Rattus norvegicus

0 known processes

Spdef

SAM pointed domain containing ets transcription factor

Spdef biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.061
Mouse
rna biosynthetic process GO:0032774 380 0.055
Human Mouse
neuron differentiation GO:0030182 368 0.050
programmed cell death GO:0012501 392 0.049
Human
positive regulation of biosynthetic process GO:0009891 319 0.038
Mouse
cation transport GO:0006812 382 0.035
organonitrogen compound catabolic process GO:1901565 179 0.034
homeostatic process GO:0042592 331 0.034
neuron development GO:0048666 286 0.034
secretion GO:0046903 307 0.033
regulation of apoptotic process GO:0042981 335 0.033
Human
cellular ketone metabolic process GO:0042180 51 0.032
positive regulation of multicellular organismal process GO:0051240 387 0.032
regulation of transcription dna templated GO:0006355 374 0.031
Human Mouse
cell projection organization GO:0030030 302 0.030
anion transport GO:0006820 178 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
Mouse
nucleic acid templated transcription GO:0097659 379 0.027
Human Mouse
regulation of molecular function GO:0065009 398 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.027
Mouse
regulation of programmed cell death GO:0043067 341 0.027
Human
nitrogen compound transport GO:0071705 229 0.026
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.026
Human Mouse
catabolic process GO:0009056 351 0.026
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
regulation of cell differentiation GO:0045595 320 0.025
Mouse
intracellular signal transduction GO:0035556 314 0.023
regulation of ion transport GO:0043269 245 0.023
negative regulation of cellular metabolic process GO:0031324 281 0.023
Human Mouse
response to oxidative stress GO:0006979 186 0.022
regulation of catalytic activity GO:0050790 304 0.022
cellular amine metabolic process GO:0044106 38 0.021
regulation of multicellular organismal development GO:2000026 376 0.021
neuron projection development GO:0031175 273 0.021
carboxylic acid transport GO:0046942 115 0.021
positive regulation of nucleic acid templated transcription GO:1903508 197 0.021
Mouse
positive regulation of rna metabolic process GO:0051254 203 0.020
Mouse
regulation of cell proliferation GO:0042127 359 0.020
metal ion transport GO:0030001 289 0.020
regulation of cellular ketone metabolic process GO:0010565 27 0.020
positive regulation of molecular function GO:0044093 230 0.020
oxidation reduction process GO:0055114 304 0.020
positive regulation of transcription dna templated GO:0045893 197 0.020
Mouse
positive regulation of phosphate metabolic process GO:0045937 262 0.020
chemical homeostasis GO:0048878 292 0.020
response to extracellular stimulus GO:0009991 380 0.020
negative regulation of metabolic process GO:0009892 331 0.019
Human Mouse
organic substance catabolic process GO:1901575 316 0.019
nucleoside phosphate metabolic process GO:0006753 283 0.019
protein complex biogenesis GO:0070271 263 0.019
heterocycle catabolic process GO:0046700 167 0.019
response to acid chemical GO:0001101 222 0.019
divalent metal ion transport GO:0070838 132 0.019
positive regulation of programmed cell death GO:0043068 157 0.019
Human
regulation of cell projection organization GO:0031344 175 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
Mouse
regulation of rna metabolic process GO:0051252 391 0.018
Human Mouse
transcription dna templated GO:0006351 377 0.018
Human Mouse
cellular homeostasis GO:0019725 252 0.017
regulation of phosphorus metabolic process GO:0051174 349 0.017
cellular response to oxygen containing compound GO:1901701 386 0.017
single organism catabolic process GO:0044712 283 0.017
regulation of cellular amino acid metabolic process GO:0006521 2 0.017
amine metabolic process GO:0009308 38 0.017
ribonucleotide metabolic process GO:0009259 231 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
purine containing compound metabolic process GO:0072521 253 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
apoptotic process GO:0006915 381 0.017
Human
multi organism reproductive process GO:0044703 262 0.017
Fly
negative regulation of signaling GO:0023057 157 0.016
protein complex assembly GO:0006461 263 0.016
organic hydroxy compound metabolic process GO:1901615 115 0.016
cellular catabolic process GO:0044248 295 0.016
response to nutrient GO:0007584 248 0.016
ras protein signal transduction GO:0007265 29 0.016
regulation of protein metabolic process GO:0051246 289 0.016
response to metal ion GO:0010038 253 0.016
cellular component movement GO:0006928 248 0.016
Fly
organic anion transport GO:0015711 132 0.015
gastrulation GO:0007369 2 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
Human Mouse
negative regulation of cell communication GO:0010648 158 0.015
response to nutrient levels GO:0031667 370 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
Human
calcium ion transport GO:0006816 131 0.015
regulation of neurogenesis GO:0050767 247 0.015
regulation of signal transduction GO:0009966 318 0.015
rna metabolic process GO:0016070 406 0.015
Human Mouse
small gtpase mediated signal transduction GO:0007264 36 0.015
regulation of rna biosynthetic process GO:2001141 381 0.015
Human Mouse
protein oligomerization GO:0051259 191 0.015
regulation of anatomical structure morphogenesis GO:0022603 141 0.015
regulation of nervous system development GO:0051960 264 0.015
negative regulation of macromolecule metabolic process GO:0010605 260 0.014
Human Mouse
cell cell signaling GO:0007267 335 0.014
cellular component biogenesis GO:0044085 368 0.014
locomotion GO:0040011 237 0.014
Fly
morphogenesis of embryonic epithelium GO:0016331 3 0.014
anatomical structure morphogenesis GO:0009653 298 0.014
nucleotide metabolic process GO:0009117 279 0.014
regulation of neuron differentiation GO:0045664 208 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
regulation of cell development GO:0060284 263 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
cellular cation homeostasis GO:0030003 180 0.013
cellular response to lipid GO:0071396 201 0.013
positive regulation of gene expression GO:0010628 244 0.013
Mouse
organic cyclic compound catabolic process GO:1901361 175 0.013
cellular response to hormone stimulus GO:0032870 247 0.013
vasoconstriction GO:0042310 54 0.013
regulation of nucleic acid templated transcription GO:1903506 380 0.013
Human Mouse
head development GO:0060322 247 0.013
positive regulation of nervous system development GO:0051962 178 0.013
positive regulation of signaling GO:0023056 270 0.013
cation homeostasis GO:0055080 195 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
positive regulation of rna biosynthetic process GO:1902680 197 0.013
Mouse
transcription from rna polymerase ii promoter GO:0006366 252 0.013
Human Mouse
response to ethanol GO:0045471 162 0.013
cell adhesion GO:0007155 110 0.013
nucleotide catabolic process GO:0009166 139 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
negative regulation of nucleic acid templated transcription GO:1903507 117 0.012
Human Mouse
purine containing compound catabolic process GO:0072523 138 0.012
divalent inorganic cation transport GO:0072511 134 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
Human Mouse
macromolecular complex subunit organization GO:0043933 339 0.012
organophosphate metabolic process GO:0019637 370 0.012
response to ketone GO:1901654 182 0.012
retina morphogenesis in camera type eye GO:0060042 1 0.012
regulation of cellular component organization GO:0051128 368 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
Mouse
organic acid metabolic process GO:0006082 292 0.012
regulation of intracellular signal transduction GO:1902531 218 0.012
multicellular organism growth GO:0035264 1 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
macromolecular complex assembly GO:0065003 273 0.012
positive regulation of cell death GO:0010942 184 0.012
Human
behavior GO:0007610 205 0.012
regulation of cellular amine metabolic process GO:0033238 8 0.012
positive regulation of developmental process GO:0051094 283 0.012
Mouse
response to inorganic substance GO:0010035 377 0.012
cellular chemical homeostasis GO:0055082 247 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
calcium ion homeostasis GO:0055074 162 0.011
regulation of hydrolase activity GO:0051336 143 0.011
aging GO:0007568 241 0.011
positive regulation of lipid catabolic process GO:0050996 4 0.011
neurological system process GO:0050877 219 0.011
circulatory system process GO:0003013 183 0.011
regulation of anatomical structure size GO:0090066 135 0.011
reproduction GO:0000003 245 0.011
Fly
positive regulation of response to stimulus GO:0048584 285 0.011
reactive oxygen species biosynthetic process GO:1903409 8 0.011
cellular response to stress GO:0033554 269 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
response to hypoxia GO:0001666 231 0.011
response to alkaloid GO:0043279 132 0.011
regulation of phosphate metabolic process GO:0019220 349 0.011
brain renin angiotensin system GO:0002035 3 0.011
secretion by cell GO:0032940 248 0.011
epithelium development GO:0060429 96 0.011
Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.011
Human Mouse
regulation of cellular protein metabolic process GO:0032268 267 0.011
negative regulation of biosynthetic process GO:0009890 168 0.011
Human Mouse
synaptic transmission GO:0007268 235 0.011
cellular amino acid metabolic process GO:0006520 107 0.011
cellular component assembly GO:0022607 360 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
regulation of membrane potential GO:0042391 110 0.011
regeneration GO:0031099 163 0.010
negative regulation of transcription dna templated GO:0045892 116 0.010
Human Mouse
negative regulation of gene expression GO:0010629 199 0.010
Human Mouse
regulation of secretion GO:0051046 224 0.010
response to peptide GO:1901652 292 0.010
regulation of protein modification process GO:0031399 194 0.010
ion homeostasis GO:0050801 212 0.010
sex differentiation GO:0007548 113 0.010
axon development GO:0061564 96 0.010
purine ribonucleotide metabolic process GO:0009150 227 0.010
central nervous system development GO:0007417 311 0.010
purine nucleotide catabolic process GO:0006195 136 0.010
multicellular organism reproduction GO:0032504 233 0.010
Fly

Spdef disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.027
disease of anatomical entity DOID:7 0 0.027
sensory system disease DOID:0050155 0 0.018