Rattus norvegicus

41 known processes

Clasp2

cytoplasmic linker associated protein 2

Clasp2 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.137
rna metabolic process GO:0016070 406 0.126
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.122
regulation of cellular component organization GO:0051128 368 0.112
nucleic acid templated transcription GO:0097659 379 0.102
regulation of rna metabolic process GO:0051252 391 0.092
regulation of rna biosynthetic process GO:2001141 381 0.090
regulation of transcription dna templated GO:0006355 374 0.085
regulation of multicellular organismal development GO:2000026 376 0.084
cellular component biogenesis GO:0044085 368 0.082
neuron differentiation GO:0030182 368 0.078
carbohydrate derivative metabolic process GO:1901135 346 0.078
positive regulation of transcription dna templated GO:0045893 197 0.073
regulation of nucleic acid templated transcription GO:1903506 380 0.070
cellular response to stress GO:0033554 269 0.068
macromolecular complex subunit organization GO:0043933 339 0.068
transcription from rna polymerase ii promoter GO:0006366 252 0.068
positive regulation of response to stimulus GO:0048584 285 0.066
cellular catabolic process GO:0044248 295 0.065
organic substance catabolic process GO:1901575 316 0.065
positive regulation of multicellular organismal process GO:0051240 387 0.064
regulation of phosphorus metabolic process GO:0051174 349 0.064
cell projection organization GO:0030030 302 0.063
rna biosynthetic process GO:0032774 380 0.062
transcription dna templated GO:0006351 377 0.062
intracellular signal transduction GO:0035556 314 0.062
organic acid metabolic process GO:0006082 292 0.059
response to oxygen levels GO:0070482 265 0.059
regulation of protein metabolic process GO:0051246 289 0.057
regulation of nervous system development GO:0051960 264 0.057
positive regulation of cellular component organization GO:0051130 200 0.057
anatomical structure morphogenesis GO:0009653 298 0.056
programmed cell death GO:0012501 392 0.056
regulation of cellular ketone metabolic process GO:0010565 27 0.055
positive regulation of cellular biosynthetic process GO:0031328 295 0.054
cellular response to oxygen containing compound GO:1901701 386 0.053
regulation of signal transduction GO:0009966 318 0.053
positive regulation of biosynthetic process GO:0009891 319 0.053
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.053
positive regulation of nervous system development GO:0051962 178 0.052
purine containing compound metabolic process GO:0072521 253 0.052
apoptotic process GO:0006915 381 0.052
regulation of cellular localization GO:0060341 263 0.052
macromolecule localization GO:0033036 252 0.052
cellular component assembly GO:0022607 360 0.051
regulation of protein modification process GO:0031399 194 0.051
positive regulation of nucleic acid templated transcription GO:1903508 197 0.051
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.051
positive regulation of neuron projection development GO:0010976 99 0.050
regulation of cell differentiation GO:0045595 320 0.050
negative regulation of metabolic process GO:0009892 331 0.050
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.049
nucleoside phosphate metabolic process GO:0006753 283 0.049
neuron development GO:0048666 286 0.048
positive regulation of rna metabolic process GO:0051254 203 0.048
central nervous system development GO:0007417 311 0.048
negative regulation of cellular biosynthetic process GO:0031327 161 0.047
negative regulation of cellular metabolic process GO:0031324 281 0.047
negative regulation of macromolecule metabolic process GO:0010605 260 0.047
single organism catabolic process GO:0044712 283 0.046
cellular response to endogenous stimulus GO:0071495 377 0.045
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.045
positive regulation of phosphate metabolic process GO:0045937 262 0.045
carboxylic acid metabolic process GO:0019752 289 0.045
protein localization GO:0008104 191 0.045
cellular protein localization GO:0034613 122 0.045
positive regulation of cell differentiation GO:0045597 217 0.045
regulation of molecular function GO:0065009 398 0.045
cellular ketone metabolic process GO:0042180 51 0.045
purine ribonucleotide metabolic process GO:0009150 227 0.044
regulation of cellular protein metabolic process GO:0032268 267 0.044
head development GO:0060322 247 0.044
cation transport GO:0006812 382 0.044
nucleobase containing small molecule metabolic process GO:0055086 316 0.043
organic cyclic compound catabolic process GO:1901361 175 0.043
positive regulation of developmental process GO:0051094 283 0.043
positive regulation of gene expression GO:0010628 244 0.042
negative regulation of transcription dna templated GO:0045892 116 0.042
positive regulation of signaling GO:0023056 270 0.042
response to decreased oxygen levels GO:0036293 237 0.041
cellular amino acid metabolic process GO:0006520 107 0.041
protein complex assembly GO:0006461 263 0.041
protein phosphorylation GO:0006468 345 0.041
single organism intracellular transport GO:1902582 166 0.041
regulation of cell proliferation GO:0042127 359 0.040
regulation of programmed cell death GO:0043067 341 0.040
cell cell signaling GO:0007267 335 0.040
response to carbohydrate GO:0009743 183 0.039
ribonucleotide metabolic process GO:0009259 231 0.039
amine metabolic process GO:0009308 38 0.039
organophosphate metabolic process GO:0019637 370 0.039
neuron projection development GO:0031175 273 0.039
regulation of cell development GO:0060284 263 0.038
positive regulation of cell development GO:0010720 176 0.038
oxoacid metabolic process GO:0043436 290 0.038
positive regulation of molecular function GO:0044093 230 0.038
negative regulation of gene expression GO:0010629 199 0.038
regulation of neuron projection development GO:0010975 161 0.038
regulation of cellular amine metabolic process GO:0033238 8 0.038
cellular amine metabolic process GO:0044106 38 0.037
secretion GO:0046903 307 0.037
ribose phosphate metabolic process GO:0019693 235 0.037
regulation of cellular amino acid metabolic process GO:0006521 2 0.037
macromolecular complex assembly GO:0065003 273 0.036
response to inorganic substance GO:0010035 377 0.036
regulation of phosphate metabolic process GO:0019220 349 0.036
nucleoside phosphate catabolic process GO:1901292 140 0.036
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.036
negative regulation of nucleic acid templated transcription GO:1903507 117 0.036
enzyme linked receptor protein signaling pathway GO:0007167 116 0.035
negative regulation of biosynthetic process GO:0009890 168 0.035
regulation of apoptotic process GO:0042981 335 0.034
homeostatic process GO:0042592 331 0.034
positive regulation of neurogenesis GO:0050769 165 0.034
glycosyl compound metabolic process GO:1901657 182 0.034
regulation of phosphorylation GO:0042325 248 0.034
neurological system process GO:0050877 219 0.034
brain development GO:0007420 247 0.034
regulation of catalytic activity GO:0050790 304 0.033
regulation of neurogenesis GO:0050767 247 0.033
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.032
positive regulation of rna biosynthetic process GO:1902680 197 0.032
single organism biosynthetic process GO:0044711 342 0.032
positive regulation of transport GO:0051050 245 0.032
nucleotide catabolic process GO:0009166 139 0.032
catabolic process GO:0009056 351 0.032
reproductive process GO:0022414 372 0.032
protein complex subunit organization GO:0071822 302 0.032
cellular component movement GO:0006928 248 0.031
response to extracellular stimulus GO:0009991 380 0.031
purine containing compound catabolic process GO:0072523 138 0.031
response to growth factor GO:0070848 189 0.031
multi organism reproductive process GO:0044703 262 0.031
regulation of neuron differentiation GO:0045664 208 0.031
nucleoside triphosphate metabolic process GO:0009141 144 0.031
transmembrane transport GO:0055085 412 0.030
response to nutrient levels GO:0031667 370 0.030
ribonucleoside triphosphate metabolic process GO:0009199 141 0.030
response to peptide GO:1901652 292 0.030
response to hypoxia GO:0001666 231 0.030
positive regulation of cellular protein metabolic process GO:0032270 167 0.030
ribonucleoside metabolic process GO:0009119 174 0.030
nucleotide metabolic process GO:0009117 279 0.030
glycosyl compound catabolic process GO:1901658 126 0.030
response to monosaccharide GO:0034284 159 0.030
establishment of protein localization GO:0045184 141 0.030
chemical homeostasis GO:0048878 292 0.029
positive regulation of protein metabolic process GO:0051247 178 0.029
single organism organelle organization GO:1902589 180 0.029
cellular macromolecule localization GO:0070727 122 0.029
nucleoside metabolic process GO:0009116 179 0.029
positive regulation of catalytic activity GO:0043085 184 0.029
ion transmembrane transport GO:0034220 365 0.029
organophosphate catabolic process GO:0046434 148 0.029
purine nucleoside catabolic process GO:0006152 124 0.028
regulation of intracellular signal transduction GO:1902531 218 0.028
regulation of protein phosphorylation GO:0001932 183 0.028
positive regulation of phosphorus metabolic process GO:0010562 262 0.028
cell projection morphogenesis GO:0048858 123 0.028
vesicle mediated transport GO:0016192 181 0.028
intracellular transport GO:0046907 185 0.028
response to purine containing compound GO:0014074 126 0.028
positive regulation of cell communication GO:0010647 271 0.027
response to glucose GO:0009749 136 0.027
negative regulation of rna metabolic process GO:0051253 123 0.027
circulatory system process GO:0003013 183 0.027
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.027
reproduction GO:0000003 245 0.027
multicellular organismal reproductive process GO:0048609 233 0.026
cellular chemical homeostasis GO:0055082 247 0.026
regulation of cell projection organization GO:0031344 175 0.026
cellular response to nitrogen compound GO:1901699 210 0.026
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.026
ribonucleoside catabolic process GO:0042454 126 0.026
response to peptide hormone GO:0043434 278 0.025
ribonucleotide catabolic process GO:0009261 136 0.025
nucleobase containing compound catabolic process GO:0034655 152 0.025
regulation of system process GO:0044057 208 0.024
positive regulation of neuron differentiation GO:0045666 126 0.024
regulation of anatomical structure morphogenesis GO:0022603 141 0.024
organelle organization GO:0006996 266 0.024
negative regulation of rna biosynthetic process GO:1902679 118 0.024
carbohydrate derivative catabolic process GO:1901136 147 0.024
nucleoside triphosphate catabolic process GO:0009143 123 0.024
positive regulation of programmed cell death GO:0043068 157 0.024
cell type specific apoptotic process GO:0097285 134 0.024
purine ribonucleoside metabolic process GO:0046128 168 0.024
cardiovascular system development GO:0072358 134 0.023
positive regulation of apoptotic process GO:0043065 154 0.023
aromatic compound catabolic process GO:0019439 168 0.023
cell morphogenesis involved in differentiation GO:0000904 119 0.023
purine nucleotide catabolic process GO:0006195 136 0.023
protein oligomerization GO:0051259 191 0.023
cellular component morphogenesis GO:0032989 155 0.023
positive regulation of cellular amine metabolic process GO:0033240 3 0.023
response to oxidative stress GO:0006979 186 0.022
heterocycle catabolic process GO:0046700 167 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.022
response to cytokine GO:0034097 215 0.022
localization of cell GO:0051674 202 0.022
single organism reproductive process GO:0044702 297 0.022
cellular homeostasis GO:0019725 252 0.022
regulation of ion transport GO:0043269 245 0.022
blood circulation GO:0008015 183 0.022
positive regulation of phosphorylation GO:0042327 177 0.022
organonitrogen compound catabolic process GO:1901565 179 0.022
purine nucleoside metabolic process GO:0042278 169 0.022
positive regulation of nucleotide metabolic process GO:0045981 91 0.022
regulation of response to stress GO:0080134 126 0.022
positive regulation of cell death GO:0010942 184 0.022
regulation of purine nucleotide metabolic process GO:1900542 115 0.022
ribonucleoside triphosphate catabolic process GO:0009203 122 0.022
metal ion transport GO:0030001 289 0.022
cell motility GO:0048870 202 0.022
locomotion GO:0040011 237 0.022
purine ribonucleoside catabolic process GO:0046130 124 0.021
regulation of nucleotide metabolic process GO:0006140 117 0.021
protein complex biogenesis GO:0070271 263 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.021
purine nucleotide metabolic process GO:0006163 229 0.021
synaptic transmission GO:0007268 235 0.021
cellular response to growth factor stimulus GO:0071363 162 0.021
cell migration GO:0016477 197 0.021
intracellular protein transport GO:0006886 79 0.021
purine nucleoside triphosphate metabolic process GO:0009144 141 0.021
metal ion homeostasis GO:0055065 186 0.021
positive regulation of ion transport GO:0043270 94 0.020
multicellular organism reproduction GO:0032504 233 0.020
purine nucleoside triphosphate catabolic process GO:0009146 122 0.020
cell part morphogenesis GO:0032990 123 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.020
regulation of secretion GO:0051046 224 0.020
circulatory system development GO:0072359 134 0.020
regulation of locomotion GO:0040012 148 0.020
regulation of secretion by cell GO:1903530 208 0.020
regulation of cellular catabolic process GO:0031329 101 0.020
response to organophosphorus GO:0046683 102 0.020
positive regulation of cell proliferation GO:0008284 249 0.020
positive regulation of nucleotide catabolic process GO:0030813 53 0.019
anterior posterior pattern specification GO:0009952 1 0.019
carbohydrate derivative biosynthetic process GO:1901137 124 0.019
organophosphate biosynthetic process GO:0090407 143 0.019
inorganic ion transmembrane transport GO:0098660 229 0.019
peptidyl amino acid modification GO:0018193 126 0.019
secretion by cell GO:0032940 248 0.019
purine ribonucleotide catabolic process GO:0009154 136 0.018
learning or memory GO:0007611 90 0.018
ras protein signal transduction GO:0007265 29 0.018
response to wounding GO:0009611 254 0.018
response to insulin GO:0032868 133 0.018
single organism carbohydrate metabolic process GO:0044723 118 0.018
nitrogen compound transport GO:0071705 229 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.018
negative regulation of signaling GO:0023057 157 0.018
single organism cellular localization GO:1902580 102 0.018
cellular response to organonitrogen compound GO:0071417 197 0.017
proteolysis GO:0006508 175 0.017
cation transmembrane transport GO:0098655 263 0.017
ion homeostasis GO:0050801 212 0.017
response to reactive oxygen species GO:0000302 120 0.017
response to lipopolysaccharide GO:0032496 191 0.017
positive regulation of cellular component movement GO:0051272 102 0.017
regulation of dendrite development GO:0050773 59 0.017
response to bacterium GO:0009617 200 0.017
growth GO:0040007 165 0.017
sexual reproduction GO:0019953 148 0.017
negative regulation of apoptotic process GO:0043066 181 0.017
axonogenesis GO:0007409 71 0.017
negative regulation of multicellular organismal process GO:0051241 203 0.017
response to metal ion GO:0010038 253 0.017
small gtpase mediated signal transduction GO:0007264 36 0.017
regulation of purine nucleotide catabolic process GO:0033121 65 0.016
divalent inorganic cation transport GO:0072511 134 0.016
response to hexose GO:0009746 144 0.016
regulation of hydrolase activity GO:0051336 143 0.016
cellular response to lipid GO:0071396 201 0.016
positive regulation of cell projection organization GO:0031346 111 0.016
developmental growth GO:0048589 100 0.016
regulation of cellular component movement GO:0051270 150 0.016
organonitrogen compound biosynthetic process GO:1901566 167 0.016
signal transduction by phosphorylation GO:0023014 144 0.016
muscle system process GO:0003012 115 0.016
regulation of cell motility GO:2000145 131 0.016
regulation of nucleoside metabolic process GO:0009118 66 0.016
neuron death GO:0070997 127 0.016
positive regulation of signal transduction GO:0009967 175 0.016
cell adhesion GO:0007155 110 0.016
cellular response to cytokine stimulus GO:0071345 127 0.016
carbohydrate metabolic process GO:0005975 130 0.015
regulation of organelle organization GO:0033043 80 0.015
negative regulation of transport GO:0051051 136 0.015
neuron apoptotic process GO:0051402 88 0.015
positive regulation of nucleoside metabolic process GO:0045979 55 0.015
multicellular organismal signaling GO:0035637 44 0.015
negative regulation of cellular component organization GO:0051129 83 0.015
response to acid chemical GO:0001101 222 0.015
cell morphogenesis GO:0000902 142 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.015
response to nutrient GO:0007584 248 0.015
female pregnancy GO:0007565 122 0.015
negative regulation of cell differentiation GO:0045596 99 0.015
mapk cascade GO:0000165 140 0.015
rhythmic process GO:0048511 156 0.015
regulation of cell cycle GO:0051726 73 0.015
axon development GO:0061564 96 0.015
calcium ion transport GO:0006816 131 0.015
regulation of response to external stimulus GO:0032101 106 0.014
dendrite development GO:0016358 72 0.014
multi multicellular organism process GO:0044706 138 0.014
regulation of synaptic transmission GO:0050804 141 0.014
dna metabolic process GO:0006259 96 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.014
response to ethanol GO:0045471 162 0.014
forebrain development GO:0030900 98 0.014
tissue development GO:0009888 252 0.014
negative regulation of cell death GO:0060548 229 0.014
negative regulation of response to stimulus GO:0048585 155 0.014
cellular response to hormone stimulus GO:0032870 247 0.014
cytoplasmic transport GO:0016482 115 0.014
neuronal action potential GO:0019228 35 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
response to radiation GO:0009314 137 0.014
regulation of cellular component biogenesis GO:0044087 86 0.013
negative regulation of developmental process GO:0051093 125 0.013
nucleoside catabolic process GO:0009164 126 0.013
regulation of protein kinase activity GO:0045859 105 0.013
protein localization to organelle GO:0033365 57 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
positive regulation of protein modification process GO:0031401 142 0.013
neuron projection morphogenesis GO:0048812 122 0.013
gastrulation GO:0007369 2 0.013
negative regulation of cell proliferation GO:0008285 119 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.013
regulation of catabolic process GO:0009894 113 0.013
cation homeostasis GO:0055080 195 0.013
response to hydrogen peroxide GO:0042542 89 0.013
regulation of neuron death GO:1901214 115 0.013
heart development GO:0007507 72 0.013
anion transport GO:0006820 178 0.013
gtp catabolic process GO:0006184 71 0.013
response to ammonium ion GO:0060359 71 0.013
regulation of transferase activity GO:0051338 123 0.013
guanosine containing compound metabolic process GO:1901068 74 0.013
regulation of anatomical structure size GO:0090066 135 0.013
negative regulation of cell communication GO:0010648 158 0.013
regulation of neuron apoptotic process GO:0043523 83 0.013
regulation of canonical wnt signaling pathway GO:0060828 4 0.013
positive regulation of cellular catabolic process GO:0031331 71 0.013
regulation of blood circulation GO:1903522 110 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
transmission of nerve impulse GO:0019226 42 0.013
behavior GO:0007610 205 0.012
inflammatory response GO:0006954 150 0.012
cellular cation homeostasis GO:0030003 180 0.012
gamete generation GO:0007276 124 0.012
protein transport GO:0015031 132 0.012
positive regulation of locomotion GO:0040017 102 0.012
protein homooligomerization GO:0051260 91 0.012
dendrite morphogenesis GO:0048813 43 0.012
axis specification GO:0009798 4 0.012
regulation of membrane potential GO:0042391 110 0.012
negative regulation of protein metabolic process GO:0051248 114 0.012
regulation of cell morphogenesis GO:0022604 77 0.012
cellular response to peptide hormone stimulus GO:0071375 120 0.012
response to cgmp GO:0070305 3 0.012
response to estrogen GO:0043627 232 0.012
cellular lipid metabolic process GO:0044255 208 0.012
cell cycle GO:0007049 101 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
cellular response to insulin stimulus GO:0032869 81 0.012
defense response GO:0006952 194 0.012
spindle organization GO:0007051 2 0.012
potassium ion transport GO:0006813 97 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
regulation of gtpase activity GO:0043087 57 0.012
calcium ion homeostasis GO:0055074 162 0.012
protein targeting GO:0006605 61 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.011
regulation of homeostatic process GO:0032844 101 0.011
response to alkaloid GO:0043279 132 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
response to other organism GO:0051707 220 0.011
cell cycle checkpoint GO:0000075 2 0.011
protein modification by small protein conjugation GO:0032446 31 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.011
action potential GO:0001508 54 0.011
regulation of growth GO:0040008 105 0.011
regulation of gtp catabolic process GO:0033124 58 0.011
gtp metabolic process GO:0046039 72 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
heart process GO:0003015 57 0.011
regulation of metal ion transport GO:0010959 118 0.011
regulation of mapk cascade GO:0043408 116 0.011
lipid metabolic process GO:0006629 283 0.011
embryonic pattern specification GO:0009880 1 0.011
immune system process GO:0002376 204 0.011
cellular divalent inorganic cation homeostasis GO:0072503 162 0.011
cellular metal ion homeostasis GO:0006875 172 0.011
regulation of vesicle mediated transport GO:0060627 81 0.011
carboxylic acid transport GO:0046942 115 0.011
cytoskeleton organization GO:0007010 111 0.011
response to molecule of bacterial origin GO:0002237 194 0.011
cellular response to oxidative stress GO:0034599 76 0.011
cytokine mediated signaling pathway GO:0019221 43 0.010
dephosphorylation GO:0016311 98 0.010
organic hydroxy compound transport GO:0015850 77 0.010
single organism behavior GO:0044708 130 0.010
positive regulation of immune system process GO:0002684 90 0.010
cellular ion homeostasis GO:0006873 184 0.010
protein autophosphorylation GO:0046777 66 0.010
inorganic cation transmembrane transport GO:0098662 202 0.010
regulation of immune system process GO:0002682 123 0.010
glucose homeostasis GO:0042593 75 0.010
regulation of hormone levels GO:0010817 187 0.010
circadian rhythm GO:0007623 88 0.010
eye morphogenesis GO:0048592 4 0.010
cellular carbohydrate metabolic process GO:0044262 72 0.010
positive regulation of catabolic process GO:0009896 78 0.010

Clasp2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.025
nervous system disease DOID:863 0 0.025
central nervous system disease DOID:331 0 0.022
sensory system disease DOID:0050155 0 0.010