Rattus norvegicus

26 known processes

Rln1

relaxin 1

(Aliases: RELAX)

Rln1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell proliferation GO:0042127 359 0.223
response to extracellular stimulus GO:0009991 380 0.161
cellular response to peptide GO:1901653 133 0.156
response to glucocorticoid GO:0051384 223 0.148
response to corticosteroid GO:0031960 235 0.147
gland development GO:0048732 155 0.146
Mouse
response to peptide hormone GO:0043434 278 0.137
protein phosphorylation GO:0006468 345 0.125
response to nutrient levels GO:0031667 370 0.122
cellular response to oxygen containing compound GO:1901701 386 0.117
response to oxygen levels GO:0070482 265 0.115
cation transport GO:0006812 382 0.115
homeostatic process GO:0042592 331 0.112
regulation of cellular component organization GO:0051128 368 0.107
single organism reproductive process GO:0044702 297 0.102
Mouse
response to ketone GO:1901654 182 0.094
response to insulin GO:0032868 133 0.090
response to inorganic substance GO:0010035 377 0.088
regulation of phosphorus metabolic process GO:0051174 349 0.087
response to other organism GO:0051707 220 0.083
response to glucose GO:0009749 136 0.078
response to carbohydrate GO:0009743 183 0.076
cellular response to gonadotropin stimulus GO:0071371 17 0.076
response to peptide GO:1901652 292 0.075
response to estrogen GO:0043627 232 0.072
central nervous system development GO:0007417 311 0.072
kidney development GO:0001822 67 0.071
nucleobase containing small molecule metabolic process GO:0055086 316 0.070
regulation of cellular protein metabolic process GO:0032268 267 0.069
leydig cell differentiation GO:0033327 8 0.069
cellular response to peptide hormone stimulus GO:0071375 120 0.068
response to acid chemical GO:0001101 222 0.068
response to transition metal nanoparticle GO:1990267 122 0.067
regulation of transferase activity GO:0051338 123 0.066
cellular amino acid metabolic process GO:0006520 107 0.063
steroid biosynthetic process GO:0006694 48 0.061
vascular process in circulatory system GO:0003018 96 0.061
response to vitamin GO:0033273 131 0.060
positive regulation of cellular amine metabolic process GO:0033240 3 0.058
regulation of rna metabolic process GO:0051252 391 0.058
transmembrane transport GO:0055085 412 0.058
hormone transport GO:0009914 121 0.058
response to decreased oxygen levels GO:0036293 237 0.057
positive regulation of phosphate metabolic process GO:0045937 262 0.057
renal system development GO:0072001 67 0.057
cellular response to stress GO:0033554 269 0.056
regulation of hormone levels GO:0010817 187 0.055
rhythmic process GO:0048511 156 0.054
response to hexose GO:0009746 144 0.054
male gonad development GO:0008584 59 0.052
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.052
multicellular organismal reproductive process GO:0048609 233 0.052
regulation of blood vessel size GO:0050880 89 0.050
regulation of protein modification process GO:0031399 194 0.050
anion transport GO:0006820 178 0.050
response to hypoxia GO:0001666 231 0.050
positive regulation of phosphorus metabolic process GO:0010562 262 0.050
secretion GO:0046903 307 0.049
regulation of protein metabolic process GO:0051246 289 0.049
regulation of peptide secretion GO:0002791 82 0.048
circulatory system process GO:0003013 183 0.048
response to nutrient GO:0007584 248 0.046
programmed cell death GO:0012501 392 0.046
regulation of ion transport GO:0043269 245 0.046
regulation of multicellular organismal development GO:2000026 376 0.046
male sex differentiation GO:0046661 64 0.046
regulation of system process GO:0044057 208 0.046
response to monosaccharide GO:0034284 159 0.045
cellular response to hormone stimulus GO:0032870 247 0.045
positive regulation of multicellular organismal process GO:0051240 387 0.045
positive regulation of transferase activity GO:0051347 81 0.045
cellular response to external stimulus GO:0071496 118 0.044
carbohydrate derivative metabolic process GO:1901135 346 0.044
positive regulation of phosphorylation GO:0042327 177 0.043
rna metabolic process GO:0016070 406 0.043
regulation of molecular function GO:0065009 398 0.043
regulation of cellular localization GO:0060341 263 0.043
regulation of cell differentiation GO:0045595 320 0.043
apoptotic process GO:0006915 381 0.043
response to wounding GO:0009611 254 0.042
cellular response to follicle stimulating hormone stimulus GO:0071372 13 0.042
regulation of phosphorylation GO:0042325 248 0.041
macromolecular complex assembly GO:0065003 273 0.041
regulation of tube size GO:0035150 89 0.041
regulation of anatomical structure size GO:0090066 135 0.040
regulation of cellular amine metabolic process GO:0033238 8 0.039
cellular response to alcohol GO:0097306 87 0.039
positive regulation of metanephros development GO:0072216 2 0.038
positive regulation of protein kinase activity GO:0045860 73 0.038
regulation of phosphate metabolic process GO:0019220 349 0.038
cellular response to nitrogen compound GO:1901699 210 0.038
chemical homeostasis GO:0048878 292 0.038
negative regulation of cellular metabolic process GO:0031324 281 0.037
cellular response to lipid GO:0071396 201 0.037
negative regulation of apoptotic process GO:0043066 181 0.037
amine metabolic process GO:0009308 38 0.036
cellular response to organonitrogen compound GO:0071417 197 0.036
cellular component assembly GO:0022607 360 0.035
brain development GO:0007420 247 0.035
reproductive structure development GO:0048608 128 0.035
Mouse
reproductive process GO:0022414 372 0.035
Mouse
positive regulation of signal transduction GO:0009967 175 0.035
cellular response to endogenous stimulus GO:0071495 377 0.035
multi organism reproductive process GO:0044703 262 0.034
positive regulation of biosynthetic process GO:0009891 319 0.034
response to growth factor GO:0070848 189 0.034
response to metal ion GO:0010038 253 0.034
cellular response to organic cyclic compound GO:0071407 202 0.033
response to ethanol GO:0045471 162 0.032
cellular homeostasis GO:0019725 252 0.032
protein oligomerization GO:0051259 191 0.032
regulation of nervous system development GO:0051960 264 0.032
single organism biosynthetic process GO:0044711 342 0.032
organ regeneration GO:0031100 101 0.031
urogenital system development GO:0001655 78 0.031
Mouse
cation homeostasis GO:0055080 195 0.030
positive regulation of signaling GO:0023056 270 0.030
negative regulation of macromolecule metabolic process GO:0010605 260 0.030
protein heterooligomerization GO:0051291 89 0.030
regulation of protein kinase activity GO:0045859 105 0.030
tube development GO:0035295 89 0.030
synaptic transmission GO:0007268 235 0.030
protein complex assembly GO:0006461 263 0.029
regulation of protein phosphorylation GO:0001932 183 0.029
positive regulation of developmental process GO:0051094 283 0.029
cellular amine metabolic process GO:0044106 38 0.029
positive regulation of protein phosphorylation GO:0001934 135 0.029
negative regulation of metabolic process GO:0009892 331 0.029
lipid metabolic process GO:0006629 283 0.029
regulation of cellular amino acid metabolic process GO:0006521 2 0.029
regulation of transcription dna templated GO:0006355 374 0.029
positive regulation of molecular function GO:0044093 230 0.028
neuron differentiation GO:0030182 368 0.028
response to gonadotropin GO:0034698 34 0.028
insulin like growth factor receptor signaling pathway GO:0048009 3 0.028
regulation of kinase activity GO:0043549 117 0.028
regulation of apoptotic process GO:0042981 335 0.027
sensory perception GO:0007600 101 0.027
steroid metabolic process GO:0008202 73 0.027
protein complex biogenesis GO:0070271 263 0.027
multicellular organism reproduction GO:0032504 233 0.026
tissue development GO:0009888 252 0.026
amide transport GO:0042886 105 0.026
regulation of cellular ketone metabolic process GO:0010565 27 0.026
reproduction GO:0000003 245 0.026
positive regulation of secretion GO:0051047 140 0.026
negative regulation of cell death GO:0060548 229 0.025
regulation of rna biosynthetic process GO:2001141 381 0.024
positive regulation of catalytic activity GO:0043085 184 0.024
regulation of programmed cell death GO:0043067 341 0.024
positive regulation of cell differentiation GO:0045597 217 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
progesterone biosynthetic process GO:0006701 3 0.023
cellular response to oxygen levels GO:0071453 60 0.023
negative regulation of programmed cell death GO:0043069 183 0.023
head development GO:0060322 247 0.023
signal transduction by phosphorylation GO:0023014 144 0.023
inflammatory response GO:0006954 150 0.023
locomotion GO:0040011 237 0.022
epithelium development GO:0060429 96 0.022
developmental process involved in reproduction GO:0003006 159 0.022
Mouse
peptidyl tyrosine modification GO:0018212 72 0.022
lipid transport GO:0006869 61 0.022
hormone metabolic process GO:0042445 69 0.022
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.021
rhythmic behavior GO:0007622 24 0.021
gonad development GO:0008406 104 0.021
response to external biotic stimulus GO:0043207 221 0.021
regulation of blood circulation GO:1903522 110 0.021
cell cell signaling GO:0007267 335 0.021
regulation of cellular component biogenesis GO:0044087 86 0.021
cellular ketone metabolic process GO:0042180 51 0.021
cellular hormone metabolic process GO:0034754 49 0.021
cell projection organization GO:0030030 302 0.020
development of primary sexual characteristics GO:0045137 107 0.020
response to bacterium GO:0009617 200 0.020
cellular response to growth factor stimulus GO:0071363 162 0.020
cellular component movement GO:0006928 248 0.020
renal system process GO:0003014 40 0.020
sexual reproduction GO:0019953 148 0.020
positive regulation of cell communication GO:0010647 271 0.020
macromolecular complex subunit organization GO:0043933 339 0.020
regeneration GO:0031099 163 0.020
response to molecule of bacterial origin GO:0002237 194 0.020
carboxylic acid biosynthetic process GO:0046394 83 0.020
positive regulation of protein modification process GO:0031401 142 0.020
positive regulation of cellular component organization GO:0051130 200 0.020
response to ph GO:0009268 27 0.020
development of primary male sexual characteristics GO:0046546 59 0.020
positive regulation of response to stimulus GO:0048584 285 0.020
g protein coupled receptor signaling pathway GO:0007186 242 0.019
response to hydrogen peroxide GO:0042542 89 0.019
gamete generation GO:0007276 124 0.019
regulation of body fluid levels GO:0050878 90 0.019
dicarboxylic acid metabolic process GO:0043648 42 0.019
organophosphate metabolic process GO:0019637 370 0.019
cellular calcium ion homeostasis GO:0006874 160 0.019
cellular component biogenesis GO:0044085 368 0.019
cellular response to insulin stimulus GO:0032869 81 0.019
regulation of catalytic activity GO:0050790 304 0.019
enzyme linked receptor protein signaling pathway GO:0007167 116 0.019
regulation of metanephros development GO:0072215 4 0.019
nucleotide metabolic process GO:0009117 279 0.019
glucose homeostasis GO:0042593 75 0.019
ribose phosphate metabolic process GO:0019693 235 0.018
response to antibiotic GO:0046677 39 0.018
cell cycle GO:0007049 101 0.018
lipid biosynthetic process GO:0008610 128 0.018
positive regulation of cellular biosynthetic process GO:0031328 295 0.018
response to hyperoxia GO:0055093 45 0.018
regulation of peptide hormone secretion GO:0090276 80 0.018
transcription dna templated GO:0006351 377 0.018
intracellular signal transduction GO:0035556 314 0.018
nucleic acid templated transcription GO:0097659 379 0.017
wound healing GO:0042060 122 0.017
response to calcium ion GO:0051592 59 0.017
g1 s transition of mitotic cell cycle GO:0000082 12 0.017
cellular response to acid chemical GO:0071229 75 0.017
protein complex subunit organization GO:0071822 302 0.017
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
response to biotic stimulus GO:0009607 226 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
carbohydrate homeostasis GO:0033500 75 0.016
somatostatin receptor signaling pathway GO:0038169 4 0.016
regulation of mapk cascade GO:0043408 116 0.016
cellular ion homeostasis GO:0006873 184 0.016
vasoconstriction GO:0042310 54 0.016
cellular chemical homeostasis GO:0055082 247 0.016
cellular response to hexose stimulus GO:0071331 65 0.016
anion transmembrane transport GO:0098656 77 0.016
response to follicle stimulating hormone GO:0032354 18 0.016
negative regulation of cellular protein metabolic process GO:0032269 106 0.016
response to histamine GO:0034776 3 0.016
regulation of protein serine threonine kinase activity GO:0071900 64 0.016
adrenal gland development GO:0030325 11 0.015
actin filament based process GO:0030029 86 0.015
positive regulation of secretion by cell GO:1903532 128 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.015
response to lipopolysaccharide GO:0032496 191 0.015
acute inflammatory response GO:0002526 58 0.015
epithelial cell differentiation GO:0030855 71 0.015
nitrogen compound transport GO:0071705 229 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.014
behavioral response to ethanol GO:0048149 1 0.014
response to estradiol GO:0032355 164 0.014
glial cell differentiation GO:0010001 65 0.014
negative regulation of protein metabolic process GO:0051248 114 0.014
monovalent inorganic cation transport GO:0015672 172 0.014
regulation of cell development GO:0060284 263 0.014
neuron development GO:0048666 286 0.014
regulation of transporter activity GO:0032409 50 0.014
intracellular transport GO:0046907 185 0.014
cellular cation homeostasis GO:0030003 180 0.014
cell cycle g1 s phase transition GO:0044843 13 0.014
response to dexamethasone GO:0071548 49 0.014
regulation of locomotion GO:0040012 148 0.014
response to vitamin e GO:0033197 24 0.014
positive regulation of nervous system development GO:0051962 178 0.014
fractalkine metabolic process GO:0050756 3 0.014
cellular lipid metabolic process GO:0044255 208 0.013
regulation of blood pressure GO:0008217 83 0.013
multi multicellular organism process GO:0044706 138 0.013
regulation of signal transduction GO:0009966 318 0.013
response to food GO:0032094 27 0.013
forebrain development GO:0030900 98 0.013
cellular response to steroid hormone stimulus GO:0071383 93 0.013
vasodilation GO:0042311 44 0.013
positive regulation of homeostatic process GO:0032846 49 0.013
anatomical structure morphogenesis GO:0009653 298 0.013
hormone biosynthetic process GO:0042446 25 0.013
signal release GO:0023061 145 0.013
positive regulation of cellular component biogenesis GO:0044089 55 0.013
divalent metal ion transport GO:0070838 132 0.013
somatostatin signaling pathway GO:0038170 4 0.013
defense response GO:0006952 194 0.013
response to activity GO:0014823 73 0.013
cell cycle process GO:0022402 57 0.013
organic hydroxy compound metabolic process GO:1901615 115 0.012
cellular response to hypoxia GO:0071456 51 0.012
cellular response to monosaccharide stimulus GO:0071326 67 0.012
circadian rhythm GO:0007623 88 0.012
regulation of membrane potential GO:0042391 110 0.012
growth GO:0040007 165 0.012
Mouse
regulation of intracellular signal transduction GO:1902531 218 0.012
negative regulation of molecular function GO:0044092 133 0.012
regulation of metal ion transport GO:0010959 118 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
response to cytokine GO:0034097 215 0.012
actin cytoskeleton organization GO:0030036 73 0.012
oxoacid metabolic process GO:0043436 290 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
spermatogenesis GO:0007283 99 0.012
positive regulation of blood circulation GO:1903524 65 0.011
nucleoside metabolic process GO:0009116 179 0.011
cellular response to glucose stimulus GO:0071333 65 0.011
positive regulation of cell development GO:0010720 176 0.011
organic acid metabolic process GO:0006082 292 0.011
response to testosterone GO:0033574 55 0.011
regulation of response to food GO:0032095 11 0.011
sensory organ development GO:0007423 74 0.011
divalent inorganic cation transport GO:0072511 134 0.011
regulation of cell projection organization GO:0031344 175 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
cellular response to ketone GO:1901655 51 0.011
neuron projection development GO:0031175 273 0.011
ovulation cycle GO:0042698 67 0.011
regulation of stem cell differentiation GO:2000736 2 0.011
regulation of heart contraction GO:0008016 48 0.011
regulation of smooth muscle cell migration GO:0014910 36 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
progesterone metabolic process GO:0042448 8 0.011
organic substance catabolic process GO:1901575 316 0.011
body fluid secretion GO:0007589 41 0.011
regulation of epithelial cell proliferation GO:0050678 49 0.011
response to oxidative stress GO:0006979 186 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
organonitrogen compound catabolic process GO:1901565 179 0.010
negative regulation of multicellular organismal process GO:0051241 203 0.010
regulation of homeostatic process GO:0032844 101 0.010
catabolic process GO:0009056 351 0.010
cardiovascular system development GO:0072358 134 0.010
negative regulation of transcription dna templated GO:0045892 116 0.010
chemokine metabolic process GO:0050755 3 0.010
response to purine containing compound GO:0014074 126 0.010
regulation of ion homeostasis GO:2000021 63 0.010
cellular response to dexamethasone stimulus GO:0071549 36 0.010
saliva secretion GO:0046541 3 0.010
response to camp GO:0051591 91 0.010
positive regulation of kinase activity GO:0033674 77 0.010
organic cyclic compound catabolic process GO:1901361 175 0.010
glomerular mesangial cell proliferation GO:0072110 4 0.010
response to starvation GO:0042594 59 0.010
axon ensheathment GO:0008366 40 0.010
negative regulation of nucleic acid templated transcription GO:1903507 117 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
female pregnancy GO:0007565 122 0.010
maternal process involved in female pregnancy GO:0060135 38 0.010

Rln1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
congenital adrenal hyperplasia DOID:0050811 0 0.047
disease of metabolism DOID:0014667 0 0.047
lipid metabolism disorder DOID:3146 0 0.047
inherited metabolic disorder DOID:655 0 0.047
steroid inherited metabolic disorder DOID:1701 0 0.047
disease of anatomical entity DOID:7 0 0.022
urinary system disease DOID:18 0 0.022
endocrine system disease DOID:28 0 0.016
kidney disease DOID:557 0 0.014