Rattus norvegicus

0 known processes

Entpd2

ectonucleoside triphosphate diphosphohydrolase 2

(Aliases: Cd39l1,NTPDase2)

Entpd2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid metabolic process GO:0019752 289 0.231
oxoacid metabolic process GO:0043436 290 0.179
organic acid metabolic process GO:0006082 292 0.159
lipid metabolic process GO:0006629 283 0.122
catabolic process GO:0009056 351 0.122
Mouse
cellular response to endogenous stimulus GO:0071495 377 0.112
apoptotic process GO:0006915 381 0.101
response to metal ion GO:0010038 253 0.087
Zebrafish
organophosphate metabolic process GO:0019637 370 0.087
Mouse
single organism biosynthetic process GO:0044711 342 0.084
cellular amino acid metabolic process GO:0006520 107 0.081
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.080
reproductive process GO:0022414 372 0.077
regulation of multicellular organismal development GO:2000026 376 0.076
cell cell signaling GO:0007267 335 0.072
organic substance catabolic process GO:1901575 316 0.066
Mouse
single organism reproductive process GO:0044702 297 0.065
multi organism reproductive process GO:0044703 262 0.063
monocarboxylic acid metabolic process GO:0032787 152 0.063
response to inorganic substance GO:0010035 377 0.061
Zebrafish
cellular catabolic process GO:0044248 295 0.060
Mouse
cellular component biogenesis GO:0044085 368 0.060
regulation of apoptotic process GO:0042981 335 0.059
regulation of secretion GO:0051046 224 0.058
cellular response to hormone stimulus GO:0032870 247 0.056
response to peptide GO:1901652 292 0.056
regulation of phosphorus metabolic process GO:0051174 349 0.055
positive regulation of multicellular organismal process GO:0051240 387 0.052
macromolecular complex assembly GO:0065003 273 0.052
programmed cell death GO:0012501 392 0.052
cell projection organization GO:0030030 302 0.051
oxidation reduction process GO:0055114 304 0.051
aging GO:0007568 241 0.050
cellular response to oxygen containing compound GO:1901701 386 0.050
Zebrafish
positive regulation of signaling GO:0023056 270 0.049
regulation of cellular component organization GO:0051128 368 0.049
regulation of molecular function GO:0065009 398 0.049
response to peptide hormone GO:0043434 278 0.049
multicellular organism reproduction GO:0032504 233 0.048
regulation of cellular amine metabolic process GO:0033238 8 0.048
regulation of nervous system development GO:0051960 264 0.048
regulation of protein metabolic process GO:0051246 289 0.048
cellular component assembly GO:0022607 360 0.048
amine metabolic process GO:0009308 38 0.048
ribonucleotide metabolic process GO:0009259 231 0.047
protein complex subunit organization GO:0071822 302 0.047
cellular response to stress GO:0033554 269 0.047
regulation of cell differentiation GO:0045595 320 0.046
intracellular signal transduction GO:0035556 314 0.046
response to glucocorticoid GO:0051384 223 0.045
monovalent inorganic cation transport GO:0015672 172 0.044
reproduction GO:0000003 245 0.044
cellular amine metabolic process GO:0044106 38 0.043
locomotion GO:0040011 237 0.042
cation transport GO:0006812 382 0.041
response to oxygen levels GO:0070482 265 0.041
regulation of cellular ketone metabolic process GO:0010565 27 0.040
macromolecular complex subunit organization GO:0043933 339 0.040
regulation of hormone levels GO:0010817 187 0.040
secretion GO:0046903 307 0.040
cellular lipid metabolic process GO:0044255 208 0.040
female pregnancy GO:0007565 122 0.039
protein phosphorylation GO:0006468 345 0.039
single organism catabolic process GO:0044712 283 0.039
Mouse
regulation of ion transport GO:0043269 245 0.039
cellular ketone metabolic process GO:0042180 51 0.039
carbohydrate derivative metabolic process GO:1901135 346 0.039
response to estradiol GO:0032355 164 0.039
multi multicellular organism process GO:0044706 138 0.039
cell migration GO:0016477 197 0.038
purine containing compound metabolic process GO:0072521 253 0.038
response to extracellular stimulus GO:0009991 380 0.038
regulation of programmed cell death GO:0043067 341 0.038
synaptic transmission GO:0007268 235 0.037
response to corticosteroid GO:0031960 235 0.037
regulation of phosphorylation GO:0042325 248 0.036
metal ion transport GO:0030001 289 0.036
neuron projection development GO:0031175 273 0.036
regulation of neuron differentiation GO:0045664 208 0.035
regulation of cellular amino acid metabolic process GO:0006521 2 0.035
homeostatic process GO:0042592 331 0.035
negative regulation of metabolic process GO:0009892 331 0.034
response to biotic stimulus GO:0009607 226 0.034
multicellular organismal reproductive process GO:0048609 233 0.034
head development GO:0060322 247 0.034
positive regulation of phosphate metabolic process GO:0045937 262 0.034
transcription dna templated GO:0006351 377 0.033
regulation of cellular localization GO:0060341 263 0.033
response to monosaccharide GO:0034284 159 0.033
positive regulation of cell communication GO:0010647 271 0.033
rna metabolic process GO:0016070 406 0.033
organonitrogen compound biosynthetic process GO:1901566 167 0.033
cellular response to nitrogen compound GO:1901699 210 0.033
regeneration GO:0031099 163 0.033
regulation of cell proliferation GO:0042127 359 0.032
cellular response to organonitrogen compound GO:0071417 197 0.032
response to hexose GO:0009746 144 0.032
positive regulation of transport GO:0051050 245 0.032
central nervous system development GO:0007417 311 0.032
negative regulation of apoptotic process GO:0043066 181 0.031
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.031
regulation of phosphate metabolic process GO:0019220 349 0.030
nucleobase containing small molecule metabolic process GO:0055086 316 0.030
Mouse
nucleoside phosphate metabolic process GO:0006753 283 0.030
Mouse
response to cytokine GO:0034097 215 0.030
negative regulation of programmed cell death GO:0043069 183 0.030
neuron development GO:0048666 286 0.029
protein complex assembly GO:0006461 263 0.029
response to carbohydrate GO:0009743 183 0.029
ribose phosphate metabolic process GO:0019693 235 0.029
negative regulation of cell death GO:0060548 229 0.029
anatomical structure morphogenesis GO:0009653 298 0.029
cellular component movement GO:0006928 248 0.029
regulation of cellular protein metabolic process GO:0032268 267 0.028
nucleoside metabolic process GO:0009116 179 0.028
positive regulation of response to stimulus GO:0048584 285 0.028
regulation of metal ion transport GO:0010959 118 0.028
rna biosynthetic process GO:0032774 380 0.028
amide transport GO:0042886 105 0.028
regulation of intracellular signal transduction GO:1902531 218 0.028
nucleotide metabolic process GO:0009117 279 0.028
g protein coupled receptor signaling pathway GO:0007186 242 0.027
Mouse
carboxylic acid biosynthetic process GO:0046394 83 0.027
secretion by cell GO:0032940 248 0.027
localization of cell GO:0051674 202 0.027
proteolysis GO:0006508 175 0.027
cell motility GO:0048870 202 0.027
positive regulation of cellular protein metabolic process GO:0032270 167 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
neuron death GO:0070997 127 0.027
organelle organization GO:0006996 266 0.026
response to glucose GO:0009749 136 0.026
peptidyl amino acid modification GO:0018193 126 0.026
protein complex biogenesis GO:0070271 263 0.026
response to oxidative stress GO:0006979 186 0.026
regulation of protein modification process GO:0031399 194 0.025
fatty acid metabolic process GO:0006631 99 0.025
response to decreased oxygen levels GO:0036293 237 0.024
transmembrane transport GO:0055085 412 0.024
positive regulation of cellular amine metabolic process GO:0033240 3 0.024
positive regulation of protein metabolic process GO:0051247 178 0.024
regulation of secretion by cell GO:1903530 208 0.024
positive regulation of developmental process GO:0051094 283 0.024
regulation of neuron projection development GO:0010975 161 0.023
nucleic acid templated transcription GO:0097659 379 0.023
neuron differentiation GO:0030182 368 0.023
purine ribonucleotide metabolic process GO:0009150 227 0.023
response to ethanol GO:0045471 162 0.023
Zebrafish
cellular homeostasis GO:0019725 252 0.023
regulation of hormone secretion GO:0046883 106 0.023
regulation of neurogenesis GO:0050767 247 0.023
nitrogen compound transport GO:0071705 229 0.023
divalent inorganic cation transport GO:0072511 134 0.022
response to organophosphorus GO:0046683 102 0.022
regulation of peptide hormone secretion GO:0090276 80 0.022
vesicle mediated transport GO:0016192 181 0.022
response to other organism GO:0051707 220 0.022
response to hypoxia GO:0001666 231 0.022
organic acid biosynthetic process GO:0016053 83 0.022
positive regulation of cell proliferation GO:0008284 249 0.022
response to molecule of bacterial origin GO:0002237 194 0.022
negative regulation of response to stimulus GO:0048585 155 0.021
response to growth factor GO:0070848 189 0.021
signal release GO:0023061 145 0.021
positive regulation of cell motility GO:2000147 97 0.021
regulation of cell development GO:0060284 263 0.021
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.021
ion transmembrane transport GO:0034220 365 0.021
regulation of peptide transport GO:0090087 87 0.021
negative regulation of cell differentiation GO:0045596 99 0.021
positive regulation of cell differentiation GO:0045597 217 0.021
regulation of catalytic activity GO:0050790 304 0.021
lipid biosynthetic process GO:0008610 128 0.021
regulation of rna metabolic process GO:0051252 391 0.021
purine nucleotide metabolic process GO:0006163 229 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.021
negative regulation of cellular metabolic process GO:0031324 281 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
organophosphate biosynthetic process GO:0090407 143 0.020
chemical homeostasis GO:0048878 292 0.020
response to radiation GO:0009314 137 0.020
response to nutrient levels GO:0031667 370 0.020
cell adhesion GO:0007155 110 0.020
regulation of signal transduction GO:0009966 318 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
response to insulin GO:0032868 133 0.020
positive regulation of phosphorus metabolic process GO:0010562 262 0.020
blood circulation GO:0008015 183 0.020
negative regulation of signaling GO:0023057 157 0.020
regulation of peptide secretion GO:0002791 82 0.020
glycosyl compound metabolic process GO:1901657 182 0.019
hormone transport GO:0009914 121 0.019
cyclic nucleotide metabolic process GO:0009187 80 0.019
tissue development GO:0009888 252 0.019
regulation of membrane potential GO:0042391 110 0.019
cellular response to peptide hormone stimulus GO:0071375 120 0.019
response to acid chemical GO:0001101 222 0.019
Zebrafish
regulation of anatomical structure size GO:0090066 135 0.019
response to wounding GO:0009611 254 0.019
Mouse
regulation of nucleic acid templated transcription GO:1903506 380 0.019
small gtpase mediated signal transduction GO:0007264 36 0.018
response to ketone GO:1901654 182 0.018
transcription from rna polymerase ii promoter GO:0006366 252 0.018
cellular chemical homeostasis GO:0055082 247 0.018
behavior GO:0007610 205 0.018
organic hydroxy compound metabolic process GO:1901615 115 0.018
regulation of cell migration GO:0030334 128 0.018
protein localization GO:0008104 191 0.018
small molecule biosynthetic process GO:0044283 124 0.018
macromolecule localization GO:0033036 252 0.018
cellular response to external stimulus GO:0071496 118 0.018
growth GO:0040007 165 0.018
response to estrogen GO:0043627 232 0.018
anion transport GO:0006820 178 0.018
response to nutrient GO:0007584 248 0.018
regulation of transcription dna templated GO:0006355 374 0.017
rhythmic process GO:0048511 156 0.017
cellular response to peptide GO:1901653 133 0.017
regulation of synaptic transmission GO:0050804 141 0.017
cation homeostasis GO:0055080 195 0.017
regulation of rna biosynthetic process GO:2001141 381 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.017
hormone secretion GO:0046879 115 0.017
response to hydrogen peroxide GO:0042542 89 0.017
single organism organelle organization GO:1902589 180 0.017
neurological system process GO:0050877 219 0.017
regulation of locomotion GO:0040012 148 0.017
peptide secretion GO:0002790 86 0.017
alpha amino acid metabolic process GO:1901605 71 0.017
enzyme linked receptor protein signaling pathway GO:0007167 116 0.016
response to lipopolysaccharide GO:0032496 191 0.016
cell type specific apoptotic process GO:0097285 134 0.016
actin cytoskeleton organization GO:0030036 73 0.016
response to external biotic stimulus GO:0043207 221 0.016
muscle structure development GO:0061061 87 0.016
muscle contraction GO:0006936 88 0.016
cation transmembrane transport GO:0098655 263 0.016
positive regulation of nervous system development GO:0051962 178 0.016
mapk cascade GO:0000165 140 0.016
peptide transport GO:0015833 97 0.016
positive regulation of protein modification process GO:0031401 142 0.016
response to camp GO:0051591 91 0.016
regulation of catabolic process GO:0009894 113 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
positive regulation of cell development GO:0010720 176 0.016
ras protein signal transduction GO:0007265 29 0.015
cardiovascular system development GO:0072358 134 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.015
circulatory system process GO:0003013 183 0.015
brain development GO:0007420 247 0.015
gamete generation GO:0007276 124 0.015
actin filament based process GO:0030029 86 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
Mouse
cellular response to vitamin e GO:0071306 3 0.015
regulation of cell projection organization GO:0031344 175 0.015
heterocycle catabolic process GO:0046700 167 0.015
Mouse
regulation of cell motility GO:2000145 131 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
positive regulation of secretion by cell GO:1903532 128 0.015
response to purine containing compound GO:0014074 126 0.015
cellular response to extracellular stimulus GO:0031668 73 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
neuronal action potential GO:0019228 35 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.015
single organism behavior GO:0044708 130 0.014
ion homeostasis GO:0050801 212 0.014
calcium ion transport GO:0006816 131 0.014
negative regulation of developmental process GO:0051093 125 0.014
negative regulation of cell proliferation GO:0008285 119 0.014
regulation of anatomical structure morphogenesis GO:0022603 141 0.014
glycerolipid metabolic process GO:0046486 67 0.014
regulation of cellular component movement GO:0051270 150 0.014
regulation of system process GO:0044057 208 0.014
positive regulation of programmed cell death GO:0043068 157 0.014
cell morphogenesis GO:0000902 142 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
defense response GO:0006952 194 0.014
response to calcium ion GO:0051592 59 0.014
hormone metabolic process GO:0042445 69 0.014
positive regulation of biosynthetic process GO:0009891 319 0.014
positive regulation of cell projection organization GO:0031346 111 0.014
gliogenesis GO:0042063 93 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
negative regulation of cellular component organization GO:0051129 83 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
divalent metal ion transport GO:0070838 132 0.014
myelination GO:0042552 39 0.014
positive regulation of catalytic activity GO:0043085 184 0.014
isoprenoid metabolic process GO:0006720 45 0.014
response to hyperoxia GO:0055093 45 0.014
intracellular transport GO:0046907 185 0.014
organic anion transport GO:0015711 132 0.014
response to increased oxygen levels GO:0036296 45 0.013
positive regulation of cellular component movement GO:0051272 102 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.013
cellular ion homeostasis GO:0006873 184 0.013
cellular response to insulin stimulus GO:0032869 81 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
positive regulation of peptide hormone secretion GO:0090277 50 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
ribose phosphate biosynthetic process GO:0046390 87 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
sexual reproduction GO:0019953 148 0.013
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.013
peptidyl tyrosine phosphorylation GO:0018108 72 0.013
protein oligomerization GO:0051259 191 0.013
sodium ion transport GO:0006814 82 0.013
purine nucleoside triphosphate metabolic process GO:0009144 141 0.013
respiratory system development GO:0060541 45 0.013
gland development GO:0048732 155 0.013
purine containing compound biosynthetic process GO:0072522 85 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
positive regulation of transcription dna templated GO:0045893 197 0.012
cytoskeleton organization GO:0007010 111 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
regulation of cell growth GO:0001558 85 0.012
insulin secretion GO:0030073 69 0.012
forebrain development GO:0030900 98 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
Mouse
regulation of insulin secretion GO:0050796 65 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
Mouse
reactive oxygen species metabolic process GO:0072593 37 0.012
inflammatory response GO:0006954 150 0.012
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.012
developmental process involved in reproduction GO:0003006 159 0.012
metal ion homeostasis GO:0055065 186 0.012
circadian rhythm GO:0007623 88 0.012
glial cell differentiation GO:0010001 65 0.012
regulation of calcium ion transport GO:0051924 77 0.012
cellular response to cytokine stimulus GO:0071345 127 0.012
carboxylic acid transport GO:0046942 115 0.012
positive regulation of gene expression GO:0010628 244 0.012
nucleotide catabolic process GO:0009166 139 0.012
response to alkaloid GO:0043279 132 0.012
positive regulation of apoptotic process GO:0043065 154 0.012
regulation of response to stress GO:0080134 126 0.012
organophosphate catabolic process GO:0046434 148 0.012
Mouse
response to bacterium GO:0009617 200 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
negative regulation of transport GO:0051051 136 0.012
positive regulation of signal transduction GO:0009967 175 0.012
regulation of cell adhesion GO:0030155 52 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
aromatic compound catabolic process GO:0019439 168 0.011
Mouse
muscle system process GO:0003012 115 0.011
regulation of transferase activity GO:0051338 123 0.011
cellular cation homeostasis GO:0030003 180 0.011
endocytosis GO:0006897 84 0.011
glucose homeostasis GO:0042593 75 0.011
vascular process in circulatory system GO:0003018 96 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
positive regulation of cell death GO:0010942 184 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
Mouse
negative regulation of molecular function GO:0044092 133 0.011
cognition GO:0050890 92 0.011
negative regulation of cell communication GO:0010648 158 0.011
circulatory system development GO:0072359 134 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
camp metabolic process GO:0046058 63 0.011
calcium ion homeostasis GO:0055074 162 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
response to toxic substance GO:0009636 133 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
negative regulation of neuron differentiation GO:0045665 62 0.011
positive regulation of hormone secretion GO:0046887 65 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
hepaticobiliary system development GO:0061008 90 0.011
axis specification GO:0009798 4 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.010
peptide hormone secretion GO:0030072 84 0.010
potassium ion transport GO:0006813 97 0.010
regulation of growth GO:0040008 105 0.010
male gamete generation GO:0048232 99 0.010
glycosyl compound catabolic process GO:1901658 126 0.010
ribonucleoside triphosphate metabolic process GO:0009199 141 0.010
carbohydrate biosynthetic process GO:0016051 42 0.010
carbohydrate derivative catabolic process GO:1901136 147 0.010
protein processing GO:0016485 68 0.010
reactive oxygen species biosynthetic process GO:1903409 8 0.010
organ morphogenesis GO:0009887 75 0.010
blood vessel development GO:0001568 69 0.010
biological adhesion GO:0022610 110 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
alcohol metabolic process GO:0006066 77 0.010
regulation of blood circulation GO:1903522 110 0.010
purine ribonucleoside metabolic process GO:0046128 168 0.010
regulation of vesicle mediated transport GO:0060627 81 0.010
negative regulation of gene expression GO:0010629 199 0.010
organ regeneration GO:0031100 101 0.010
multicellular organismal signaling GO:0035637 44 0.010

Entpd2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
nervous system disease DOID:863 0 0.033
musculoskeletal system disease DOID:17 0 0.031
disease of metabolism DOID:0014667 0 0.017
central nervous system disease DOID:331 0 0.014
inherited metabolic disorder DOID:655 0 0.012
amino acid metabolic disorder DOID:9252 0 0.011
sensory system disease DOID:0050155 0 0.010