Rattus norvegicus

17 known processes

Tyro3

TYRO3 protein tyrosine kinase

(Aliases: Brt)

Tyro3 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of phosphate metabolic process GO:0019220 349 0.074
Rat
protein phosphorylation GO:0006468 345 0.064
regulation of programmed cell death GO:0043067 341 0.062
Mouse
regulation of signal transduction GO:0009966 318 0.060
Mouse
regulation of cellular component organization GO:0051128 368 0.059
Rat
nucleotide metabolic process GO:0009117 279 0.059
cell projection organization GO:0030030 302 0.056
Rat
regulation of cellular protein metabolic process GO:0032268 267 0.054
Rat
catabolic process GO:0009056 351 0.054
transcription dna templated GO:0006351 377 0.052
Rat
multicellular organism reproduction GO:0032504 233 0.052
Mouse
neuron differentiation GO:0030182 368 0.052
Rat
rna biosynthetic process GO:0032774 380 0.052
Rat
organic substance catabolic process GO:1901575 316 0.051
positive regulation of biosynthetic process GO:0009891 319 0.050
Rat
carbohydrate derivative metabolic process GO:1901135 346 0.049
regulation of molecular function GO:0065009 398 0.048
oxoacid metabolic process GO:0043436 290 0.048
negative regulation of metabolic process GO:0009892 331 0.046
Rat
nucleic acid templated transcription GO:0097659 379 0.046
Rat
central nervous system development GO:0007417 311 0.046
Mouse Rat
rna metabolic process GO:0016070 406 0.046
Rat
carboxylic acid metabolic process GO:0019752 289 0.045
negative regulation of macromolecule metabolic process GO:0010605 260 0.044
Rat
head development GO:0060322 247 0.044
Mouse Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.043
Rat
cell cycle GO:0007049 101 0.043
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.043
Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.042
Rat
anatomical structure morphogenesis GO:0009653 298 0.041
Mouse Rat
positive regulation of cellular biosynthetic process GO:0031328 295 0.041
Rat
regulation of protein modification process GO:0031399 194 0.041
Rat
cellular component assembly GO:0022607 360 0.040
protein autophosphorylation GO:0046777 66 0.039
Human Rat
positive regulation of apoptotic process GO:0043065 154 0.039
cellular response to oxygen containing compound GO:1901701 386 0.039
Rat
protein complex biogenesis GO:0070271 263 0.039
positive regulation of gene expression GO:0010628 244 0.038
Rat
organophosphate metabolic process GO:0019637 370 0.038
cellular ketone metabolic process GO:0042180 51 0.037
regulation of catabolic process GO:0009894 113 0.037
regulation of rna metabolic process GO:0051252 391 0.037
Rat
single organism biosynthetic process GO:0044711 342 0.036
regulation of nucleic acid templated transcription GO:1903506 380 0.036
Rat
lipid metabolic process GO:0006629 283 0.036
cellular catabolic process GO:0044248 295 0.036
cellular amino acid metabolic process GO:0006520 107 0.036
regulation of apoptotic process GO:0042981 335 0.035
Mouse
positive regulation of multicellular organismal process GO:0051240 387 0.035
Rat
cation transport GO:0006812 382 0.035
intracellular signal transduction GO:0035556 314 0.035
Mouse
regulation of catalytic activity GO:0050790 304 0.034
neuron development GO:0048666 286 0.034
Rat
programmed cell death GO:0012501 392 0.034
Mouse
regulation of phosphorus metabolic process GO:0051174 349 0.034
Rat
cell cell signaling GO:0007267 335 0.034
cellular amine metabolic process GO:0044106 38 0.033
macromolecule localization GO:0033036 252 0.033
response to acid chemical GO:0001101 222 0.033
transmembrane transport GO:0055085 412 0.033
positive regulation of cell death GO:0010942 184 0.032
synaptic transmission GO:0007268 235 0.032
nucleobase containing small molecule metabolic process GO:0055086 316 0.032
regulation of multicellular organismal development GO:2000026 376 0.031
Rat
apoptotic process GO:0006915 381 0.031
Mouse
regulation of nervous system development GO:0051960 264 0.031
Rat
macromolecular complex subunit organization GO:0043933 339 0.031
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.031
Rat
negative regulation of cellular biosynthetic process GO:0031327 161 0.031
Rat
immune system process GO:0002376 204 0.031
Mouse
growth GO:0040007 165 0.030
positive regulation of catalytic activity GO:0043085 184 0.030
single organism catabolic process GO:0044712 283 0.029
protein complex assembly GO:0006461 263 0.029
purine containing compound metabolic process GO:0072521 253 0.029
negative regulation of protein metabolic process GO:0051248 114 0.028
Rat
regulation of growth GO:0040008 105 0.028
homeostatic process GO:0042592 331 0.028
Mouse Rat
regulation of anatomical structure morphogenesis GO:0022603 141 0.028
Rat
nucleoside phosphate metabolic process GO:0006753 283 0.028
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.027
Rat
regulation of protein metabolic process GO:0051246 289 0.027
Rat
amine metabolic process GO:0009308 38 0.027
purine nucleotide catabolic process GO:0006195 136 0.027
response to oxidative stress GO:0006979 186 0.027
protein complex subunit organization GO:0071822 302 0.027
behavior GO:0007610 205 0.027
ribonucleoside metabolic process GO:0009119 174 0.026
organic acid metabolic process GO:0006082 292 0.026
multi organism reproductive process GO:0044703 262 0.026
Mouse
single organism reproductive process GO:0044702 297 0.026
Mouse Rat
negative regulation of cellular metabolic process GO:0031324 281 0.026
Rat
positive regulation of programmed cell death GO:0043068 157 0.026
cell projection morphogenesis GO:0048858 123 0.026
Rat
cell cycle process GO:0022402 57 0.026
Rat
purine nucleotide metabolic process GO:0006163 229 0.025
cellular component biogenesis GO:0044085 368 0.025
small gtpase mediated signal transduction GO:0007264 36 0.025
purine nucleoside triphosphate catabolic process GO:0009146 122 0.025
positive regulation of molecular function GO:0044093 230 0.025
regulation of cellular amine metabolic process GO:0033238 8 0.025
purine containing compound catabolic process GO:0072523 138 0.025
positive regulation of signal transduction GO:0009967 175 0.024
reproductive process GO:0022414 372 0.024
Mouse Rat
ion transmembrane transport GO:0034220 365 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
carbohydrate derivative catabolic process GO:1901136 147 0.024
transcription from rna polymerase ii promoter GO:0006366 252 0.024
Rat
positive regulation of cellular component organization GO:0051130 200 0.024
Rat
multicellular organismal reproductive process GO:0048609 233 0.024
Mouse
regulation of proteasomal protein catabolic process GO:0061136 4 0.024
nucleoside metabolic process GO:0009116 179 0.024
regulation of protein phosphorylation GO:0001932 183 0.024
Rat
enzyme linked receptor protein signaling pathway GO:0007167 116 0.024
Rat
positive regulation of developmental process GO:0051094 283 0.024
Rat
cardiovascular system development GO:0072358 134 0.023
regulation of cell differentiation GO:0045595 320 0.023
Rat
regulation of neurogenesis GO:0050767 247 0.023
Rat
ribose phosphate metabolic process GO:0019693 235 0.023
positive regulation of response to stimulus GO:0048584 285 0.023
Mouse
proteolysis GO:0006508 175 0.023
secretion GO:0046903 307 0.023
Mouse Rat
tissue development GO:0009888 252 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
Rat
organelle organization GO:0006996 266 0.023
Rat
neuron projection development GO:0031175 273 0.023
Rat
protein localization GO:0008104 191 0.023
organonitrogen compound catabolic process GO:1901565 179 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.023
Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.022
nucleoside catabolic process GO:0009164 126 0.022
intracellular transport GO:0046907 185 0.022
positive regulation of signaling GO:0023056 270 0.022
locomotion GO:0040011 237 0.022
Mouse Rat
regulation of phosphorylation GO:0042325 248 0.022
Rat
ribonucleoside triphosphate metabolic process GO:0009199 141 0.022
organophosphate catabolic process GO:0046434 148 0.022
regulation of rna biosynthetic process GO:2001141 381 0.022
Rat
macromolecular complex assembly GO:0065003 273 0.021
aromatic compound catabolic process GO:0019439 168 0.021
regulation of hydrolase activity GO:0051336 143 0.021
purine ribonucleotide catabolic process GO:0009154 136 0.021
cell growth GO:0016049 104 0.021
reproduction GO:0000003 245 0.021
Mouse
ribonucleoside triphosphate catabolic process GO:0009203 122 0.021
chemical homeostasis GO:0048878 292 0.020
Rat
regulation of neuron differentiation GO:0045664 208 0.020
Rat
mesoderm development GO:0007498 2 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.020
Rat
purine ribonucleoside metabolic process GO:0046128 168 0.020
positive regulation of protein phosphorylation GO:0001934 135 0.020
Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.020
Rat
glycosyl compound metabolic process GO:1901657 182 0.020
cellular component movement GO:0006928 248 0.020
Mouse Rat
negative regulation of cell communication GO:0010648 158 0.020
Mouse
multicellular organism growth GO:0035264 1 0.020
regulation of system process GO:0044057 208 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.019
regulation of cell cycle GO:0051726 73 0.019
Rat
synaptic growth at neuromuscular junction GO:0051124 1 0.019
ribonucleoside catabolic process GO:0042454 126 0.019
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.019
Rat
positive regulation of rna biosynthetic process GO:1902680 197 0.019
Rat
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.019
negative regulation of multicellular organismal process GO:0051241 203 0.019
inorganic ion transmembrane transport GO:0098660 229 0.019
cellular response to stress GO:0033554 269 0.019
negative regulation of developmental process GO:0051093 125 0.019
regulation of cellular catabolic process GO:0031329 101 0.019
purine ribonucleotide metabolic process GO:0009150 227 0.019
cation transmembrane transport GO:0098655 263 0.018
regulation of cell proliferation GO:0042127 359 0.018
regulation of transcription dna templated GO:0006355 374 0.018
Rat
cellular nitrogen compound catabolic process GO:0044270 163 0.018
glycosyl compound catabolic process GO:1901658 126 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
positive regulation of cell communication GO:0010647 271 0.018
brain development GO:0007420 247 0.018
Mouse Rat
protein oligomerization GO:0051259 191 0.018
regulation of mapk cascade GO:0043408 116 0.018
metal ion transport GO:0030001 289 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
Rat
negative regulation of programmed cell death GO:0043069 183 0.017
Mouse
cell motility GO:0048870 202 0.017
Mouse Rat
chemosensory behavior GO:0007635 2 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
cell morphogenesis GO:0000902 142 0.017
Mouse Rat
negative regulation of molecular function GO:0044092 133 0.017
nucleoside triphosphate catabolic process GO:0009143 123 0.016
response to radiation GO:0009314 137 0.016
inorganic cation transmembrane transport GO:0098662 202 0.016
monovalent inorganic cation transport GO:0015672 172 0.016
negative regulation of biosynthetic process GO:0009890 168 0.016
Rat
vesicle mediated transport GO:0016192 181 0.016
Mouse Rat
positive regulation of transcription dna templated GO:0045893 197 0.016
Rat
forebrain development GO:0030900 98 0.016
Mouse
nucleoside phosphate catabolic process GO:1901292 140 0.016
olfactory behavior GO:0042048 2 0.016
cell part morphogenesis GO:0032990 123 0.016
Rat
response to retinoic acid GO:0032526 63 0.016
gland development GO:0048732 155 0.016
Rat
response to extracellular stimulus GO:0009991 380 0.015
cellular homeostasis GO:0019725 252 0.015
Mouse Rat
response to growth factor GO:0070848 189 0.015
Rat
negative regulation of gene expression GO:0010629 199 0.015
Rat
regulation of purine nucleotide metabolic process GO:1900542 115 0.015
action potential GO:0001508 54 0.015
axon development GO:0061564 96 0.015
axonogenesis GO:0007409 71 0.015
developmental process involved in reproduction GO:0003006 159 0.015
Mouse Rat
circulatory system development GO:0072359 134 0.015
regulation of cell growth GO:0001558 85 0.015
lipid biosynthetic process GO:0008610 128 0.015
single organism intracellular transport GO:1902582 166 0.015
organophosphate biosynthetic process GO:0090407 143 0.015
organ morphogenesis GO:0009887 75 0.015
regulation of nucleotide metabolic process GO:0006140 117 0.015
negative regulation of cellular protein metabolic process GO:0032269 106 0.015
Rat
response to inorganic substance GO:0010035 377 0.015
Rat
nucleoside triphosphate metabolic process GO:0009141 144 0.015
organic cyclic compound catabolic process GO:1901361 175 0.014
heterocycle catabolic process GO:0046700 167 0.014
regulation of cell development GO:0060284 263 0.014
Rat
regulation of intracellular signal transduction GO:1902531 218 0.014
salivary gland development GO:0007431 3 0.014
secretion by cell GO:0032940 248 0.014
Mouse
positive regulation of catabolic process GO:0009896 78 0.014
regulation of cell morphogenesis GO:0022604 77 0.014
Rat
response to oxygen levels GO:0070482 265 0.014
aging GO:0007568 241 0.014
Rat
sex differentiation GO:0007548 113 0.014
Mouse Rat
anterior posterior pattern specification GO:0009952 1 0.014
ribonucleotide metabolic process GO:0009259 231 0.014
tube development GO:0035295 89 0.014
response to toxic substance GO:0009636 133 0.014
multi multicellular organism process GO:0044706 138 0.014
establishment of protein localization GO:0045184 141 0.013
nucleoside monophosphate metabolic process GO:0009123 93 0.013
signal transduction by phosphorylation GO:0023014 144 0.013
regulation of cell projection organization GO:0031344 175 0.013
Rat
response to decreased oxygen levels GO:0036293 237 0.013
positive regulation of cell differentiation GO:0045597 217 0.013
Rat
ribonucleotide catabolic process GO:0009261 136 0.013
cellular macromolecule localization GO:0070727 122 0.013
response to hypoxia GO:0001666 231 0.013
cellular lipid metabolic process GO:0044255 208 0.013
positive regulation of protein modification process GO:0031401 142 0.013
Rat
negative regulation of cellular component organization GO:0051129 83 0.013
ras protein signal transduction GO:0007265 29 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
Rat
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.013
purine nucleoside catabolic process GO:0006152 124 0.013
regulation of synaptic transmission GO:0050804 141 0.013
organic acid transport GO:0015849 116 0.013
regulation of neuron projection development GO:0010975 161 0.013
Rat
organonitrogen compound biosynthetic process GO:1901566 167 0.013
sodium ion transport GO:0006814 82 0.013
cellular component morphogenesis GO:0032989 155 0.013
Mouse Rat
cell migration GO:0016477 197 0.013
Mouse Rat
dna metabolic process GO:0006259 96 0.013
Rat
positive regulation of rna metabolic process GO:0051254 203 0.012
Rat
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
Rat
anion transport GO:0006820 178 0.012
muscle system process GO:0003012 115 0.012
liver development GO:0001889 90 0.012
Rat
protein transport GO:0015031 132 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
cellular response to endogenous stimulus GO:0071495 377 0.012
Rat
positive regulation of phosphorylation GO:0042327 177 0.012
Rat
regulation of protein kinase activity GO:0045859 105 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
Rat
regulation of anatomical structure size GO:0090066 135 0.012
cytoplasmic transport GO:0016482 115 0.012
single organism behavior GO:0044708 130 0.012
eye morphogenesis GO:0048592 4 0.012
neuromuscular process GO:0050905 2 0.012
response to wounding GO:0009611 254 0.012
Mouse Rat
wound healing GO:0042060 122 0.012
Mouse
protein maturation GO:0051604 68 0.012
endocytosis GO:0006897 84 0.012
Mouse Rat
positive regulation of cell development GO:0010720 176 0.012
Rat
axis specification GO:0009798 4 0.012
vasculature development GO:0001944 70 0.012
regulation of transferase activity GO:0051338 123 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.011
positive regulation of cellular catabolic process GO:0031331 71 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
positive regulation of nervous system development GO:0051962 178 0.011
Rat
protein targeting GO:0006605 61 0.011
neuronal action potential GO:0019228 35 0.011
negative regulation of cell death GO:0060548 229 0.011
Mouse
gonad development GO:0008406 104 0.011
Rat
localization of cell GO:0051674 202 0.011
Mouse Rat
regulation of homeostatic process GO:0032844 101 0.011
response to nutrient GO:0007584 248 0.011
epithelium development GO:0060429 96 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
peptidyl amino acid modification GO:0018193 126 0.011
Human Rat
response to hydrogen peroxide GO:0042542 89 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
Rat
cell morphogenesis involved in differentiation GO:0000904 119 0.011
Mouse Rat
response to nutrient levels GO:0031667 370 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
dephosphorylation GO:0016311 98 0.011
adult locomotory behavior GO:0008344 4 0.011
developmental growth GO:0048589 100 0.011
response to biotic stimulus GO:0009607 226 0.011
protein heterooligomerization GO:0051291 89 0.011
blood vessel morphogenesis GO:0048514 58 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.010
regulation of cellular localization GO:0060341 263 0.010
positive regulation of mapk cascade GO:0043410 92 0.010
cell adhesion GO:0007155 110 0.010
Mouse
chemotaxis GO:0006935 66 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
establishment of organelle localization GO:0051656 37 0.010
angiogenesis GO:0001525 53 0.010
single organism organelle organization GO:1902589 180 0.010
Rat
reactive oxygen species metabolic process GO:0072593 37 0.010
purine ribonucleoside catabolic process GO:0046130 124 0.010
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.010
Rat
regulation of purine nucleotide catabolic process GO:0033121 65 0.010
gliogenesis GO:0042063 93 0.010
Rat
reproductive system development GO:0061458 128 0.010
Mouse Rat
salivary gland morphogenesis GO:0007435 1 0.010
nucleobase containing compound catabolic process GO:0034655 152 0.010
negative regulation of cell differentiation GO:0045596 99 0.010
regulation of kinase activity GO:0043549 117 0.010

Tyro3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015