Rattus norvegicus

0 known processes

Mll4

myeloid/lymphoid or mixed-lineage leukemia 4

(Aliases: RGD1308331,Wbp7)

Mll4 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
transcription dna templated GO:0006351 377 0.128
intracellular signal transduction GO:0035556 314 0.112
cellular component biogenesis GO:0044085 368 0.109
regulation of rna biosynthetic process GO:2001141 381 0.105
regulation of phosphorylation GO:0042325 248 0.097
regulation of rna metabolic process GO:0051252 391 0.087
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.085
organelle organization GO:0006996 266 0.079
Human
locomotion GO:0040011 237 0.078
positive regulation of biosynthetic process GO:0009891 319 0.071
regulation of cellular protein metabolic process GO:0032268 267 0.058
positive regulation of protein phosphorylation GO:0001934 135 0.058
rna biosynthetic process GO:0032774 380 0.056
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.055
positive regulation of protein metabolic process GO:0051247 178 0.055
positive regulation of molecular function GO:0044093 230 0.054
rna metabolic process GO:0016070 406 0.053
macromolecular complex subunit organization GO:0043933 339 0.053
Human
small gtpase mediated signal transduction GO:0007264 36 0.052
cellular lipid metabolic process GO:0044255 208 0.052
regulation of protein phosphorylation GO:0001932 183 0.051
nucleic acid templated transcription GO:0097659 379 0.051
regulation of phosphate metabolic process GO:0019220 349 0.051
regulation of catalytic activity GO:0050790 304 0.047
positive regulation of phosphate metabolic process GO:0045937 262 0.047
regulation of nucleic acid templated transcription GO:1903506 380 0.046
protein phosphorylation GO:0006468 345 0.046
multi multicellular organism process GO:0044706 138 0.046
regulation of phosphorus metabolic process GO:0051174 349 0.044
response to metal ion GO:0010038 253 0.044
Rat
cellular component movement GO:0006928 248 0.043
positive regulation of cell communication GO:0010647 271 0.042
negative regulation of cellular metabolic process GO:0031324 281 0.042
mapk cascade GO:0000165 140 0.040
regulation of protein modification process GO:0031399 194 0.040
positive regulation of protein modification process GO:0031401 142 0.040
neurological system process GO:0050877 219 0.039
positive regulation of rna metabolic process GO:0051254 203 0.039
regulation of protein kinase activity GO:0045859 105 0.038
positive regulation of response to stimulus GO:0048584 285 0.038
protein complex assembly GO:0006461 263 0.038
positive regulation of nucleic acid templated transcription GO:1903508 197 0.038
protein complex subunit organization GO:0071822 302 0.038
chromatin modification GO:0016568 33 0.038
Human
single organism catabolic process GO:0044712 283 0.037
transcription from rna polymerase ii promoter GO:0006366 252 0.036
anterior posterior pattern specification GO:0009952 1 0.036
positive regulation of gene expression GO:0010628 244 0.035
multi organism reproductive process GO:0044703 262 0.035
regulation of signal transduction GO:0009966 318 0.034
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.033
tissue development GO:0009888 252 0.033
programmed cell death GO:0012501 392 0.033
purine nucleotide metabolic process GO:0006163 229 0.032
cellular response to lipid GO:0071396 201 0.032
cellular response to stress GO:0033554 269 0.031
catabolic process GO:0009056 351 0.031
purine containing compound metabolic process GO:0072521 253 0.030
response to carbohydrate GO:0009743 183 0.030
positive regulation of multicellular organismal process GO:0051240 387 0.030
protein complex biogenesis GO:0070271 263 0.030
regulation of molecular function GO:0065009 398 0.029
regulation of system process GO:0044057 208 0.029
nucleotide metabolic process GO:0009117 279 0.029
negative regulation of transcription dna templated GO:0045892 116 0.029
regulation of intracellular signal transduction GO:1902531 218 0.029
single organism biosynthetic process GO:0044711 342 0.028
response to extracellular stimulus GO:0009991 380 0.027
positive regulation of signal transduction GO:0009967 175 0.027
cell motility GO:0048870 202 0.027
nucleoside phosphate metabolic process GO:0006753 283 0.027
immune system process GO:0002376 204 0.026
positive regulation of phosphorus metabolic process GO:0010562 262 0.026
response to nutrient levels GO:0031667 370 0.026
positive regulation of cellular protein metabolic process GO:0032270 167 0.026
regulation of defense response GO:0031347 68 0.026
nucleoside triphosphate catabolic process GO:0009143 123 0.026
positive regulation of transcription dna templated GO:0045893 197 0.026
regulation of kinase activity GO:0043549 117 0.026
signal transduction by phosphorylation GO:0023014 144 0.026
reproductive process GO:0022414 372 0.025
female pregnancy GO:0007565 122 0.025
spindle organization GO:0007051 2 0.025
activation of mapkkk activity GO:0000185 1 0.025
cellular component assembly GO:0022607 360 0.024
multicellular organism reproduction GO:0032504 233 0.024
positive regulation of transferase activity GO:0051347 81 0.024
glycosyl compound metabolic process GO:1901657 182 0.024
purine nucleoside metabolic process GO:0042278 169 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
purine ribonucleotide metabolic process GO:0009150 227 0.024
tube formation GO:0035148 3 0.023
ribonucleotide metabolic process GO:0009259 231 0.023
positive regulation of catalytic activity GO:0043085 184 0.023
regulation of transferase activity GO:0051338 123 0.023
response to biotic stimulus GO:0009607 226 0.023
positive regulation of neuron migration GO:2001224 2 0.023
nucleoside catabolic process GO:0009164 126 0.023
nucleoside triphosphate metabolic process GO:0009141 144 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.023
response to other organism GO:0051707 220 0.023
positive regulation of ion transport GO:0043270 94 0.022
organic hydroxy compound metabolic process GO:1901615 115 0.022
neuron differentiation GO:0030182 368 0.022
negative regulation of cell communication GO:0010648 158 0.022
response to lipopolysaccharide GO:0032496 191 0.022
ras protein signal transduction GO:0007265 29 0.022
regulation of transcription dna templated GO:0006355 374 0.022
response to external biotic stimulus GO:0043207 221 0.022
cellular catabolic process GO:0044248 295 0.021
negative regulation of cellular biosynthetic process GO:0031327 161 0.021
regulation of multicellular organismal development GO:2000026 376 0.021
mitotic spindle organization GO:0007052 2 0.021
dna metabolic process GO:0006259 96 0.021
regulation of jun kinase activity GO:0043506 10 0.021
localization of cell GO:0051674 202 0.021
positive regulation of apoptotic process GO:0043065 154 0.021
negative regulation of biosynthetic process GO:0009890 168 0.021
cellular amine metabolic process GO:0044106 38 0.021
cellular response to molecule of bacterial origin GO:0071219 56 0.020
positive regulation of cellular biosynthetic process GO:0031328 295 0.020
amine metabolic process GO:0009308 38 0.020
cellular response to endogenous stimulus GO:0071495 377 0.020
regulation of cell development GO:0060284 263 0.020
carboxylic acid metabolic process GO:0019752 289 0.020
apoptotic process GO:0006915 381 0.020
organic substance catabolic process GO:1901575 316 0.020
positive regulation of fatty acid transport GO:2000193 9 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
peptidyl amino acid modification GO:0018193 126 0.019
Human
regulation of cellular localization GO:0060341 263 0.019
chromosome organization GO:0051276 36 0.019
Human
regulation of mapk cascade GO:0043408 116 0.019
positive regulation of transport GO:0051050 245 0.019
regulation of small gtpase mediated signal transduction GO:0051056 48 0.019
regulation of protein metabolic process GO:0051246 289 0.019
nucleobase containing small molecule metabolic process GO:0055086 316 0.019
organic cyclic compound catabolic process GO:1901361 175 0.019
cell cell signaling GO:0007267 335 0.018
nucleotide catabolic process GO:0009166 139 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.018
small molecule biosynthetic process GO:0044283 124 0.018
response to mechanical stimulus GO:0009612 134 0.018
positive regulation of intracellular signal transduction GO:1902533 138 0.018
negative regulation of metabolic process GO:0009892 331 0.018
activation of protein kinase activity GO:0032147 47 0.018
regulation of catabolic process GO:0009894 113 0.018
organophosphate metabolic process GO:0019637 370 0.017
positive regulation of signaling GO:0023056 270 0.017
positive regulation of icosanoid secretion GO:0032305 7 0.017
regulation of canonical wnt signaling pathway GO:0060828 4 0.017
organic acid transport GO:0015849 116 0.017
defense response GO:0006952 194 0.017
response to bacterium GO:0009617 200 0.017
signal release GO:0023061 145 0.017
macromolecule localization GO:0033036 252 0.017
p38mapk cascade GO:0038066 1 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
positive regulation of protein kinase activity GO:0045860 73 0.017
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.016
heterocycle catabolic process GO:0046700 167 0.016
cellular response to metal ion GO:0071248 55 0.016
regulation of proteasomal protein catabolic process GO:0061136 4 0.016
positive regulation of map kinase activity GO:0043406 46 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
negative regulation of phosphorus metabolic process GO:0010563 80 0.016
protein oligomerization GO:0051259 191 0.016
positive regulation of mapk cascade GO:0043410 92 0.016
regulation of cell differentiation GO:0045595 320 0.016
lipid metabolic process GO:0006629 283 0.016
chromatin remodeling GO:0006338 3 0.016
cellular response to lipopolysaccharide GO:0071222 55 0.016
glucose metabolic process GO:0006006 52 0.016
single organism organelle organization GO:1902589 180 0.015
Human
positive regulation of nervous system development GO:0051962 178 0.015
peptide biosynthetic process GO:0043043 3 0.015
response to acid chemical GO:0001101 222 0.015
homeostatic process GO:0042592 331 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.015
organophosphate catabolic process GO:0046434 148 0.015
anion transport GO:0006820 178 0.015
response to monosaccharide GO:0034284 159 0.015
aromatic compound catabolic process GO:0019439 168 0.015
regulation of jnk cascade GO:0046328 19 0.015
actin filament based process GO:0030029 86 0.015
cellular homeostasis GO:0019725 252 0.014
positive regulation of rna biosynthetic process GO:1902680 197 0.014
negative regulation of macromolecule metabolic process GO:0010605 260 0.014
organophosphate biosynthetic process GO:0090407 143 0.014
carbohydrate derivative metabolic process GO:1901135 346 0.014
single organism reproductive process GO:0044702 297 0.014
actin filament organization GO:0007015 42 0.014
cell cycle GO:0007049 101 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.014
organonitrogen compound biosynthetic process GO:1901566 167 0.014
ribonucleoside metabolic process GO:0009119 174 0.014
cell cycle checkpoint GO:0000075 2 0.014
regulation of response to stress GO:0080134 126 0.014
purine nucleoside catabolic process GO:0006152 124 0.014
response to peptide GO:1901652 292 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.014
response to molecule of bacterial origin GO:0002237 194 0.014
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.013
regulation of cellular catabolic process GO:0031329 101 0.013
regulation of ion transport GO:0043269 245 0.013
regulation of activation of janus kinase activity GO:0010533 1 0.013
transmembrane transport GO:0055085 412 0.013
response to reactive oxygen species GO:0000302 120 0.013
ribonucleotide biosynthetic process GO:0009260 85 0.013
regulation of ion transmembrane transport GO:0034765 121 0.013
glycosyl compound catabolic process GO:1901658 126 0.013
response to nutrient GO:0007584 248 0.013
circadian regulation of gene expression GO:0032922 3 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
ribonucleoside triphosphate catabolic process GO:0009203 122 0.012
covalent chromatin modification GO:0016569 30 0.012
Human
regulation of nucleoside metabolic process GO:0009118 66 0.012
response to oxygen levels GO:0070482 265 0.012
proteolysis GO:0006508 175 0.012
synaptic transmission GO:0007268 235 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
behavior GO:0007610 205 0.012
nucleobase containing compound catabolic process GO:0034655 152 0.012
positive regulation of catabolic process GO:0009896 78 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
macromolecular complex assembly GO:0065003 273 0.012
regulation of cellular response to stress GO:0080135 49 0.012
oxoacid metabolic process GO:0043436 290 0.012
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
regulation of purine nucleotide metabolic process GO:1900542 115 0.012
single organism behavior GO:0044708 130 0.012
positive regulation of cell death GO:0010942 184 0.012
defense response to gram negative bacterium GO:0050829 3 0.012
negative regulation of signaling GO:0023057 157 0.011
cellular ketone metabolic process GO:0042180 51 0.011
response to transforming growth factor beta GO:0071559 46 0.011
response to inorganic substance GO:0010035 377 0.011
Rat
anatomical structure morphogenesis GO:0009653 298 0.011
negative regulation of innate immune response GO:0045824 4 0.011
sexual reproduction GO:0019953 148 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.011
response to ketone GO:1901654 182 0.011
regulation of neuron projection development GO:0010975 161 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
organic acid metabolic process GO:0006082 292 0.011
morphogenesis of embryonic epithelium GO:0016331 3 0.011
regulation of cell projection organization GO:0031344 175 0.011
cellular response to biotic stimulus GO:0071216 59 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
brain development GO:0007420 247 0.011
inflammatory response GO:0006954 150 0.011
reproduction GO:0000003 245 0.011
circulatory system development GO:0072359 134 0.011
neuron projection development GO:0031175 273 0.011
central nervous system development GO:0007417 311 0.011
gamete generation GO:0007276 124 0.011
positive regulation of stress activated mapk cascade GO:0032874 17 0.011
alcohol metabolic process GO:0006066 77 0.011
cell migration GO:0016477 197 0.011
cellular response to oxygen containing compound GO:1901701 386 0.011
regulation of hormone secretion GO:0046883 106 0.011
positive regulation of developmental process GO:0051094 283 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.010
ribonucleotide catabolic process GO:0009261 136 0.010
positive regulation of cell development GO:0010720 176 0.010
regulation of rab protein signal transduction GO:0032483 3 0.010
regulation of alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor activity GO:2000311 11 0.010
regulation of synaptic transmission GO:0050804 141 0.010
regulation of nervous system development GO:0051960 264 0.010
single organism carbohydrate metabolic process GO:0044723 118 0.010
regulation of cellular component movement GO:0051270 150 0.010
regulation of cell motility GO:2000145 131 0.010
hormone transport GO:0009914 121 0.010
negative regulation of rna biosynthetic process GO:1902679 118 0.010
positive regulation of organic acid transport GO:0032892 22 0.010
response to transition metal nanoparticle GO:1990267 122 0.010
salivary gland development GO:0007431 3 0.010

Mll4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014
vascular disease DOID:178 0 0.014
cardiovascular system disease DOID:1287 0 0.014