Rattus norvegicus

29 known processes

Pqlc2

PQ loop repeat containing 2

Pqlc2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carboxylic acid transport GO:0046942 115 0.098
anion transport GO:0006820 178 0.097
organic anion transport GO:0015711 132 0.096
regulation of programmed cell death GO:0043067 341 0.092
regulation of cell proliferation GO:0042127 359 0.092
negative regulation of transcription dna templated GO:0045892 116 0.081
metal ion transport GO:0030001 289 0.076
regulation of multicellular organismal development GO:2000026 376 0.075
reproductive process GO:0022414 372 0.072
amino acid transport GO:0006865 70 0.069
neuron development GO:0048666 286 0.067
organic acid metabolic process GO:0006082 292 0.065
single organism reproductive process GO:0044702 297 0.064
positive regulation of cell proliferation GO:0008284 249 0.064
reproduction GO:0000003 245 0.063
positive regulation of cellular biosynthetic process GO:0031328 295 0.062
regulation of cell differentiation GO:0045595 320 0.061
positive regulation of developmental process GO:0051094 283 0.060
negative regulation of cell proliferation GO:0008285 119 0.060
positive regulation of multicellular organismal process GO:0051240 387 0.058
macromolecule localization GO:0033036 252 0.056
organic acid transport GO:0015849 116 0.055
carboxylic acid metabolic process GO:0019752 289 0.054
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.053
negative regulation of cell death GO:0060548 229 0.053
single organism cellular localization GO:1902580 102 0.052
oxoacid metabolic process GO:0043436 290 0.052
multicellular organismal reproductive process GO:0048609 233 0.052
programmed cell death GO:0012501 392 0.051
vesicle mediated transport GO:0016192 181 0.051
secretion GO:0046903 307 0.050
anatomical structure morphogenesis GO:0009653 298 0.049
multicellular organism reproduction GO:0032504 233 0.048
regulation of apoptotic process GO:0042981 335 0.047
regulation of rna metabolic process GO:0051252 391 0.045
cellular component movement GO:0006928 248 0.045
neuron projection development GO:0031175 273 0.045
transmembrane transport GO:0055085 412 0.044
metal ion homeostasis GO:0055065 186 0.044
apoptotic process GO:0006915 381 0.044
cellular macromolecule localization GO:0070727 122 0.042
regulation of cell development GO:0060284 263 0.042
cellular component assembly GO:0022607 360 0.041
ovulation cycle GO:0042698 67 0.041
cellular response to oxygen containing compound GO:1901701 386 0.041
neuron differentiation GO:0030182 368 0.041
membrane organization GO:0061024 94 0.041
rhythmic process GO:0048511 156 0.040
positive regulation of signaling GO:0023056 270 0.040
positive regulation of cellular component organization GO:0051130 200 0.040
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.040
regulation of nervous system development GO:0051960 264 0.040
positive regulation of cell differentiation GO:0045597 217 0.039
regulation of cellular component organization GO:0051128 368 0.039
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.039
negative regulation of macromolecule metabolic process GO:0010605 260 0.039
regulation of nucleic acid templated transcription GO:1903506 380 0.039
response to external biotic stimulus GO:0043207 221 0.038
regulation of cellular amine metabolic process GO:0033238 8 0.037
cellular response to endogenous stimulus GO:0071495 377 0.037
response to nutrient levels GO:0031667 370 0.037
chemical homeostasis GO:0048878 292 0.037
cell projection organization GO:0030030 302 0.037
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.037
response to biotic stimulus GO:0009607 226 0.037
central nervous system development GO:0007417 311 0.037
brain development GO:0007420 247 0.036
response to oxidative stress GO:0006979 186 0.035
regulation of neurogenesis GO:0050767 247 0.035
head development GO:0060322 247 0.035
catabolic process GO:0009056 351 0.035
positive regulation of biosynthetic process GO:0009891 319 0.035
positive regulation of gene expression GO:0010628 244 0.034
regulation of protein metabolic process GO:0051246 289 0.034
single organism intracellular transport GO:1902582 166 0.033
developmental process involved in reproduction GO:0003006 159 0.033
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.033
response to bacterium GO:0009617 200 0.033
neuron projection morphogenesis GO:0048812 122 0.033
cellular chemical homeostasis GO:0055082 247 0.032
intracellular signal transduction GO:0035556 314 0.032
organelle organization GO:0006996 266 0.032
intracellular transport GO:0046907 185 0.031
tube development GO:0035295 89 0.031
transcription from rna polymerase ii promoter GO:0006366 252 0.031
cellular amino acid metabolic process GO:0006520 107 0.031
positive regulation of rna metabolic process GO:0051254 203 0.031
regulation of cellular amino acid metabolic process GO:0006521 2 0.031
positive regulation of mitochondrion organization GO:0010822 4 0.031
response to estrogen GO:0043627 232 0.030
regulation of catalytic activity GO:0050790 304 0.030
positive regulation of cell death GO:0010942 184 0.030
response to estradiol GO:0032355 164 0.030
negative regulation of nucleic acid templated transcription GO:1903507 117 0.030
cell projection morphogenesis GO:0048858 123 0.030
regulation of molecular function GO:0065009 398 0.029
nitrogen compound transport GO:0071705 229 0.029
cellular ketone metabolic process GO:0042180 51 0.029
multi organism reproductive process GO:0044703 262 0.029
negative regulation of metabolic process GO:0009892 331 0.029
peptidyl amino acid modification GO:0018193 126 0.028
cardiovascular system development GO:0072358 134 0.028
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.028
negative regulation of cellular biosynthetic process GO:0031327 161 0.028
negative regulation of biosynthetic process GO:0009890 168 0.028
regulation of rna biosynthetic process GO:2001141 381 0.028
response to other organism GO:0051707 220 0.027
positive regulation of programmed cell death GO:0043068 157 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.027
locomotion GO:0040011 237 0.027
nucleic acid templated transcription GO:0097659 379 0.027
response to light stimulus GO:0009416 52 0.027
rna metabolic process GO:0016070 406 0.027
organophosphate metabolic process GO:0019637 370 0.027
positive regulation of cell communication GO:0010647 271 0.026
sex differentiation GO:0007548 113 0.026
positive regulation of signal transduction GO:0009967 175 0.026
peptidyl tyrosine phosphorylation GO:0018108 72 0.025
cell cell signaling GO:0007267 335 0.025
cellular protein localization GO:0034613 122 0.025
regulation of neuron differentiation GO:0045664 208 0.025
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.024
positive regulation of cell development GO:0010720 176 0.024
gastrulation GO:0007369 2 0.024
organic substance catabolic process GO:1901575 316 0.024
cellular response to stress GO:0033554 269 0.024
regulation of signal transduction GO:0009966 318 0.024
regulation of cell projection organization GO:0031344 175 0.024
localization of cell GO:0051674 202 0.024
muscle structure development GO:0061061 87 0.024
regulation of neuron projection development GO:0010975 161 0.024
cellular response to abiotic stimulus GO:0071214 85 0.024
ribose phosphate metabolic process GO:0019693 235 0.023
aging GO:0007568 241 0.023
lipid biosynthetic process GO:0008610 128 0.023
positive regulation of nucleic acid templated transcription GO:1903508 197 0.023
regulation of intracellular signal transduction GO:1902531 218 0.023
growth GO:0040007 165 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.023
negative regulation of cell communication GO:0010648 158 0.022
cellular amine metabolic process GO:0044106 38 0.022
transcription dna templated GO:0006351 377 0.022
secretion by cell GO:0032940 248 0.022
cellular response to hormone stimulus GO:0032870 247 0.022
negative regulation of transport GO:0051051 136 0.022
cell part morphogenesis GO:0032990 123 0.022
positive regulation of molecular function GO:0044093 230 0.022
small molecule biosynthetic process GO:0044283 124 0.022
hormone metabolic process GO:0042445 69 0.022
negative regulation of cellular metabolic process GO:0031324 281 0.021
positive regulation of cellular amine metabolic process GO:0033240 3 0.021
response to inorganic substance GO:0010035 377 0.021
cellular lipid metabolic process GO:0044255 208 0.021
cellular homeostasis GO:0019725 252 0.021
positive regulation of rna biosynthetic process GO:1902680 197 0.021
cell type specific apoptotic process GO:0097285 134 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.021
regulation of cellular localization GO:0060341 263 0.021
multi multicellular organism process GO:0044706 138 0.020
protein phosphorylation GO:0006468 345 0.020
sexual reproduction GO:0019953 148 0.020
positive regulation of catalytic activity GO:0043085 184 0.020
carboxylic acid biosynthetic process GO:0046394 83 0.020
regulation of ion transport GO:0043269 245 0.020
response to ketone GO:1901654 182 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.020
cation homeostasis GO:0055080 195 0.019
cellular cation homeostasis GO:0030003 180 0.019
cellular component morphogenesis GO:0032989 155 0.019
positive regulation of neurogenesis GO:0050769 165 0.019
positive regulation of transport GO:0051050 245 0.019
positive regulation of phosphorus metabolic process GO:0010562 262 0.019
positive regulation of cellular protein metabolic process GO:0032270 167 0.019
regulation of system process GO:0044057 208 0.019
axon development GO:0061564 96 0.019
rna biosynthetic process GO:0032774 380 0.019
response to cytokine GO:0034097 215 0.018
cellular ion homeostasis GO:0006873 184 0.018
negative regulation of response to stimulus GO:0048585 155 0.018
amide transport GO:0042886 105 0.018
lipid metabolic process GO:0006629 283 0.018
organic acid biosynthetic process GO:0016053 83 0.018
single organism organelle organization GO:1902589 180 0.018
regulation of hormone levels GO:0010817 187 0.018
amine metabolic process GO:0009308 38 0.018
single organism membrane organization GO:0044802 74 0.018
jak stat cascade GO:0007259 26 0.018
regulation of transcription dna templated GO:0006355 374 0.018
positive regulation of phosphorylation GO:0042327 177 0.017
tissue development GO:0009888 252 0.017
regulation of cell motility GO:2000145 131 0.017
single organism biosynthetic process GO:0044711 342 0.017
regulation of phosphorus metabolic process GO:0051174 349 0.017
cellular component biogenesis GO:0044085 368 0.017
response to radiation GO:0009314 137 0.016
peptide transport GO:0015833 97 0.016
female pregnancy GO:0007565 122 0.016
monocarboxylic acid transport GO:0015718 52 0.016
cellular response to oxidative stress GO:0034599 76 0.016
regulation of phosphorylation GO:0042325 248 0.016
regulation of anatomical structure size GO:0090066 135 0.016
cell migration GO:0016477 197 0.016
female sex differentiation GO:0046660 59 0.016
cellular metal ion homeostasis GO:0006875 172 0.016
response to mechanical stimulus GO:0009612 134 0.016
positive regulation of apoptotic process GO:0043065 154 0.015
intestinal absorption GO:0050892 3 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
multicellular organismal homeostasis GO:0048871 49 0.015
steroid biosynthetic process GO:0006694 48 0.015
oligopeptide transport GO:0006857 4 0.015
negative regulation of programmed cell death GO:0043069 183 0.015
synaptic transmission GO:0007268 235 0.015
signal transduction by phosphorylation GO:0023014 144 0.015
response to lipopolysaccharide GO:0032496 191 0.015
blood circulation GO:0008015 183 0.015
cellular response to reactive oxygen species GO:0034614 55 0.015
positive regulation of nervous system development GO:0051962 178 0.015
mesoderm development GO:0007498 2 0.015
cellular response to organic cyclic compound GO:0071407 202 0.015
regulation of neuron death GO:1901214 115 0.015
development of primary sexual characteristics GO:0045137 107 0.015
positive regulation of neuron projection development GO:0010976 99 0.015
positive regulation of protein metabolic process GO:0051247 178 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
cell morphogenesis GO:0000902 142 0.014
neuron death GO:0070997 127 0.014
proteolysis GO:0006508 175 0.014
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
response to purine containing compound GO:0014074 126 0.014
negative regulation of secretion GO:0051048 82 0.014
cellular amide metabolic process GO:0043603 44 0.014
establishment of protein localization GO:0045184 141 0.014
nucleobase containing small molecule metabolic process GO:0055086 316 0.014
developmental growth GO:0048589 100 0.014
single organism catabolic process GO:0044712 283 0.014
response to peptide hormone GO:0043434 278 0.014
cellular modified amino acid metabolic process GO:0006575 61 0.014
regulation of response to external stimulus GO:0032101 106 0.014
cation transmembrane transport GO:0098655 263 0.014
cellular response to external stimulus GO:0071496 118 0.013
negative regulation of apoptotic process GO:0043066 181 0.013
cellular response to lipid GO:0071396 201 0.013
cell growth GO:0016049 104 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
alcohol metabolic process GO:0006066 77 0.013
anterior posterior pattern specification GO:0009952 1 0.013
epithelial cell differentiation GO:0030855 71 0.013
behavior GO:0007610 205 0.013
negative regulation of molecular function GO:0044092 133 0.013
regulation of cellular protein metabolic process GO:0032268 267 0.013
positive regulation of response to stimulus GO:0048584 285 0.013
anatomical structure formation involved in morphogenesis GO:0048646 83 0.013
negative regulation of gene expression GO:0010629 199 0.013
heterocycle catabolic process GO:0046700 167 0.013
lipid transport GO:0006869 61 0.013
response to wounding GO:0009611 254 0.013
negative regulation of neurogenesis GO:0050768 78 0.013
regulation of cell migration GO:0030334 128 0.013
positive regulation of transcription dna templated GO:0045893 197 0.013
regulation of protein localization GO:0032880 81 0.013
positive regulation of cellular component movement GO:0051272 102 0.013
single organism carbohydrate metabolic process GO:0044723 118 0.013
purine containing compound metabolic process GO:0072521 253 0.013
steroid metabolic process GO:0008202 73 0.013
toxin transport GO:1901998 3 0.012
ras protein signal transduction GO:0007265 29 0.012
purine nucleotide metabolic process GO:0006163 229 0.012
mitochondrion organization GO:0007005 35 0.012
protein transport GO:0015031 132 0.012
nucleoside phosphate metabolic process GO:0006753 283 0.012
negative regulation of neuron differentiation GO:0045665 62 0.012
regulation of cell morphogenesis GO:0022604 77 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.012
cellular response to peptide GO:1901653 133 0.012
immune system process GO:0002376 204 0.012
embryonic pattern specification GO:0009880 1 0.012
regulation of phosphate metabolic process GO:0019220 349 0.012
activation of protein kinase activity GO:0032147 47 0.012
reproductive system development GO:0061458 128 0.012
response to molecule of bacterial origin GO:0002237 194 0.012
hormone transport GO:0009914 121 0.012
response to extracellular stimulus GO:0009991 380 0.012
gamete generation GO:0007276 124 0.012
cytoplasmic transport GO:0016482 115 0.012
ion homeostasis GO:0050801 212 0.011
positive regulation of cell motility GO:2000147 97 0.011
response to axon injury GO:0048678 59 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
negative regulation of neuron death GO:1901215 69 0.011
sensory organ development GO:0007423 74 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
regulation of epithelial cell proliferation GO:0050678 49 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
circulatory system development GO:0072359 134 0.011
response to antibiotic GO:0046677 39 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
cellular response to extracellular stimulus GO:0031668 73 0.011
cellular response to steroid hormone stimulus GO:0071383 93 0.011
heart morphogenesis GO:0003007 3 0.011
carbohydrate derivative metabolic process GO:1901135 346 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
response to ethanol GO:0045471 162 0.011
negative regulation of signaling GO:0023057 157 0.011
cation transport GO:0006812 382 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
maintenance of location GO:0051235 17 0.011
protein localization GO:0008104 191 0.011
oxidation reduction process GO:0055114 304 0.011
organ morphogenesis GO:0009887 75 0.011
cellular response to nitrogen compound GO:1901699 210 0.011
gonad development GO:0008406 104 0.011
spermatogenesis GO:0007283 99 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
response to reactive oxygen species GO:0000302 120 0.011
lipid localization GO:0010876 62 0.011
regulation of blood pressure GO:0008217 83 0.011
sulfur compound metabolic process GO:0006790 70 0.011
motor neuron axon guidance GO:0008045 1 0.011
cytoskeleton dependent cytokinesis GO:0061640 2 0.011
response to alkaloid GO:0043279 132 0.011
divalent inorganic cation transport GO:0072511 134 0.010
positive regulation of intracellular signal transduction GO:1902533 138 0.010
regulation of protein kinase activity GO:0045859 105 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
peptidyl tyrosine modification GO:0018212 72 0.010
regulation of locomotion GO:0040012 148 0.010
dendrite development GO:0016358 72 0.010
cell motility GO:0048870 202 0.010
appendage morphogenesis GO:0035107 4 0.010
blood vessel development GO:0001568 69 0.010
macromolecular complex assembly GO:0065003 273 0.010
ribonucleoside metabolic process GO:0009119 174 0.010
response to nutrient GO:0007584 248 0.010
peptide secretion GO:0002790 86 0.010
epithelial cell proliferation GO:0050673 54 0.010
muscle cell proliferation GO:0033002 84 0.010
digestive tract development GO:0048565 39 0.010
neurological system process GO:0050877 219 0.010
cell cell signaling involved in cell fate commitment GO:0045168 2 0.010
multicellular organism growth GO:0035264 1 0.010

Pqlc2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.015
disease of anatomical entity DOID:7 0 0.015
nervous system disease DOID:863 0 0.015
central nervous system disease DOID:331 0 0.014
musculoskeletal system disease DOID:17 0 0.013