Rattus norvegicus

0 known processes

Adap1

ArfGAP with dual PH domains 1

(Aliases: p42IP4,Centa1)

Adap1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
synaptic growth at neuromuscular junction GO:0051124 1 0.449
behavior GO:0007610 205 0.408
regulation of anatomical structure size GO:0090066 135 0.354
cognition GO:0050890 92 0.198
response to inorganic substance GO:0010035 377 0.184
positive regulation of multicellular organismal process GO:0051240 387 0.175
regulation of ion transport GO:0043269 245 0.151
vascular process in circulatory system GO:0003018 96 0.149
regulation of nervous system development GO:0051960 264 0.146
carboxylic acid metabolic process GO:0019752 289 0.140
positive regulation of signaling GO:0023056 270 0.139
regulation of blood vessel size GO:0050880 89 0.135
synaptic transmission GO:0007268 235 0.132
oxoacid metabolic process GO:0043436 290 0.130
response to metal ion GO:0010038 253 0.127
organic acid metabolic process GO:0006082 292 0.119
positive regulation of cell communication GO:0010647 271 0.111
learning or memory GO:0007611 90 0.108
single organism behavior GO:0044708 130 0.108
regulation of synaptic vesicle endocytosis GO:1900242 1 0.107
programmed cell death GO:0012501 392 0.096
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.094
neuron death GO:0070997 127 0.094
establishment of organelle localization GO:0051656 37 0.093
signal release GO:0023061 145 0.092
regulation of neuron apoptotic process GO:0043523 83 0.092
aging GO:0007568 241 0.092
regulation of neuron death GO:1901214 115 0.089
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.087
synaptic vesicle exocytosis GO:0016079 15 0.087
cell projection morphogenesis GO:0048858 123 0.085
establishment of vesicle localization GO:0051650 31 0.084
regulation of phosphate metabolic process GO:0019220 349 0.083
regulation of cell differentiation GO:0045595 320 0.081
organic substance catabolic process GO:1901575 316 0.080
head development GO:0060322 247 0.080
neurotransmitter secretion GO:0007269 33 0.079
regulation of synapse assembly GO:0051963 15 0.078
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.078
positive regulation of synaptic vesicle recycling GO:1903423 1 0.076
positive regulation of nervous system development GO:0051962 178 0.075
negative regulation of programmed cell death GO:0043069 183 0.075
circulatory system process GO:0003013 183 0.075
synapse assembly GO:0007416 29 0.074
central nervous system development GO:0007417 311 0.074
regulation of cellular component organization GO:0051128 368 0.073
membrane organization GO:0061024 94 0.070
blood circulation GO:0008015 183 0.069
locomotion GO:0040011 237 0.068
positive regulation of molecular function GO:0044093 230 0.064
regulation of locomotion GO:0040012 148 0.064
organophosphate metabolic process GO:0019637 370 0.064
gliogenesis GO:0042063 93 0.063
cellular component biogenesis GO:0044085 368 0.062
regulation of phosphorus metabolic process GO:0051174 349 0.058
regulation of neurogenesis GO:0050767 247 0.057
anion transport GO:0006820 178 0.057
secretion GO:0046903 307 0.056
cytosolic calcium ion homeostasis GO:0051480 140 0.055
ribonucleotide metabolic process GO:0009259 231 0.055
regulation of secretion GO:0051046 224 0.055
regulation of molecular function GO:0065009 398 0.055
synapse organization GO:0050808 46 0.054
regulation of tube size GO:0035150 89 0.054
cell cell signaling GO:0007267 335 0.053
neuron projection morphogenesis GO:0048812 122 0.053
regulation of anion transport GO:0044070 43 0.052
regulation of neuron projection development GO:0010975 161 0.051
catabolic process GO:0009056 351 0.051
regulation of growth GO:0040008 105 0.051
organelle localization GO:0051640 55 0.050
purine nucleotide biosynthetic process GO:0006164 83 0.050
cellular amino acid metabolic process GO:0006520 107 0.050
epithelium development GO:0060429 96 0.049
purine containing compound metabolic process GO:0072521 253 0.049
negative regulation of metabolic process GO:0009892 331 0.048
learning GO:0007612 33 0.048
cellular ketone metabolic process GO:0042180 51 0.047
synaptic vesicle endocytosis GO:0048488 4 0.047
regulation of synapse structure and activity GO:0050803 21 0.046
reproductive process GO:0022414 372 0.046
purine containing compound biosynthetic process GO:0072522 85 0.046
brain development GO:0007420 247 0.046
regulation of cellular protein metabolic process GO:0032268 267 0.046
nucleotide metabolic process GO:0009117 279 0.045
regulated secretory pathway GO:0045055 17 0.045
regulation of cellular amine metabolic process GO:0033238 8 0.045
negative regulation of cellular metabolic process GO:0031324 281 0.044
regulation of multicellular organismal development GO:2000026 376 0.044
exocytosis GO:0006887 60 0.043
positive regulation of phosphorus metabolic process GO:0010562 262 0.043
cell type specific apoptotic process GO:0097285 134 0.043
neurotransmitter transport GO:0006836 42 0.043
cellular component morphogenesis GO:0032989 155 0.042
cell part morphogenesis GO:0032990 123 0.041
positive regulation of transport GO:0051050 245 0.041
positive regulation of developmental process GO:0051094 283 0.041
synaptic vesicle localization GO:0097479 24 0.041
multicellular organismal reproductive process GO:0048609 233 0.040
neurological system process GO:0050877 219 0.040
amine metabolic process GO:0009308 38 0.039
response to nutrient levels GO:0031667 370 0.039
dna metabolic process GO:0006259 96 0.039
regulation of cellular localization GO:0060341 263 0.038
neuron projection development GO:0031175 273 0.038
axonogenesis GO:0007409 71 0.038
nitrogen compound transport GO:0071705 229 0.038
dendrite morphogenesis GO:0048813 43 0.037
rhythmic synaptic transmission GO:0060024 1 0.037
positive regulation of secretion GO:0051047 140 0.037
adult locomotory behavior GO:0008344 4 0.036
cellular catabolic process GO:0044248 295 0.036
cellular homeostasis GO:0019725 252 0.036
synaptic vesicle transport GO:0048489 23 0.036
neuron apoptotic process GO:0051402 88 0.036
positive regulation of secretion by cell GO:1903532 128 0.036
regulation of peptide transport GO:0090087 87 0.036
cellular nitrogen compound catabolic process GO:0044270 163 0.035
neuromuscular process GO:0050905 2 0.035
cellular component assembly GO:0022607 360 0.035
sensory perception GO:0007600 101 0.035
negative regulation of cell communication GO:0010648 158 0.035
protein complex assembly GO:0006461 263 0.034
positive regulation of synaptic transmission GO:0050806 62 0.034
organic cyclic compound catabolic process GO:1901361 175 0.034
regulation of protein kinase activity GO:0045859 105 0.033
dephosphorylation GO:0016311 98 0.033
g protein coupled receptor signaling pathway GO:0007186 242 0.033
negative regulation of signal transduction GO:0009968 83 0.033
regulation of signal transduction GO:0009966 318 0.033
regulation of synapse organization GO:0050807 19 0.033
regulation of hydrolase activity GO:0051336 143 0.032
regulation of synaptic transmission GO:0050804 141 0.032
response to insulin GO:0032868 133 0.032
positive regulation of neurogenesis GO:0050769 165 0.032
regulation of cell projection organization GO:0031344 175 0.032
alpha amino 3 hydroxy 5 methyl 4 isoxazole propionate selective glutamate receptor clustering GO:0097113 2 0.032
response to nutrient GO:0007584 248 0.032
vesicle localization GO:0051648 33 0.031
ion homeostasis GO:0050801 212 0.031
regulation of blood pressure GO:0008217 83 0.030
glial cell differentiation GO:0010001 65 0.030
neuron differentiation GO:0030182 368 0.030
regulation of secretion by cell GO:1903530 208 0.030
organonitrogen compound biosynthetic process GO:1901566 167 0.030
regulation of rna biosynthetic process GO:2001141 381 0.030
regulation of neurotransmitter levels GO:0001505 42 0.029
regulation of g protein coupled receptor protein signaling pathway GO:0008277 28 0.029
negative regulation of response to stimulus GO:0048585 155 0.028
dendrite development GO:0016358 72 0.028
regulation of axon extension GO:0030516 24 0.028
transcription dna templated GO:0006351 377 0.028
cellular cation homeostasis GO:0030003 180 0.028
neuron development GO:0048666 286 0.028
nucleoside phosphate metabolic process GO:0006753 283 0.028
response to zinc ion GO:0010043 39 0.028
cation homeostasis GO:0055080 195 0.027
growth GO:0040007 165 0.027
regulation of cellular amino acid metabolic process GO:0006521 2 0.027
regulation of cellular ketone metabolic process GO:0010565 27 0.027
vesicle mediated transport GO:0016192 181 0.027
intracellular transport GO:0046907 185 0.027
negative regulation of signaling GO:0023057 157 0.026
multicellular organism reproduction GO:0032504 233 0.026
negative regulation of neuron death GO:1901215 69 0.026
regulation of cellular component size GO:0032535 51 0.026
negative regulation of phosphorus metabolic process GO:0010563 80 0.026
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 3 0.026
cellular response to oxygen containing compound GO:1901701 386 0.025
locomotory exploration behavior GO:0035641 1 0.025
negative regulation of catalytic activity GO:0043086 103 0.025
reproduction GO:0000003 245 0.025
negative regulation of protein metabolic process GO:0051248 114 0.025
response to radiation GO:0009314 137 0.024
negative regulation of cell death GO:0060548 229 0.024
positive regulation of cellular amine metabolic process GO:0033240 3 0.024
positive regulation of cell differentiation GO:0045597 217 0.024
ionotropic glutamate receptor signaling pathway GO:0035235 34 0.024
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.024
homeostatic process GO:0042592 331 0.024
epidermal growth factor receptor signaling pathway GO:0007173 23 0.024
protein phosphorylation GO:0006468 345 0.024
negative regulation of cellular component organization GO:0051129 83 0.024
chemotaxis GO:0006935 66 0.024
cellular response to stress GO:0033554 269 0.024
multi organism reproductive process GO:0044703 262 0.024
single organism biosynthetic process GO:0044711 342 0.023
regulation of catalytic activity GO:0050790 304 0.023
regulation of neuron differentiation GO:0045664 208 0.023
neuron projection guidance GO:0097485 24 0.023
phosphatidylinositol dephosphorylation GO:0046856 4 0.023
regulation of ion transmembrane transport GO:0034765 121 0.023
protein complex biogenesis GO:0070271 263 0.023
cellular metal ion homeostasis GO:0006875 172 0.023
carbohydrate derivative metabolic process GO:1901135 346 0.022
regulation of phosphatidylinositol dephosphorylation GO:0060304 1 0.022
defecation GO:0030421 1 0.022
defense response GO:0006952 194 0.022
carbohydrate metabolic process GO:0005975 130 0.022
macromolecular complex assembly GO:0065003 273 0.022
ribose phosphate metabolic process GO:0019693 235 0.022
response to toxic substance GO:0009636 133 0.022
regulation of lyase activity GO:0051339 22 0.021
aromatic compound catabolic process GO:0019439 168 0.021
positive regulation of cellular component biogenesis GO:0044089 55 0.021
regulation of organelle organization GO:0033043 80 0.021
divalent inorganic cation transport GO:0072511 134 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.021
negative regulation of secretion GO:0051048 82 0.021
response to cytokine GO:0034097 215 0.021
negative regulation of neuron differentiation GO:0045665 62 0.020
single organism membrane organization GO:0044802 74 0.020
cellular response to growth factor stimulus GO:0071363 162 0.020
rna metabolic process GO:0016070 406 0.020
cation transport GO:0006812 382 0.020
negative regulation of apoptotic process GO:0043066 181 0.020
long term synaptic potentiation GO:0060291 21 0.020
axon development GO:0061564 96 0.020
multicellular organism growth GO:0035264 1 0.020
presynaptic membrane assembly GO:0097105 3 0.019
purine nucleotide metabolic process GO:0006163 229 0.019
response to transition metal nanoparticle GO:1990267 122 0.019
positive regulation of immune system process GO:0002684 90 0.019
regulation of nucleic acid templated transcription GO:1903506 380 0.019
amino acid transport GO:0006865 70 0.019
cell projection organization GO:0030030 302 0.019
regulation of cell development GO:0060284 263 0.019
cellular amine metabolic process GO:0044106 38 0.019
regulation of metal ion transport GO:0010959 118 0.019
cellular response to abiotic stimulus GO:0071214 85 0.019
regulation of amino acid transport GO:0051955 25 0.019
regulation of peptide hormone secretion GO:0090276 80 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.019
carboxylic acid transport GO:0046942 115 0.018
immune response GO:0006955 104 0.018
memory GO:0007613 54 0.018
cellular calcium ion homeostasis GO:0006874 160 0.018
regulation of synaptic vesicle exocytosis GO:2000300 6 0.018
regulation of nucleotide metabolic process GO:0006140 117 0.018
positive regulation of signal transduction GO:0009967 175 0.018
sensory perception of pain GO:0019233 73 0.018
cyclic nucleotide metabolic process GO:0009187 80 0.018
hormone secretion GO:0046879 115 0.018
regulation of protein metabolic process GO:0051246 289 0.018
cellular response to external stimulus GO:0071496 118 0.018
single organism organelle organization GO:1902589 180 0.018
regulation of hormone levels GO:0010817 187 0.018
hormone metabolic process GO:0042445 69 0.018
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
negative regulation of transport GO:0051051 136 0.017
peptide transport GO:0015833 97 0.017
response to peptide GO:1901652 292 0.017
macromolecular complex subunit organization GO:0043933 339 0.017
response to alkaloid GO:0043279 132 0.017
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 4 0.017
intracellular signal transduction GO:0035556 314 0.017
nucleobase containing small molecule metabolic process GO:0055086 316 0.017
regulation of fat cell differentiation GO:0045598 3 0.017
response to carbohydrate GO:0009743 183 0.017
adenosine receptor signaling pathway GO:0001973 7 0.017
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.017
regulation of apoptotic process GO:0042981 335 0.017
negative regulation of secretion by cell GO:1903531 72 0.017
positive regulation of cell development GO:0010720 176 0.016
response to hydrogen peroxide GO:0042542 89 0.016
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 5 0.016
positive regulation of phosphate metabolic process GO:0045937 262 0.016
spindle organization GO:0007051 2 0.016
calcium ion homeostasis GO:0055074 162 0.016
protein localization GO:0008104 191 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.016
regulation of cell growth GO:0001558 85 0.016
regulation of blood circulation GO:1903522 110 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
negative regulation of phosphate metabolic process GO:0045936 80 0.016
regulation of cellular carbohydrate metabolic process GO:0010675 39 0.016
epithelial cell differentiation GO:0030855 71 0.016
cation transmembrane transport GO:0098655 263 0.016
postsynaptic density protein 95 clustering GO:0097119 2 0.016
metal ion transport GO:0030001 289 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
regulation of rna metabolic process GO:0051252 391 0.016
regulation of axonogenesis GO:0050770 37 0.015
negative regulation of macromolecule metabolic process GO:0010605 260 0.015
protein complex subunit organization GO:0071822 302 0.015
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.015
negative regulation of cellular protein metabolic process GO:0032269 106 0.015
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.015
sexual reproduction GO:0019953 148 0.015
localization of cell GO:0051674 202 0.015
regulation of immune system process GO:0002682 123 0.015
regulation of calcium ion transport GO:0051924 77 0.015
salivary gland development GO:0007431 3 0.015
amide transport GO:0042886 105 0.015
regulation of exocytosis GO:0017157 37 0.015
rna biosynthetic process GO:0032774 380 0.015
g protein coupled purinergic receptor signaling pathway GO:0035588 8 0.015
cell growth GO:0016049 104 0.014
cytoplasmic transport GO:0016482 115 0.014
carbohydrate derivative biosynthetic process GO:1901137 124 0.014
developmental growth GO:0048589 100 0.014
organonitrogen compound catabolic process GO:1901565 179 0.014
gastrulation GO:0007369 2 0.014
regulation of hormone secretion GO:0046883 106 0.014
membrane fusion GO:0061025 26 0.014
nucleic acid templated transcription GO:0097659 379 0.014
regulation of cell motility GO:2000145 131 0.014
response to axon injury GO:0048678 59 0.014
negative regulation of nervous system development GO:0051961 79 0.014
single organism catabolic process GO:0044712 283 0.014
calcium ion transport GO:0006816 131 0.014
response to electrical stimulus GO:0051602 56 0.014
peptidyl tyrosine autophosphorylation GO:0038083 1 0.014
positive regulation of protein metabolic process GO:0051247 178 0.014
circadian rhythm GO:0007623 88 0.014
cerebellar cortex formation GO:0021697 2 0.014
lipid metabolic process GO:0006629 283 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.013
gamma aminobutyric acid secretion GO:0014051 6 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
cerebellar granule cell precursor proliferation GO:0021930 1 0.013
regulation of programmed cell death GO:0043067 341 0.013
positive regulation of cell death GO:0010942 184 0.013
nucleotide catabolic process GO:0009166 139 0.013
regulation of extent of cell growth GO:0061387 25 0.013
cellular response to extracellular stimulus GO:0031668 73 0.013
positive regulation of response to stimulus GO:0048584 285 0.013
regulation of transferase activity GO:0051338 123 0.013
nucleoside phosphate biosynthetic process GO:1901293 102 0.013
regulation of notch signaling pathway GO:0008593 3 0.013
cellular response to acid chemical GO:0071229 75 0.013
apoptotic signaling pathway GO:0097190 27 0.013
regulation of membrane potential GO:0042391 110 0.013
regulation of respiratory gaseous exchange by neurological system process GO:0002087 1 0.013
negative regulation of innate immune response GO:0045824 4 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
regulation of phosphorylation GO:0042325 248 0.013
neuron recognition GO:0008038 9 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
cerebellar purkinje cell layer morphogenesis GO:0021692 1 0.013
vesicle organization GO:0016050 29 0.013
endoplasmic reticulum organization GO:0007029 1 0.013
positive regulation of biosynthetic process GO:0009891 319 0.013
organic anion transport GO:0015711 132 0.013
positive regulation of neuron apoptotic process GO:0043525 33 0.013
positive regulation of programmed cell death GO:0043068 157 0.013
axon extension GO:0048675 26 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
regulation of peptide secretion GO:0002791 82 0.012
response to extracellular stimulus GO:0009991 380 0.012
developmental growth involved in morphogenesis GO:0060560 33 0.012
leukocyte activation GO:0045321 76 0.012
nucleoside metabolic process GO:0009116 179 0.012
cell morphogenesis GO:0000902 142 0.012
organelle organization GO:0006996 266 0.012
regulation of response to external stimulus GO:0032101 106 0.012
regulation of catabolic process GO:0009894 113 0.012
axon guidance GO:0007411 24 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
cellular protein localization GO:0034613 122 0.012
regulation of transmembrane transport GO:0034762 122 0.012
ion transmembrane transport GO:0034220 365 0.012
regulation of dendrite development GO:0050773 59 0.012
response to corticosterone GO:0051412 40 0.012
response to ketone GO:1901654 182 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
small molecule biosynthetic process GO:0044283 124 0.012
peptidyl tyrosine phosphorylation GO:0018108 72 0.012
sequestering of calcium ion GO:0051208 8 0.012
calcium ion dependent exocytosis GO:0017156 16 0.012
negative regulation of molecular function GO:0044092 133 0.012
secretion by cell GO:0032940 248 0.011
locomotory behavior GO:0007626 15 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
chemical homeostasis GO:0048878 292 0.011
telencephalon development GO:0021537 62 0.011
regulation of establishment of protein localization GO:0070201 69 0.011
single organism reproductive process GO:0044702 297 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
positive regulation of cellular biosynthetic process GO:0031328 295 0.011
negative regulation of signal transduction in absence of ligand GO:1901099 3 0.011
regulation of insulin secretion GO:0050796 65 0.011
positive regulation of hydrolase activity GO:0051345 86 0.011
axis specification GO:0009798 4 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
regulation of vasoconstriction GO:0019229 44 0.011
regulation of system process GO:0044057 208 0.011
actin filament based process GO:0030029 86 0.011
cellular component movement GO:0006928 248 0.011
actin filament organization GO:0007015 42 0.011
interleukin 18 production GO:0032621 1 0.011
regulation of neuronal synaptic plasticity GO:0048168 31 0.011
oligodendrocyte differentiation GO:0048709 32 0.011
positive regulation of fat cell differentiation GO:0045600 2 0.011
associative learning GO:0008306 19 0.011
peptide hormone secretion GO:0030072 84 0.011
positive regulation of blood circulation GO:1903524 65 0.011
cell proliferation in hindbrain GO:0021534 2 0.011
organophosphate catabolic process GO:0046434 148 0.011
neuron projection extension GO:1990138 26 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
response to light stimulus GO:0009416 52 0.011
regulation of defecation GO:2000292 1 0.011
gamete generation GO:0007276 124 0.011
positive regulation of cell proliferation GO:0008284 249 0.011
regulation of vesicle mediated transport GO:0060627 81 0.011
cyclic nucleotide biosynthetic process GO:0009190 63 0.010
cellular macromolecule localization GO:0070727 122 0.010
negative regulation of cellular biosynthetic process GO:0031327 161 0.010
positive regulation of synaptic vesicle endocytosis GO:1900244 1 0.010
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 31 0.010
response to hexose GO:0009746 144 0.010
response to growth factor GO:0070848 189 0.010
regulation of nucleotide biosynthetic process GO:0030808 47 0.010
embryonic pattern specification GO:0009880 1 0.010
cerebellar purkinje cell layer development GO:0021680 2 0.010
erbb signaling pathway GO:0038127 23 0.010
detection of stimulus GO:0051606 24 0.010
cellular chemical homeostasis GO:0055082 247 0.010
response to molecule of fungal origin GO:0002238 3 0.010
regulation of cellular component biogenesis GO:0044087 86 0.010

Adap1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 0 0.019
disease of anatomical entity DOID:7 0 0.019
nervous system disease DOID:863 0 0.019