Rattus norvegicus

67 known processes

Numb

numb homolog (Drosophila)

(Aliases: MGC188364)

Numb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular component organization GO:0051128 368 0.111
regulation of rna biosynthetic process GO:2001141 381 0.056
protein complex subunit organization GO:0071822 302 0.053
intracellular signal transduction GO:0035556 314 0.052
regulation of molecular function GO:0065009 398 0.052
rna metabolic process GO:0016070 406 0.050
cellular component assembly GO:0022607 360 0.048
regulation of neurogenesis GO:0050767 247 0.047
nucleic acid templated transcription GO:0097659 379 0.047
cell cell signaling GO:0007267 335 0.046
secretion GO:0046903 307 0.045
regulation of signal transduction GO:0009966 318 0.044
regulation of transcription dna templated GO:0006355 374 0.044
cellular amino acid metabolic process GO:0006520 107 0.043
regulation of rna metabolic process GO:0051252 391 0.043
organelle organization GO:0006996 266 0.042
carboxylic acid metabolic process GO:0019752 289 0.042
transcription dna templated GO:0006351 377 0.042
rna biosynthetic process GO:0032774 380 0.040
regulation of nucleic acid templated transcription GO:1903506 380 0.039
catabolic process GO:0009056 351 0.039
cellular component biogenesis GO:0044085 368 0.038
oxoacid metabolic process GO:0043436 290 0.036
transmembrane transport GO:0055085 412 0.036
nucleobase containing small molecule metabolic process GO:0055086 316 0.035
vesicle mediated transport GO:0016192 181 0.035
programmed cell death GO:0012501 392 0.035
negative regulation of macromolecule metabolic process GO:0010605 260 0.034
negative regulation of cellular metabolic process GO:0031324 281 0.034
ras protein signal transduction GO:0007265 29 0.034
regulation of intracellular signal transduction GO:1902531 218 0.033
negative regulation of biosynthetic process GO:0009890 168 0.033
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.032
cellular response to oxygen containing compound GO:1901701 386 0.032
regulation of cell differentiation GO:0045595 320 0.032
regulation of phosphate metabolic process GO:0019220 349 0.032
organic substance catabolic process GO:1901575 316 0.032
cellular response to stress GO:0033554 269 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.031
cellular catabolic process GO:0044248 295 0.031
monovalent inorganic cation transport GO:0015672 172 0.031
regulation of multicellular organismal development GO:2000026 376 0.030
cellular amine metabolic process GO:0044106 38 0.030
positive regulation of response to stimulus GO:0048584 285 0.030
regulation of cell development GO:0060284 263 0.030
apoptotic process GO:0006915 381 0.029
single organism catabolic process GO:0044712 283 0.029
cation transport GO:0006812 382 0.029
positive regulation of phosphate metabolic process GO:0045937 262 0.029
ion transmembrane transport GO:0034220 365 0.029
amine metabolic process GO:0009308 38 0.029
protein complex assembly GO:0006461 263 0.029
carbohydrate derivative metabolic process GO:1901135 346 0.029
negative regulation of cellular biosynthetic process GO:0031327 161 0.028
macromolecular complex subunit organization GO:0043933 339 0.028
positive regulation of phosphorus metabolic process GO:0010562 262 0.028
protein complex biogenesis GO:0070271 263 0.028
organic acid metabolic process GO:0006082 292 0.028
response to nutrient levels GO:0031667 370 0.028
neuron differentiation GO:0030182 368 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.027
regulation of cellular ketone metabolic process GO:0010565 27 0.027
protein autophosphorylation GO:0046777 66 0.027
purine ribonucleotide metabolic process GO:0009150 227 0.027
positive regulation of multicellular organismal process GO:0051240 387 0.027
regulation of cellular amine metabolic process GO:0033238 8 0.026
central nervous system development GO:0007417 311 0.026
cellular ketone metabolic process GO:0042180 51 0.026
negative regulation of multicellular organismal process GO:0051241 203 0.026
regulation of neuron differentiation GO:0045664 208 0.026
positive regulation of nucleic acid templated transcription GO:1903508 197 0.025
macromolecular complex assembly GO:0065003 273 0.025
regulation of phosphorus metabolic process GO:0051174 349 0.025
cell projection organization GO:0030030 302 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.025
regulation of system process GO:0044057 208 0.025
positive regulation of molecular function GO:0044093 230 0.024
nitrogen compound transport GO:0071705 229 0.024
defense response GO:0006952 194 0.024
regulation of response to stress GO:0080134 126 0.024
regulation of proteasomal protein catabolic process GO:0061136 4 0.024
ribonucleoside metabolic process GO:0009119 174 0.024
positive regulation of gene expression GO:0010628 244 0.023
regulation of nervous system development GO:0051960 264 0.023
synaptic transmission GO:0007268 235 0.023
metal ion transport GO:0030001 289 0.023
cell part morphogenesis GO:0032990 123 0.023
positive regulation of biosynthetic process GO:0009891 319 0.023
nucleotide metabolic process GO:0009117 279 0.023
neuron development GO:0048666 286 0.023
protein phosphorylation GO:0006468 345 0.023
head development GO:0060322 247 0.022
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
regulation of protein modification process GO:0031399 194 0.022
dna integrity checkpoint GO:0031570 2 0.022
positive regulation of cellular biosynthetic process GO:0031328 295 0.022
negative regulation of gene expression GO:0010629 199 0.022
response to extracellular stimulus GO:0009991 380 0.022
regulation of phosphorylation GO:0042325 248 0.021
organic cyclic compound catabolic process GO:1901361 175 0.021
positive regulation of cellular component organization GO:0051130 200 0.021
nucleoside metabolic process GO:0009116 179 0.021
regulation of apoptotic process GO:0042981 335 0.021
anatomical structure morphogenesis GO:0009653 298 0.020
signal release GO:0023061 145 0.020
protein oligomerization GO:0051259 191 0.020
small gtpase mediated signal transduction GO:0007264 36 0.020
regulation of catalytic activity GO:0050790 304 0.020
positive regulation of transcription dna templated GO:0045893 197 0.020
positive regulation of transport GO:0051050 245 0.020
purine nucleotide metabolic process GO:0006163 229 0.020
organophosphate metabolic process GO:0019637 370 0.020
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.020
organonitrogen compound catabolic process GO:1901565 179 0.020
cation transmembrane transport GO:0098655 263 0.020
secretion by cell GO:0032940 248 0.020
macromolecule localization GO:0033036 252 0.020
cell morphogenesis GO:0000902 142 0.020
response to cytokine GO:0034097 215 0.020
positive regulation of cell differentiation GO:0045597 217 0.020
glycosyl compound metabolic process GO:1901657 182 0.020
ribonucleotide metabolic process GO:0009259 231 0.020
regulation of programmed cell death GO:0043067 341 0.019
reproductive process GO:0022414 372 0.019
protein localization GO:0008104 191 0.019
regulation of protein metabolic process GO:0051246 289 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
neuron projection development GO:0031175 273 0.019
dna metabolic process GO:0006259 96 0.019
cell cycle checkpoint GO:0000075 2 0.019
purine containing compound metabolic process GO:0072521 253 0.019
negative regulation of metabolic process GO:0009892 331 0.019
regulation of ion transmembrane transport GO:0034765 121 0.019
cellular response to nitrogen compound GO:1901699 210 0.019
ribose phosphate metabolic process GO:0019693 235 0.019
brain development GO:0007420 247 0.018
positive regulation of developmental process GO:0051094 283 0.018
regulation of cellular protein metabolic process GO:0032268 267 0.018
transcription from rna polymerase ii promoter GO:0006366 252 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
lipid metabolic process GO:0006629 283 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.018
ribonucleoside triphosphate metabolic process GO:0009199 141 0.018
positive regulation of neurogenesis GO:0050769 165 0.018
multi organism reproductive process GO:0044703 262 0.018
inorganic cation transmembrane transport GO:0098662 202 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.018
regulation of membrane potential GO:0042391 110 0.017
heart morphogenesis GO:0003007 3 0.017
nucleobase containing compound catabolic process GO:0034655 152 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
cell morphogenesis involved in differentiation GO:0000904 119 0.017
protein heterooligomerization GO:0051291 89 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
membrane organization GO:0061024 94 0.017
regulation of ion transport GO:0043269 245 0.017
regulation of protein phosphorylation GO:0001932 183 0.017
synaptic growth at neuromuscular junction GO:0051124 1 0.017
heterocycle catabolic process GO:0046700 167 0.017
immune response GO:0006955 104 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
aromatic compound catabolic process GO:0019439 168 0.016
endocytosis GO:0006897 84 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
proteolysis GO:0006508 175 0.016
response to oxidative stress GO:0006979 186 0.016
reproduction GO:0000003 245 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
positive regulation of rna metabolic process GO:0051254 203 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.016
response to growth factor GO:0070848 189 0.015
purine nucleoside triphosphate metabolic process GO:0009144 141 0.015
positive regulation of nervous system development GO:0051962 178 0.015
positive regulation of signal transduction GO:0009967 175 0.015
aging GO:0007568 241 0.015
action potential GO:0001508 54 0.015
nucleoside phosphate metabolic process GO:0006753 283 0.015
steroid metabolic process GO:0008202 73 0.015
negative regulation of developmental process GO:0051093 125 0.015
response to oxygen levels GO:0070482 265 0.015
homeostatic process GO:0042592 331 0.015
nucleoside catabolic process GO:0009164 126 0.015
regulation of metal ion transport GO:0010959 118 0.015
regulation of catabolic process GO:0009894 113 0.015
cell type specific apoptotic process GO:0097285 134 0.015
chemical homeostasis GO:0048878 292 0.015
regulation of cell projection organization GO:0031344 175 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.015
muscle system process GO:0003012 115 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
regulation of hormone levels GO:0010817 187 0.014
cell projection morphogenesis GO:0048858 123 0.014
anion transport GO:0006820 178 0.014
positive regulation of cell development GO:0010720 176 0.014
regulation of cell proliferation GO:0042127 359 0.014
response to peptide hormone GO:0043434 278 0.014
cellular response to endogenous stimulus GO:0071495 377 0.014
regulation of neuron projection development GO:0010975 161 0.014
positive regulation of cell communication GO:0010647 271 0.014
single organism reproductive process GO:0044702 297 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
response to peptide GO:1901652 292 0.014
negative regulation of cellular component organization GO:0051129 83 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.014
axis specification GO:0009798 4 0.014
purine ribonucleoside metabolic process GO:0046128 168 0.014
single organism organelle organization GO:1902589 180 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
positive regulation of signaling GO:0023056 270 0.014
negative regulation of rna metabolic process GO:0051253 123 0.014
cellular macromolecule localization GO:0070727 122 0.014
intracellular transport GO:0046907 185 0.014
eye morphogenesis GO:0048592 4 0.014
immune system process GO:0002376 204 0.014
positive regulation of protein metabolic process GO:0051247 178 0.013
organelle localization GO:0051640 55 0.013
regulation of transmembrane transport GO:0034762 122 0.013
circulatory system process GO:0003013 183 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.013
response to glucose GO:0009749 136 0.013
cellular response to external stimulus GO:0071496 118 0.013
response to ethanol GO:0045471 162 0.013
multicellular organism reproduction GO:0032504 233 0.013
oxidation reduction process GO:0055114 304 0.013
embryonic pattern specification GO:0009880 1 0.013
multicellular organismal reproductive process GO:0048609 233 0.013
neuron death GO:0070997 127 0.013
negative regulation of cell death GO:0060548 229 0.013
response to insulin GO:0032868 133 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
anterior posterior pattern specification GO:0009952 1 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.013
purine ribonucleoside catabolic process GO:0046130 124 0.013
response to hypoxia GO:0001666 231 0.012
negative regulation of cell communication GO:0010648 158 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
regulation of secretion by cell GO:1903530 208 0.012
response to inorganic substance GO:0010035 377 0.012
blood circulation GO:0008015 183 0.012
establishment of organelle localization GO:0051656 37 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
multicellular organismal signaling GO:0035637 44 0.012
neurological system process GO:0050877 219 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
guanosine containing compound metabolic process GO:1901068 74 0.012
cellular homeostasis GO:0019725 252 0.012
response to nutrient GO:0007584 248 0.012
circadian rhythm GO:0007623 88 0.012
regulation of ion transmembrane transporter activity GO:0032412 48 0.012
response to external biotic stimulus GO:0043207 221 0.012
signal transduction by phosphorylation GO:0023014 144 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
regulation of cell cycle GO:0051726 73 0.012
regulation of secretion GO:0051046 224 0.012
single organism intracellular transport GO:1902582 166 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.011
adult locomotory behavior GO:0008344 4 0.011
cellular lipid metabolic process GO:0044255 208 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
response to corticosteroid GO:0031960 235 0.011
cellular component morphogenesis GO:0032989 155 0.011
regeneration GO:0031099 163 0.011
response to biotic stimulus GO:0009607 226 0.011
growth GO:0040007 165 0.011
positive regulation of protein modification process GO:0031401 142 0.011
regulation of hydrolase activity GO:0051336 143 0.011
rhythmic process GO:0048511 156 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.011
multicellular organism growth GO:0035264 1 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
response to ketone GO:1901654 182 0.011
response to decreased oxygen levels GO:0036293 237 0.011
rho protein signal transduction GO:0007266 11 0.011
cellular response to peptide GO:1901653 133 0.011
alcohol metabolic process GO:0006066 77 0.011
regulation of neuron death GO:1901214 115 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
cellular component movement GO:0006928 248 0.011
sex differentiation GO:0007548 113 0.011
negative regulation of cell development GO:0010721 82 0.011
regulation of muscle system process GO:0090257 79 0.011
regulation of organelle organization GO:0033043 80 0.011
negative regulation of nucleic acid templated transcription GO:1903507 117 0.011
rna localization GO:0006403 4 0.011
positive regulation of catabolic process GO:0009896 78 0.011
response to glucocorticoid GO:0051384 223 0.011
cellular chemical homeostasis GO:0055082 247 0.011
chromosome segregation GO:0007059 2 0.011
response to acid chemical GO:0001101 222 0.011
organophosphate catabolic process GO:0046434 148 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
regulation of gtpase activity GO:0043087 57 0.010
cytoplasmic transport GO:0016482 115 0.010
organic hydroxy compound metabolic process GO:1901615 115 0.010
negative regulation of transport GO:0051051 136 0.010
cellular response to extracellular stimulus GO:0031668 73 0.010
cellular protein localization GO:0034613 122 0.010
amide transport GO:0042886 105 0.010
neuron projection morphogenesis GO:0048812 122 0.010
carbohydrate derivative catabolic process GO:1901136 147 0.010
reproductive structure development GO:0048608 128 0.010
positive regulation of nucleotide metabolic process GO:0045981 91 0.010
negative regulation of molecular function GO:0044092 133 0.010
nucleoside phosphate catabolic process GO:1901292 140 0.010
regulation of protein kinase activity GO:0045859 105 0.010
mapk cascade GO:0000165 140 0.010
cardiac chamber development GO:0003205 1 0.010
positive regulation of gtp catabolic process GO:0033126 48 0.010
regulation of purine nucleotide catabolic process GO:0033121 65 0.010

Numb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.014
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.013
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.012
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012