoptotic process GO:0097285 134 0.026
organelle organization GO:0006996 266 0.026
chemotaxis GO:0006935 66 0.026
positive regulation of cell migration GO:0030335 96 0.026
cell morphogenesis GO:0000902 142 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.026
regulation of nervous system development GO:0051960 264 0.025
positive regulation of biosynthetic process GO:0009891 319 0.025
negative regulation of biosynthetic process GO:0009890 168 0.025
guanosine containing compound metabolic process GO:1901068 74 0.025
central nervous system development GO:0007417 311 0.025
response to yeast GO:0001878 3 0.025
negative regulation of programmed cell death GO:0043069 183 0.025
neuron differentiation GO:0030182 368 0.025
cytosolic calcium ion homeostasis GO:0051480 140 0.024
anion transport GO:0006820 178 0.024
regulation of neurogenesis GO:0050767 247 0.024
macromolecular complex assembly GO:0065003 273 0.024
regulation of cellular ketone metabolic process GO:0010565 27 0.024
regulation of cell development GO:0060284 263 0.024
regulation of multicellular organismal development GO:2000026 376 0.023
response to bacterium GO:0009617 200 0.023
organic acid metabolic process GO:0006082 292 0.023
positive regulation of hydrolase activity GO:0051345 86 0.022
reproduction GO:0000003 245 0.022
lipid metabolic process GO:0006629 283 0.022
positive regulation of cell projection organization GO:0031346 111 0.022
response to oxygen levels GO:0070482 265 0.022
cellular ketone metabolic process GO:0042180 51 0.022
immunoglobulin mediated immune response GO:0016064 4 0.022
positive regulation of neurogenesis GO:0050769 165 0.022
purine containing compound metabolic process GO:0072521 253 0.022
regulation of protein phosphorylation GO:0001932 183 0.022
positive regulation of molecular function GO:0044093 230 0.022
regulation of leukocyte differentiation GO:1902105 20 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
regulation of programmed cell death GO:0043067 341 0.021
positive regulation of protein metabolic process GO:0051247 178 0.021
positive regulation of signal transduction GO:0009967 175 0.021
protein complex assembly GO:0006461 263 0.021
positive regulation of developmental process GO:0051094 283 0.020
regulation of system process GO:0044057 208 0.020
hematopoietic or lymphoid organ development GO:0048534 36 0.020
behavior GO:0007610 205 0.020
myeloid leukocyte migration GO:0097529 20 0.020
lymphocyte mediated immunity GO:0002449 14 0.020
response to lipopolysaccharide GO:0032496 191 0.020
multi organism reproductive process GO:0044703 262 0.020
response to extracellular stimulus GO:0009991 380 0.020
cellular response to stress GO:0033554 269 0.020
regulation of cytokine production GO:0001817 56 0.020
mitotic spindle organization GO:0007052 2 0.020
positive regulation of cell development GO:0010720 176 0.020
cell migration involved in metanephros development GO:0035788 2 0.020
neuron development GO:0048666 286 0.020
positive regulation of catalytic activity GO:0043085 184 0.020
secretion by cell GO:0032940 248 0.020
sequestering of metal ion GO:0051238 9 0.019
localization of cell GO:0051674 202 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.019
glomerulus morphogenesis GO:0072102 1 0.019
multicellular organismal reproductive process GO:0048609 233 0.019
leukocyte homeostasis GO:0001776 7 0.019
regulation of platelet derived growth factor receptor signaling pathway GO:0010640 2 0.019
signal transduction by phosphorylation GO:0023014 144 0.019
cell junction maintenance GO:0034331 1 0.019
regulation of metal ion transport GO:0010959 118 0.019
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 3 0.019
negative regulation of apoptotic process GO:0043066 181 0.018
t cell activation GO:0042110 29 0.018
cellular lipid metabolic process GO:0044255 208 0.018
positive regulation of cell motility GO:2000147 97 0.018
secretion GO:0046903 307 0.018
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 5 0.018
biological adhesion GO:0022610 110 0.018
positive regulation of protein modification process GO:0031401 142 0.018
spindle organization GO:0007051 2 0.018
regulation of immune response GO:0050776 55 0.018
proline transport GO:0015824 3 0.018
response to nutrient GO:0007584 248 0.018
actin filament organization GO:0007015 42 0.018
actin filament bundle assembly GO:0051017 19 0.018
immune response regulating cell surface receptor signaling pathway GO:0002768 10 0.018
response to corticosteroid GO:0031960 235 0.017
regulation of secretion by cell GO:1903530 208 0.017
head development GO:0060322 247 0.017
regulation of actin filament based process GO:0032970 42 0.017
calcium ion transport GO:0006816 131 0.017
peptidyl amino acid modification GO:0018193 126 0.017
protein complex biogenesis GO:0070271 263 0.017
negative regulation of neurogenesis GO:0050768 78 0.017
sertoli cell proliferation GO:0060011 2 0.017
nucleobase containing small molecule metabolic process GO:0055086 316 0.017
regulation of phosphate metabolic process GO:0019220 349 0.017
cellular response to mechanical stimulus GO:0071260 48 0.017
cellular response to oxygen containing compound GO:1901701 386 0.017
regulation of calcium ion transport GO:0051924 77 0.017
regulation of b cell mediated immunity GO:0002712 2 0.017
single organism intracellular transport GO:1902582 166 0.016
regulation of macrophage chemotaxis GO:0010758 2 0.016
b cell mediated immunity GO:0019724 4 0.016
regulation of cellular protein metabolic process GO:0032268 267 0.016
positive regulation of nervous system development GO:0051962 178 0.016
regulation of immunoglobulin production GO:0002637 4 0.016
positive regulation of cellular component biogenesis GO:0044089 55 0.016
muscle structure development GO:0061061 87 0.016
regulation of homeostatic process GO:0032844 101 0.016
positive regulation of cellular biosynthetic process GO:0031328 295 0.016
response to growth factor GO:0070848 189 0.016
neuron apoptotic process GO:0051402 88 0.016
dephosphorylation GO:0016311 98 0.016
innate immune response GO:0045087 35 0.016
cell proliferation involved in heart morphogenesis GO:0061323 2 0.016
regulation of smooth muscle cell proliferation GO:0048660 75 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
positive regulation of camp mediated signaling GO:0043950 2 0.016
rna biosynthetic process GO:0032774 380 0.016
sensory perception of pain GO:0019233 73 0.016
regulation of protein modification process GO:0031399 194 0.016
regulation of catalytic activity GO:0050790 304 0.016
regulation of response to stress GO:0080134 126 0.016
response to wounding GO:0009611 254 0.016
lymphocyte activation GO:0046649 43 0.015
regulation of viral entry into host cell GO:0046596 3 0.015
mast cell chemotaxis GO:0002551 4 0.015
negative regulation of circadian sleep wake cycle non rem sleep GO:0042323 2 0.015
negative regulation of signal transduction in absence of ligand GO:1901099 3 0.015
regulation of cell morphogenesis GO:0022604 77 0.015
organic anion transport GO:0015711 132 0.015
positive regulation of protein kinase activity GO:0045860 73 0.015
cellular response to lipid GO:0071396 201 0.015
axis specification GO:0009798 4 0.015
cellular response to biotic stimulus GO:0071216 59 0.015
positive regulation of kinase activity GO:0033674 77 0.015
positive regulation of cell proliferation GO:0008284 249 0.015
response to vitamin GO:0033273 131 0.015
regulation of protein transport GO:0051223 68 0.015
immune response regulating signaling pathway GO:0002764 19 0.015
regulation of response to wounding GO:1903034 69 0.015
response to cytokine GO:0034097 215 0.014
reproductive process GO:0022414 372 0.014
positive regulation of macrophage chemotaxis GO:0010759 2 0.014
platelet aggregation GO:0070527 4 0.014
positive regulation of fc receptor mediated stimulatory signaling pathway GO:0060369 1 0.014
regulation of mapk cascade GO:0043408 116 0.014
leukocyte migration GO:0050900 38 0.014
response to nutrient levels GO:0031667 370 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.014
response to carbohydrate GO:0009743 183 0.014
inorganic cation transmembrane transport GO:0098662 202 0.013
regulation of intracellular transport GO:0032386 65 0.013
negative regulation of phosphate metabolic process GO:0045936 80 0.013
phospholipid metabolic process GO:0006644 61 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.013
response to glucocorticoid GO:0051384 223 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
regulation of heart morphogenesis GO:2000826 2 0.013
protein secretion GO:0009306 34 0.013
metanephric s shaped body morphogenesis GO:0072284 2 0.013
cytoplasmic transport GO:0016482 115 0.013
positive regulation of secretion GO:0051047 140 0.013
regulation of protein serine threonine kinase activity GO:0071900 64 0.013
immune system development GO:0002520 41 0.013
negative regulation of neuron death GO:1901215 69 0.013
inflammatory response GO:0006954 150 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
regulation of neuron death GO:1901214 115 0.013
cardiovascular system development GO:0072358 134 0.013
regulation of immunoglobulin mediated immune response GO:0002889 2 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
response to estradiol GO:0032355 164 0.012
hemopoiesis GO:0030097 34 0.012
regulation of kinase activity GO:0043549 117 0.012
transcription dna templated GO:0006351 377 0.012
regulation of neuron differentiation GO:0045664 208 0.012
regulation of myeloid cell differentiation GO:0045637 12 0.012
nitrogen compound transport GO:0071705 229 0.012
response to radiation GO:0009314 137 0.012
organic acid transport GO:0015849 116 0.012
intracellular transport GO:0046907 185 0.012
regulation of response to external stimulus GO:0032101 106 0.012
single organism reproductive process GO:0044702 297 0.012
positive regulation of immune response GO:0050778 42 0.012
regulation of anatomical structure size GO:0090066 135 0.011
action potential GO:0001508 54 0.011
activation of immune response GO:0002253 26 0.011
nucleoside phosphate metabolic process GO:0006753 283 0.011
cell adhesion mediated by integrin GO:0033627 1 0.011
negative regulation of ion transport GO:0043271 51 0.011
regulation of sensory perception GO:0051931 29 0.011
circulatory system development GO:0072359 134 0.011
single organism biosynthetic process GO:0044711 342 0.011
growth GO:0040007 165 0.011
regulation of cell motility GO:2000145 131 0.011
regulation of neurological system process GO:0031644 43 0.011
acylglycerol homeostasis GO:0055090 2 0.011
positive regulation of response to external stimulus GO:0032103 51 0.011
regulation of cellular component movement GO:0051270 150 0.011
cellular response to endogenous stimulus GO:0071495 377 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
regulation of sensory perception of pain GO:0051930 29 0.011
dorsal ventral pattern formation GO:0009953 4 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
positive regulation of g protein coupled receptor protein signaling pathway GO:0045745 4 0.011
muscle system process GO:0003012 115 0.011
cellular response to abiotic stimulus GO:0071214 85 0.011
oxoacid metabolic process GO:0043436 290 0.010
cellular macromolecule localization GO:0070727 122 0.010
multicellular organism reproduction GO:0032504 233 0.010
positive regulation of locomotion GO:0040017 102 0.010
cell cell junction organization GO:0045216 20 0.010
cell adhesion GO:0007155 110 0.010
carboxylic acid transport GO:0046942 115 0.010
monovalent inorganic cation transport GO:0015672 172 0.010
positive regulation of apoptotic process GO:0043065 154 0.010
signal release GO:0023061 145 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
protein localization to cell surface GO:0034394 1 0.010
regulation of cellular response to oxidative stress GO:1900407 7 0.010
tissue development GO:0009888 252 0.010
peptidyl tyrosine phosphorylation GO:0018108 72 0.010
lipid storage GO:0019915 1 0.010
positive regulation of interleukin 2 production GO:0032743 1 0.010

Tyrobp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org