Rattus norvegicus

17 known processes

Ppm1d

protein phosphatase 1D magnesium-dependent, delta isoform

Ppm1d biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription dna templated GO:0006355 374 0.132
transcription dna templated GO:0006351 377 0.118
regulation of nucleic acid templated transcription GO:1903506 380 0.103
nucleic acid templated transcription GO:0097659 379 0.101
rna metabolic process GO:0016070 406 0.100
rna biosynthetic process GO:0032774 380 0.098
programmed cell death GO:0012501 392 0.090
regulation of rna metabolic process GO:0051252 391 0.089
negative regulation of metabolic process GO:0009892 331 0.088
regulation of rna biosynthetic process GO:2001141 381 0.085
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.084
negative regulation of cellular metabolic process GO:0031324 281 0.083
negative regulation of rna biosynthetic process GO:1902679 118 0.077
negative regulation of gene expression GO:0010629 199 0.075
regulation of programmed cell death GO:0043067 341 0.075
organic substance catabolic process GO:1901575 316 0.072
negative regulation of macromolecule metabolic process GO:0010605 260 0.065
negative regulation of biosynthetic process GO:0009890 168 0.065
regulation of apoptotic process GO:0042981 335 0.063
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.062
cellular component biogenesis GO:0044085 368 0.056
negative regulation of rna metabolic process GO:0051253 123 0.055
regulation of cellular component organization GO:0051128 368 0.051
intracellular signal transduction GO:0035556 314 0.050
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.047
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.047
organelle organization GO:0006996 266 0.046
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.045
reproductive process GO:0022414 372 0.044
carboxylic acid metabolic process GO:0019752 289 0.043
regulation of signal transduction GO:0009966 318 0.041
cellular catabolic process GO:0044248 295 0.041
regulation of cell differentiation GO:0045595 320 0.040
positive regulation of developmental process GO:0051094 283 0.040
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.039
cation transport GO:0006812 382 0.039
positive regulation of multicellular organismal process GO:0051240 387 0.039
single organism organelle organization GO:1902589 180 0.039
cellular response to oxygen containing compound GO:1901701 386 0.039
negative regulation of nucleic acid templated transcription GO:1903507 117 0.039
positive regulation of rna biosynthetic process GO:1902680 197 0.038
organic acid metabolic process GO:0006082 292 0.038
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.038
regulation of molecular function GO:0065009 398 0.036
regulation of multicellular organismal development GO:2000026 376 0.036
regulation of catalytic activity GO:0050790 304 0.036
catabolic process GO:0009056 351 0.035
oxoacid metabolic process GO:0043436 290 0.034
single organism catabolic process GO:0044712 283 0.034
regulation of cell development GO:0060284 263 0.033
multi organism reproductive process GO:0044703 262 0.032
central nervous system development GO:0007417 311 0.032
protein complex subunit organization GO:0071822 302 0.032
regulation of neurogenesis GO:0050767 247 0.031
regulation of phosphate metabolic process GO:0019220 349 0.031
macromolecular complex subunit organization GO:0043933 339 0.031
regulation of cell proliferation GO:0042127 359 0.031
negative regulation of transcription dna templated GO:0045892 116 0.031
cellular component assembly GO:0022607 360 0.031
single organism reproductive process GO:0044702 297 0.031
regulation of protein metabolic process GO:0051246 289 0.031
positive regulation of biosynthetic process GO:0009891 319 0.031
response to inorganic substance GO:0010035 377 0.030
neuron differentiation GO:0030182 368 0.030
response to nutrient levels GO:0031667 370 0.030
positive regulation of cellular biosynthetic process GO:0031328 295 0.030
reproduction GO:0000003 245 0.029
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.029
cellular response to nitrogen compound GO:1901699 210 0.029
cellular amino acid metabolic process GO:0006520 107 0.029
organophosphate metabolic process GO:0019637 370 0.028
regulation of phosphorus metabolic process GO:0051174 349 0.028
nucleoside phosphate metabolic process GO:0006753 283 0.028
brain development GO:0007420 247 0.028
transcription from rna polymerase ii promoter GO:0006366 252 0.028
cellular response to endogenous stimulus GO:0071495 377 0.028
cellular ketone metabolic process GO:0042180 51 0.028
regulation of cellular protein metabolic process GO:0032268 267 0.028
positive regulation of molecular function GO:0044093 230 0.027
apoptotic process GO:0006915 381 0.027
cellular amine metabolic process GO:0044106 38 0.027
negative regulation of apoptotic process GO:0043066 181 0.027
ribonucleoside triphosphate metabolic process GO:0009199 141 0.027
small gtpase mediated signal transduction GO:0007264 36 0.026
ras protein signal transduction GO:0007265 29 0.025
cell projection organization GO:0030030 302 0.025
anatomical structure morphogenesis GO:0009653 298 0.025
nucleobase containing small molecule metabolic process GO:0055086 316 0.025
protein localization GO:0008104 191 0.025
head development GO:0060322 247 0.025
neuron projection development GO:0031175 273 0.025
aging GO:0007568 241 0.025
positive regulation of cell differentiation GO:0045597 217 0.025
multicellular organism reproduction GO:0032504 233 0.025
regulation of intracellular signal transduction GO:1902531 218 0.024
positive regulation of cell death GO:0010942 184 0.024
regulation of nervous system development GO:0051960 264 0.024
multicellular organismal reproductive process GO:0048609 233 0.024
negative regulation of cellular biosynthetic process GO:0031327 161 0.024
amine metabolic process GO:0009308 38 0.024
neuron development GO:0048666 286 0.024
positive regulation of rna metabolic process GO:0051254 203 0.024
purine containing compound metabolic process GO:0072521 253 0.023
response to decreased oxygen levels GO:0036293 237 0.023
response to extracellular stimulus GO:0009991 380 0.023
cellular response to stress GO:0033554 269 0.022
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
positive regulation of gene expression GO:0010628 244 0.022
regulation of phosphorylation GO:0042325 248 0.022
single organism biosynthetic process GO:0044711 342 0.022
response to hypoxia GO:0001666 231 0.022
positive regulation of signal transduction GO:0009967 175 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.021
positive regulation of nervous system development GO:0051962 178 0.021
negative regulation of programmed cell death GO:0043069 183 0.021
negative regulation of cell death GO:0060548 229 0.021
purine ribonucleoside catabolic process GO:0046130 124 0.021
positive regulation of signaling GO:0023056 270 0.020
metal ion transport GO:0030001 289 0.020
sexual reproduction GO:0019953 148 0.020
positive regulation of nucleic acid templated transcription GO:1903508 197 0.020
regulation of catabolic process GO:0009894 113 0.020
positive regulation of cell communication GO:0010647 271 0.019
positive regulation of transcription dna templated GO:0045893 197 0.019
negative regulation of signaling GO:0023057 157 0.019
carbohydrate derivative metabolic process GO:1901135 346 0.019
protein complex biogenesis GO:0070271 263 0.019
multicellular organism growth GO:0035264 1 0.019
macromolecular complex assembly GO:0065003 273 0.019
positive regulation of response to stimulus GO:0048584 285 0.019
response to oxygen levels GO:0070482 265 0.019
nucleotide metabolic process GO:0009117 279 0.019
neuron death GO:0070997 127 0.019
proteolysis GO:0006508 175 0.019
response to peptide GO:1901652 292 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
regulation of hydrolase activity GO:0051336 143 0.018
regulation of cellular ketone metabolic process GO:0010565 27 0.018
regulation of proteasomal protein catabolic process GO:0061136 4 0.018
intracellular transport GO:0046907 185 0.018
negative regulation of multicellular organismal process GO:0051241 203 0.018
protein oligomerization GO:0051259 191 0.018
positive regulation of phosphorus metabolic process GO:0010562 262 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
positive regulation of catalytic activity GO:0043085 184 0.018
cellular response to hormone stimulus GO:0032870 247 0.018
macromolecule localization GO:0033036 252 0.018
ion transmembrane transport GO:0034220 365 0.018
neuron apoptotic process GO:0051402 88 0.017
response to metal ion GO:0010038 253 0.017
negative regulation of cell communication GO:0010648 158 0.017
ribonucleoside metabolic process GO:0009119 174 0.017
regulation of protein modification process GO:0031399 194 0.017
regulation of protein phosphorylation GO:0001932 183 0.017
positive regulation of neurogenesis GO:0050769 165 0.017
developmental process involved in reproduction GO:0003006 159 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
regulation of cell projection organization GO:0031344 175 0.017
gamete generation GO:0007276 124 0.017
nucleoside catabolic process GO:0009164 126 0.017
purine nucleotide metabolic process GO:0006163 229 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
growth GO:0040007 165 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
cell cell signaling GO:0007267 335 0.016
positive regulation of programmed cell death GO:0043068 157 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.016
aromatic compound catabolic process GO:0019439 168 0.016
response to growth factor GO:0070848 189 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
lipid metabolic process GO:0006629 283 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
protein complex assembly GO:0006461 263 0.016
ribonucleotide metabolic process GO:0009259 231 0.016
organophosphate biosynthetic process GO:0090407 143 0.016
negative regulation of cell proliferation GO:0008285 119 0.015
cellular protein localization GO:0034613 122 0.015
protein phosphorylation GO:0006468 345 0.015
cellular response to peptide GO:1901653 133 0.015
positive regulation of phosphate metabolic process GO:0045937 262 0.015
peptidyl amino acid modification GO:0018193 126 0.015
vesicle mediated transport GO:0016192 181 0.015
enzyme linked receptor protein signaling pathway GO:0007167 116 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
heterocycle catabolic process GO:0046700 167 0.015
purine ribonucleotide catabolic process GO:0009154 136 0.015
negative regulation of protein metabolic process GO:0051248 114 0.015
purine nucleoside triphosphate metabolic process GO:0009144 141 0.014
synaptic transmission GO:0007268 235 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
monovalent inorganic cation transport GO:0015672 172 0.014
organophosphate catabolic process GO:0046434 148 0.014
glycosyl compound metabolic process GO:1901657 182 0.014
cell projection morphogenesis GO:0048858 123 0.014
positive regulation of cell development GO:0010720 176 0.014
homeostatic process GO:0042592 331 0.014
spermatogenesis GO:0007283 99 0.014
positive regulation of cell projection organization GO:0031346 111 0.014
chromosome segregation GO:0007059 2 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.014
behavior GO:0007610 205 0.014
circulatory system development GO:0072359 134 0.014
negative regulation of transport GO:0051051 136 0.014
response to acid chemical GO:0001101 222 0.014
positive regulation of neuron differentiation GO:0045666 126 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 91 0.013
cation transmembrane transport GO:0098655 263 0.013
regulation of neuron projection development GO:0010975 161 0.013
regulation of transferase activity GO:0051338 123 0.013
single organism intracellular transport GO:1902582 166 0.013
nucleoside metabolic process GO:0009116 179 0.013
cell cycle GO:0007049 101 0.013
regulation of cellular localization GO:0060341 263 0.013
cellular component movement GO:0006928 248 0.013
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.013
cell type specific apoptotic process GO:0097285 134 0.013
regulation of nucleotide catabolic process GO:0030811 65 0.013
cellular lipid metabolic process GO:0044255 208 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
protein transport GO:0015031 132 0.013
cellular macromolecule localization GO:0070727 122 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
immune system process GO:0002376 204 0.013
negative regulation of cellular protein metabolic process GO:0032269 106 0.013
response to peptide hormone GO:0043434 278 0.013
dephosphorylation GO:0016311 98 0.013
male gamete generation GO:0048232 99 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
regulation of hormone levels GO:0010817 187 0.012
response to ethanol GO:0045471 162 0.012
regulation of cell cycle GO:0051726 73 0.012
negative regulation of innate immune response GO:0045824 4 0.012
organonitrogen compound biosynthetic process GO:1901566 167 0.012
sulfur compound metabolic process GO:0006790 70 0.012
transmembrane transport GO:0055085 412 0.012
response to oxidative stress GO:0006979 186 0.012
secretion GO:0046903 307 0.012
cellular chemical homeostasis GO:0055082 247 0.012
regulation of cellular catabolic process GO:0031329 101 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
chemical homeostasis GO:0048878 292 0.012
axis specification GO:0009798 4 0.012
protein modification by small protein conjugation or removal GO:0070647 35 0.012
positive regulation of catabolic process GO:0009896 78 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
positive regulation of cell proliferation GO:0008284 249 0.012
cellular response to insulin stimulus GO:0032869 81 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
macromolecule catabolic process GO:0009057 58 0.012
response to estrogen GO:0043627 232 0.012
negative regulation of developmental process GO:0051093 125 0.012
regulation of organelle organization GO:0033043 80 0.012
response to glucose GO:0009749 136 0.012
positive regulation of apoptotic process GO:0043065 154 0.011
single organism cellular localization GO:1902580 102 0.011
regulation of neuron differentiation GO:0045664 208 0.011
negative regulation of molecular function GO:0044092 133 0.011
nitrogen compound transport GO:0071705 229 0.011
purine ribonucleoside metabolic process GO:0046128 168 0.011
cellular nitrogen compound catabolic process GO:0044270 163 0.011
ribonucleoside triphosphate catabolic process GO:0009203 122 0.011
regulation of kinase activity GO:0043549 117 0.011
gland development GO:0048732 155 0.011
cellular response to oxidative stress GO:0034599 76 0.011
carbohydrate derivative catabolic process GO:1901136 147 0.011
regulation of growth GO:0040008 105 0.011
defense response GO:0006952 194 0.011
response to external biotic stimulus GO:0043207 221 0.011
cellular homeostasis GO:0019725 252 0.011
positive regulation of protein modification process GO:0031401 142 0.011
protein modification by small protein conjugation GO:0032446 31 0.011
cellular component morphogenesis GO:0032989 155 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
regulation of metal ion transport GO:0010959 118 0.011
neuron projection morphogenesis GO:0048812 122 0.011
regulation of protein kinase activity GO:0045859 105 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
cytoplasmic transport GO:0016482 115 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
response to carbohydrate GO:0009743 183 0.010
cell part morphogenesis GO:0032990 123 0.010
intracellular protein transport GO:0006886 79 0.010
regulation of ion transport GO:0043269 245 0.010
cell cycle checkpoint GO:0000075 2 0.010
alpha amino acid metabolic process GO:1901605 71 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
negative regulation of cell cycle phase transition GO:1901988 4 0.010
positive regulation of cellular catabolic process GO:0031331 71 0.010
cell growth GO:0016049 104 0.010
cellular response to organic cyclic compound GO:0071407 202 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.010

Ppm1d disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.019
muscular disease DOID:0080000 0 0.016
disease of anatomical entity DOID:7 0 0.016
musculoskeletal system disease DOID:17 0 0.016
cancer DOID:162 0 0.014
nervous system disease DOID:863 0 0.012
organ system cancer DOID:0050686 0 0.012
muscle tissue disease DOID:66 0 0.012
central nervous system disease DOID:331 0 0.012
myopathy DOID:423 0 0.010
muscular dystrophy DOID:9884 0 0.010