Rattus norvegicus

0 known processes

Sarm1

sterile alpha and TIR motif containing 1

Sarm1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
intracellular signal transduction GO:0035556 314 0.113
positive regulation of multicellular organismal process GO:0051240 387 0.090
programmed cell death GO:0012501 392 0.074
regulation of signal transduction GO:0009966 318 0.062
positive regulation of signaling GO:0023056 270 0.060
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.060
catabolic process GO:0009056 351 0.059
carbohydrate derivative metabolic process GO:1901135 346 0.058
protein phosphorylation GO:0006468 345 0.054
regulation of secretion GO:0051046 224 0.050
nucleic acid templated transcription GO:0097659 379 0.046
cell cell signaling GO:0007267 335 0.045
positive regulation of response to stimulus GO:0048584 285 0.044
response to oxygen levels GO:0070482 265 0.043
positive regulation of phosphate metabolic process GO:0045937 262 0.042
regulation of phosphorylation GO:0042325 248 0.041
rna biosynthetic process GO:0032774 380 0.041
vesicle mediated transport GO:0016192 181 0.041
neuron differentiation GO:0030182 368 0.040
regulation of intracellular signal transduction GO:1902531 218 0.038
nitrogen compound transport GO:0071705 229 0.037
regulation of rna metabolic process GO:0051252 391 0.037
regulation of phosphorus metabolic process GO:0051174 349 0.037
ribonucleotide metabolic process GO:0009259 231 0.037
nucleoside phosphate metabolic process GO:0006753 283 0.037
cellular homeostasis GO:0019725 252 0.036
cellular component movement GO:0006928 248 0.036
regulation of molecular function GO:0065009 398 0.036
cellular ion homeostasis GO:0006873 184 0.035
localization of cell GO:0051674 202 0.035
regulation of system process GO:0044057 208 0.034
response to extracellular stimulus GO:0009991 380 0.034
cellular catabolic process GO:0044248 295 0.033
response to decreased oxygen levels GO:0036293 237 0.033
cation transport GO:0006812 382 0.032
organophosphate metabolic process GO:0019637 370 0.032
organic substance catabolic process GO:1901575 316 0.031
regulation of transcription dna templated GO:0006355 374 0.031
purine containing compound metabolic process GO:0072521 253 0.031
apoptotic process GO:0006915 381 0.031
cellular response to oxygen containing compound GO:1901701 386 0.031
regulation of phosphate metabolic process GO:0019220 349 0.031
nucleotide metabolic process GO:0009117 279 0.031
regulation of cellular localization GO:0060341 263 0.031
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.030
nucleobase containing small molecule metabolic process GO:0055086 316 0.030
regulation of cellular component organization GO:0051128 368 0.030
central nervous system development GO:0007417 311 0.030
hormone transport GO:0009914 121 0.030
neurological system process GO:0050877 219 0.030
regulation of purine nucleotide metabolic process GO:1900542 115 0.029
single organism catabolic process GO:0044712 283 0.029
organic acid metabolic process GO:0006082 292 0.029
regulation of nucleic acid templated transcription GO:1903506 380 0.028
positive regulation of cell communication GO:0010647 271 0.028
rna metabolic process GO:0016070 406 0.028
regulation of programmed cell death GO:0043067 341 0.028
glycosyl compound metabolic process GO:1901657 182 0.028
head development GO:0060322 247 0.027
positive regulation of cell proliferation GO:0008284 249 0.026
regulation of catalytic activity GO:0050790 304 0.026
macromolecular complex assembly GO:0065003 273 0.026
regulation of multicellular organismal development GO:2000026 376 0.025
aging GO:0007568 241 0.025
regulation of purine nucleotide catabolic process GO:0033121 65 0.025
regulation of protein phosphorylation GO:0001932 183 0.025
response to corticosteroid GO:0031960 235 0.024
regulation of neuron differentiation GO:0045664 208 0.024
tissue development GO:0009888 252 0.024
negative regulation of signaling GO:0023057 157 0.024
cellular chemical homeostasis GO:0055082 247 0.024
macromolecule localization GO:0033036 252 0.024
cellular component biogenesis GO:0044085 368 0.023
response to cytokine GO:0034097 215 0.023
negative regulation of cellular metabolic process GO:0031324 281 0.023
cellular response to hormone stimulus GO:0032870 247 0.023
regulation of apoptotic process GO:0042981 335 0.023
ribose phosphate metabolic process GO:0019693 235 0.023
forebrain development GO:0030900 98 0.023
behavior GO:0007610 205 0.023
ras protein signal transduction GO:0007265 29 0.023
ribonucleotide catabolic process GO:0009261 136 0.023
lipid metabolic process GO:0006629 283 0.023
neuron projection development GO:0031175 273 0.023
metal ion transport GO:0030001 289 0.023
anion transport GO:0006820 178 0.023
transcription dna templated GO:0006351 377 0.023
purine nucleotide metabolic process GO:0006163 229 0.023
regulation of anatomical structure morphogenesis GO:0022603 141 0.022
oxoacid metabolic process GO:0043436 290 0.022
locomotion GO:0040011 237 0.022
regulation of protein metabolic process GO:0051246 289 0.022
regulation of cellular ketone metabolic process GO:0010565 27 0.022
g protein coupled receptor signaling pathway GO:0007186 242 0.022
single organism intracellular transport GO:1902582 166 0.022
purine containing compound biosynthetic process GO:0072522 85 0.022
response to hypoxia GO:0001666 231 0.022
organonitrogen compound catabolic process GO:1901565 179 0.022
multicellular organismal reproductive process GO:0048609 233 0.022
intracellular transport GO:0046907 185 0.022
cell projection organization GO:0030030 302 0.022
small gtpase mediated signal transduction GO:0007264 36 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.021
regulation of proteasomal protein catabolic process GO:0061136 4 0.021
positive regulation of molecular function GO:0044093 230 0.021
regulation of secretion by cell GO:1903530 208 0.021
regulation of gtpase activity GO:0043087 57 0.021
regulation of nervous system development GO:0051960 264 0.021
regulation of hydrolase activity GO:0051336 143 0.020
response to external biotic stimulus GO:0043207 221 0.020
single organism reproductive process GO:0044702 297 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
positive regulation of cellular protein metabolic process GO:0032270 167 0.020
reproductive structure development GO:0048608 128 0.020
macromolecular complex subunit organization GO:0043933 339 0.020
multicellular organism reproduction GO:0032504 233 0.020
protein oligomerization GO:0051259 191 0.020
reproductive system development GO:0061458 128 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
purine ribonucleoside metabolic process GO:0046128 168 0.020
protein complex assembly GO:0006461 263 0.020
reproductive process GO:0022414 372 0.020
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.020
purine ribonucleotide catabolic process GO:0009154 136 0.020
regulation of cellular protein metabolic process GO:0032268 267 0.019
positive regulation of gene expression GO:0010628 244 0.019
divalent inorganic cation homeostasis GO:0072507 165 0.019
purine nucleoside metabolic process GO:0042278 169 0.019
rhythmic process GO:0048511 156 0.019
heterocycle catabolic process GO:0046700 167 0.019
proteolysis GO:0006508 175 0.019
carboxylic acid metabolic process GO:0019752 289 0.019
cellular amino acid metabolic process GO:0006520 107 0.019
hormone secretion GO:0046879 115 0.019
cellular amine metabolic process GO:0044106 38 0.019
response to inorganic substance GO:0010035 377 0.019
cellular response to abiotic stimulus GO:0071214 85 0.019
regulation of neurogenesis GO:0050767 247 0.019
response to nutrient levels GO:0031667 370 0.019
negative regulation of metabolic process GO:0009892 331 0.019
cellular response to stress GO:0033554 269 0.019
cognition GO:0050890 92 0.019
guanosine containing compound catabolic process GO:1901069 71 0.019
organ regeneration GO:0031100 101 0.019
regulation of rna biosynthetic process GO:2001141 381 0.018
positive regulation of nervous system development GO:0051962 178 0.018
single organism biosynthetic process GO:0044711 342 0.018
sex differentiation GO:0007548 113 0.018
response to molecule of bacterial origin GO:0002237 194 0.018
cell migration GO:0016477 197 0.018
regulation of cell proliferation GO:0042127 359 0.018
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.018
ion transmembrane transport GO:0034220 365 0.018
positive regulation of phosphorus metabolic process GO:0010562 262 0.018
positive regulation of biosynthetic process GO:0009891 319 0.018
positive regulation of nucleotide metabolic process GO:0045981 91 0.018
cytosolic calcium ion homeostasis GO:0051480 140 0.018
positive regulation of signal transduction GO:0009967 175 0.017
regulation of catabolic process GO:0009894 113 0.017
chromosome segregation GO:0007059 2 0.017
positive regulation of cell death GO:0010942 184 0.017
regulation of cellular catabolic process GO:0031329 101 0.017
response to glucocorticoid GO:0051384 223 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
positive regulation of cellular component organization GO:0051130 200 0.017
regulation of nucleotide metabolic process GO:0006140 117 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
positive regulation of cell projection organization GO:0031346 111 0.017
cellular ketone metabolic process GO:0042180 51 0.017
brain development GO:0007420 247 0.017
positive regulation of gtpase activity GO:0043547 47 0.017
asymmetric protein localization GO:0008105 2 0.017
synaptic transmission GO:0007268 235 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
positive regulation of cellular biosynthetic process GO:0031328 295 0.017
regulation of hormone levels GO:0010817 187 0.017
developmental process involved in reproduction GO:0003006 159 0.017
reproduction GO:0000003 245 0.017
regulation of cell development GO:0060284 263 0.017
cellular cation homeostasis GO:0030003 180 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
regulation of cell projection organization GO:0031344 175 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
guanosine containing compound metabolic process GO:1901068 74 0.016
cellular response to organic cyclic compound GO:0071407 202 0.016
learning or memory GO:0007611 90 0.016
positive regulation of nucleic acid templated transcription GO:1903508 197 0.016
anatomical structure morphogenesis GO:0009653 298 0.016
development of primary sexual characteristics GO:0045137 107 0.016
protein localization GO:0008104 191 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.016
regulation of neuron projection development GO:0010975 161 0.015
peptide hormone secretion GO:0030072 84 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
response to ketone GO:1901654 182 0.015
ion homeostasis GO:0050801 212 0.015
mapk cascade GO:0000165 140 0.015
adult locomotory behavior GO:0008344 4 0.015
regulation of blood circulation GO:1903522 110 0.015
nucleotide catabolic process GO:0009166 139 0.015
positive regulation of secretion by cell GO:1903532 128 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
cellular component assembly GO:0022607 360 0.015
cell adhesion GO:0007155 110 0.015
purine nucleoside triphosphate metabolic process GO:0009144 141 0.015
response to other organism GO:0051707 220 0.015
positive regulation of cell development GO:0010720 176 0.015
protein complex biogenesis GO:0070271 263 0.015
circulatory system process GO:0003013 183 0.015
axis specification GO:0009798 4 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
neuron death GO:0070997 127 0.014
regulation of nucleotide catabolic process GO:0030811 65 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
cytoplasmic transport GO:0016482 115 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
embryonic pattern specification GO:0009880 1 0.014
gtp metabolic process GO:0046039 72 0.014
gamete generation GO:0007276 124 0.014
positive regulation of protein modification process GO:0031401 142 0.014
secretion by cell GO:0032940 248 0.014
heart process GO:0003015 57 0.014
cell type specific apoptotic process GO:0097285 134 0.014
neuron projection morphogenesis GO:0048812 122 0.014
chemical homeostasis GO:0048878 292 0.014
regulation of gtp catabolic process GO:0033124 58 0.014
single organism behavior GO:0044708 130 0.014
multi organism reproductive process GO:0044703 262 0.014
mechanoreceptor differentiation GO:0042490 2 0.014
regulation of anatomical structure size GO:0090066 135 0.014
positive regulation of developmental process GO:0051094 283 0.014
organelle organization GO:0006996 266 0.014
response to radiation GO:0009314 137 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.013
response to metal ion GO:0010038 253 0.013
cellular protein localization GO:0034613 122 0.013
regulation of metal ion transport GO:0010959 118 0.013
signal release GO:0023061 145 0.013
nucleoside catabolic process GO:0009164 126 0.013
biological adhesion GO:0022610 110 0.013
aromatic compound catabolic process GO:0019439 168 0.013
ribonucleoside triphosphate metabolic process GO:0009199 141 0.013
response to hexose GO:0009746 144 0.013
nucleobase containing compound catabolic process GO:0034655 152 0.013
regeneration GO:0031099 163 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
nucleoside metabolic process GO:0009116 179 0.013
growth GO:0040007 165 0.013
axon ensheathment GO:0008366 40 0.013
positive regulation of apoptotic process GO:0043065 154 0.013
response to glucose GO:0009749 136 0.013
negative regulation of cell communication GO:0010648 158 0.013
regulation of cellular component biogenesis GO:0044087 86 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
cation homeostasis GO:0055080 195 0.013
divalent inorganic cation transport GO:0072511 134 0.013
regulation of ion transport GO:0043269 245 0.013
negative regulation of cell death GO:0060548 229 0.013
cellular response to lipid GO:0071396 201 0.013
negative regulation of molecular function GO:0044092 133 0.013
cell part morphogenesis GO:0032990 123 0.013
cell motility GO:0048870 202 0.013
response to peptide hormone GO:0043434 278 0.013
positive regulation of cellular catabolic process GO:0031331 71 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
positive regulation of neuron projection development GO:0010976 99 0.013
homeostatic process GO:0042592 331 0.013
response to growth factor GO:0070848 189 0.013
metal ion homeostasis GO:0055065 186 0.012
regulation of synaptic transmission GO:0050804 141 0.012
response to lipopolysaccharide GO:0032496 191 0.012
motor neuron axon guidance GO:0008045 1 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.012
cellular divalent inorganic cation homeostasis GO:0072503 162 0.012
response to monosaccharide GO:0034284 159 0.012
spindle organization GO:0007051 2 0.012
regulation of calcium ion transport GO:0051924 77 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
positive regulation of neuron differentiation GO:0045666 126 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
positive regulation of rna biosynthetic process GO:1902680 197 0.012
organophosphate catabolic process GO:0046434 148 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
secretion GO:0046903 307 0.012
cellular response to endogenous stimulus GO:0071495 377 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
sexual reproduction GO:0019953 148 0.012
regulation of protein transport GO:0051223 68 0.012
mesoderm development GO:0007498 2 0.012
cellular response to alcohol GO:0097306 87 0.011
calcium ion homeostasis GO:0055074 162 0.011
regulation of peptide secretion GO:0002791 82 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
positive regulation of catabolic process GO:0009896 78 0.011
neuron development GO:0048666 286 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
establishment of protein localization GO:0045184 141 0.011
negative regulation of gene expression GO:0010629 199 0.011
gonad development GO:0008406 104 0.011
ribonucleoside triphosphate catabolic process GO:0009203 122 0.011
endocytosis GO:0006897 84 0.011
divalent metal ion transport GO:0070838 132 0.011
peptide transport GO:0015833 97 0.011
negative regulation of transport GO:0051051 136 0.011
response to peptide GO:1901652 292 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
positive regulation of transport GO:0051050 245 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.011
myeloid leukocyte activation GO:0002274 36 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
regulation of cell differentiation GO:0045595 320 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
cellular response to steroid hormone stimulus GO:0071383 93 0.011
peptide secretion GO:0002790 86 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
negative regulation of macromolecule metabolic process GO:0010605 260 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
transcription from rna polymerase ii promoter GO:0006366 252 0.011
regulation of dendrite development GO:0050773 59 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
positive regulation of transcription dna templated GO:0045893 197 0.011
response to biotic stimulus GO:0009607 226 0.011
alcohol metabolic process GO:0006066 77 0.011
branched chain amino acid transport GO:0015803 2 0.011
regulation of small gtpase mediated signal transduction GO:0051056 48 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
calcium ion transport GO:0006816 131 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
amine metabolic process GO:0009308 38 0.010
asymmetric stem cell division GO:0098722 2 0.010
regulation of mapk cascade GO:0043408 116 0.010
regulation of transmembrane transport GO:0034762 122 0.010
insulin like growth factor receptor signaling pathway GO:0048009 3 0.010
nucleotide biosynthetic process GO:0009165 98 0.010
male gamete generation GO:0048232 99 0.010
cellular response to growth factor stimulus GO:0071363 162 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.010
purine nucleotide biosynthetic process GO:0006164 83 0.010
positive regulation of transferase activity GO:0051347 81 0.010
response to carbohydrate GO:0009743 183 0.010
positive regulation of mapk cascade GO:0043410 92 0.010
camp metabolic process GO:0046058 63 0.010
cell projection morphogenesis GO:0048858 123 0.010
positive regulation of rna metabolic process GO:0051254 203 0.010
protein complex subunit organization GO:0071822 302 0.010

Sarm1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.015
disease of anatomical entity DOID:7 0 0.013
nervous system disease DOID:863 0 0.013
gastrointestinal system disease DOID:77 0 0.011