Rattus norvegicus

0 known processes

Helz

helicase with zinc finger

Helz biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription dna templated GO:0006355 374 0.156
nucleic acid templated transcription GO:0097659 379 0.132
regulation of rna metabolic process GO:0051252 391 0.102
cell projection organization GO:0030030 302 0.100
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.089
anatomical structure morphogenesis GO:0009653 298 0.089
rna metabolic process GO:0016070 406 0.067
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.063
regulation of nucleic acid templated transcription GO:1903506 380 0.062
cell morphogenesis involved in differentiation GO:0000904 119 0.048
anterior posterior pattern specification GO:0009952 1 0.047
positive regulation of rna metabolic process GO:0051254 203 0.044
positive regulation of rna biosynthetic process GO:1902680 197 0.044
intracellular signal transduction GO:0035556 314 0.044
regulation of phosphorus metabolic process GO:0051174 349 0.042
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.039
transcription dna templated GO:0006351 377 0.038
nucleoside phosphate metabolic process GO:0006753 283 0.038
organic substance catabolic process GO:1901575 316 0.037
neuron projection development GO:0031175 273 0.035
regulation of neuron differentiation GO:0045664 208 0.035
positive regulation of nucleic acid templated transcription GO:1903508 197 0.034
rna biosynthetic process GO:0032774 380 0.034
regulation of multicellular organismal development GO:2000026 376 0.032
positive regulation of transcription dna templated GO:0045893 197 0.032
regulation of cell projection organization GO:0031344 175 0.031
positive regulation of phosphate metabolic process GO:0045937 262 0.031
nucleotide metabolic process GO:0009117 279 0.031
carbohydrate derivative metabolic process GO:1901135 346 0.029
regulation of kinase activity GO:0043549 117 0.029
axon development GO:0061564 96 0.029
positive regulation of cell differentiation GO:0045597 217 0.028
organophosphate metabolic process GO:0019637 370 0.028
cell cell signaling GO:0007267 335 0.027
positive regulation of neurogenesis GO:0050769 165 0.027
central nervous system development GO:0007417 311 0.027
regulation of anatomical structure morphogenesis GO:0022603 141 0.026
positive regulation of molecular function GO:0044093 230 0.026
positive regulation of cellular biosynthetic process GO:0031328 295 0.026
regulation of system process GO:0044057 208 0.025
regulation of cell differentiation GO:0045595 320 0.025
cell morphogenesis GO:0000902 142 0.024
regulation of purine nucleotide metabolic process GO:1900542 115 0.024
regulation of cell morphogenesis GO:0022604 77 0.024
regulation of protein kinase activity GO:0045859 105 0.024
catabolic process GO:0009056 351 0.024
regulation of rna biosynthetic process GO:2001141 381 0.024
regulation of canonical wnt signaling pathway GO:0060828 4 0.024
reproductive process GO:0022414 372 0.023
regulation of catalytic activity GO:0050790 304 0.023
positive regulation of biosynthetic process GO:0009891 319 0.023
cell part morphogenesis GO:0032990 123 0.023
regulation of protein modification process GO:0031399 194 0.023
bmp signaling pathway GO:0030509 4 0.022
transcription from rna polymerase ii promoter GO:0006366 252 0.022
regulation of molecular function GO:0065009 398 0.022
negative regulation of cellular protein metabolic process GO:0032269 106 0.022
motor neuron axon guidance GO:0008045 1 0.022
multi organism reproductive process GO:0044703 262 0.022
epithelium development GO:0060429 96 0.022
nucleobase containing small molecule metabolic process GO:0055086 316 0.022
nucleobase containing compound catabolic process GO:0034655 152 0.021
regulation of neuron projection development GO:0010975 161 0.021
axis specification GO:0009798 4 0.021
regulation of cellular protein metabolic process GO:0032268 267 0.021
protein phosphorylation GO:0006468 345 0.021
neuron differentiation GO:0030182 368 0.020
growth GO:0040007 165 0.020
positive regulation of nervous system development GO:0051962 178 0.020
negative regulation of phosphorus metabolic process GO:0010563 80 0.020
positive regulation of programmed cell death GO:0043068 157 0.019
inner ear receptor cell differentiation GO:0060113 2 0.019
organelle organization GO:0006996 266 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
neuron projection morphogenesis GO:0048812 122 0.019
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.019
aromatic compound catabolic process GO:0019439 168 0.019
cellular component morphogenesis GO:0032989 155 0.019
gastrulation GO:0007369 2 0.019
negative regulation of phosphate metabolic process GO:0045936 80 0.019
cell projection morphogenesis GO:0048858 123 0.018
dna metabolic process GO:0006259 96 0.018
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.018
regulation of transferase activity GO:0051338 123 0.018
carbohydrate derivative biosynthetic process GO:1901137 124 0.018
negative regulation of protein metabolic process GO:0051248 114 0.017
regulation of phosphate metabolic process GO:0019220 349 0.017
regulation of nervous system development GO:0051960 264 0.017
regulation of signal transduction GO:0009966 318 0.017
heterocycle catabolic process GO:0046700 167 0.017
positive regulation of cell communication GO:0010647 271 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
ribonucleoside catabolic process GO:0042454 126 0.017
tissue development GO:0009888 252 0.017
regulation of protein phosphorylation GO:0001932 183 0.017
positive regulation of neuron differentiation GO:0045666 126 0.016
organ morphogenesis GO:0009887 75 0.016
cell cycle GO:0007049 101 0.016
regulation of map kinase activity GO:0043405 53 0.016
carboxylic acid metabolic process GO:0019752 289 0.016
negative regulation of catalytic activity GO:0043086 103 0.016
rna catabolic process GO:0006401 3 0.016
developmental growth GO:0048589 100 0.016
regulation of synaptic transmission GO:0050804 141 0.015
purine containing compound metabolic process GO:0072521 253 0.015
ras protein signal transduction GO:0007265 29 0.015
actin filament based process GO:0030029 86 0.015
regulation of cellular amino acid metabolic process GO:0006521 2 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
regulation of phosphorylation GO:0042325 248 0.015
renal system development GO:0072001 67 0.015
regulation of cellular component organization GO:0051128 368 0.015
regulation of cell development GO:0060284 263 0.014
response to oxidative stress GO:0006979 186 0.014
chromosome segregation GO:0007059 2 0.014
salivary gland development GO:0007431 3 0.014
regulation of protein serine threonine kinase activity GO:0071900 64 0.014
multicellular organism reproduction GO:0032504 233 0.014
positive regulation of cell development GO:0010720 176 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
male gamete generation GO:0048232 99 0.014
cellular amine metabolic process GO:0044106 38 0.014
sex differentiation GO:0007548 113 0.014
regulation of cellular amine metabolic process GO:0033238 8 0.013
palate development GO:0060021 2 0.013
programmed cell death GO:0012501 392 0.013
cyclic nucleotide metabolic process GO:0009187 80 0.013
mesoderm development GO:0007498 2 0.013
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.013
positive regulation of protein modification process GO:0031401 142 0.013
positive regulation of signal transduction GO:0009967 175 0.013
negative regulation of cell communication GO:0010648 158 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
single organism reproductive process GO:0044702 297 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
negative regulation of metabolic process GO:0009892 331 0.013
regulation of bmp signaling pathway GO:0030510 2 0.013
toxin transport GO:1901998 3 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
regulation of protein metabolic process GO:0051246 289 0.012
negative regulation of cellular metabolic process GO:0031324 281 0.012
brain development GO:0007420 247 0.012
single organism catabolic process GO:0044712 283 0.012
morphogenesis of an epithelium GO:0002009 20 0.012
purine ribonucleotide metabolic process GO:0009150 227 0.012
ribonucleotide biosynthetic process GO:0009260 85 0.012
sensory organ development GO:0007423 74 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
secretion GO:0046903 307 0.012
embryonic pattern specification GO:0009880 1 0.012
sexual reproduction GO:0019953 148 0.012
synaptic transmission GO:0007268 235 0.012
mechanoreceptor differentiation GO:0042490 2 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
cellular response to hormone stimulus GO:0032870 247 0.012
gamete generation GO:0007276 124 0.012
heart morphogenesis GO:0003007 3 0.012
multicellular organismal reproductive process GO:0048609 233 0.012
nucleotide biosynthetic process GO:0009165 98 0.011
epiboly involved in wound healing GO:0090505 2 0.011
positive regulation of multicellular organismal process GO:0051240 387 0.011
cyclic purine nucleotide metabolic process GO:0052652 62 0.011
skeletal system development GO:0001501 41 0.011
positive regulation of gene expression GO:0010628 244 0.011
multicellular organism growth GO:0035264 1 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
regulation of growth GO:0040008 105 0.011
positive regulation of catabolic process GO:0009896 78 0.011
purine ribonucleotide biosynthetic process GO:0009152 81 0.011
hair cell differentiation GO:0035315 2 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
reproductive system development GO:0061458 128 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.011
protein deubiquitination GO:0016579 4 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
negative regulation of signal transduction GO:0009968 83 0.010
regulation of rna stability GO:0043487 3 0.010
single organism biosynthetic process GO:0044711 342 0.010
cellular macromolecule catabolic process GO:0044265 29 0.010
development of primary sexual characteristics GO:0045137 107 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
purine nucleotide catabolic process GO:0006195 136 0.010

Helz disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
cardiovascular system disease DOID:1287 0 0.014
sensory system disease DOID:0050155 0 0.013
nervous system disease DOID:863 0 0.013