Rattus norvegicus

0 known processes

Eif2c1

eukaryotic translation initiation factor 2C, 1

Eif2c1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of multicellular organismal process GO:0051240 387 0.074
positive regulation of phosphate metabolic process GO:0045937 262 0.073
central nervous system development GO:0007417 311 0.072
cellular response to endogenous stimulus GO:0071495 377 0.067
brain development GO:0007420 247 0.067
regulation of cellular component organization GO:0051128 368 0.059
negative regulation of macromolecule metabolic process GO:0010605 260 0.058
Human
homeostatic process GO:0042592 331 0.055
cellular response to lipid GO:0071396 201 0.055
regulation of molecular function GO:0065009 398 0.052
dendrite development GO:0016358 72 0.051
regulation of multicellular organismal development GO:2000026 376 0.051
organelle organization GO:0006996 266 0.049
regulation of rna metabolic process GO:0051252 391 0.049
Mouse
cellular response to oxygen containing compound GO:1901701 386 0.047
neuron projection morphogenesis GO:0048812 122 0.047
regulation of anatomical structure morphogenesis GO:0022603 141 0.047
cell morphogenesis GO:0000902 142 0.046
regulation of nervous system development GO:0051960 264 0.046
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.046
Mouse
positive regulation of transport GO:0051050 245 0.045
regulation of neurogenesis GO:0050767 247 0.045
amine metabolic process GO:0009308 38 0.044
head development GO:0060322 247 0.042
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.042
regulation of cell development GO:0060284 263 0.041
gland development GO:0048732 155 0.041
regulation of cell differentiation GO:0045595 320 0.040
regulation of neuron differentiation GO:0045664 208 0.040
reproduction GO:0000003 245 0.040
positive regulation of developmental process GO:0051094 283 0.038
regulation of phosphorylation GO:0042325 248 0.038
cell projection organization GO:0030030 302 0.037
ion transmembrane transport GO:0034220 365 0.037
positive regulation of nervous system development GO:0051962 178 0.035
multicellular organismal reproductive process GO:0048609 233 0.034
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.033
intracellular signal transduction GO:0035556 314 0.033
regulation of cellular amine metabolic process GO:0033238 8 0.033
regulation of anatomical structure size GO:0090066 135 0.032
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.032
Mouse
neurotransmitter gated ion channel clustering GO:0072578 3 0.032
secretion by cell GO:0032940 248 0.031
positive regulation of cellular component organization GO:0051130 200 0.031
nucleic acid templated transcription GO:0097659 379 0.031
Mouse
regulation of phosphorus metabolic process GO:0051174 349 0.031
oxoacid metabolic process GO:0043436 290 0.031
regulation of cellular ketone metabolic process GO:0010565 27 0.030
synaptic transmission GO:0007268 235 0.030
positive regulation of synapse maturation GO:0090129 2 0.030
chemical homeostasis GO:0048878 292 0.030
negative regulation of metabolic process GO:0009892 331 0.030
Human
regulation of nucleic acid templated transcription GO:1903506 380 0.029
Mouse
negative regulation of cellular metabolic process GO:0031324 281 0.029
Human
axis specification GO:0009798 4 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.029
Mouse
cell part morphogenesis GO:0032990 123 0.029
response to growth factor GO:0070848 189 0.029
regulation of signal transduction GO:0009966 318 0.029
neuron differentiation GO:0030182 368 0.029
regulation of rna biosynthetic process GO:2001141 381 0.029
Mouse
macromolecular complex subunit organization GO:0043933 339 0.029
regulation of cell projection organization GO:0031344 175 0.028
single organism organelle organization GO:1902589 180 0.028
regulation of cellular localization GO:0060341 263 0.028
single organism reproductive process GO:0044702 297 0.028
carboxylic acid metabolic process GO:0019752 289 0.028
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.028
Human
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
behavior GO:0007610 205 0.028
regulation of protein phosphorylation GO:0001932 183 0.028
regulation of neuron projection development GO:0010975 161 0.028
multicellular organism reproduction GO:0032504 233 0.027
cellular amine metabolic process GO:0044106 38 0.027
response to lipopolysaccharide GO:0032496 191 0.027
positive regulation of phosphorus metabolic process GO:0010562 262 0.026
cell cell signaling GO:0007267 335 0.026
organic acid metabolic process GO:0006082 292 0.026
cellular homeostasis GO:0019725 252 0.026
reproductive process GO:0022414 372 0.026
multi organism reproductive process GO:0044703 262 0.025
locomotion GO:0040011 237 0.025
positive regulation of neurogenesis GO:0050769 165 0.025
cellular component assembly GO:0022607 360 0.024
cellular response to growth factor stimulus GO:0071363 162 0.024
cellular component morphogenesis GO:0032989 155 0.024
taxis GO:0042330 67 0.024
eye morphogenesis GO:0048592 4 0.024
cell growth GO:0016049 104 0.024
positive regulation of molecular function GO:0044093 230 0.023
cell migration GO:0016477 197 0.023
positive regulation of response to stimulus GO:0048584 285 0.023
positive regulation of cellular amine metabolic process GO:0033240 3 0.023
programmed cell death GO:0012501 392 0.023
rhythmic process GO:0048511 156 0.022
neuron projection development GO:0031175 273 0.022
positive regulation of cell differentiation GO:0045597 217 0.022
positive regulation of neuron differentiation GO:0045666 126 0.022
neurological system process GO:0050877 219 0.022
anterior posterior pattern specification GO:0009952 1 0.022
enzyme linked receptor protein signaling pathway GO:0007167 116 0.022
regulation of secretion GO:0051046 224 0.022
regulation of synaptic plasticity GO:0048167 70 0.022
cellular amino acid metabolic process GO:0006520 107 0.022
regulation of catalytic activity GO:0050790 304 0.022
mapk cascade GO:0000165 140 0.022
purine containing compound metabolic process GO:0072521 253 0.021
regulation of programmed cell death GO:0043067 341 0.021
developmental process involved in reproduction GO:0003006 159 0.021
cellular component biogenesis GO:0044085 368 0.021
nucleobase containing small molecule metabolic process GO:0055086 316 0.021
cellular ketone metabolic process GO:0042180 51 0.021
positive regulation of neuron projection development GO:0010976 99 0.021
regulation of secretion by cell GO:1903530 208 0.021
regulation of kinase activity GO:0043549 117 0.021
calcium ion homeostasis GO:0055074 162 0.020
regulation of cell proliferation GO:0042127 359 0.020
synapse organization GO:0050808 46 0.020
regulation of synaptic transmission GO:0050804 141 0.020
single organism catabolic process GO:0044712 283 0.020
secretion GO:0046903 307 0.019
cell projection morphogenesis GO:0048858 123 0.019
positive regulation of cell projection organization GO:0031346 111 0.019
rna metabolic process GO:0016070 406 0.019
Human Mouse
cell morphogenesis involved in differentiation GO:0000904 119 0.019
metal ion homeostasis GO:0055065 186 0.019
ras protein signal transduction GO:0007265 29 0.019
positive regulation of gene expression GO:0010628 244 0.019
Mouse
negative regulation of biosynthetic process GO:0009890 168 0.019
Human
negative regulation of molecular function GO:0044092 133 0.019
regulation of dendrite development GO:0050773 59 0.019
cellular component movement GO:0006928 248 0.019
positive regulation of cell proliferation GO:0008284 249 0.019
endocytosis GO:0006897 84 0.019
regulation of transcription dna templated GO:0006355 374 0.019
Mouse
regulation of protein kinase activity GO:0045859 105 0.018
cytoskeleton organization GO:0007010 111 0.018
embryo development GO:0009790 49 0.018
muscle structure development GO:0061061 87 0.018
regulation of actin cytoskeleton organization GO:0032956 30 0.018
actin filament based process GO:0030029 86 0.018
localization of cell GO:0051674 202 0.018
response to biotic stimulus GO:0009607 226 0.018
negative regulation of cellular component organization GO:0051129 83 0.018
growth GO:0040007 165 0.018
cytoplasmic transport GO:0016482 115 0.018
regulation of cellular component biogenesis GO:0044087 86 0.017
response to acid chemical GO:0001101 222 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
calcium mediated signaling using intracellular calcium source GO:0035584 1 0.017
anatomical structure morphogenesis GO:0009653 298 0.017
negative regulation of rna metabolic process GO:0051253 123 0.017
positive regulation of mapk cascade GO:0043410 92 0.017
response to bacterium GO:0009617 200 0.016
nucleoside phosphate metabolic process GO:0006753 283 0.016
response to estrogen GO:0043627 232 0.016
single organism intracellular transport GO:1902582 166 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
retinal ganglion cell axon guidance GO:0031290 1 0.016
regulation of phosphate metabolic process GO:0019220 349 0.016
cellular response to nitrogen compound GO:1901699 210 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
regulation of cell morphogenesis GO:0022604 77 0.016
protein phosphorylation GO:0006468 345 0.016
vesicle mediated transport GO:0016192 181 0.016
response to inorganic substance GO:0010035 377 0.016
regulation of protein modification process GO:0031399 194 0.016
nucleotide metabolic process GO:0009117 279 0.016
response to hypoxia GO:0001666 231 0.016
organophosphate metabolic process GO:0019637 370 0.016
positive regulation of cellular protein metabolic process GO:0032270 167 0.016
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 2 0.016
positive regulation of signaling GO:0023056 270 0.016
spindle organization GO:0007051 2 0.016
lipid metabolic process GO:0006629 283 0.016
regulation of synapse maturation GO:0090128 2 0.015
response to estradiol GO:0032355 164 0.015
positive regulation of cell development GO:0010720 176 0.015
response to decreased oxygen levels GO:0036293 237 0.015
peptidyl tyrosine modification GO:0018212 72 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
regulation of system process GO:0044057 208 0.015
negative regulation of protein metabolic process GO:0051248 114 0.015
Human
regulation of cellular protein metabolic process GO:0032268 267 0.015
Human
gamete generation GO:0007276 124 0.015
immune system process GO:0002376 204 0.015
regulation of protein transport GO:0051223 68 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
neuromuscular process GO:0050905 2 0.015
positive regulation of cellular biosynthetic process GO:0031328 295 0.015
Mouse
actin cytoskeleton organization GO:0030036 73 0.015
negative regulation of gene expression GO:0010629 199 0.015
Human
cardiovascular system development GO:0072358 134 0.015
regulation of ion transport GO:0043269 245 0.014
cell motility GO:0048870 202 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
positive regulation of secretion GO:0051047 140 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.014
motor neuron axon guidance GO:0008045 1 0.014
development of primary sexual characteristics GO:0045137 107 0.014
neuron death GO:0070997 127 0.014
hepaticobiliary system development GO:0061008 90 0.014
transmembrane transport GO:0055085 412 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
striated muscle cell development GO:0055002 26 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
negative regulation of cell death GO:0060548 229 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
regulation of apoptotic process GO:0042981 335 0.014
cation homeostasis GO:0055080 195 0.014
cytosolic calcium ion homeostasis GO:0051480 140 0.014
regulation of metal ion transport GO:0010959 118 0.014
transcription dna templated GO:0006351 377 0.014
Mouse
purine nucleotide biosynthetic process GO:0006164 83 0.014
gastrulation GO:0007369 2 0.014
response to glucocorticoid GO:0051384 223 0.014
response to oxygen levels GO:0070482 265 0.014
purine ribonucleotide metabolic process GO:0009150 227 0.014
regulation of vasculature development GO:1901342 44 0.013
regulation of protein metabolic process GO:0051246 289 0.013
Human
sex differentiation GO:0007548 113 0.013
tissue development GO:0009888 252 0.013
regulation of protein localization GO:0032880 81 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.013
male gamete generation GO:0048232 99 0.013
sexual reproduction GO:0019953 148 0.013
regulation of nucleotide metabolic process GO:0006140 117 0.013
cytoskeleton dependent cytokinesis GO:0061640 2 0.013
response to extracellular stimulus GO:0009991 380 0.013
negative regulation of cell proliferation GO:0008285 119 0.013
positive regulation of nucleotide metabolic process GO:0045981 91 0.013
chemotaxis GO:0006935 66 0.013
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.013
positive regulation of cell death GO:0010942 184 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
intracellular receptor signaling pathway GO:0030522 35 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
Human
forebrain development GO:0030900 98 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
reproductive structure development GO:0048608 128 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
transcription from rna polymerase ii promoter GO:0006366 252 0.013
Mouse
cellular response to acid chemical GO:0071229 75 0.013
ion homeostasis GO:0050801 212 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.012
rna biosynthetic process GO:0032774 380 0.012
Mouse
microtubule organizing center organization GO:0031023 1 0.012
regulation of transferase activity GO:0051338 123 0.012
cellular macromolecular complex assembly GO:0034622 58 0.012
regulation of cell growth GO:0001558 85 0.012
n methyl d aspartate receptor clustering GO:0097114 2 0.012
developmental growth GO:0048589 100 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
Human
circulatory system development GO:0072359 134 0.012
positive regulation of rna biosynthetic process GO:1902680 197 0.012
Mouse
cellular chemical homeostasis GO:0055082 247 0.012
synapse assembly GO:0007416 29 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
axonogenesis GO:0007409 71 0.012
dendrite morphogenesis GO:0048813 43 0.012
reproductive system development GO:0061458 128 0.012
inorganic cation transmembrane transport GO:0098662 202 0.012
liver development GO:0001889 90 0.012
cellular response to organic cyclic compound GO:0071407 202 0.012
positive regulation of biosynthetic process GO:0009891 319 0.012
Mouse
regulation of cytoskeleton organization GO:0051493 49 0.012
chromatin remodeling GO:0006338 3 0.012
embryonic pattern specification GO:0009880 1 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
camera type eye morphogenesis GO:0048593 2 0.012
cellular response to alcohol GO:0097306 87 0.011
divalent inorganic cation homeostasis GO:0072507 165 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
single organism behavior GO:0044708 130 0.011
ovulation cycle GO:0042698 67 0.011
carbohydrate homeostasis GO:0033500 75 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
protein complex assembly GO:0006461 263 0.011
regulation of growth GO:0040008 105 0.011
nucleoside triphosphate metabolic process GO:0009141 144 0.011
intracellular transport GO:0046907 185 0.011
purine nucleotide catabolic process GO:0006195 136 0.011
cation transport GO:0006812 382 0.011
mitotic spindle organization GO:0007052 2 0.011
calcium ion transport GO:0006816 131 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
response to nutrient levels GO:0031667 370 0.011
positive regulation of cyclic nucleotide metabolic process GO:0030801 37 0.011
response to carbohydrate GO:0009743 183 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.011
regulation of transporter activity GO:0032409 50 0.011
axon development GO:0061564 96 0.011
multicellular organism growth GO:0035264 1 0.011
response to peptide hormone GO:0043434 278 0.011
response to glucose GO:0009749 136 0.011
cognition GO:0050890 92 0.011
cell adhesion GO:0007155 110 0.011
protein complex subunit organization GO:0071822 302 0.010
positive regulation of cell growth GO:0030307 44 0.010
nucleoside metabolic process GO:0009116 179 0.010
cellular response to biotic stimulus GO:0071216 59 0.010
protein complex biogenesis GO:0070271 263 0.010
signal release GO:0023061 145 0.010
regulation of hormone levels GO:0010817 187 0.010
immune response GO:0006955 104 0.010
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.010
positive regulation of signal transduction GO:0009967 175 0.010
response to external biotic stimulus GO:0043207 221 0.010
developmental growth involved in morphogenesis GO:0060560 33 0.010
negative regulation of response to stimulus GO:0048585 155 0.010
negative regulation of apoptotic process GO:0043066 181 0.010
negative regulation of signaling GO:0023057 157 0.010
neuron development GO:0048666 286 0.010
regulation of transmembrane transport GO:0034762 122 0.010
tube development GO:0035295 89 0.010
purine ribonucleoside metabolic process GO:0046128 168 0.010
cell type specific apoptotic process GO:0097285 134 0.010

Eif2c1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org