Rattus norvegicus

0 known processes

Ppm1k

protein phosphatase 1K (PP2C domain containing)

(Aliases: RGD1308501)

Ppm1k biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular component organization GO:0051128 368 0.074
negative regulation of metabolic process GO:0009892 331 0.057
catabolic process GO:0009056 351 0.052
positive regulation of developmental process GO:0051094 283 0.051
regulation of molecular function GO:0065009 398 0.050
organophosphate metabolic process GO:0019637 370 0.049
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.048
single organism biosynthetic process GO:0044711 342 0.048
nucleic acid templated transcription GO:0097659 379 0.048
homeostatic process GO:0042592 331 0.048
regulation of signal transduction GO:0009966 318 0.045
positive regulation of cellular component organization GO:0051130 200 0.044
organic acid metabolic process GO:0006082 292 0.044
cellular response to oxygen containing compound GO:1901701 386 0.044
rna metabolic process GO:0016070 406 0.043
ribonucleotide metabolic process GO:0009259 231 0.043
purine containing compound metabolic process GO:0072521 253 0.042
response to nutrient levels GO:0031667 370 0.042
neuron development GO:0048666 286 0.041
cellular ketone metabolic process GO:0042180 51 0.041
protein complex subunit organization GO:0071822 302 0.040
neuron differentiation GO:0030182 368 0.040
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.040
cellular component biogenesis GO:0044085 368 0.039
response to extracellular stimulus GO:0009991 380 0.039
protein complex assembly GO:0006461 263 0.039
carbohydrate derivative metabolic process GO:1901135 346 0.039
positive regulation of cellular biosynthetic process GO:0031328 295 0.038
regulation of phosphorus metabolic process GO:0051174 349 0.038
regulation of ion transport GO:0043269 245 0.038
cellular component morphogenesis GO:0032989 155 0.038
regulation of multicellular organismal development GO:2000026 376 0.038
nucleobase containing small molecule metabolic process GO:0055086 316 0.038
negative regulation of cellular metabolic process GO:0031324 281 0.038
cellular component assembly GO:0022607 360 0.037
carboxylic acid metabolic process GO:0019752 289 0.036
regulation of neuron apoptotic process GO:0043523 83 0.036
regulation of rna biosynthetic process GO:2001141 381 0.035
cellular amino acid metabolic process GO:0006520 107 0.035
regulation of cell differentiation GO:0045595 320 0.035
response to nutrient GO:0007584 248 0.034
oxoacid metabolic process GO:0043436 290 0.034
lipid metabolic process GO:0006629 283 0.034
rhythmic process GO:0048511 156 0.034
cellular catabolic process GO:0044248 295 0.034
purine ribonucleotide metabolic process GO:0009150 227 0.033
anatomical structure morphogenesis GO:0009653 298 0.033
ion transmembrane transport GO:0034220 365 0.032
regulation of nucleic acid templated transcription GO:1903506 380 0.032
positive regulation of molecular function GO:0044093 230 0.032
nucleoside metabolic process GO:0009116 179 0.032
organic substance catabolic process GO:1901575 316 0.032
regulation of programmed cell death GO:0043067 341 0.032
regulation of catalytic activity GO:0050790 304 0.031
regulation of protein metabolic process GO:0051246 289 0.031
transmembrane transport GO:0055085 412 0.031
nucleotide metabolic process GO:0009117 279 0.031
organelle organization GO:0006996 266 0.031
response to radiation GO:0009314 137 0.031
amine metabolic process GO:0009308 38 0.031
positive regulation of biosynthetic process GO:0009891 319 0.031
intracellular signal transduction GO:0035556 314 0.030
nucleoside phosphate metabolic process GO:0006753 283 0.030
regulation of phosphate metabolic process GO:0019220 349 0.030
tissue development GO:0009888 252 0.030
neuron projection development GO:0031175 273 0.030
purine nucleoside metabolic process GO:0042278 169 0.030
cation transport GO:0006812 382 0.030
chemical homeostasis GO:0048878 292 0.030
macromolecular complex assembly GO:0065003 273 0.030
positive regulation of multicellular organismal process GO:0051240 387 0.029
regulation of phosphorylation GO:0042325 248 0.029
regulation of apoptotic process GO:0042981 335 0.029
rna biosynthetic process GO:0032774 380 0.028
regulation of cellular amino acid metabolic process GO:0006521 2 0.028
neuron projection morphogenesis GO:0048812 122 0.028
purine nucleotide metabolic process GO:0006163 229 0.028
positive regulation of cellular protein metabolic process GO:0032270 167 0.028
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.028
anion transport GO:0006820 178 0.028
cellular response to nitrogen compound GO:1901699 210 0.028
response to bacterium GO:0009617 200 0.027
macromolecular complex subunit organization GO:0043933 339 0.027
cellular amine metabolic process GO:0044106 38 0.027
ribonucleoside metabolic process GO:0009119 174 0.027
positive regulation of protein modification process GO:0031401 142 0.027
regulation of cellular protein metabolic process GO:0032268 267 0.027
central nervous system development GO:0007417 311 0.026
single organism reproductive process GO:0044702 297 0.026
response to biotic stimulus GO:0009607 226 0.026
regulation of intracellular signal transduction GO:1902531 218 0.026
negative regulation of macromolecule metabolic process GO:0010605 260 0.026
regulation of cellular ketone metabolic process GO:0010565 27 0.026
single organism catabolic process GO:0044712 283 0.026
multicellular organism reproduction GO:0032504 233 0.026
programmed cell death GO:0012501 392 0.026
organonitrogen compound catabolic process GO:1901565 179 0.026
purine ribonucleoside metabolic process GO:0046128 168 0.025
positive regulation of transport GO:0051050 245 0.025
response to molecule of bacterial origin GO:0002237 194 0.025
transcription from rna polymerase ii promoter GO:0006366 252 0.025
response to inorganic substance GO:0010035 377 0.025
transcription dna templated GO:0006351 377 0.025
negative regulation of cellular biosynthetic process GO:0031327 161 0.025
circadian rhythm GO:0007623 88 0.025
multicellular organismal reproductive process GO:0048609 233 0.024
protein phosphorylation GO:0006468 345 0.024
regulation of catabolic process GO:0009894 113 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.024
single organism intracellular transport GO:1902582 166 0.024
regulation of system process GO:0044057 208 0.024
regulation of cell proliferation GO:0042127 359 0.024
aromatic compound catabolic process GO:0019439 168 0.024
response to decreased oxygen levels GO:0036293 237 0.024
regulation of rna metabolic process GO:0051252 391 0.024
muscle system process GO:0003012 115 0.024
nucleoside triphosphate metabolic process GO:0009141 144 0.024
aging GO:0007568 241 0.023
nucleotide catabolic process GO:0009166 139 0.023
carbohydrate derivative catabolic process GO:1901136 147 0.023
positive regulation of programmed cell death GO:0043068 157 0.023
cellular response to stress GO:0033554 269 0.023
positive regulation of cell proliferation GO:0008284 249 0.023
regulation of cell development GO:0060284 263 0.023
heterocycle catabolic process GO:0046700 167 0.023
response to oxidative stress GO:0006979 186 0.023
glycosyl compound metabolic process GO:1901657 182 0.022
reproductive process GO:0022414 372 0.022
purine nucleoside triphosphate metabolic process GO:0009144 141 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.022
response to carbohydrate GO:0009743 183 0.022
response to other organism GO:0051707 220 0.022
negative regulation of cell death GO:0060548 229 0.022
dna metabolic process GO:0006259 96 0.022
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.022
regulation of cellular amine metabolic process GO:0033238 8 0.022
macromolecule localization GO:0033036 252 0.021
positive regulation of cell development GO:0010720 176 0.021
regulation of cellular localization GO:0060341 263 0.021
positive regulation of phosphate metabolic process GO:0045937 262 0.021
synaptic transmission GO:0007268 235 0.021
reproduction GO:0000003 245 0.021
response to peptide GO:1901652 292 0.021
ribonucleoside triphosphate metabolic process GO:0009199 141 0.021
organic cyclic compound catabolic process GO:1901361 175 0.021
organophosphate catabolic process GO:0046434 148 0.021
response to lipopolysaccharide GO:0032496 191 0.021
cellular divalent inorganic cation homeostasis GO:0072503 162 0.021
cellular component movement GO:0006928 248 0.020
ion homeostasis GO:0050801 212 0.020
regulation of transcription dna templated GO:0006355 374 0.020
negative regulation of biosynthetic process GO:0009890 168 0.020
purine ribonucleotide catabolic process GO:0009154 136 0.020
positive regulation of phosphorylation GO:0042327 177 0.020
regulation of cellular catabolic process GO:0031329 101 0.020
sulfur compound metabolic process GO:0006790 70 0.020
axis specification GO:0009798 4 0.020
positive regulation of apoptotic process GO:0043065 154 0.020
regulation of hydrolase activity GO:0051336 143 0.020
cellular nitrogen compound catabolic process GO:0044270 163 0.020
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.020
apoptotic process GO:0006915 381 0.019
cell part morphogenesis GO:0032990 123 0.019
cell morphogenesis GO:0000902 142 0.019
cellular homeostasis GO:0019725 252 0.019
small gtpase mediated signal transduction GO:0007264 36 0.019
response to external biotic stimulus GO:0043207 221 0.018
positive regulation of response to stimulus GO:0048584 285 0.018
ribose phosphate metabolic process GO:0019693 235 0.018
multi organism reproductive process GO:0044703 262 0.018
immune response GO:0006955 104 0.018
growth GO:0040007 165 0.018
g protein coupled receptor signaling pathway GO:0007186 242 0.018
regulation of protein modification process GO:0031399 194 0.018
regulation of anatomical structure morphogenesis GO:0022603 141 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.018
response to oxygen levels GO:0070482 265 0.018
response to vitamin GO:0033273 131 0.018
positive regulation of ion transport GO:0043270 94 0.018
regulation of ion transmembrane transport GO:0034765 121 0.018
response to acid chemical GO:0001101 222 0.018
cell cycle checkpoint GO:0000075 2 0.017
positive regulation of phosphorus metabolic process GO:0010562 262 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
positive regulation of cell differentiation GO:0045597 217 0.017
nucleoside monophosphate metabolic process GO:0009123 93 0.017
response to growth factor GO:0070848 189 0.017
ras protein signal transduction GO:0007265 29 0.017
protein localization GO:0008104 191 0.017
muscle contraction GO:0006936 88 0.017
regulation of neurogenesis GO:0050767 247 0.017
positive regulation of cell death GO:0010942 184 0.017
defense response GO:0006952 194 0.017
organonitrogen compound biosynthetic process GO:1901566 167 0.017
response to hypoxia GO:0001666 231 0.016
cellular chemical homeostasis GO:0055082 247 0.016
cell type specific apoptotic process GO:0097285 134 0.016
cellular response to lipid GO:0071396 201 0.016
heart morphogenesis GO:0003007 3 0.016
cellular calcium ion homeostasis GO:0006874 160 0.016
regulation of neuron differentiation GO:0045664 208 0.016
negative regulation of rna metabolic process GO:0051253 123 0.016
monocarboxylic acid metabolic process GO:0032787 152 0.016
secretion GO:0046903 307 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.016
positive regulation of cellular amine metabolic process GO:0033240 3 0.016
response to amino acid GO:0043200 75 0.016
cation homeostasis GO:0055080 195 0.016
response to cytokine GO:0034097 215 0.016
negative regulation of response to stimulus GO:0048585 155 0.016
neuron death GO:0070997 127 0.016
secretion by cell GO:0032940 248 0.016
cellular cation homeostasis GO:0030003 180 0.016
metal ion homeostasis GO:0055065 186 0.016
response to ketone GO:1901654 182 0.016
response to estrogen GO:0043627 232 0.016
regulation of nervous system development GO:0051960 264 0.015
circulatory system development GO:0072359 134 0.015
ribonucleoside catabolic process GO:0042454 126 0.015
cellular response to endogenous stimulus GO:0071495 377 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.015
response to hexose GO:0009746 144 0.015
regulation of neuron death GO:1901214 115 0.015
response to metal ion GO:0010038 253 0.015
protein oligomerization GO:0051259 191 0.015
alpha amino acid metabolic process GO:1901605 71 0.015
nitrogen compound transport GO:0071705 229 0.015
cellular response to hormone stimulus GO:0032870 247 0.015
divalent inorganic cation homeostasis GO:0072507 165 0.015
positive regulation of transcription dna templated GO:0045893 197 0.015
proteolysis GO:0006508 175 0.015
head development GO:0060322 247 0.015
single organism behavior GO:0044708 130 0.015
negative regulation of protein metabolic process GO:0051248 114 0.015
positive regulation of rna metabolic process GO:0051254 203 0.015
single organism organelle organization GO:1902589 180 0.015
cell projection morphogenesis GO:0048858 123 0.014
positive regulation of cellular catabolic process GO:0031331 71 0.014
small molecule biosynthetic process GO:0044283 124 0.014
calcium ion homeostasis GO:0055074 162 0.014
positive regulation of signaling GO:0023056 270 0.014
protein complex biogenesis GO:0070271 263 0.014
response to toxic substance GO:0009636 133 0.014
muscle cell proliferation GO:0033002 84 0.014
regulation of membrane potential GO:0042391 110 0.014
anterior posterior pattern specification GO:0009952 1 0.014
negative regulation of rna biosynthetic process GO:1902679 118 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
cell projection organization GO:0030030 302 0.014
cell migration GO:0016477 197 0.014
response to camp GO:0051591 91 0.014
negative regulation of transcription dna templated GO:0045892 116 0.014
response to temperature stimulus GO:0009266 94 0.014
response to peptide hormone GO:0043434 278 0.014
regulation of neuron projection development GO:0010975 161 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.014
regulation of nucleotide metabolic process GO:0006140 117 0.014
cellular metal ion homeostasis GO:0006875 172 0.014
negative regulation of molecular function GO:0044092 133 0.014
establishment of protein localization GO:0045184 141 0.014
single organism carbohydrate metabolic process GO:0044723 118 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.014
purine nucleoside monophosphate metabolic process GO:0009126 84 0.014
response to organophosphorus GO:0046683 102 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.014
metal ion transport GO:0030001 289 0.014
regulation of lipid metabolic process GO:0019216 68 0.014
negative regulation of transport GO:0051051 136 0.013
purine containing compound catabolic process GO:0072523 138 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
sexual reproduction GO:0019953 148 0.013
gamete generation GO:0007276 124 0.013
regulation of homeostatic process GO:0032844 101 0.013
ribonucleotide catabolic process GO:0009261 136 0.013
response to estradiol GO:0032355 164 0.013
blood circulation GO:0008015 183 0.013
behavior GO:0007610 205 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
response to reactive oxygen species GO:0000302 120 0.013
negative regulation of cell communication GO:0010648 158 0.013
cellular protein complex assembly GO:0043623 44 0.013
cytosolic calcium ion homeostasis GO:0051480 140 0.013
organic acid transport GO:0015849 116 0.013
response to glucose GO:0009749 136 0.013
response to hydrogen peroxide GO:0042542 89 0.013
regulation of protein phosphorylation GO:0001932 183 0.013
positive regulation of protein metabolic process GO:0051247 178 0.013
response to ethanol GO:0045471 162 0.013
regulation of smooth muscle cell proliferation GO:0048660 75 0.013
monovalent inorganic cation transport GO:0015672 172 0.013
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.013
maintenance of location GO:0051235 17 0.013
positive regulation of catalytic activity GO:0043085 184 0.013
vesicle mediated transport GO:0016192 181 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.013
cytoplasmic transport GO:0016482 115 0.013
localization of cell GO:0051674 202 0.013
cellular response to acid chemical GO:0071229 75 0.013
positive regulation of immune system process GO:0002684 90 0.013
circulatory system process GO:0003013 183 0.013
regulation of ion transmembrane transporter activity GO:0032412 48 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.012
cellular response to oxidative stress GO:0034599 76 0.012
cell morphogenesis involved in differentiation GO:0000904 119 0.012
nucleoside catabolic process GO:0009164 126 0.012
regulation of muscle system process GO:0090257 79 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.012
neurological system process GO:0050877 219 0.012
regulation of anatomical structure size GO:0090066 135 0.012
locomotion GO:0040011 237 0.012
immune system process GO:0002376 204 0.012
positive regulation of secretion GO:0051047 140 0.012
regulation of secretion GO:0051046 224 0.012
cellular carbohydrate metabolic process GO:0044262 72 0.012
cardiovascular system development GO:0072358 134 0.012
negative regulation of gene expression GO:0010629 199 0.012
smooth muscle cell proliferation GO:0048659 77 0.012
response to glucocorticoid GO:0051384 223 0.012
regulation of transporter activity GO:0032409 50 0.012
negative regulation of apoptotic process GO:0043066 181 0.012
regulation of cell projection organization GO:0031344 175 0.012
multicellular organism growth GO:0035264 1 0.012
nucleoside triphosphate catabolic process GO:0009143 123 0.012
purine nucleoside catabolic process GO:0006152 124 0.012
brain development GO:0007420 247 0.012
monosaccharide metabolic process GO:0005996 61 0.012
response to tumor necrosis factor GO:0034612 56 0.012
regulation of hormone levels GO:0010817 187 0.012
positive regulation of nervous system development GO:0051962 178 0.012
negative regulation of programmed cell death GO:0043069 183 0.012
cellular response to reactive oxygen species GO:0034614 55 0.012
purine ribonucleoside catabolic process GO:0046130 124 0.012
lipid storage GO:0019915 1 0.012
cell cell signaling GO:0007267 335 0.012
response to mechanical stimulus GO:0009612 134 0.012
negative regulation of cell cycle phase transition GO:1901988 4 0.012
single organism cellular localization GO:1902580 102 0.012
heart contraction GO:0060047 57 0.012
negative regulation of developmental process GO:0051093 125 0.012
ribonucleoside triphosphate catabolic process GO:0009203 122 0.012
calcium ion transport GO:0006816 131 0.012
nucleoside phosphate biosynthetic process GO:1901293 102 0.012
membrane organization GO:0061024 94 0.012
cellular macromolecular complex assembly GO:0034622 58 0.011
regulation of dna metabolic process GO:0051052 60 0.011
protein transport GO:0015031 132 0.011
regulation of blood circulation GO:1903522 110 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
response to purine containing compound GO:0014074 126 0.011
carbohydrate derivative biosynthetic process GO:1901137 124 0.011
peptidyl amino acid modification GO:0018193 126 0.011
carboxylic acid transport GO:0046942 115 0.011
glycosyl compound catabolic process GO:1901658 126 0.011
multi multicellular organism process GO:0044706 138 0.011
developmental process involved in reproduction GO:0003006 159 0.011
cellular response to peptide GO:1901653 133 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
protein heterooligomerization GO:0051291 89 0.011
response to monosaccharide GO:0034284 159 0.011
negative regulation of neuron death GO:1901215 69 0.011
regulation of vesicle mediated transport GO:0060627 81 0.011
actin filament based process GO:0030029 86 0.011
neuron neuron synaptic transmission GO:0007270 60 0.011
axonogenesis GO:0007409 71 0.011
rna localization GO:0006403 4 0.011
cellular lipid metabolic process GO:0044255 208 0.011
divalent metal ion transport GO:0070838 132 0.011
cell growth GO:0016049 104 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
dna integrity checkpoint GO:0031570 2 0.010
positive regulation of nucleotide metabolic process GO:0045981 91 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
negative regulation of nucleic acid templated transcription GO:1903507 117 0.010
female pregnancy GO:0007565 122 0.010
ribonucleoside monophosphate metabolic process GO:0009161 88 0.010
positive regulation of organelle organization GO:0010638 48 0.010
regulation of metal ion transport GO:0010959 118 0.010
cellular response to organic cyclic compound GO:0071407 202 0.010
regulation of purine nucleotide metabolic process GO:1900542 115 0.010
axon development GO:0061564 96 0.010
positive regulation of gene expression GO:0010628 244 0.010
lipid biosynthetic process GO:0008610 128 0.010
cellular response to cytokine stimulus GO:0071345 127 0.010
negative regulation of catalytic activity GO:0043086 103 0.010
response to corticosteroid GO:0031960 235 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
regulation of response to stress GO:0080134 126 0.010
cellular ion homeostasis GO:0006873 184 0.010

Ppm1k disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017
disease of metabolism DOID:0014667 0 0.015
Human
inherited metabolic disorder DOID:655 0 0.013
Human
central nervous system disease DOID:331 0 0.011