Rattus norvegicus

0 known processes

Pof1b

premature ovarian failure 1B

(Aliases: RGD1560798)

Pof1b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of protein metabolic process GO:0051246 289 0.067
reproductive process GO:0022414 372 0.066
regulation of phosphorus metabolic process GO:0051174 349 0.064
regulation of molecular function GO:0065009 398 0.054
cellular response to lipid GO:0071396 201 0.050
response to decreased oxygen levels GO:0036293 237 0.048
response to extracellular stimulus GO:0009991 380 0.047
oxoacid metabolic process GO:0043436 290 0.046
regulation of phosphate metabolic process GO:0019220 349 0.046
regulation of cellular component organization GO:0051128 368 0.046
regulation of cell proliferation GO:0042127 359 0.045
response to inorganic substance GO:0010035 377 0.045
cellular ketone metabolic process GO:0042180 51 0.045
multi organism reproductive process GO:0044703 262 0.045
positive regulation of biosynthetic process GO:0009891 319 0.044
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.044
cellular component biogenesis GO:0044085 368 0.044
organic acid metabolic process GO:0006082 292 0.043
intracellular signal transduction GO:0035556 314 0.043
organelle organization GO:0006996 266 0.042
regulation of cellular ketone metabolic process GO:0010565 27 0.041
cellular response to oxygen containing compound GO:1901701 386 0.041
response to nutrient levels GO:0031667 370 0.041
nucleic acid templated transcription GO:0097659 379 0.039
positive regulation of multicellular organismal process GO:0051240 387 0.039
multicellular organism reproduction GO:0032504 233 0.039
single organism reproductive process GO:0044702 297 0.039
cellular component assembly GO:0022607 360 0.039
protein complex assembly GO:0006461 263 0.038
positive regulation of cellular biosynthetic process GO:0031328 295 0.038
chemical homeostasis GO:0048878 292 0.038
cellular component movement GO:0006928 248 0.038
cell motility GO:0048870 202 0.038
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.037
protein phosphorylation GO:0006468 345 0.037
cellular amine metabolic process GO:0044106 38 0.037
cellular response to endogenous stimulus GO:0071495 377 0.036
transmembrane transport GO:0055085 412 0.036
multicellular organismal reproductive process GO:0048609 233 0.036
macromolecular complex subunit organization GO:0043933 339 0.035
proteolysis GO:0006508 175 0.035
cellular homeostasis GO:0019725 252 0.035
positive regulation of developmental process GO:0051094 283 0.035
carboxylic acid metabolic process GO:0019752 289 0.035
rna biosynthetic process GO:0032774 380 0.034
regulation of transcription dna templated GO:0006355 374 0.034
cellular chemical homeostasis GO:0055082 247 0.033
intracellular transport GO:0046907 185 0.033
response to acid chemical GO:0001101 222 0.033
transcription from rna polymerase ii promoter GO:0006366 252 0.033
response to corticosteroid GO:0031960 235 0.032
regulation of catalytic activity GO:0050790 304 0.032
reproduction GO:0000003 245 0.032
regulation of nucleic acid templated transcription GO:1903506 380 0.032
cell cell signaling GO:0007267 335 0.032
regulation of cellular protein metabolic process GO:0032268 267 0.031
regulation of protein phosphorylation GO:0001932 183 0.031
regulation of cellular amine metabolic process GO:0033238 8 0.031
protein complex subunit organization GO:0071822 302 0.031
regulation of hydrolase activity GO:0051336 143 0.031
tissue development GO:0009888 252 0.031
response to nutrient GO:0007584 248 0.031
rna metabolic process GO:0016070 406 0.030
reproductive system development GO:0061458 128 0.029
homeostatic process GO:0042592 331 0.029
programmed cell death GO:0012501 392 0.029
amine metabolic process GO:0009308 38 0.029
lipid metabolic process GO:0006629 283 0.029
positive regulation of gene expression GO:0010628 244 0.029
cellular lipid metabolic process GO:0044255 208 0.028
regulation of multicellular organismal development GO:2000026 376 0.028
response to hypoxia GO:0001666 231 0.028
cell projection organization GO:0030030 302 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
cation transport GO:0006812 382 0.028
blood circulation GO:0008015 183 0.028
regulation of rna biosynthetic process GO:2001141 381 0.027
cellular amino acid metabolic process GO:0006520 107 0.027
regulation of signal transduction GO:0009966 318 0.026
regulation of phosphorylation GO:0042325 248 0.026
carbohydrate derivative metabolic process GO:1901135 346 0.026
positive regulation of cellular component organization GO:0051130 200 0.026
positive regulation of signaling GO:0023056 270 0.026
response to metal ion GO:0010038 253 0.026
localization of cell GO:0051674 202 0.026
regulation of canonical wnt signaling pathway GO:0060828 4 0.026
regulation of secretion GO:0051046 224 0.026
single organism biosynthetic process GO:0044711 342 0.025
negative regulation of metabolic process GO:0009892 331 0.025
regulation of nervous system development GO:0051960 264 0.025
response to peptide hormone GO:0043434 278 0.025
single organism organelle organization GO:1902589 180 0.025
cellular response to acid chemical GO:0071229 75 0.025
reproductive structure development GO:0048608 128 0.025
regulation of immune system process GO:0002682 123 0.025
nucleotide metabolic process GO:0009117 279 0.025
cellular catabolic process GO:0044248 295 0.024
neuron development GO:0048666 286 0.024
response to ketone GO:1901654 182 0.024
regulation of protein modification process GO:0031399 194 0.024
cellular response to organic cyclic compound GO:0071407 202 0.024
central nervous system development GO:0007417 311 0.024
positive regulation of cell proliferation GO:0008284 249 0.024
positive regulation of transport GO:0051050 245 0.024
response to oxygen levels GO:0070482 265 0.024
negative regulation of cellular metabolic process GO:0031324 281 0.024
calcium ion homeostasis GO:0055074 162 0.023
positive regulation of nucleic acid templated transcription GO:1903508 197 0.023
response to glucocorticoid GO:0051384 223 0.023
ion transmembrane transport GO:0034220 365 0.023
negative regulation of gene expression GO:0010629 199 0.023
secretion GO:0046903 307 0.023
response to peptide GO:1901652 292 0.023
cellular ion homeostasis GO:0006873 184 0.023
macromolecular complex assembly GO:0065003 273 0.023
positive regulation of molecular function GO:0044093 230 0.023
protein complex biogenesis GO:0070271 263 0.022
development of primary sexual characteristics GO:0045137 107 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.022
positive regulation of rna metabolic process GO:0051254 203 0.022
cellular response to stress GO:0033554 269 0.022
response to oxidative stress GO:0006979 186 0.022
multi multicellular organism process GO:0044706 138 0.022
rhythmic process GO:0048511 156 0.022
anatomical structure morphogenesis GO:0009653 298 0.022
nitrogen compound transport GO:0071705 229 0.022
neurological system process GO:0050877 219 0.022
regulation of neurogenesis GO:0050767 247 0.021
negative regulation of macromolecule metabolic process GO:0010605 260 0.021
monocarboxylic acid metabolic process GO:0032787 152 0.021
catabolic process GO:0009056 351 0.021
regulation of rna metabolic process GO:0051252 391 0.021
positive regulation of phosphate metabolic process GO:0045937 262 0.021
circulatory system process GO:0003013 183 0.021
cell migration GO:0016477 197 0.021
neuron projection development GO:0031175 273 0.021
transcription dna templated GO:0006351 377 0.021
organophosphate metabolic process GO:0019637 370 0.020
apoptotic process GO:0006915 381 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.020
gland development GO:0048732 155 0.020
positive regulation of catalytic activity GO:0043085 184 0.020
growth GO:0040007 165 0.020
gonad development GO:0008406 104 0.020
anterior posterior pattern specification GO:0009952 1 0.020
locomotion GO:0040011 237 0.020
divalent inorganic cation homeostasis GO:0072507 165 0.020
regulation of cellular localization GO:0060341 263 0.020
regulation of apoptotic process GO:0042981 335 0.020
positive regulation of cell development GO:0010720 176 0.020
ossification GO:0001503 70 0.019
peptidyl amino acid modification GO:0018193 126 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
cellular calcium ion homeostasis GO:0006874 160 0.019
cellular divalent inorganic cation homeostasis GO:0072503 162 0.019
regulation of cell differentiation GO:0045595 320 0.019
positive regulation of cellular amine metabolic process GO:0033240 3 0.019
negative regulation of protein metabolic process GO:0051248 114 0.019
positive regulation of cell communication GO:0010647 271 0.019
regulation of system process GO:0044057 208 0.019
single organism intracellular transport GO:1902582 166 0.019
cation homeostasis GO:0055080 195 0.019
sexual reproduction GO:0019953 148 0.019
regulation of cell motility GO:2000145 131 0.019
positive regulation of cellular protein metabolic process GO:0032270 167 0.019
neuron differentiation GO:0030182 368 0.019
cell adhesion GO:0007155 110 0.019
nucleobase containing small molecule metabolic process GO:0055086 316 0.019
regulation of locomotion GO:0040012 148 0.019
regulation of hormone levels GO:0010817 187 0.019
positive regulation of response to stimulus GO:0048584 285 0.019
negative regulation of cell death GO:0060548 229 0.018
ras protein signal transduction GO:0007265 29 0.018
positive regulation of protein metabolic process GO:0051247 178 0.018
positive regulation of phosphorylation GO:0042327 177 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
regulation of programmed cell death GO:0043067 341 0.018
developmental process involved in reproduction GO:0003006 159 0.018
axis specification GO:0009798 4 0.018
immune system process GO:0002376 204 0.018
positive regulation of transcription dna templated GO:0045893 197 0.018
regulation of cell projection organization GO:0031344 175 0.018
regulation of cell development GO:0060284 263 0.018
regulation of secretion by cell GO:1903530 208 0.018
positive regulation of nervous system development GO:0051962 178 0.018
female pregnancy GO:0007565 122 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
regulation of neuron differentiation GO:0045664 208 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
carbohydrate derivative catabolic process GO:1901136 147 0.017
salivary gland development GO:0007431 3 0.017
positive regulation of protein modification process GO:0031401 142 0.017
cellular response to hormone stimulus GO:0032870 247 0.017
regulation of intracellular signal transduction GO:1902531 218 0.017
brain development GO:0007420 247 0.017
cellular metal ion homeostasis GO:0006875 172 0.017
positive regulation of rna biosynthetic process GO:1902680 197 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.016
response to estradiol GO:0032355 164 0.016
positive regulation of phosphorus metabolic process GO:0010562 262 0.016
cellular cation homeostasis GO:0030003 180 0.016
purine ribonucleoside metabolic process GO:0046128 168 0.016
immune response GO:0006955 104 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.016
lipid biosynthetic process GO:0008610 128 0.016
neuron death GO:0070997 127 0.016
sex differentiation GO:0007548 113 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
purine containing compound metabolic process GO:0072521 253 0.016
head development GO:0060322 247 0.016
gastrulation GO:0007369 2 0.016
aging GO:0007568 241 0.016
ribonucleotide metabolic process GO:0009259 231 0.016
protein oligomerization GO:0051259 191 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.016
embryonic pattern specification GO:0009880 1 0.016
heart morphogenesis GO:0003007 3 0.016
maintenance of location GO:0051235 17 0.016
ribonucleoside metabolic process GO:0009119 174 0.016
protein homooligomerization GO:0051260 91 0.015
regulation of cellular catabolic process GO:0031329 101 0.015
single organism catabolic process GO:0044712 283 0.015
positive regulation of neurogenesis GO:0050769 165 0.015
regulation of cell migration GO:0030334 128 0.015
cell growth GO:0016049 104 0.015
regulation of transferase activity GO:0051338 123 0.015
response to ethanol GO:0045471 162 0.015
metal ion transport GO:0030001 289 0.015
regeneration GO:0031099 163 0.015
cellular response to nitrogen compound GO:1901699 210 0.015
response to estrogen GO:0043627 232 0.015
synaptic transmission GO:0007268 235 0.015
regulation of neuron projection development GO:0010975 161 0.015
male gamete generation GO:0048232 99 0.015
vesicle mediated transport GO:0016192 181 0.015
negative regulation of cell proliferation GO:0008285 119 0.015
response to transition metal nanoparticle GO:1990267 122 0.015
regulation of ion transport GO:0043269 245 0.015
gamete generation GO:0007276 124 0.015
positive regulation of protein phosphorylation GO:0001934 135 0.015
regulation of growth GO:0040008 105 0.015
response to purine containing compound GO:0014074 126 0.015
response to organophosphorus GO:0046683 102 0.014
cytoplasmic transport GO:0016482 115 0.014
sequestering of calcium ion GO:0051208 8 0.014
regulation of cellular component movement GO:0051270 150 0.014
muscle structure development GO:0061061 87 0.014
response to reactive oxygen species GO:0000302 120 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
response to retinoic acid GO:0032526 63 0.014
cation transmembrane transport GO:0098655 263 0.014
ion homeostasis GO:0050801 212 0.014
establishment of tissue polarity GO:0007164 2 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
vascular process in circulatory system GO:0003018 96 0.014
cellular component morphogenesis GO:0032989 155 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
positive regulation of neuron projection development GO:0010976 99 0.014
spermatogenesis GO:0007283 99 0.014
anion transport GO:0006820 178 0.014
response to cytokine GO:0034097 215 0.014
regulation of blood vessel size GO:0050880 89 0.014
epithelium development GO:0060429 96 0.013
positive regulation of cell projection organization GO:0031346 111 0.013
positive regulation of locomotion GO:0040017 102 0.013
metal ion homeostasis GO:0055065 186 0.013
negative regulation of multicellular organismal process GO:0051241 203 0.013
response to biotic stimulus GO:0009607 226 0.013
non canonical wnt signaling pathway GO:0035567 3 0.013
response to vitamin GO:0033273 131 0.013
behavior GO:0007610 205 0.013
purine nucleoside triphosphate catabolic process GO:0009146 122 0.013
response to external biotic stimulus GO:0043207 221 0.013
response to growth factor GO:0070848 189 0.013
negative regulation of molecular function GO:0044092 133 0.013
peptidyl tyrosine phosphorylation GO:0018108 72 0.013
protein processing GO:0016485 68 0.013
heterocycle catabolic process GO:0046700 167 0.013
developmental growth GO:0048589 100 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
regulation of establishment of planar polarity GO:0090175 2 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
response to other organism GO:0051707 220 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
liver development GO:0001889 90 0.013
negative regulation of transport GO:0051051 136 0.013
circadian rhythm GO:0007623 88 0.013
nucleoside catabolic process GO:0009164 126 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
nucleoside metabolic process GO:0009116 179 0.013
positive regulation of cell migration GO:0030335 96 0.012
response to wounding GO:0009611 254 0.012
response to camp GO:0051591 91 0.012
negative regulation of cell communication GO:0010648 158 0.012
regulation of anatomical structure size GO:0090066 135 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
purine containing compound catabolic process GO:0072523 138 0.012
gliogenesis GO:0042063 93 0.012
actin filament based process GO:0030029 86 0.012
neural crest cell differentiation GO:0014033 2 0.012
nucleotide catabolic process GO:0009166 139 0.012
positive regulation of ion transport GO:0043270 94 0.012
tube development GO:0035295 89 0.012
regulation of membrane potential GO:0042391 110 0.012
regulation of neuron death GO:1901214 115 0.012
hepaticobiliary system development GO:0061008 90 0.012
sequestering of metal ion GO:0051238 9 0.012
regulation of synaptic transmission GO:0050804 141 0.012
hematopoietic progenitor cell differentiation GO:0002244 2 0.012
regulation of kinase activity GO:0043549 117 0.012
lipid localization GO:0010876 62 0.012
lipid storage GO:0019915 1 0.012
appendage morphogenesis GO:0035107 4 0.012
cell morphogenesis GO:0000902 142 0.012
negative regulation of signaling GO:0023057 157 0.012
biological adhesion GO:0022610 110 0.012
defense response GO:0006952 194 0.012
rho protein signal transduction GO:0007266 11 0.012
regulation of vesicle mediated transport GO:0060627 81 0.012
regulation of response to stress GO:0080134 126 0.012
inorganic ion transmembrane transport GO:0098660 229 0.012
negative regulation of cell cycle phase transition GO:1901988 4 0.012
positive regulation of signal transduction GO:0009967 175 0.012
response to amino acid GO:0043200 75 0.012
negative regulation of phosphate metabolic process GO:0045936 80 0.012
response to toxic substance GO:0009636 133 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
response to carbohydrate GO:0009743 183 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
regulation of proteolysis GO:0030162 66 0.011
cellular response to retinoic acid GO:0071300 27 0.011
cell part morphogenesis GO:0032990 123 0.011
cellular response to external stimulus GO:0071496 118 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
organophosphate catabolic process GO:0046434 148 0.011
positive regulation of cell motility GO:2000147 97 0.011
g protein coupled receptor signaling pathway GO:0007186 242 0.011
cell type specific apoptotic process GO:0097285 134 0.011
macromolecule localization GO:0033036 252 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
cellular response to oxidative stress GO:0034599 76 0.011
cell cycle GO:0007049 101 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
chromosome segregation GO:0007059 2 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
eye morphogenesis GO:0048592 4 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
regulation of protein kinase activity GO:0045859 105 0.011
organic substance catabolic process GO:1901575 316 0.011
secretion by cell GO:0032940 248 0.011
purine ribonucleoside catabolic process GO:0046130 124 0.011
cell cycle checkpoint GO:0000075 2 0.011
response to calcium ion GO:0051592 59 0.011
nucleoside triphosphate catabolic process GO:0009143 123 0.011
wound healing GO:0042060 122 0.011
regulation of body fluid levels GO:0050878 90 0.011
organic acid transport GO:0015849 116 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
urogenital system development GO:0001655 78 0.011
multicellular organism growth GO:0035264 1 0.011
small molecule biosynthetic process GO:0044283 124 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
positive regulation of immune system process GO:0002684 90 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.010
response to bacterium GO:0009617 200 0.010
cardiac chamber development GO:0003205 1 0.010
cellular response to reactive oxygen species GO:0034614 55 0.010
positive regulation of growth GO:0045927 55 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.010
regulation of cell growth GO:0001558 85 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
regulation of ion transmembrane transport GO:0034765 121 0.010
kidney development GO:0001822 67 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.010
organonitrogen compound biosynthetic process GO:1901566 167 0.010
cellular response to steroid hormone stimulus GO:0071383 93 0.010
response to glucose GO:0009749 136 0.010
negative regulation of response to stimulus GO:0048585 155 0.010
regulation of tube size GO:0035150 89 0.010
establishment of planar polarity GO:0001736 1 0.010
purine nucleoside triphosphate metabolic process GO:0009144 141 0.010
vasoconstriction GO:0042310 54 0.010
response to hydrogen peroxide GO:0042542 89 0.010

Pof1b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.026
sensory system disease DOID:0050155 0 0.024
musculoskeletal system disease DOID:17 0 0.013
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013
disease of metabolism DOID:0014667 0 0.011