Rattus norvegicus

0 known processes

Comtd1

catechol-O-methyltransferase domain containing 1

Comtd1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 292 0.093
oxoacid metabolic process GO:0043436 290 0.078
response to peptide hormone GO:0043434 278 0.073
carboxylic acid metabolic process GO:0019752 289 0.071
brain development GO:0007420 247 0.067
response to peptide GO:1901652 292 0.059
regulation of molecular function GO:0065009 398 0.057
response to nutrient levels GO:0031667 370 0.051
nucleobase containing small molecule metabolic process GO:0055086 316 0.050
response to ketone GO:1901654 182 0.050
regulation of programmed cell death GO:0043067 341 0.049
response to extracellular stimulus GO:0009991 380 0.045
reproductive process GO:0022414 372 0.045
response to estrogen GO:0043627 232 0.045
response to inorganic substance GO:0010035 377 0.044
cell motility GO:0048870 202 0.042
apoptotic process GO:0006915 381 0.040
positive regulation of cell death GO:0010942 184 0.040
response to external biotic stimulus GO:0043207 221 0.040
head development GO:0060322 247 0.040
lipid biosynthetic process GO:0008610 128 0.039
ion transmembrane transport GO:0034220 365 0.038
intracellular signal transduction GO:0035556 314 0.038
response to corticosteroid GO:0031960 235 0.037
cellular ketone metabolic process GO:0042180 51 0.037
negative regulation of metabolic process GO:0009892 331 0.036
response to wounding GO:0009611 254 0.036
response to oxygen levels GO:0070482 265 0.036
response to glucocorticoid GO:0051384 223 0.036
response to metal ion GO:0010038 253 0.035
regulation of cell proliferation GO:0042127 359 0.035
regulation of catalytic activity GO:0050790 304 0.035
carbohydrate derivative metabolic process GO:1901135 346 0.034
cellular response to stress GO:0033554 269 0.034
cellular response to endogenous stimulus GO:0071495 377 0.034
single organism biosynthetic process GO:0044711 342 0.034
organic substance catabolic process GO:1901575 316 0.034
cellular response to nitrogen compound GO:1901699 210 0.034
response to biotic stimulus GO:0009607 226 0.033
cellular amino acid metabolic process GO:0006520 107 0.033
response to decreased oxygen levels GO:0036293 237 0.033
central nervous system development GO:0007417 311 0.033
single organism reproductive process GO:0044702 297 0.032
carboxylic acid biosynthetic process GO:0046394 83 0.032
transmembrane transport GO:0055085 412 0.032
cellular component movement GO:0006928 248 0.031
programmed cell death GO:0012501 392 0.031
positive regulation of cell proliferation GO:0008284 249 0.031
protein complex assembly GO:0006461 263 0.031
regeneration GO:0031099 163 0.031
single organism catabolic process GO:0044712 283 0.030
regulation of cellular protein metabolic process GO:0032268 267 0.030
carbohydrate metabolic process GO:0005975 130 0.030
protein oligomerization GO:0051259 191 0.030
small molecule biosynthetic process GO:0044283 124 0.029
cell cell signaling GO:0007267 335 0.029
protein phosphorylation GO:0006468 345 0.028
catabolic process GO:0009056 351 0.028
response to nutrient GO:0007584 248 0.027
response to oxidative stress GO:0006979 186 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.026
nucleotide metabolic process GO:0009117 279 0.026
organophosphate metabolic process GO:0019637 370 0.026
lipid metabolic process GO:0006629 283 0.026
cellular component assembly GO:0022607 360 0.026
macromolecular complex assembly GO:0065003 273 0.026
localization of cell GO:0051674 202 0.026
neuron differentiation GO:0030182 368 0.025
regulation of phosphorus metabolic process GO:0051174 349 0.025
regulation of cellular ketone metabolic process GO:0010565 27 0.025
cell migration GO:0016477 197 0.025
aging GO:0007568 241 0.025
cellular response to oxygen containing compound GO:1901701 386 0.025
response to carbohydrate GO:0009743 183 0.024
amine metabolic process GO:0009308 38 0.024
cellular amine metabolic process GO:0044106 38 0.024
protein complex biogenesis GO:0070271 263 0.024
response to lipopolysaccharide GO:0032496 191 0.024
positive regulation of cellular biosynthetic process GO:0031328 295 0.024
regulation of nervous system development GO:0051960 264 0.023
cellular response to organonitrogen compound GO:0071417 197 0.023
response to toxic substance GO:0009636 133 0.023
organonitrogen compound biosynthetic process GO:1901566 167 0.023
anatomical structure morphogenesis GO:0009653 298 0.023
cell projection organization GO:0030030 302 0.023
blood circulation GO:0008015 183 0.023
cofactor metabolic process GO:0051186 95 0.023
inorganic ion transmembrane transport GO:0098660 229 0.023
cation transport GO:0006812 382 0.023
cellular response to hormone stimulus GO:0032870 247 0.023
positive regulation of programmed cell death GO:0043068 157 0.022
single organism carbohydrate metabolic process GO:0044723 118 0.022
cellular component biogenesis GO:0044085 368 0.022
homeostatic process GO:0042592 331 0.022
gland development GO:0048732 155 0.022
regulation of apoptotic process GO:0042981 335 0.022
locomotion GO:0040011 237 0.021
protein complex subunit organization GO:0071822 302 0.021
multicellular organismal reproductive process GO:0048609 233 0.021
regulation of phosphate metabolic process GO:0019220 349 0.021
regulation of protein metabolic process GO:0051246 289 0.021
cellular catabolic process GO:0044248 295 0.021
monocarboxylic acid metabolic process GO:0032787 152 0.021
multi organism reproductive process GO:0044703 262 0.021
coenzyme metabolic process GO:0006732 86 0.021
secretion GO:0046903 307 0.021
cellular lipid metabolic process GO:0044255 208 0.020
metal ion transport GO:0030001 289 0.020
regulation of multicellular organismal development GO:2000026 376 0.020
positive regulation of signaling GO:0023056 270 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
regulation of hormone levels GO:0010817 187 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
response to estradiol GO:0032355 164 0.020
regulation of locomotion GO:0040012 148 0.019
response to radiation GO:0009314 137 0.019
negative regulation of macromolecule metabolic process GO:0010605 260 0.019
macromolecular complex subunit organization GO:0043933 339 0.019
nucleoside phosphate metabolic process GO:0006753 283 0.019
defense response GO:0006952 194 0.019
secretion by cell GO:0032940 248 0.019
neuron projection development GO:0031175 273 0.019
oxidation reduction process GO:0055114 304 0.019
neuron development GO:0048666 286 0.019
response to alkaloid GO:0043279 132 0.019
chemical homeostasis GO:0048878 292 0.019
negative regulation of molecular function GO:0044092 133 0.019
protein localization GO:0008104 191 0.018
negative regulation of cellular metabolic process GO:0031324 281 0.018
single organism carbohydrate catabolic process GO:0044724 40 0.018
positive regulation of apoptotic process GO:0043065 154 0.018
fatty acid metabolic process GO:0006631 99 0.018
response to insulin GO:0032868 133 0.018
ion homeostasis GO:0050801 212 0.018
circulatory system development GO:0072359 134 0.018
developmental process involved in reproduction GO:0003006 159 0.017
response to growth factor GO:0070848 189 0.017
positive regulation of biosynthetic process GO:0009891 319 0.017
regulation of secretion GO:0051046 224 0.017
circulatory system process GO:0003013 183 0.017
rna metabolic process GO:0016070 406 0.017
reproduction GO:0000003 245 0.017
response to other organism GO:0051707 220 0.017
response to reactive oxygen species GO:0000302 120 0.017
ribose phosphate metabolic process GO:0019693 235 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
multicellular organism reproduction GO:0032504 233 0.017
dephosphorylation GO:0016311 98 0.017
regulation of protein modification process GO:0031399 194 0.017
organic acid biosynthetic process GO:0016053 83 0.017
regulation of signal transduction GO:0009966 318 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.017
negative regulation of catalytic activity GO:0043086 103 0.017
regulation of cell migration GO:0030334 128 0.016
organic cyclic compound catabolic process GO:1901361 175 0.016
female pregnancy GO:0007565 122 0.016
negative regulation of cell proliferation GO:0008285 119 0.016
cation transmembrane transport GO:0098655 263 0.016
regulation of intracellular signal transduction GO:1902531 218 0.016
macromolecule localization GO:0033036 252 0.016
inorganic cation transmembrane transport GO:0098662 202 0.016
response to acid chemical GO:0001101 222 0.016
regulation of cell motility GO:2000145 131 0.016
tissue development GO:0009888 252 0.016
regulation of cell differentiation GO:0045595 320 0.016
response to cytokine GO:0034097 215 0.016
behavior GO:0007610 205 0.015
cellular response to lipid GO:0071396 201 0.015
positive regulation of cell communication GO:0010647 271 0.015
cellular chemical homeostasis GO:0055082 247 0.015
negative regulation of multicellular organismal process GO:0051241 203 0.015
response to ethanol GO:0045471 162 0.015
protein transport GO:0015031 132 0.015
response to bacterium GO:0009617 200 0.015
dna metabolic process GO:0006259 96 0.015
intracellular protein transport GO:0006886 79 0.015
regulation of hydrolase activity GO:0051336 143 0.015
signal transduction by phosphorylation GO:0023014 144 0.015
response to purine containing compound GO:0014074 126 0.015
negative regulation of cell death GO:0060548 229 0.015
positive regulation of molecular function GO:0044093 230 0.014
sexual reproduction GO:0019953 148 0.014
organic hydroxy compound metabolic process GO:1901615 115 0.014
regulation of neurogenesis GO:0050767 247 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
regulation of cellular component organization GO:0051128 368 0.013
vasculature development GO:0001944 70 0.013
nitrogen compound transport GO:0071705 229 0.013
signal release GO:0023061 145 0.013
reproductive system development GO:0061458 128 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
nucleic acid templated transcription GO:0097659 379 0.013
establishment of protein localization GO:0045184 141 0.013
regulation of system process GO:0044057 208 0.013
proteolysis GO:0006508 175 0.013
cellular macromolecule localization GO:0070727 122 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
membrane organization GO:0061024 94 0.013
epithelium development GO:0060429 96 0.013
regulation of secretion by cell GO:1903530 208 0.013
positive regulation of cellular component organization GO:0051130 200 0.013
neurological system process GO:0050877 219 0.013
positive regulation of signal transduction GO:0009967 175 0.013
positive regulation of response to stimulus GO:0048584 285 0.013
response to transition metal nanoparticle GO:1990267 122 0.012
regulation of membrane potential GO:0042391 110 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
positive regulation of transport GO:0051050 245 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
positive regulation of multicellular organismal process GO:0051240 387 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.012
regulation of anatomical structure size GO:0090066 135 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
regulation of cellular component movement GO:0051270 150 0.012
protein homooligomerization GO:0051260 91 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
cellular response to peptide GO:1901653 133 0.012
cation homeostasis GO:0055080 195 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
positive regulation of cell differentiation GO:0045597 217 0.012
cellular homeostasis GO:0019725 252 0.012
anterior posterior pattern specification GO:0009952 1 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
cellular response to organic cyclic compound GO:0071407 202 0.012
rna biosynthetic process GO:0032774 380 0.012
purine containing compound metabolic process GO:0072521 253 0.011
steroid metabolic process GO:0008202 73 0.011
response to hypoxia GO:0001666 231 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
nucleoside metabolic process GO:0009116 179 0.011
metal ion homeostasis GO:0055065 186 0.011
regulation of cell development GO:0060284 263 0.011
positive regulation of immune system process GO:0002684 90 0.011
cellular cation homeostasis GO:0030003 180 0.011
regulation of dna metabolic process GO:0051052 60 0.011
protein maturation GO:0051604 68 0.011
heterocycle catabolic process GO:0046700 167 0.011
gamete generation GO:0007276 124 0.011
multi multicellular organism process GO:0044706 138 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
regulation of phosphorylation GO:0042325 248 0.011
transcription dna templated GO:0006351 377 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
purine ribonucleotide metabolic process GO:0009150 227 0.011
positive regulation of gene expression GO:0010628 244 0.011
rhythmic process GO:0048511 156 0.011
small gtpase mediated signal transduction GO:0007264 36 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
synaptic transmission GO:0007268 235 0.011
cardiovascular system development GO:0072358 134 0.011
regulation of cellular localization GO:0060341 263 0.011
cellular response to growth factor stimulus GO:0071363 162 0.011
ribonucleotide metabolic process GO:0009259 231 0.010
response to vitamin GO:0033273 131 0.010
response to ionizing radiation GO:0010212 59 0.010
response to camp GO:0051591 91 0.010
hormone transport GO:0009914 121 0.010
negative regulation of phosphorus metabolic process GO:0010563 80 0.010
nucleoside phosphate catabolic process GO:1901292 140 0.010
glycosyl compound metabolic process GO:1901657 182 0.010
cellular ion homeostasis GO:0006873 184 0.010
cell cycle checkpoint GO:0000075 2 0.010
negative regulation of response to stimulus GO:0048585 155 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.010
positive regulation of secretion GO:0051047 140 0.010
negative regulation of gene expression GO:0010629 199 0.010
negative regulation of secretion GO:0051048 82 0.010
regulation of establishment of planar polarity GO:0090175 2 0.010
organ regeneration GO:0031100 101 0.010
purine nucleoside metabolic process GO:0042278 169 0.010
positive regulation of developmental process GO:0051094 283 0.010
regulation of nucleic acid templated transcription GO:1903506 380 0.010
cellular response to steroid hormone stimulus GO:0071383 93 0.010

Comtd1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
disease of metabolism DOID:0014667 0 0.015
central nervous system disease DOID:331 0 0.012