Rattus norvegicus

39 known processes

Dhh

desert hedgehog homolog (Drosophila)

Dhh biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
anatomical structure morphogenesis GO:0009653 298 0.166
Rat
rna biosynthetic process GO:0032774 380 0.088
Rat
single organism biosynthetic process GO:0044711 342 0.067
protein complex assembly GO:0006461 263 0.067
regulation of nucleic acid templated transcription GO:1903506 380 0.065
Rat
blood circulation GO:0008015 183 0.063
macromolecular complex assembly GO:0065003 273 0.062
regulation of rna metabolic process GO:0051252 391 0.061
Rat
regulation of rna biosynthetic process GO:2001141 381 0.053
Rat
organophosphate metabolic process GO:0019637 370 0.052
cellular homeostasis GO:0019725 252 0.049
nucleic acid templated transcription GO:0097659 379 0.048
Rat
chemical homeostasis GO:0048878 292 0.048
cellular ion homeostasis GO:0006873 184 0.047
transcription from rna polymerase ii promoter GO:0006366 252 0.046
Rat
rna metabolic process GO:0016070 406 0.045
Rat
response to inorganic substance GO:0010035 377 0.043
regulation of phosphorus metabolic process GO:0051174 349 0.043
carbohydrate derivative metabolic process GO:1901135 346 0.043
cellular component assembly GO:0022607 360 0.042
organic substance catabolic process GO:1901575 316 0.041
purine nucleotide metabolic process GO:0006163 229 0.041
cellular catabolic process GO:0044248 295 0.040
nucleobase containing small molecule metabolic process GO:0055086 316 0.040
intracellular signal transduction GO:0035556 314 0.040
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.040
Rat
lipid metabolic process GO:0006629 283 0.040
anion transport GO:0006820 178 0.040
regulation of transcription dna templated GO:0006355 374 0.040
Rat
response to nutrient levels GO:0031667 370 0.039
nucleoside phosphate metabolic process GO:0006753 283 0.038
central nervous system development GO:0007417 311 0.038
Rat
response to peptide hormone GO:0043434 278 0.038
nucleotide metabolic process GO:0009117 279 0.038
oxoacid metabolic process GO:0043436 290 0.038
positive regulation of cellular biosynthetic process GO:0031328 295 0.037
Rat
positive regulation of phosphate metabolic process GO:0045937 262 0.037
regulation of hormone levels GO:0010817 187 0.037
positive regulation of gene expression GO:0010628 244 0.036
Rat
divalent inorganic cation homeostasis GO:0072507 165 0.036
purine ribonucleoside metabolic process GO:0046128 168 0.035
transcription dna templated GO:0006351 377 0.035
Rat
macromolecular complex subunit organization GO:0043933 339 0.035
organic acid metabolic process GO:0006082 292 0.034
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.034
Rat
catabolic process GO:0009056 351 0.034
positive regulation of nucleic acid templated transcription GO:1903508 197 0.034
Rat
regulation of catalytic activity GO:0050790 304 0.033
calcium ion homeostasis GO:0055074 162 0.033
small molecule biosynthetic process GO:0044283 124 0.033
purine containing compound metabolic process GO:0072521 253 0.032
homeostatic process GO:0042592 331 0.032
single organism reproductive process GO:0044702 297 0.032
Rat
cellular metal ion homeostasis GO:0006875 172 0.031
protein oligomerization GO:0051259 191 0.031
single organism catabolic process GO:0044712 283 0.031
regulation of protein modification process GO:0031399 194 0.031
cellular divalent inorganic cation homeostasis GO:0072503 162 0.030
macromolecule localization GO:0033036 252 0.030
ribose phosphate metabolic process GO:0019693 235 0.030
aging GO:0007568 241 0.030
cellular amino acid metabolic process GO:0006520 107 0.030
cellular calcium ion homeostasis GO:0006874 160 0.029
organic anion transport GO:0015711 132 0.029
metal ion homeostasis GO:0055065 186 0.029
regulation of phosphate metabolic process GO:0019220 349 0.029
positive regulation of signaling GO:0023056 270 0.029
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.029
regulation of cell differentiation GO:0045595 320 0.028
Rat
cellular response to oxygen containing compound GO:1901701 386 0.028
cytosolic calcium ion homeostasis GO:0051480 140 0.028
protein phosphorylation GO:0006468 345 0.028
cation homeostasis GO:0055080 195 0.028
head development GO:0060322 247 0.028
Rat
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.028
Rat
cellular component biogenesis GO:0044085 368 0.028
protein complex subunit organization GO:0071822 302 0.028
regulation of cellular protein metabolic process GO:0032268 267 0.028
immune system process GO:0002376 204 0.027
protein complex biogenesis GO:0070271 263 0.027
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.027
Rat
purine nucleoside metabolic process GO:0042278 169 0.027
hormone metabolic process GO:0042445 69 0.027
ribonucleotide metabolic process GO:0009259 231 0.027
positive regulation of catalytic activity GO:0043085 184 0.026
regulation of molecular function GO:0065009 398 0.025
positive regulation of molecular function GO:0044093 230 0.025
regulation of cellular localization GO:0060341 263 0.025
ion homeostasis GO:0050801 212 0.025
negative regulation of biosynthetic process GO:0009890 168 0.025
biological adhesion GO:0022610 110 0.025
organic acid biosynthetic process GO:0016053 83 0.025
positive regulation of rna metabolic process GO:0051254 203 0.025
Rat
positive regulation of rna biosynthetic process GO:1902680 197 0.024
Rat
purine ribonucleotide metabolic process GO:0009150 227 0.024
regulation of multicellular organismal development GO:2000026 376 0.024
Rat
regulation of protein metabolic process GO:0051246 289 0.024
regulation of signal transduction GO:0009966 318 0.024
Rat
negative regulation of metabolic process GO:0009892 331 0.023
regulation of purine nucleotide metabolic process GO:1900542 115 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.023
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.023
neurological system process GO:0050877 219 0.022
brain development GO:0007420 247 0.022
Rat
positive regulation of cell communication GO:0010647 271 0.022
ion transmembrane transport GO:0034220 365 0.022
positive regulation of intracellular signal transduction GO:1902533 138 0.022
programmed cell death GO:0012501 392 0.022
Rat
purine nucleotide catabolic process GO:0006195 136 0.021
protein localization GO:0008104 191 0.021
metal ion transport GO:0030001 289 0.021
positive regulation of biosynthetic process GO:0009891 319 0.021
Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.021
cellular response to organic cyclic compound GO:0071407 202 0.021
response to extracellular stimulus GO:0009991 380 0.020
positive regulation of cell differentiation GO:0045597 217 0.020
Rat
cellular lipid metabolic process GO:0044255 208 0.020
cellular response to lipid GO:0071396 201 0.020
response to peptide GO:1901652 292 0.020
glycosyl compound metabolic process GO:1901657 182 0.020
cellular response to endogenous stimulus GO:0071495 377 0.020
organic hydroxy compound metabolic process GO:1901615 115 0.020
regulation of canonical wnt signaling pathway GO:0060828 4 0.020
tissue development GO:0009888 252 0.020
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.020
transmembrane transport GO:0055085 412 0.020
positive regulation of transcription dna templated GO:0045893 197 0.020
Rat
positive regulation of multicellular organismal process GO:0051240 387 0.019
Rat
regulation of protein phosphorylation GO:0001932 183 0.019
amine metabolic process GO:0009308 38 0.019
cellular chemical homeostasis GO:0055082 247 0.019
negative regulation of cell communication GO:0010648 158 0.019
Rat
regulation of cellular ketone metabolic process GO:0010565 27 0.019
response to metal ion GO:0010038 253 0.019
positive regulation of protein modification process GO:0031401 142 0.019
cell adhesion GO:0007155 110 0.019
ribonucleoside metabolic process GO:0009119 174 0.019
secretion GO:0046903 307 0.018
reproduction GO:0000003 245 0.018
Rat
organelle organization GO:0006996 266 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
nucleoside metabolic process GO:0009116 179 0.018
organic cyclic compound catabolic process GO:1901361 175 0.018
inorganic ion transmembrane transport GO:0098660 229 0.018
fatty acid metabolic process GO:0006631 99 0.018
single organism intracellular transport GO:1902582 166 0.018
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
anion transmembrane transport GO:0098656 77 0.017
carboxylic acid metabolic process GO:0019752 289 0.017
circulatory system process GO:0003013 183 0.017
signal release GO:0023061 145 0.017
eye morphogenesis GO:0048592 4 0.017
negative regulation of transport GO:0051051 136 0.017
cation transport GO:0006812 382 0.017
positive regulation of signal transduction GO:0009967 175 0.017
single organism organelle organization GO:1902589 180 0.017
ribonucleotide catabolic process GO:0009261 136 0.017
regulation of protein kinase activity GO:0045859 105 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
organonitrogen compound catabolic process GO:1901565 179 0.016
negative regulation of macromolecule metabolic process GO:0010605 260 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
nucleoside catabolic process GO:0009164 126 0.016
cellular amine metabolic process GO:0044106 38 0.016
regulation of ion transport GO:0043269 245 0.016
aromatic compound catabolic process GO:0019439 168 0.016
nucleoside phosphate biosynthetic process GO:1901293 102 0.016
heterocycle catabolic process GO:0046700 167 0.016
response to oxidative stress GO:0006979 186 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
multicellular organism reproduction GO:0032504 233 0.016
Rat
amino acid transmembrane transport GO:0003333 33 0.015
regulation of programmed cell death GO:0043067 341 0.015
Rat
monovalent inorganic cation transport GO:0015672 172 0.015
positive regulation of cellular amine metabolic process GO:0033240 3 0.015
nitrogen compound transport GO:0071705 229 0.015
regulation of cellular component organization GO:0051128 368 0.015
dna metabolic process GO:0006259 96 0.015
cellular hormone metabolic process GO:0034754 49 0.015
sexual reproduction GO:0019953 148 0.015
Rat
regulation of apoptotic process GO:0042981 335 0.015
Rat
regulation of immune system process GO:0002682 123 0.015
response to ketone GO:1901654 182 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.014
regulation of nucleotide metabolic process GO:0006140 117 0.014
cellular protein localization GO:0034613 122 0.014
multi organism reproductive process GO:0044703 262 0.014
Rat
negative regulation of cell death GO:0060548 229 0.014
Rat
response to acid chemical GO:0001101 222 0.014
Rat
nucleobase containing compound catabolic process GO:0034655 152 0.014
purine containing compound biosynthetic process GO:0072522 85 0.014
regulation of g0 to g1 transition GO:0070316 3 0.014
hormone transport GO:0009914 121 0.014
glycosyl compound catabolic process GO:1901658 126 0.014
response to fatty acid GO:0070542 65 0.014
purine containing compound catabolic process GO:0072523 138 0.014
carboxylic acid transport GO:0046942 115 0.014
cellular ketone metabolic process GO:0042180 51 0.013
protein heterooligomerization GO:0051291 89 0.013
negative regulation of signaling GO:0023057 157 0.013
Rat
alcohol metabolic process GO:0006066 77 0.013
reproductive process GO:0022414 372 0.013
Rat
carboxylic acid biosynthetic process GO:0046394 83 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
Rat
regulation of cell development GO:0060284 263 0.013
Rat
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
negative regulation of cellular metabolic process GO:0031324 281 0.013
locomotion GO:0040011 237 0.013
cell cell signaling GO:0007267 335 0.013
regulation of kinase activity GO:0043549 117 0.013
neuron development GO:0048666 286 0.013
positive regulation of developmental process GO:0051094 283 0.013
Rat
secretion by cell GO:0032940 248 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
regulation of cellular amine metabolic process GO:0033238 8 0.013
response to nutrient GO:0007584 248 0.013
cation transmembrane transport GO:0098655 263 0.013
apoptotic process GO:0006915 381 0.013
Rat
regulation of phosphorylation GO:0042325 248 0.013
anterior posterior pattern specification GO:0009952 1 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
negative regulation of cellular biosynthetic process GO:0031327 161 0.013
reproductive system development GO:0061458 128 0.012
Rat
cellular cation homeostasis GO:0030003 180 0.012
positive regulation of response to stimulus GO:0048584 285 0.012
positive regulation of cellular component organization GO:0051130 200 0.012
antigen processing and presentation GO:0019882 2 0.012
cellular response to nitrogen compound GO:1901699 210 0.012
nucleoside triphosphate metabolic process GO:0009141 144 0.012
lipid biosynthetic process GO:0008610 128 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
neuron projection development GO:0031175 273 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
organic acid transport GO:0015849 116 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
development of primary sexual characteristics GO:0045137 107 0.012
epithelium development GO:0060429 96 0.012
Rat
nucleoside phosphate catabolic process GO:1901292 140 0.012
negative regulation of multicellular organismal process GO:0051241 203 0.012
cellular response to acid chemical GO:0071229 75 0.012
negative regulation of rna metabolic process GO:0051253 123 0.011
muscle system process GO:0003012 115 0.011
purine ribonucleoside catabolic process GO:0046130 124 0.011
muscle cell proliferation GO:0033002 84 0.011
nucleotide biosynthetic process GO:0009165 98 0.011
response to estrogen GO:0043627 232 0.011
lipid localization GO:0010876 62 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
Rat
isoprenoid metabolic process GO:0006720 45 0.011
positive regulation of protein phosphorylation GO:0001934 135 0.011
ribose phosphate biosynthetic process GO:0046390 87 0.011
multicellular organismal reproductive process GO:0048609 233 0.011
Rat
heart morphogenesis GO:0003007 3 0.011
response to hydrogen peroxide GO:0042542 89 0.011
regulation of intracellular signal transduction GO:1902531 218 0.011
cellular component morphogenesis GO:0032989 155 0.011
multicellular organism growth GO:0035264 1 0.011
guanosine containing compound metabolic process GO:1901068 74 0.011
cyclic nucleotide metabolic process GO:0009187 80 0.011
regulation of smooth muscle cell proliferation GO:0048660 75 0.011
regulation of locomotion GO:0040012 148 0.011
purine ribonucleotide biosynthetic process GO:0009152 81 0.011
cell projection organization GO:0030030 302 0.011
small molecule catabolic process GO:0044282 59 0.011
cellular component movement GO:0006928 248 0.011
response to anoxia GO:0034059 4 0.011
regulation of bmp signaling pathway GO:0030510 2 0.011
negative regulation of transcription dna templated GO:0045892 116 0.011
guanosine containing compound catabolic process GO:1901069 71 0.010
positive regulation of blood circulation GO:1903524 65 0.010
ras protein signal transduction GO:0007265 29 0.010
organonitrogen compound biosynthetic process GO:1901566 167 0.010
regulation of catabolic process GO:0009894 113 0.010
cellular response to stress GO:0033554 269 0.010
response to glucose GO:0009749 136 0.010
bmp signaling pathway GO:0030509 4 0.010
axis specification GO:0009798 4 0.010
regulation of nervous system development GO:0051960 264 0.010
Rat
response to temperature stimulus GO:0009266 94 0.010
negative regulation of programmed cell death GO:0043069 183 0.010
Rat
response to cytokine GO:0034097 215 0.010
sensory perception of light stimulus GO:0050953 3 0.010
negative regulation of gene expression GO:0010629 199 0.010
regulation of secretion GO:0051046 224 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.010
embryonic pattern specification GO:0009880 1 0.010
cytoskeleton organization GO:0007010 111 0.010
negative regulation of apoptotic process GO:0043066 181 0.010
Rat
cytoplasmic transport GO:0016482 115 0.010

Dhh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
nervous system disease DOID:863 0 0.040
retinal disease DOID:5679 0 0.037
retinal degeneration DOID:8466 0 0.037
sensory system disease DOID:0050155 0 0.037
retinitis pigmentosa DOID:10584 0 0.037
eye and adnexa disease DOID:1492 0 0.037
eye disease DOID:5614 0 0.037
disease of metabolism DOID:0014667 0 0.011