Rattus norvegicus

0 known processes

Polk

polymerase (DNA directed) kappa

(Aliases: Dinb1)

Polk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular component organization GO:0051128 368 0.080
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.067
regulation of neurogenesis GO:0050767 247 0.061
programmed cell death GO:0012501 392 0.058
regulation of multicellular organismal development GO:2000026 376 0.055
regulation of neuron differentiation GO:0045664 208 0.054
positive regulation of neurogenesis GO:0050769 165 0.053
organelle organization GO:0006996 266 0.052
negative regulation of metabolic process GO:0009892 331 0.050
positive regulation of gene expression GO:0010628 244 0.049
oxoacid metabolic process GO:0043436 290 0.048
protein complex assembly GO:0006461 263 0.048
nucleic acid templated transcription GO:0097659 379 0.047
response to radiation GO:0009314 137 0.045
organic substance catabolic process GO:1901575 316 0.045
cellular amino acid metabolic process GO:0006520 107 0.044
macromolecular complex subunit organization GO:0043933 339 0.044
positive regulation of cellular biosynthetic process GO:0031328 295 0.043
regulation of nervous system development GO:0051960 264 0.042
rna biosynthetic process GO:0032774 380 0.042
regulation of programmed cell death GO:0043067 341 0.041
negative regulation of cellular metabolic process GO:0031324 281 0.041
regulation of cell differentiation GO:0045595 320 0.040
positive regulation of multicellular organismal process GO:0051240 387 0.039
regulation of phosphate metabolic process GO:0019220 349 0.039
regulation of cell development GO:0060284 263 0.039
catabolic process GO:0009056 351 0.038
regulation of cellular amino acid metabolic process GO:0006521 2 0.037
intracellular signal transduction GO:0035556 314 0.036
regulation of cell proliferation GO:0042127 359 0.036
negative regulation of macromolecule metabolic process GO:0010605 260 0.036
carbohydrate derivative metabolic process GO:1901135 346 0.035
cellular homeostasis GO:0019725 252 0.035
neuron differentiation GO:0030182 368 0.035
regulation of cell projection organization GO:0031344 175 0.035
negative regulation of biosynthetic process GO:0009890 168 0.035
cell projection organization GO:0030030 302 0.034
macromolecular complex assembly GO:0065003 273 0.034
negative regulation of multicellular organismal process GO:0051241 203 0.034
cellular amine metabolic process GO:0044106 38 0.034
chemical homeostasis GO:0048878 292 0.034
amine metabolic process GO:0009308 38 0.034
cellular chemical homeostasis GO:0055082 247 0.034
nucleobase containing small molecule metabolic process GO:0055086 316 0.033
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.032
positive regulation of cell differentiation GO:0045597 217 0.032
apoptotic process GO:0006915 381 0.032
response to oxidative stress GO:0006979 186 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.032
single organism catabolic process GO:0044712 283 0.032
positive regulation of transcription dna templated GO:0045893 197 0.032
metal ion transport GO:0030001 289 0.032
positive regulation of biosynthetic process GO:0009891 319 0.032
regulation of nucleic acid templated transcription GO:1903506 380 0.032
regulation of rna metabolic process GO:0051252 391 0.032
organic acid metabolic process GO:0006082 292 0.030
response to carbohydrate GO:0009743 183 0.030
response to peptide GO:1901652 292 0.030
cellular catabolic process GO:0044248 295 0.029
response to hypoxia GO:0001666 231 0.029
negative regulation of programmed cell death GO:0043069 183 0.029
regulation of transcription dna templated GO:0006355 374 0.029
behavior GO:0007610 205 0.029
positive regulation of rna metabolic process GO:0051254 203 0.029
positive regulation of cell development GO:0010720 176 0.029
cellular response to stress GO:0033554 269 0.028
Human
organophosphate metabolic process GO:0019637 370 0.028
regulation of phosphorus metabolic process GO:0051174 349 0.028
regulation of rna biosynthetic process GO:2001141 381 0.028
response to decreased oxygen levels GO:0036293 237 0.027
cation transport GO:0006812 382 0.027
circulatory system process GO:0003013 183 0.027
positive regulation of nervous system development GO:0051962 178 0.027
multi organism reproductive process GO:0044703 262 0.027
regulation of cellular ketone metabolic process GO:0010565 27 0.027
regulation of cellular amine metabolic process GO:0033238 8 0.027
neurological system process GO:0050877 219 0.027
protein complex biogenesis GO:0070271 263 0.026
positive regulation of nucleic acid templated transcription GO:1903508 197 0.026
negative regulation of cell death GO:0060548 229 0.025
carboxylic acid metabolic process GO:0019752 289 0.025
blood circulation GO:0008015 183 0.025
cellular ketone metabolic process GO:0042180 51 0.025
secretion GO:0046903 307 0.025
cellular component biogenesis GO:0044085 368 0.024
regulation of catalytic activity GO:0050790 304 0.024
homeostatic process GO:0042592 331 0.024
response to nutrient GO:0007584 248 0.024
positive regulation of cell death GO:0010942 184 0.024
cellular response to oxygen containing compound GO:1901701 386 0.024
tissue development GO:0009888 252 0.024
regulation of apoptotic process GO:0042981 335 0.024
cellular component assembly GO:0022607 360 0.024
regulation of molecular function GO:0065009 398 0.023
nucleotide metabolic process GO:0009117 279 0.023
protein complex subunit organization GO:0071822 302 0.023
regulation of protein modification process GO:0031399 194 0.023
metal ion homeostasis GO:0055065 186 0.023
defense response GO:0006952 194 0.023
transcription dna templated GO:0006351 377 0.023
ion transmembrane transport GO:0034220 365 0.023
cellular cation homeostasis GO:0030003 180 0.023
neuron projection development GO:0031175 273 0.023
nucleoside phosphate metabolic process GO:0006753 283 0.023
positive regulation of cell proliferation GO:0008284 249 0.023
positive regulation of phosphorus metabolic process GO:0010562 262 0.023
nucleobase containing compound catabolic process GO:0034655 152 0.023
brain development GO:0007420 247 0.023
response to oxygen levels GO:0070482 265 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.022
protein phosphorylation GO:0006468 345 0.022
response to inorganic substance GO:0010035 377 0.022
cellular metal ion homeostasis GO:0006875 172 0.022
positive regulation of neuron differentiation GO:0045666 126 0.022
cell type specific apoptotic process GO:0097285 134 0.022
positive regulation of rna biosynthetic process GO:1902680 197 0.022
aromatic compound catabolic process GO:0019439 168 0.022
response to peptide hormone GO:0043434 278 0.022
secretion by cell GO:0032940 248 0.022
purine nucleotide metabolic process GO:0006163 229 0.022
rna metabolic process GO:0016070 406 0.022
reproduction GO:0000003 245 0.022
protein localization GO:0008104 191 0.021
single organism reproductive process GO:0044702 297 0.021
heterocycle catabolic process GO:0046700 167 0.021
transmembrane transport GO:0055085 412 0.021
response to glucose GO:0009749 136 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.020
regulation of signal transduction GO:0009966 318 0.020
ion homeostasis GO:0050801 212 0.020
regulation of system process GO:0044057 208 0.020
regulation of response to stress GO:0080134 126 0.020
negative regulation of cellular biosynthetic process GO:0031327 161 0.020
response to extracellular stimulus GO:0009991 380 0.020
regulation of hydrolase activity GO:0051336 143 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
single organism biosynthetic process GO:0044711 342 0.020
positive regulation of protein metabolic process GO:0051247 178 0.020
positive regulation of phosphate metabolic process GO:0045937 262 0.020
negative regulation of gene expression GO:0010629 199 0.019
multicellular organism reproduction GO:0032504 233 0.019
response to hexose GO:0009746 144 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
regulation of neuron projection development GO:0010975 161 0.019
cellular nitrogen compound catabolic process GO:0044270 163 0.019
purine containing compound metabolic process GO:0072521 253 0.019
intracellular transport GO:0046907 185 0.019
regulation of cell motility GO:2000145 131 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.019
positive regulation of neuron projection development GO:0010976 99 0.019
immune system process GO:0002376 204 0.019
divalent inorganic cation homeostasis GO:0072507 165 0.018
regulation of secretion by cell GO:1903530 208 0.018
proteolysis GO:0006508 175 0.018
regulation of catabolic process GO:0009894 113 0.018
neuron death GO:0070997 127 0.018
cation homeostasis GO:0055080 195 0.018
head development GO:0060322 247 0.018
response to reactive oxygen species GO:0000302 120 0.018
regulation of ion transport GO:0043269 245 0.018
synaptic transmission GO:0007268 235 0.018
positive regulation of cell projection organization GO:0031346 111 0.018
central nervous system development GO:0007417 311 0.018
regulation of protein metabolic process GO:0051246 289 0.017
organophosphate catabolic process GO:0046434 148 0.017
ribonucleoside metabolic process GO:0009119 174 0.017
synaptic growth at neuromuscular junction GO:0051124 1 0.017
rhythmic process GO:0048511 156 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
locomotion GO:0040011 237 0.017
chromosome segregation GO:0007059 2 0.017
positive regulation of developmental process GO:0051094 283 0.016
carbohydrate derivative catabolic process GO:1901136 147 0.016
regulation of neuron death GO:1901214 115 0.016
response to acid chemical GO:0001101 222 0.016
regulation of neuron apoptotic process GO:0043523 83 0.016
dna metabolic process GO:0006259 96 0.016
Human
positive regulation of cellular component organization GO:0051130 200 0.016
negative regulation of apoptotic process GO:0043066 181 0.016
peptidyl amino acid modification GO:0018193 126 0.016
negative regulation of cell communication GO:0010648 158 0.016
single organism intracellular transport GO:1902582 166 0.016
regulation of metal ion transport GO:0010959 118 0.016
response to growth factor GO:0070848 189 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.016
reproductive process GO:0022414 372 0.016
glycosyl compound metabolic process GO:1901657 182 0.015
response to metal ion GO:0010038 253 0.015
cellular response to oxidative stress GO:0034599 76 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.015
sensory perception GO:0007600 101 0.015
localization of cell GO:0051674 202 0.015
response to hydrogen peroxide GO:0042542 89 0.015
response to monosaccharide GO:0034284 159 0.015
cellular ion homeostasis GO:0006873 184 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
single organism organelle organization GO:1902589 180 0.015
eye morphogenesis GO:0048592 4 0.015
vascular process in circulatory system GO:0003018 96 0.015
response to ketone GO:1901654 182 0.015
cell cell signaling GO:0007267 335 0.015
regulation of protein phosphorylation GO:0001932 183 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
neuron development GO:0048666 286 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.014
positive regulation of apoptotic process GO:0043065 154 0.014
purine nucleotide catabolic process GO:0006195 136 0.014
transcription from rna polymerase ii promoter GO:0006366 252 0.014
macromolecule localization GO:0033036 252 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
cell cycle checkpoint GO:0000075 2 0.014
calcium ion homeostasis GO:0055074 162 0.014
positive regulation of transport GO:0051050 245 0.014
cellular response to endogenous stimulus GO:0071495 377 0.014
nucleotide catabolic process GO:0009166 139 0.014
signal release GO:0023061 145 0.014
cellular response to growth factor stimulus GO:0071363 162 0.014
negative regulation of rna biosynthetic process GO:1902679 118 0.014
ribonucleotide metabolic process GO:0009259 231 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
response to ionizing radiation GO:0010212 59 0.014
purine ribonucleoside catabolic process GO:0046130 124 0.014
inflammatory response GO:0006954 150 0.014
anterior posterior pattern specification GO:0009952 1 0.014
regulation of phosphorylation GO:0042325 248 0.014
neuron apoptotic process GO:0051402 88 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
alpha amino acid metabolic process GO:1901605 71 0.013
carbohydrate metabolic process GO:0005975 130 0.013
response to biotic stimulus GO:0009607 226 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
response to estrogen GO:0043627 232 0.013
regulation of response to external stimulus GO:0032101 106 0.013
response to mechanical stimulus GO:0009612 134 0.013
positive regulation of molecular function GO:0044093 230 0.013
muscle tissue development GO:0060537 58 0.013
ras protein signal transduction GO:0007265 29 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
protein modification by small protein conjugation or removal GO:0070647 35 0.013
response to vitamin GO:0033273 131 0.013
ribonucleoside triphosphate catabolic process GO:0009203 122 0.013
response to estradiol GO:0032355 164 0.013
regulation of intracellular signal transduction GO:1902531 218 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
cellular response to peptide GO:1901653 133 0.013
response to ethanol GO:0045471 162 0.013
response to nutrient levels GO:0031667 370 0.012
positive regulation of nucleotide metabolic process GO:0045981 91 0.012
regulation of blood circulation GO:1903522 110 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
regulation of smooth muscle cell proliferation GO:0048660 75 0.012
regulation of vesicle mediated transport GO:0060627 81 0.012
gamete generation GO:0007276 124 0.012
response to purine containing compound GO:0014074 126 0.012
regulation of tube size GO:0035150 89 0.012
gtp metabolic process GO:0046039 72 0.012
regulation of cellular localization GO:0060341 263 0.012
response to wounding GO:0009611 254 0.012
response to external biotic stimulus GO:0043207 221 0.012
aging GO:0007568 241 0.012
nucleoside catabolic process GO:0009164 126 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
positive regulation of response to stimulus GO:0048584 285 0.012
female pregnancy GO:0007565 122 0.012
nitrogen compound transport GO:0071705 229 0.012
response to amino acid GO:0043200 75 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
protein oligomerization GO:0051259 191 0.011
wound healing GO:0042060 122 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
positive regulation of cell migration GO:0030335 96 0.011
vesicle mediated transport GO:0016192 181 0.011
retina morphogenesis in camera type eye GO:0060042 1 0.011
cell cycle GO:0007049 101 0.011
multi multicellular organism process GO:0044706 138 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
circulatory system development GO:0072359 134 0.011
regulation of fat cell differentiation GO:0045598 3 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
development of primary sexual characteristics GO:0045137 107 0.011
negative regulation of rna metabolic process GO:0051253 123 0.011
regulation of growth GO:0040008 105 0.011
cytoskeleton organization GO:0007010 111 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
cellular response to lipid GO:0071396 201 0.011
cellular response to external stimulus GO:0071496 118 0.011
salivary gland morphogenesis GO:0007435 1 0.011
muscle system process GO:0003012 115 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
nucleoside metabolic process GO:0009116 179 0.011
cardiovascular system development GO:0072358 134 0.011
positive regulation of cell motility GO:2000147 97 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
regulation of cellular catabolic process GO:0031329 101 0.011
maintenance of location GO:0051235 17 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
cellular macromolecular complex assembly GO:0034622 58 0.011
spermatogenesis GO:0007283 99 0.011
regulation of immune system process GO:0002682 123 0.010
response to organophosphorus GO:0046683 102 0.010
nucleotide biosynthetic process GO:0009165 98 0.010
smooth muscle cell proliferation GO:0048659 77 0.010
sex differentiation GO:0007548 113 0.010
sexual reproduction GO:0019953 148 0.010
negative regulation of cell cycle phase transition GO:1901988 4 0.010
positive regulation of phosphorylation GO:0042327 177 0.010
regulation of membrane potential GO:0042391 110 0.010
regulation of locomotion GO:0040012 148 0.010
histone modification GO:0016570 30 0.010
purine nucleoside catabolic process GO:0006152 124 0.010
cytoplasmic transport GO:0016482 115 0.010
regeneration GO:0031099 163 0.010
response to cytokine GO:0034097 215 0.010
axis specification GO:0009798 4 0.010
cell migration GO:0016477 197 0.010
positive regulation of cell communication GO:0010647 271 0.010
hormone secretion GO:0046879 115 0.010
organophosphate biosynthetic process GO:0090407 143 0.010
negative regulation of molecular function GO:0044092 133 0.010

Polk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
musculoskeletal system disease DOID:17 0 0.025
nervous system disease DOID:863 0 0.021
sensory system disease DOID:0050155 0 0.014
disease of metabolism DOID:0014667 0 0.013