Rattus norvegicus

0 known processes

Tcf7

transcription factor 7, T-cell specific

Tcf7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.047
oxoacid metabolic process GO:0043436 290 0.045
organic acid metabolic process GO:0006082 292 0.043
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.042
positive regulation of cellular biosynthetic process GO:0031328 295 0.041
positive regulation of multicellular organismal process GO:0051240 387 0.041
regulation of cell proliferation GO:0042127 359 0.041
regulation of multicellular organismal development GO:2000026 376 0.041
positive regulation of biosynthetic process GO:0009891 319 0.040
carboxylic acid metabolic process GO:0019752 289 0.038
cellular amino acid metabolic process GO:0006520 107 0.038
response to nutrient levels GO:0031667 370 0.038
response to extracellular stimulus GO:0009991 380 0.037
nucleic acid templated transcription GO:0097659 379 0.037
neuron differentiation GO:0030182 368 0.036
regulation of molecular function GO:0065009 398 0.035
protein phosphorylation GO:0006468 345 0.034
regulation of neurogenesis GO:0050767 247 0.034
regulation of cell development GO:0060284 263 0.033
amine metabolic process GO:0009308 38 0.033
rna biosynthetic process GO:0032774 380 0.033
central nervous system development GO:0007417 311 0.033
regulation of cell differentiation GO:0045595 320 0.033
intracellular signal transduction GO:0035556 314 0.033
positive regulation of gene expression GO:0010628 244 0.032
regulation of rna biosynthetic process GO:2001141 381 0.032
organophosphate metabolic process GO:0019637 370 0.032
positive regulation of cell proliferation GO:0008284 249 0.031
regulation of nervous system development GO:0051960 264 0.031
cellular amine metabolic process GO:0044106 38 0.031
carbohydrate derivative metabolic process GO:1901135 346 0.031
transcription from rna polymerase ii promoter GO:0006366 252 0.030
rna metabolic process GO:0016070 406 0.030
transcription dna templated GO:0006351 377 0.030
regulation of neuron differentiation GO:0045664 208 0.030
regulation of cellular amino acid metabolic process GO:0006521 2 0.030
regulation of phosphorus metabolic process GO:0051174 349 0.030
regulation of cellular component organization GO:0051128 368 0.030
regulation of catalytic activity GO:0050790 304 0.029
cellular ketone metabolic process GO:0042180 51 0.029
regulation of nucleic acid templated transcription GO:1903506 380 0.029
cell projection organization GO:0030030 302 0.029
cell migration GO:0016477 197 0.029
chemical homeostasis GO:0048878 292 0.029
single organism catabolic process GO:0044712 283 0.029
regulation of transcription dna templated GO:0006355 374 0.028
positive regulation of developmental process GO:0051094 283 0.028
lipid metabolic process GO:0006629 283 0.028
catabolic process GO:0009056 351 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.028
regulation of phosphate metabolic process GO:0019220 349 0.028
cellular component assembly GO:0022607 360 0.028
neuron projection development GO:0031175 273 0.028
regulation of cellular ketone metabolic process GO:0010565 27 0.028
reproductive process GO:0022414 372 0.027
cellular homeostasis GO:0019725 252 0.027
programmed cell death GO:0012501 392 0.027
cellular catabolic process GO:0044248 295 0.027
single organism reproductive process GO:0044702 297 0.027
positive regulation of rna metabolic process GO:0051254 203 0.026
single organism biosynthetic process GO:0044711 342 0.026
localization of cell GO:0051674 202 0.026
cellular response to endogenous stimulus GO:0071495 377 0.026
homeostatic process GO:0042592 331 0.026
purine containing compound metabolic process GO:0072521 253 0.026
cellular component biogenesis GO:0044085 368 0.026
response to hypoxia GO:0001666 231 0.026
regulation of rna metabolic process GO:0051252 391 0.026
regulation of programmed cell death GO:0043067 341 0.026
negative regulation of metabolic process GO:0009892 331 0.026
nucleotide metabolic process GO:0009117 279 0.026
cellular response to oxygen containing compound GO:1901701 386 0.025
response to peptide hormone GO:0043434 278 0.025
transmembrane transport GO:0055085 412 0.025
apoptotic process GO:0006915 381 0.025
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
multi organism reproductive process GO:0044703 262 0.025
response to growth factor GO:0070848 189 0.025
positive regulation of phosphorus metabolic process GO:0010562 262 0.025
ribonucleotide metabolic process GO:0009259 231 0.025
regulation of signal transduction GO:0009966 318 0.025
cell motility GO:0048870 202 0.025
multicellular organismal reproductive process GO:0048609 233 0.025
response to biotic stimulus GO:0009607 226 0.024
response to oxygen levels GO:0070482 265 0.024
cell cell signaling GO:0007267 335 0.024
head development GO:0060322 247 0.024
brain development GO:0007420 247 0.024
positive regulation of rna biosynthetic process GO:1902680 197 0.024
regulation of protein metabolic process GO:0051246 289 0.024
organic substance catabolic process GO:1901575 316 0.024
nucleoside phosphate metabolic process GO:0006753 283 0.024
response to peptide GO:1901652 292 0.024
defense response GO:0006952 194 0.024
anatomical structure morphogenesis GO:0009653 298 0.024
cellular chemical homeostasis GO:0055082 247 0.024
response to decreased oxygen levels GO:0036293 237 0.024
positive regulation of phosphate metabolic process GO:0045937 262 0.024
positive regulation of transcription dna templated GO:0045893 197 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.023
ribose phosphate metabolic process GO:0019693 235 0.023
negative regulation of macromolecule metabolic process GO:0010605 260 0.023
organelle organization GO:0006996 266 0.023
cation transport GO:0006812 382 0.023
neuron development GO:0048666 286 0.023
positive regulation of cell development GO:0010720 176 0.023
regulation of cellular localization GO:0060341 263 0.022
negative regulation of cellular metabolic process GO:0031324 281 0.022
multicellular organism reproduction GO:0032504 233 0.022
macromolecular complex subunit organization GO:0043933 339 0.022
protein complex assembly GO:0006461 263 0.022
behavior GO:0007610 205 0.022
positive regulation of nervous system development GO:0051962 178 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.022
secretion GO:0046903 307 0.021
locomotion GO:0040011 237 0.021
reproduction GO:0000003 245 0.021
regulation of cellular protein metabolic process GO:0032268 267 0.021
ras protein signal transduction GO:0007265 29 0.021
protein complex subunit organization GO:0071822 302 0.021
metal ion transport GO:0030001 289 0.021
response to external biotic stimulus GO:0043207 221 0.021
regulation of cell projection organization GO:0031344 175 0.021
regulation of apoptotic process GO:0042981 335 0.021
intracellular transport GO:0046907 185 0.021
positive regulation of response to stimulus GO:0048584 285 0.021
negative regulation of cell death GO:0060548 229 0.021
purine nucleotide metabolic process GO:0006163 229 0.021
response to estrogen GO:0043627 232 0.021
cellular response to nitrogen compound GO:1901699 210 0.020
regulation of immune system process GO:0002682 123 0.020
response to oxidative stress GO:0006979 186 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
immune system process GO:0002376 204 0.020
purine ribonucleotide metabolic process GO:0009150 227 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.020
small gtpase mediated signal transduction GO:0007264 36 0.020
positive regulation of neurogenesis GO:0050769 165 0.020
response to other organism GO:0051707 220 0.020
cellular response to organic cyclic compound GO:0071407 202 0.020
cellular response to stress GO:0033554 269 0.019
response to nutrient GO:0007584 248 0.019
immune response GO:0006955 104 0.019
response to inorganic substance GO:0010035 377 0.019
Rat
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.019
response to acid chemical GO:0001101 222 0.019
g protein coupled receptor signaling pathway GO:0007186 242 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.019
negative regulation of multicellular organismal process GO:0051241 203 0.019
positive regulation of molecular function GO:0044093 230 0.019
cellular response to growth factor stimulus GO:0071363 162 0.019
macromolecular complex assembly GO:0065003 273 0.019
positive regulation of protein metabolic process GO:0051247 178 0.019
cation homeostasis GO:0055080 195 0.019
response to ethanol GO:0045471 162 0.019
protein complex biogenesis GO:0070271 263 0.019
positive regulation of nucleic acid templated transcription GO:1903508 197 0.019
developmental process involved in reproduction GO:0003006 159 0.019
regulation of protein phosphorylation GO:0001932 183 0.018
ion homeostasis GO:0050801 212 0.018
regulation of protein modification process GO:0031399 194 0.018
regulation of neuron projection development GO:0010975 161 0.018
negative regulation of natural killer cell mediated cytotoxicity GO:0045953 4 0.018
circulatory system process GO:0003013 183 0.018
metal ion homeostasis GO:0055065 186 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
positive regulation of neuron differentiation GO:0045666 126 0.018
positive regulation of cell differentiation GO:0045597 217 0.018
response to carbohydrate GO:0009743 183 0.018
synaptic transmission GO:0007268 235 0.018
negative regulation of signaling GO:0023057 157 0.018
neurological system process GO:0050877 219 0.018
regulation of phosphorylation GO:0042325 248 0.018
regulation of locomotion GO:0040012 148 0.018
ion transmembrane transport GO:0034220 365 0.018
positive regulation of cell death GO:0010942 184 0.018
response to cytokine GO:0034097 215 0.017
Human
cellular ion homeostasis GO:0006873 184 0.017
secretion by cell GO:0032940 248 0.017
regulation of hormone levels GO:0010817 187 0.017
organonitrogen compound biosynthetic process GO:1901566 167 0.017
aging GO:0007568 241 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
regulation of hydrolase activity GO:0051336 143 0.017
divalent inorganic cation homeostasis GO:0072507 165 0.017
gland development GO:0048732 155 0.017
response to wounding GO:0009611 254 0.017
regulation of anatomical structure morphogenesis GO:0022603 141 0.017
negative regulation of innate immune response GO:0045824 4 0.017
ribonucleoside metabolic process GO:0009119 174 0.017
cellular response to hormone stimulus GO:0032870 247 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
cellular component movement GO:0006928 248 0.017
cellular lipid metabolic process GO:0044255 208 0.017
heterocycle catabolic process GO:0046700 167 0.017
positive regulation of signaling GO:0023056 270 0.017
heart morphogenesis GO:0003007 3 0.017
protein oligomerization GO:0051259 191 0.017
positive regulation of phosphorylation GO:0042327 177 0.016
purine nucleoside metabolic process GO:0042278 169 0.016
blood circulation GO:0008015 183 0.016
negative regulation of gene expression GO:0010629 199 0.016
organonitrogen compound catabolic process GO:1901565 179 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
cellular cation homeostasis GO:0030003 180 0.016
regulation of secretion by cell GO:1903530 208 0.016
organophosphate catabolic process GO:0046434 148 0.016
monovalent inorganic cation transport GO:0015672 172 0.016
regulation of intracellular signal transduction GO:1902531 218 0.016
regulation of neuron death GO:1901214 115 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
axis specification GO:0009798 4 0.016
positive regulation of transport GO:0051050 245 0.016
response to ketone GO:1901654 182 0.016
regulation of nucleotide metabolic process GO:0006140 117 0.016
regulation of cell migration GO:0030334 128 0.015
regulation of transferase activity GO:0051338 123 0.015
regeneration GO:0031099 163 0.015
Rat
negative regulation of response to stimulus GO:0048585 155 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
calcium ion homeostasis GO:0055074 162 0.015
sexual reproduction GO:0019953 148 0.015
carbohydrate metabolic process GO:0005975 130 0.015
regulation of cellular component movement GO:0051270 150 0.015
aromatic compound catabolic process GO:0019439 168 0.015
response to molecule of bacterial origin GO:0002237 194 0.015
eye morphogenesis GO:0048592 4 0.015
nucleoside metabolic process GO:0009116 179 0.015
single organism organelle organization GO:1902589 180 0.015
response to estradiol GO:0032355 164 0.015
positive regulation of cell projection organization GO:0031346 111 0.015
lipid biosynthetic process GO:0008610 128 0.015
nitrogen compound transport GO:0071705 229 0.015
positive regulation of immune system process GO:0002684 90 0.015
organophosphate biosynthetic process GO:0090407 143 0.015
negative regulation of apoptotic process GO:0043066 181 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.015
organic cyclic compound catabolic process GO:1901361 175 0.015
carbohydrate derivative catabolic process GO:1901136 147 0.015
cellular metal ion homeostasis GO:0006875 172 0.015
purine ribonucleoside metabolic process GO:0046128 168 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
negative regulation of natural killer cell mediated immunity GO:0002716 4 0.015
negative regulation of cell communication GO:0010648 158 0.015
regulation of secretion GO:0051046 224 0.015
macromolecule localization GO:0033036 252 0.015
cellular response to lipid GO:0071396 201 0.015
regulation of cell motility GO:2000145 131 0.014
purine containing compound catabolic process GO:0072523 138 0.014
nucleotide catabolic process GO:0009166 139 0.014
response to corticosteroid GO:0031960 235 0.014
vesicle mediated transport GO:0016192 181 0.014
circulatory system development GO:0072359 134 0.014
gastrulation GO:0007369 2 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
cation transmembrane transport GO:0098655 263 0.014
negative regulation of developmental process GO:0051093 125 0.014
cell activation GO:0001775 97 0.014
regulation of anatomical structure size GO:0090066 135 0.014
positive regulation of cell communication GO:0010647 271 0.014
inflammatory response GO:0006954 150 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
proteolysis GO:0006508 175 0.014
tissue development GO:0009888 252 0.014
Rat
muscle system process GO:0003012 115 0.014
response to glucocorticoid GO:0051384 223 0.014
regulation of ion transport GO:0043269 245 0.014
negative regulation of cellular biosynthetic process GO:0031327 161 0.014
protein localization GO:0008104 191 0.014
gamete generation GO:0007276 124 0.014
reactive oxygen species biosynthetic process GO:1903409 8 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.014
negative regulation of cell differentiation GO:0045596 99 0.014
cellular response to external stimulus GO:0071496 118 0.014
response to bacterium GO:0009617 200 0.013
inorganic ion transmembrane transport GO:0098660 229 0.013
sex differentiation GO:0007548 113 0.013
growth GO:0040007 165 0.013
positive regulation of protein modification process GO:0031401 142 0.013
female pregnancy GO:0007565 122 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
negative regulation of molecular function GO:0044092 133 0.013
regulation of system process GO:0044057 208 0.013
response to vitamin GO:0033273 131 0.013
development of primary sexual characteristics GO:0045137 107 0.013
single organism intracellular transport GO:1902582 166 0.013
reactive nitrogen species metabolic process GO:2001057 1 0.013
positive regulation of cellular component movement GO:0051272 102 0.013
regulation of kinase activity GO:0043549 117 0.013
cytoplasmic transport GO:0016482 115 0.013
response to mechanical stimulus GO:0009612 134 0.013
response to lipopolysaccharide GO:0032496 191 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
divalent inorganic cation transport GO:0072511 134 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
divalent metal ion transport GO:0070838 132 0.013
salivary gland development GO:0007431 3 0.013
cardiovascular system development GO:0072358 134 0.013
chromosome segregation GO:0007059 2 0.013
reproductive structure development GO:0048608 128 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.013
response to toxic substance GO:0009636 133 0.013
regulation of membrane potential GO:0042391 110 0.013
enzyme linked receptor protein signaling pathway GO:0007167 116 0.013
regulation of response to stress GO:0080134 126 0.013
gonad development GO:0008406 104 0.013
neuron death GO:0070997 127 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
response to monosaccharide GO:0034284 159 0.013
negative regulation of biosynthetic process GO:0009890 168 0.013
nucleoside triphosphate metabolic process GO:0009141 144 0.013
response to metal ion GO:0010038 253 0.012
Rat
ribonucleoside triphosphate catabolic process GO:0009203 122 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
reproductive system development GO:0061458 128 0.012
regulation of protein kinase activity GO:0045859 105 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
positive regulation of neuron projection development GO:0010976 99 0.012
response to reactive oxygen species GO:0000302 120 0.012
establishment of protein localization GO:0045184 141 0.012
cell part morphogenesis GO:0032990 123 0.012
response to transition metal nanoparticle GO:1990267 122 0.012
regulation of catabolic process GO:0009894 113 0.012
cytosolic calcium ion homeostasis GO:0051480 140 0.012
ribonucleoside catabolic process GO:0042454 126 0.012
peptidyl amino acid modification GO:0018193 126 0.012
single organism carbohydrate metabolic process GO:0044723 118 0.012
negative regulation of transport GO:0051051 136 0.012
cell type specific apoptotic process GO:0097285 134 0.012
cellular protein localization GO:0034613 122 0.012
response to radiation GO:0009314 137 0.012
positive regulation of cell migration GO:0030335 96 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
response to glucose GO:0009749 136 0.012
multi multicellular organism process GO:0044706 138 0.012
anterior posterior pattern specification GO:0009952 1 0.012
regulation of response to external stimulus GO:0032101 106 0.012
regulation of canonical wnt signaling pathway GO:0060828 4 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
purine ribonucleotide catabolic process GO:0009154 136 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.012
response to alkaloid GO:0043279 132 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.012
positive regulation of locomotion GO:0040017 102 0.012
positive regulation of programmed cell death GO:0043068 157 0.012
nucleoside catabolic process GO:0009164 126 0.012
response to hexose GO:0009746 144 0.012
positive regulation of cell motility GO:2000147 97 0.012
cardiac chamber development GO:0003205 1 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
cell adhesion GO:0007155 110 0.011
Rat
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
epithelium development GO:0060429 96 0.011
Rat
regulation of cell morphogenesis GO:0022604 77 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
cytoskeleton organization GO:0007010 111 0.011
calcium ion transport GO:0006816 131 0.011
membrane organization GO:0061024 94 0.011
negative regulation of cell proliferation GO:0008285 119 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
ribonucleoside triphosphate metabolic process GO:0009199 141 0.011
reactive oxygen species metabolic process GO:0072593 37 0.011
regulation of reactive oxygen species metabolic process GO:2000377 26 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.011
small molecule biosynthetic process GO:0044283 124 0.011
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.011
embryonic pattern specification GO:0009880 1 0.011
leukocyte activation GO:0045321 76 0.011
purine nucleoside triphosphate metabolic process GO:0009144 141 0.011
vascular process in circulatory system GO:0003018 96 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
negative regulation of neurogenesis GO:0050768 78 0.011
multicellular organismal signaling GO:0035637 44 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.011
cell morphogenesis GO:0000902 142 0.011
negative regulation of rna metabolic process GO:0051253 123 0.011
regulation of metal ion transport GO:0010959 118 0.011
forebrain development GO:0030900 98 0.011
sequestering of calcium ion GO:0051208 8 0.011
anion transport GO:0006820 178 0.011
sequestering of metal ion GO:0051238 9 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
response to temperature stimulus GO:0009266 94 0.010
wound healing GO:0042060 122 0.010
rhythmic process GO:0048511 156 0.010
guanosine containing compound metabolic process GO:1901068 74 0.010
response to amino acid GO:0043200 75 0.010
cell growth GO:0016049 104 0.010
response to purine containing compound GO:0014074 126 0.010
action potential GO:0001508 54 0.010
glycerolipid metabolic process GO:0046486 67 0.010
positive regulation of apoptotic process GO:0043065 154 0.010
negative regulation of nervous system development GO:0051961 79 0.010
lipid storage GO:0019915 1 0.010
alcohol metabolic process GO:0006066 77 0.010
sensory organ development GO:0007423 74 0.010
organic anion transport GO:0015711 132 0.010
negative regulation of transcription dna templated GO:0045892 116 0.010
glycosyl compound catabolic process GO:1901658 126 0.010
positive regulation of nucleoside metabolic process GO:0045979 55 0.010
neuron apoptotic process GO:0051402 88 0.010
biological adhesion GO:0022610 110 0.010
Rat
protein transport GO:0015031 132 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.010
neuron projection morphogenesis GO:0048812 122 0.010
male gamete generation GO:0048232 99 0.010
positive regulation of nucleotide metabolic process GO:0045981 91 0.010

Tcf7 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.026
musculoskeletal system disease DOID:17 0 0.017
disease of metabolism DOID:0014667 0 0.016
sensory system disease DOID:0050155 0 0.015
connective tissue disease DOID:65 0 0.014
central nervous system disease DOID:331 0 0.013
cardiovascular system disease DOID:1287 0 0.013