Rattus norvegicus

66 known processes

Polg

polymerase (DNA directed), gamma

Polg biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism catabolic process GO:0044712 283 0.079
aromatic compound catabolic process GO:0019439 168 0.066
regulation of protein metabolic process GO:0051246 289 0.061
oxoacid metabolic process GO:0043436 290 0.061
organic acid metabolic process GO:0006082 292 0.060
cellular catabolic process GO:0044248 295 0.055
catabolic process GO:0009056 351 0.055
nucleobase containing small molecule metabolic process GO:0055086 316 0.055
cellular component assembly GO:0022607 360 0.054
organic substance catabolic process GO:1901575 316 0.053
nucleoside metabolic process GO:0009116 179 0.052
protein complex assembly GO:0006461 263 0.052
carboxylic acid metabolic process GO:0019752 289 0.049
regulation of molecular function GO:0065009 398 0.048
ribonucleotide metabolic process GO:0009259 231 0.046
protein complex biogenesis GO:0070271 263 0.046
macromolecular complex subunit organization GO:0043933 339 0.046
glycosyl compound metabolic process GO:1901657 182 0.045
ribonucleoside metabolic process GO:0009119 174 0.045
purine ribonucleoside metabolic process GO:0046128 168 0.044
regulation of cellular catabolic process GO:0031329 101 0.043
cellular amino acid metabolic process GO:0006520 107 0.042
nucleotide metabolic process GO:0009117 279 0.042
nucleic acid templated transcription GO:0097659 379 0.042
regulation of transcription dna templated GO:0006355 374 0.041
macromolecular complex assembly GO:0065003 273 0.041
purine ribonucleoside catabolic process GO:0046130 124 0.039
ribonucleoside catabolic process GO:0042454 126 0.039
regulation of rna biosynthetic process GO:2001141 381 0.038
nucleoside phosphate metabolic process GO:0006753 283 0.038
ribonucleoside triphosphate metabolic process GO:0009199 141 0.038
regulation of catabolic process GO:0009894 113 0.037
purine containing compound catabolic process GO:0072523 138 0.037
purine nucleoside triphosphate catabolic process GO:0009146 122 0.037
regulation of cellular component organization GO:0051128 368 0.036
organophosphate metabolic process GO:0019637 370 0.036
regulation of phosphorus metabolic process GO:0051174 349 0.035
response to oxidative stress GO:0006979 186 0.035
sulfur compound metabolic process GO:0006790 70 0.035
positive regulation of phosphate metabolic process GO:0045937 262 0.035
positive regulation of cellular component organization GO:0051130 200 0.034
macromolecule localization GO:0033036 252 0.034
purine ribonucleotide metabolic process GO:0009150 227 0.034
ribose phosphate metabolic process GO:0019693 235 0.034
regulation of signal transduction GO:0009966 318 0.034
purine nucleotide metabolic process GO:0006163 229 0.033
organonitrogen compound catabolic process GO:1901565 179 0.033
purine nucleoside metabolic process GO:0042278 169 0.033
rna metabolic process GO:0016070 406 0.033
glycosyl compound catabolic process GO:1901658 126 0.033
carbohydrate derivative metabolic process GO:1901135 346 0.032
cellular response to stress GO:0033554 269 0.032
purine containing compound metabolic process GO:0072521 253 0.032
heterocycle catabolic process GO:0046700 167 0.032
cellular amine metabolic process GO:0044106 38 0.032
transcription dna templated GO:0006351 377 0.032
regulation of rna metabolic process GO:0051252 391 0.031
protein phosphorylation GO:0006468 345 0.031
cellular nitrogen compound catabolic process GO:0044270 163 0.031
regulation of intracellular signal transduction GO:1902531 218 0.031
purine ribonucleotide catabolic process GO:0009154 136 0.031
protein complex subunit organization GO:0071822 302 0.031
ras protein signal transduction GO:0007265 29 0.030
regulation of catalytic activity GO:0050790 304 0.030
response to decreased oxygen levels GO:0036293 237 0.030
positive regulation of cell differentiation GO:0045597 217 0.030
regulation of programmed cell death GO:0043067 341 0.030
regulation of apoptotic process GO:0042981 335 0.030
cellular ketone metabolic process GO:0042180 51 0.030
transcription from rna polymerase ii promoter GO:0006366 252 0.029
nucleoside catabolic process GO:0009164 126 0.029
rna biosynthetic process GO:0032774 380 0.029
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.029
response to hypoxia GO:0001666 231 0.029
small gtpase mediated signal transduction GO:0007264 36 0.029
purine nucleoside triphosphate metabolic process GO:0009144 141 0.028
programmed cell death GO:0012501 392 0.028
nucleoside triphosphate metabolic process GO:0009141 144 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.027
regulation of cell differentiation GO:0045595 320 0.027
cation transport GO:0006812 382 0.027
regulation of cellular ketone metabolic process GO:0010565 27 0.027
carbohydrate derivative catabolic process GO:1901136 147 0.027
regulation of cellular protein metabolic process GO:0032268 267 0.027
purine nucleoside catabolic process GO:0006152 124 0.026
ribonucleoside triphosphate catabolic process GO:0009203 122 0.026
regulation of protein modification process GO:0031399 194 0.026
single organism biosynthetic process GO:0044711 342 0.026
guanosine containing compound metabolic process GO:1901068 74 0.026
positive regulation of neurogenesis GO:0050769 165 0.026
purine nucleotide catabolic process GO:0006195 136 0.025
positive regulation of biosynthetic process GO:0009891 319 0.025
protein oligomerization GO:0051259 191 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.024
nucleobase containing compound catabolic process GO:0034655 152 0.024
cellular response to oxygen containing compound GO:1901701 386 0.024
cellular component morphogenesis GO:0032989 155 0.024
regulation of protein phosphorylation GO:0001932 183 0.024
organophosphate catabolic process GO:0046434 148 0.024
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.024
regulation of cell development GO:0060284 263 0.024
regulation of phosphate metabolic process GO:0019220 349 0.024
regulation of nucleotide catabolic process GO:0030811 65 0.023
regulation of cellular amine metabolic process GO:0033238 8 0.023
negative regulation of cellular metabolic process GO:0031324 281 0.023
nucleoside triphosphate catabolic process GO:0009143 123 0.023
reproductive process GO:0022414 372 0.023
apoptotic process GO:0006915 381 0.022
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
regulation of nucleotide metabolic process GO:0006140 117 0.022
regulation of phosphorylation GO:0042325 248 0.022
central nervous system development GO:0007417 311 0.022
regulation of nucleic acid templated transcription GO:1903506 380 0.022
positive regulation of response to stimulus GO:0048584 285 0.022
organelle organization GO:0006996 266 0.021
intracellular signal transduction GO:0035556 314 0.021
positive regulation of molecular function GO:0044093 230 0.021
positive regulation of nucleic acid templated transcription GO:1903508 197 0.021
anatomical structure morphogenesis GO:0009653 298 0.021
ribonucleotide catabolic process GO:0009261 136 0.021
peptidyl amino acid modification GO:0018193 126 0.021
organic cyclic compound catabolic process GO:1901361 175 0.021
nucleotide catabolic process GO:0009166 139 0.021
positive regulation of catalytic activity GO:0043085 184 0.021
nucleoside phosphate catabolic process GO:1901292 140 0.020
response to nutrient levels GO:0031667 370 0.020
response to oxygen levels GO:0070482 265 0.020
cell projection organization GO:0030030 302 0.020
guanosine containing compound catabolic process GO:1901069 71 0.020
cellular modified amino acid metabolic process GO:0006575 61 0.020
regulation of purine nucleotide metabolic process GO:1900542 115 0.020
amine metabolic process GO:0009308 38 0.020
negative regulation of macromolecule metabolic process GO:0010605 260 0.020
positive regulation of cellular catabolic process GO:0031331 71 0.020
positive regulation of signal transduction GO:0009967 175 0.019
positive regulation of protein metabolic process GO:0051247 178 0.019
reproduction GO:0000003 245 0.019
cellular component biogenesis GO:0044085 368 0.019
positive regulation of multicellular organismal process GO:0051240 387 0.018
positive regulation of nervous system development GO:0051962 178 0.018
positive regulation of cellular protein metabolic process GO:0032270 167 0.018
cellular response to endogenous stimulus GO:0071495 377 0.018
regulation of neurogenesis GO:0050767 247 0.018
multi organism reproductive process GO:0044703 262 0.018
regulation of cellular amino acid metabolic process GO:0006521 2 0.018
cellular component movement GO:0006928 248 0.018
response to extracellular stimulus GO:0009991 380 0.018
regulation of nervous system development GO:0051960 264 0.017
positive regulation of developmental process GO:0051094 283 0.017
positive regulation of neuron differentiation GO:0045666 126 0.017
regulation of multicellular organismal development GO:2000026 376 0.017
positive regulation of gene expression GO:0010628 244 0.017
positive regulation of cell development GO:0010720 176 0.017
alpha amino acid metabolic process GO:1901605 71 0.017
positive regulation of catabolic process GO:0009896 78 0.017
negative regulation of metabolic process GO:0009892 331 0.017
positive regulation of phosphorylation GO:0042327 177 0.016
regulation of purine nucleotide catabolic process GO:0033121 65 0.016
neuron projection development GO:0031175 273 0.016
transmembrane transport GO:0055085 412 0.016
positive regulation of protein phosphorylation GO:0001934 135 0.016
positive regulation of protein modification process GO:0031401 142 0.016
coenzyme metabolic process GO:0006732 86 0.016
response to growth factor GO:0070848 189 0.016
regulation of neuron differentiation GO:0045664 208 0.016
neuron differentiation GO:0030182 368 0.015
neuron development GO:0048666 286 0.015
regulation of cellular localization GO:0060341 263 0.015
regulation of hydrolase activity GO:0051336 143 0.015
regulation of gtpase activity GO:0043087 57 0.015
lipid storage GO:0019915 1 0.015
regulation of nucleoside metabolic process GO:0009118 66 0.015
cellular homeostasis GO:0019725 252 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.015
positive regulation of neuron projection development GO:0010976 99 0.015
regulation of cell cycle GO:0051726 73 0.014
protein localization GO:0008104 191 0.014
response to inorganic substance GO:0010035 377 0.014
secretion GO:0046903 307 0.014
gtp metabolic process GO:0046039 72 0.014
proteolysis GO:0006508 175 0.014
head development GO:0060322 247 0.014
multicellular organismal reproductive process GO:0048609 233 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.014
positive regulation of nucleoside metabolic process GO:0045979 55 0.014
cellular lipid metabolic process GO:0044255 208 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
lipid metabolic process GO:0006629 283 0.014
negative regulation of signal transduction GO:0009968 83 0.013
ribonucleoside monophosphate metabolic process GO:0009161 88 0.013
cellular protein localization GO:0034613 122 0.013
response to peptide hormone GO:0043434 278 0.013
negative regulation of cell death GO:0060548 229 0.013
single organism organelle organization GO:1902589 180 0.013
asymmetric protein localization GO:0008105 2 0.013
single organism intracellular transport GO:1902582 166 0.013
multicellular organism growth GO:0035264 1 0.013
regulation of kinase activity GO:0043549 117 0.013
regulation of ras gtpase activity GO:0032318 32 0.013
regulation of transferase activity GO:0051338 123 0.013
negative regulation of gene expression GO:0010629 199 0.013
brain development GO:0007420 247 0.013
regulation of response to stress GO:0080134 126 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
gtp catabolic process GO:0006184 71 0.013
homeostatic process GO:0042592 331 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
regulation of gtp catabolic process GO:0033124 58 0.012
regulation of neuron projection development GO:0010975 161 0.012
chemical homeostasis GO:0048878 292 0.012
vesicle mediated transport GO:0016192 181 0.012
protein transport GO:0015031 132 0.012
oxidation reduction process GO:0055114 304 0.012
negative regulation of cell communication GO:0010648 158 0.012
regulation of protein kinase activity GO:0045859 105 0.012
intracellular transport GO:0046907 185 0.012
establishment of protein localization GO:0045184 141 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
cofactor metabolic process GO:0051186 95 0.012
regulation of mesenchymal cell proliferation GO:0010464 4 0.012
response to wounding GO:0009611 254 0.012
positive regulation of cell projection organization GO:0031346 111 0.012
response to ketone GO:1901654 182 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
cell part morphogenesis GO:0032990 123 0.012
positive regulation of transport GO:0051050 245 0.012
negative regulation of transport GO:0051051 136 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.012
b cell differentiation GO:0030183 2 0.012
chromosome segregation GO:0007059 2 0.012
rho protein signal transduction GO:0007266 11 0.012
regulation of proteasomal protein catabolic process GO:0061136 4 0.012
positive regulation of cellular biosynthetic process GO:0031328 295 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.011
cellular response to peptide GO:1901653 133 0.011
neural crest cell migration GO:0001755 1 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
response to peptide GO:1901652 292 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
regulation of cell projection organization GO:0031344 175 0.011
nitrogen compound transport GO:0071705 229 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
monocarboxylic acid metabolic process GO:0032787 152 0.011
rhythmic process GO:0048511 156 0.011
negative regulation of developmental process GO:0051093 125 0.011
regulation of membrane potential GO:0042391 110 0.011
regulation of ras protein signal transduction GO:0046578 45 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.011
negative regulation of transcription dna templated GO:0045892 116 0.011
defense response to gram negative bacterium GO:0050829 3 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
defense response GO:0006952 194 0.011
regulation of protein localization GO:0032880 81 0.010
gastrulation GO:0007369 2 0.010
regulation of fat cell differentiation GO:0045598 3 0.010
single organism cellular localization GO:1902580 102 0.010
cardiovascular system development GO:0072358 134 0.010
response to nutrient GO:0007584 248 0.010
cytoplasmic transport GO:0016482 115 0.010
cell cycle GO:0007049 101 0.010
epithelium development GO:0060429 96 0.010
positive regulation of hydrolase activity GO:0051345 86 0.010
nucleoside monophosphate metabolic process GO:0009123 93 0.010
cellular response to organonitrogen compound GO:0071417 197 0.010
cellular response to oxidative stress GO:0034599 76 0.010
axis specification GO:0009798 4 0.010
multicellular organism reproduction GO:0032504 233 0.010

Polg disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
sensory system disease DOID:0050155 0 0.020
eye and adnexa disease DOID:1492 0 0.015
eye disease DOID:5614 0 0.015
musculoskeletal system disease DOID:17 0 0.010