Rattus norvegicus

29 known processes

Aurka

aurora kinase A

(Aliases: Stk6,MGC124935)

Aurka biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
protein complex assembly GO:0006461 263 0.121
Yeast Mouse Worm
macromolecular complex assembly GO:0065003 273 0.101
Yeast Mouse Worm
cellular component assembly GO:0022607 360 0.067
Yeast Mouse Worm
meiotic cell cycle process GO:1903046 3 0.064
Yeast Mouse
cellular component biogenesis GO:0044085 368 0.063
Yeast Mouse Worm
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.061
spindle organization GO:0007051 2 0.055
Human Yeast Mouse Worm
macromolecular complex subunit organization GO:0043933 339 0.053
Human Yeast Mouse Worm
chromosome segregation GO:0007059 2 0.053
Yeast Worm
regulation of chromosome segregation GO:0051983 1 0.049
protein complex subunit organization GO:0071822 302 0.048
Human Yeast Mouse Worm
regulation of molecular function GO:0065009 398 0.045
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.042
regulation of phosphate metabolic process GO:0019220 349 0.042
regulation of protein metabolic process GO:0051246 289 0.041
Mouse
chromosome condensation GO:0030261 3 0.039
Worm
regulation of phosphorus metabolic process GO:0051174 349 0.039
mitotic sister chromatid separation GO:0051306 1 0.038
reproductive process GO:0022414 372 0.038
Mouse Worm
cytoskeleton organization GO:0007010 111 0.038
Human Yeast Mouse Worm
regulation of proteasomal protein catabolic process GO:0061136 4 0.036
Mouse
meiosis i GO:0007127 2 0.035
Yeast Mouse
macromolecule localization GO:0033036 252 0.035
Yeast Mouse Worm
organelle organization GO:0006996 266 0.034
Human Yeast Zebrafish Mouse Worm
positive regulation of phosphate metabolic process GO:0045937 262 0.033
single organism reproductive process GO:0044702 297 0.032
Mouse Worm
regulation of organelle organization GO:0033043 80 0.032
Human Yeast
cell cycle checkpoint GO:0000075 2 0.032
Yeast Mouse
protein phosphorylation GO:0006468 345 0.031
cellular amine metabolic process GO:0044106 38 0.031
regulation of multicellular organismal development GO:2000026 376 0.030
central nervous system development GO:0007417 311 0.030
regulation of catalytic activity GO:0050790 304 0.030
cellular response to oxygen containing compound GO:1901701 386 0.029
rna metabolic process GO:0016070 406 0.028
positive regulation of cell proliferation GO:0008284 249 0.028
amine metabolic process GO:0009308 38 0.028
negative regulation of macromolecule metabolic process GO:0010605 260 0.028
multicellular organismal reproductive process GO:0048609 233 0.028
Mouse
cell cycle GO:0007049 101 0.028
Human Yeast Zebrafish Mouse Worm
dna packaging GO:0006323 4 0.027
Worm
apoptotic process GO:0006915 381 0.027
Mouse
cytoskeleton dependent cytokinesis GO:0061640 2 0.027
Worm
regulation of cell proliferation GO:0042127 359 0.027
protein complex biogenesis GO:0070271 263 0.026
Yeast Mouse Worm
sister chromatid segregation GO:0000819 1 0.026
Yeast
multi organism reproductive process GO:0044703 262 0.026
Mouse
cellular ketone metabolic process GO:0042180 51 0.026
nucleobase containing small molecule metabolic process GO:0055086 316 0.026
positive regulation of protein modification process GO:0031401 142 0.025
mitotic spindle organization GO:0007052 2 0.025
Yeast Mouse Worm
positive regulation of rna metabolic process GO:0051254 203 0.025
single organism organelle organization GO:1902589 180 0.025
Human Yeast Zebrafish Mouse Worm
developmental process involved in reproduction GO:0003006 159 0.025
Mouse Worm
regulation of cellular amine metabolic process GO:0033238 8 0.025
multicellular organism reproduction GO:0032504 233 0.024
Mouse
response to decreased oxygen levels GO:0036293 237 0.024
transcription from rna polymerase ii promoter GO:0006366 252 0.024
cellular component movement GO:0006928 248 0.024
organic substance catabolic process GO:1901575 316 0.024
Mouse
single organism biosynthetic process GO:0044711 342 0.023
mitotic sister chromatid segregation GO:0000070 1 0.023
negative regulation of cellular biosynthetic process GO:0031327 161 0.023
maintenance of location GO:0051235 17 0.023
Yeast
oxoacid metabolic process GO:0043436 290 0.023
positive regulation of biosynthetic process GO:0009891 319 0.023
negative regulation of cellular metabolic process GO:0031324 281 0.022
response to hypoxia GO:0001666 231 0.022
positive regulation of multicellular organismal process GO:0051240 387 0.022
Mouse
positive regulation of gene expression GO:0010628 244 0.022
regulation of protein phosphorylation GO:0001932 183 0.022
cellular response to stress GO:0033554 269 0.022
carboxylic acid metabolic process GO:0019752 289 0.022
positive regulation of phosphorus metabolic process GO:0010562 262 0.022
regulation of cellular protein metabolic process GO:0032268 267 0.021
Mouse
tissue development GO:0009888 252 0.021
regulation of protein modification process GO:0031399 194 0.021
purine containing compound metabolic process GO:0072521 253 0.021
programmed cell death GO:0012501 392 0.021
Mouse
transcription dna templated GO:0006351 377 0.021
regulation of rna metabolic process GO:0051252 391 0.021
cell cell signaling GO:0007267 335 0.021
regulation of cell differentiation GO:0045595 320 0.021
Mouse
rna biosynthetic process GO:0032774 380 0.020
intracellular signal transduction GO:0035556 314 0.020
regulation of phosphorylation GO:0042325 248 0.020
neuron differentiation GO:0030182 368 0.020
Mouse
regulation of cell cycle GO:0051726 73 0.020
Human Yeast Mouse Worm
regulation of cellular localization GO:0060341 263 0.020
Yeast
negative regulation of cell cycle phase transition GO:1901988 4 0.019
Yeast
positive regulation of phosphorylation GO:0042327 177 0.019
response to estrogen GO:0043627 232 0.019
organic acid metabolic process GO:0006082 292 0.019
negative regulation of cell death GO:0060548 229 0.019
Mouse
response to oxygen levels GO:0070482 265 0.019
sexual reproduction GO:0019953 148 0.019
Mouse
regulation of cellular component organization GO:0051128 368 0.019
Human Yeast
negative regulation of gene expression GO:0010629 199 0.019
nucleotide metabolic process GO:0009117 279 0.019
mitotic cell cycle phase transition GO:0044772 20 0.019
Yeast
nucleoside phosphate metabolic process GO:0006753 283 0.019
regulation of cellular amino acid metabolic process GO:0006521 2 0.019
chromatin modification GO:0016568 33 0.019
Mouse
metaphase anaphase transition of cell cycle GO:0044784 1 0.018
regeneration GO:0031099 163 0.018
cellular amino acid metabolic process GO:0006520 107 0.018
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 1 0.018
negative regulation of metabolic process GO:0009892 331 0.018
organophosphate metabolic process GO:0019637 370 0.018
organelle localization GO:0051640 55 0.018
Mouse
cellular catabolic process GO:0044248 295 0.017
Mouse
cell cycle process GO:0022402 57 0.017
Human Yeast Zebrafish Mouse Worm
response to acid chemical GO:0001101 222 0.017
metaphase anaphase transition of mitotic cell cycle GO:0007091 1 0.017
regulation of signal transduction GO:0009966 318 0.017
negative regulation of cell communication GO:0010648 158 0.017
proteolysis GO:0006508 175 0.017
Mouse
dna replication GO:0006260 37 0.017
response to fatty acid GO:0070542 65 0.017
anterior posterior pattern specification GO:0009952 1 0.016
Mouse
negative regulation of cellular protein metabolic process GO:0032269 106 0.016
regulation of programmed cell death GO:0043067 341 0.016
Mouse
regulation of mitotic sister chromatid separation GO:0010965 1 0.016
positive regulation of cellular biosynthetic process GO:0031328 295 0.016
response to purine containing compound GO:0014074 126 0.016
catabolic process GO:0009056 351 0.016
Mouse
positive regulation of molecular function GO:0044093 230 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
response to inorganic substance GO:0010035 377 0.016
cellular response to acid chemical GO:0071229 75 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.016
regulation of mitotic sister chromatid segregation GO:0033047 1 0.016
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.015
Yeast
circulatory system development GO:0072359 134 0.015
carbohydrate derivative metabolic process GO:1901135 346 0.015
locomotion GO:0040011 237 0.015
Worm
regulation of nucleic acid templated transcription GO:1903506 380 0.015
microtubule anchoring GO:0034453 1 0.015
Yeast
regulation of sister chromatid segregation GO:0033045 1 0.015
head development GO:0060322 247 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
reproduction GO:0000003 245 0.015
Yeast Mouse Worm
ribose phosphate metabolic process GO:0019693 235 0.015
positive regulation of rna biosynthetic process GO:1902680 197 0.015
purine nucleotide metabolic process GO:0006163 229 0.014
centrosome organization GO:0051297 1 0.014
Mouse
cell projection organization GO:0030030 302 0.014
Mouse
wound healing GO:0042060 122 0.014
response to metal ion GO:0010038 253 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
spermatogenesis GO:0007283 99 0.014
response to ddt GO:0046680 1 0.014
regulation of transcription dna templated GO:0006355 374 0.014
positive regulation of cellular protein metabolic process GO:0032270 167 0.014
Mouse
response to mechanical stimulus GO:0009612 134 0.014
male gamete generation GO:0048232 99 0.014
single organism catabolic process GO:0044712 283 0.014
cellular response to endogenous stimulus GO:0071495 377 0.014
Yeast
negative regulation of microtubule depolymerization GO:0007026 3 0.014
Human
double strand break repair GO:0006302 1 0.014
peptidyl amino acid modification GO:0018193 126 0.014
Mouse Worm
regulation of growth GO:0040008 105 0.014
nucleic acid templated transcription GO:0097659 379 0.014
anatomical structure morphogenesis GO:0009653 298 0.014
Mouse
regulation of nervous system development GO:0051960 264 0.014
cellular macromolecule localization GO:0070727 122 0.014
Yeast Mouse
chromosome separation GO:0051304 1 0.013
homeostatic process GO:0042592 331 0.013
gamete generation GO:0007276 124 0.013
Mouse
regulation of dna metabolic process GO:0051052 60 0.013
dephosphorylation GO:0016311 98 0.013
regulation of kinase activity GO:0043549 117 0.013
regulation of transferase activity GO:0051338 123 0.013
heterocycle catabolic process GO:0046700 167 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
Mouse
purine ribonucleoside metabolic process GO:0046128 168 0.013
ribonucleoside metabolic process GO:0009119 174 0.013
mrna 3 end processing GO:0031124 1 0.013
regulation of rna biosynthetic process GO:2001141 381 0.013
cellular response to lipid GO:0071396 201 0.013
developmental growth GO:0048589 100 0.013
Mouse
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
regulation of neurogenesis GO:0050767 247 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
Mouse
histone phosphorylation GO:0016572 6 0.013
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
histone serine phosphorylation GO:0035404 1 0.012
Mouse
positive regulation of developmental process GO:0051094 283 0.012
Mouse
ras protein signal transduction GO:0007265 29 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
negative regulation of molecular function GO:0044092 133 0.012
Human
ribonucleotide metabolic process GO:0009259 231 0.012
positive regulation of nervous system development GO:0051962 178 0.012
regulation of protein localization GO:0032880 81 0.012
Yeast
regulation of cell projection organization GO:0031344 175 0.012
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
cellular protein localization GO:0034613 122 0.012
Yeast Mouse
protein localization GO:0008104 191 0.012
Yeast Mouse Worm
regulation of catabolic process GO:0009894 113 0.012
Mouse
axis specification GO:0009798 4 0.012
Mouse
regulation of mrna 3 end processing GO:0031440 1 0.012
vesicle mediated transport GO:0016192 181 0.012
mitotic cell cycle process GO:1903047 35 0.012
Yeast Zebrafish Mouse Worm
negative regulation of protein metabolic process GO:0051248 114 0.012
cellular response to organic cyclic compound GO:0071407 202 0.012
positive regulation of protein phosphorylation GO:0001934 135 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
response to lipopolysaccharide GO:0032496 191 0.012
regulation of cardiac muscle tissue development GO:0055024 12 0.012
monovalent inorganic cation transport GO:0015672 172 0.012
cardiovascular system development GO:0072358 134 0.011
regulation of apoptotic process GO:0042981 335 0.011
Mouse
establishment of organelle localization GO:0051656 37 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
cellular homeostasis GO:0019725 252 0.011
regulation of neuron projection development GO:0010975 161 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
negative regulation of signaling GO:0023057 157 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.011
cell cycle phase transition GO:0044770 21 0.011
Yeast
brain development GO:0007420 247 0.011
protein oligomerization GO:0051259 191 0.011
establishment of chromosome localization GO:0051303 1 0.011
metaphase plate congression GO:0051310 1 0.011
aging GO:0007568 241 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
chemical homeostasis GO:0048878 292 0.011
positive regulation of cell differentiation GO:0045597 217 0.011
Mouse
macromolecule catabolic process GO:0009057 58 0.011
Mouse
cellular response to abiotic stimulus GO:0071214 85 0.011
positive regulation of transcription dna templated GO:0045893 197 0.010
nucleoside triphosphate metabolic process GO:0009141 144 0.010
digestive tract development GO:0048565 39 0.010
mitotic cell cycle checkpoint GO:0007093 1 0.010
Yeast
cell growth GO:0016049 104 0.010
Mouse
muscle cell proliferation GO:0033002 84 0.010
neuron development GO:0048666 286 0.010
Mouse
lipid metabolic process GO:0006629 283 0.010

Aurka disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
disease of metabolism DOID:0014667 0 0.012