Rattus norvegicus

0 known processes

Dem1

defects in morphology 1 homolog (S. cerevisiae)

(Aliases: RGD1309802)

Dem1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
immune system process GO:0002376 204 0.075
carboxylic acid metabolic process GO:0019752 289 0.061
regulation of transcription dna templated GO:0006355 374 0.044
regulation of intracellular signal transduction GO:1902531 218 0.043
regulation of rna biosynthetic process GO:2001141 381 0.043
regulation of rna metabolic process GO:0051252 391 0.041
transcription from rna polymerase ii promoter GO:0006366 252 0.041
response to external biotic stimulus GO:0043207 221 0.039
transmembrane transport GO:0055085 412 0.038
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.037
rna biosynthetic process GO:0032774 380 0.037
innate immune response GO:0045087 35 0.037
organic acid metabolic process GO:0006082 292 0.037
response to molecule of bacterial origin GO:0002237 194 0.036
positive regulation of molecular function GO:0044093 230 0.036
positive regulation of multicellular organismal process GO:0051240 387 0.035
transcription dna templated GO:0006351 377 0.034
regulation of molecular function GO:0065009 398 0.034
positive regulation of nucleic acid templated transcription GO:1903508 197 0.033
regulation of nucleic acid templated transcription GO:1903506 380 0.033
response to inorganic substance GO:0010035 377 0.033
positive regulation of rna biosynthetic process GO:1902680 197 0.033
regulation of cellular localization GO:0060341 263 0.032
positive regulation of biosynthetic process GO:0009891 319 0.032
cation homeostasis GO:0055080 195 0.031
positive regulation of transcription dna templated GO:0045893 197 0.031
nucleic acid templated transcription GO:0097659 379 0.031
regulation of signal transduction GO:0009966 318 0.031
oxoacid metabolic process GO:0043436 290 0.031
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.030
response to other organism GO:0051707 220 0.030
positive regulation of rna metabolic process GO:0051254 203 0.030
regulation of secretion by cell GO:1903530 208 0.030
divalent inorganic cation homeostasis GO:0072507 165 0.030
nitrogen compound transport GO:0071705 229 0.030
intracellular signal transduction GO:0035556 314 0.029
neuron apoptotic process GO:0051402 88 0.029
response to lipopolysaccharide GO:0032496 191 0.028
regulation of cellular amine metabolic process GO:0033238 8 0.028
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.028
cellular amino acid metabolic process GO:0006520 107 0.027
cation transport GO:0006812 382 0.026
positive regulation of response to stimulus GO:0048584 285 0.026
metal ion homeostasis GO:0055065 186 0.026
ion transmembrane transport GO:0034220 365 0.026
positive regulation of cell communication GO:0010647 271 0.025
ion homeostasis GO:0050801 212 0.025
rna metabolic process GO:0016070 406 0.025
regulation of protein metabolic process GO:0051246 289 0.025
cellular response to nitrogen compound GO:1901699 210 0.025
positive regulation of cell differentiation GO:0045597 217 0.025
regulation of cellular amino acid metabolic process GO:0006521 2 0.025
cytokine production GO:0001816 61 0.025
positive regulation of cellular biosynthetic process GO:0031328 295 0.024
positive regulation of gene expression GO:0010628 244 0.024
response to bacterium GO:0009617 200 0.024
response to mechanical stimulus GO:0009612 134 0.024
multi organism reproductive process GO:0044703 262 0.023
anion transport GO:0006820 178 0.023
regulation of neuron death GO:1901214 115 0.023
homeostatic process GO:0042592 331 0.023
macromolecule localization GO:0033036 252 0.023
inflammatory response GO:0006954 150 0.023
cellular chemical homeostasis GO:0055082 247 0.023
regulation of ion transport GO:0043269 245 0.023
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.023
cellular response to organic cyclic compound GO:0071407 202 0.023
cellular amine metabolic process GO:0044106 38 0.023
inorganic ion transmembrane transport GO:0098660 229 0.022
regulation of protein modification process GO:0031399 194 0.022
aging GO:0007568 241 0.022
programmed cell death GO:0012501 392 0.022
multicellular organismal reproductive process GO:0048609 233 0.022
defense response GO:0006952 194 0.022
protein oligomerization GO:0051259 191 0.022
neuron death GO:0070997 127 0.022
regulation of multicellular organismal development GO:2000026 376 0.022
positive regulation of apoptotic process GO:0043065 154 0.022
cellular ion homeostasis GO:0006873 184 0.021
response to wounding GO:0009611 254 0.021
positive regulation of signaling GO:0023056 270 0.021
cellular response to oxygen containing compound GO:1901701 386 0.021
cellular cation homeostasis GO:0030003 180 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.021
positive regulation of developmental process GO:0051094 283 0.020
circulatory system process GO:0003013 183 0.020
positive regulation of cell death GO:0010942 184 0.020
response to metal ion GO:0010038 253 0.020
regulation of cell development GO:0060284 263 0.020
secretion by cell GO:0032940 248 0.020
secretion GO:0046903 307 0.020
cellular response to peptide hormone stimulus GO:0071375 120 0.020
neuron differentiation GO:0030182 368 0.020
organic cyclic compound catabolic process GO:1901361 175 0.019
regulation of cell differentiation GO:0045595 320 0.019
regulation of anatomical structure morphogenesis GO:0022603 141 0.019
organophosphate metabolic process GO:0019637 370 0.019
erythrocyte differentiation GO:0030218 1 0.019
protein heterooligomerization GO:0051291 89 0.019
regulation of catalytic activity GO:0050790 304 0.018
heterocycle catabolic process GO:0046700 167 0.018
response to transition metal nanoparticle GO:1990267 122 0.018
response to biotic stimulus GO:0009607 226 0.018
amine metabolic process GO:0009308 38 0.018
apoptotic process GO:0006915 381 0.018
response to toxic substance GO:0009636 133 0.018
carboxylic acid transport GO:0046942 115 0.018
chemical homeostasis GO:0048878 292 0.018
protein localization GO:0008104 191 0.018
cellular homeostasis GO:0019725 252 0.018
response to ethanol GO:0045471 162 0.018
positive regulation of cell development GO:0010720 176 0.018
reproductive process GO:0022414 372 0.018
developmental process involved in reproduction GO:0003006 159 0.017
response to peptide hormone GO:0043434 278 0.017
organic acid transport GO:0015849 116 0.017
nucleotide metabolic process GO:0009117 279 0.017
regulation of homeostatic process GO:0032844 101 0.017
central nervous system development GO:0007417 311 0.017
regulation of phosphorus metabolic process GO:0051174 349 0.017
cellular response to cytokine stimulus GO:0071345 127 0.017
carbohydrate derivative metabolic process GO:1901135 346 0.017
calcium ion homeostasis GO:0055074 162 0.017
cellular response to growth factor stimulus GO:0071363 162 0.017
regulation of secretion GO:0051046 224 0.017
response to radiation GO:0009314 137 0.017
cellular calcium ion homeostasis GO:0006874 160 0.017
positive regulation of secretion by cell GO:1903532 128 0.016
cellular catabolic process GO:0044248 295 0.016
response to acid chemical GO:0001101 222 0.016
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.016
regulation of neuron apoptotic process GO:0043523 83 0.016
nucleoside phosphate catabolic process GO:1901292 140 0.016
positive regulation of secretion GO:0051047 140 0.016
cation transmembrane transport GO:0098655 263 0.016
response to zinc ion GO:0010043 39 0.016
multicellular organism reproduction GO:0032504 233 0.016
response to peptide GO:1901652 292 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
negative regulation of cellular metabolic process GO:0031324 281 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
regulation of cellular ketone metabolic process GO:0010565 27 0.016
cellular ketone metabolic process GO:0042180 51 0.016
cellular metal ion homeostasis GO:0006875 172 0.015
response to growth factor GO:0070848 189 0.015
single organism catabolic process GO:0044712 283 0.015
protein phosphorylation GO:0006468 345 0.015
cellular response to stress GO:0033554 269 0.015
single organism organelle organization GO:1902589 180 0.015
cellular component assembly GO:0022607 360 0.015
nucleobase containing compound catabolic process GO:0034655 152 0.015
protein complex subunit organization GO:0071822 302 0.015
organic anion transport GO:0015711 132 0.015
cellular component biogenesis GO:0044085 368 0.015
response to decreased oxygen levels GO:0036293 237 0.015
response to cytokine GO:0034097 215 0.015
regulation of phosphate metabolic process GO:0019220 349 0.014
response to oxygen levels GO:0070482 265 0.014
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.014
enzyme linked receptor protein signaling pathway GO:0007167 116 0.014
organelle organization GO:0006996 266 0.014
cellular response to lipopolysaccharide GO:0071222 55 0.014
regulation of cellular protein metabolic process GO:0032268 267 0.014
cellular response to endogenous stimulus GO:0071495 377 0.014
negative regulation of cell communication GO:0010648 158 0.014
cellular response to organonitrogen compound GO:0071417 197 0.014
metal ion transport GO:0030001 289 0.014
positive regulation of cytokine production GO:0001819 42 0.014
positive regulation of mapk cascade GO:0043410 92 0.014
positive regulation of intracellular signal transduction GO:1902533 138 0.014
response to oxidative stress GO:0006979 186 0.014
intracellular transport GO:0046907 185 0.014
cytoplasmic transport GO:0016482 115 0.014
regulation of mrna splicing via spliceosome GO:0048024 3 0.013
amino acid transport GO:0006865 70 0.013
positive regulation of signal transduction GO:0009967 175 0.013
brain development GO:0007420 247 0.013
cytosolic calcium ion homeostasis GO:0051480 140 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
regulation of cytokine production GO:0001817 56 0.013
cellular response to peptide GO:1901653 133 0.013
cytokine biosynthetic process GO:0042089 3 0.013
positive regulation of immune system process GO:0002684 90 0.013
aromatic compound catabolic process GO:0019439 168 0.013
single organism reproductive process GO:0044702 297 0.013
tumor necrosis factor mediated signaling pathway GO:0033209 4 0.013
negative regulation of macromolecule metabolic process GO:0010605 260 0.013
negative regulation of metabolic process GO:0009892 331 0.013
purine containing compound metabolic process GO:0072521 253 0.012
nucleoside metabolic process GO:0009116 179 0.012
locomotion GO:0040011 237 0.012
single organism behavior GO:0044708 130 0.012
regulation of response to stress GO:0080134 126 0.012
cellular component movement GO:0006928 248 0.012
regulation of defense response GO:0031347 68 0.012
negative regulation of signaling GO:0023057 157 0.012
amide transport GO:0042886 105 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.012
response to insulin GO:0032868 133 0.012
regulation of protein phosphorylation GO:0001932 183 0.012
regulation of response to external stimulus GO:0032101 106 0.012
single organism intracellular transport GO:1902582 166 0.012
regulation of immune system process GO:0002682 123 0.012
regulation of nervous system development GO:0051960 264 0.012
response to ketone GO:1901654 182 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
positive regulation of phosphorus metabolic process GO:0010562 262 0.012
neuron development GO:0048666 286 0.012
negative regulation of transport GO:0051051 136 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
reactive oxygen species biosynthetic process GO:1903409 8 0.012
regulation of kinase activity GO:0043549 117 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
negative regulation of response to stimulus GO:0048585 155 0.012
macromolecular complex subunit organization GO:0043933 339 0.012
positive regulation of cellular protein metabolic process GO:0032270 167 0.012
reproduction GO:0000003 245 0.012
proteolysis GO:0006508 175 0.012
glycosyl compound metabolic process GO:1901657 182 0.012
positive regulation of catalytic activity GO:0043085 184 0.011
cell cell signaling GO:0007267 335 0.011
female pregnancy GO:0007565 122 0.011
regulation of cell proliferation GO:0042127 359 0.011
organic substance catabolic process GO:1901575 316 0.011
reactive nitrogen species metabolic process GO:2001057 1 0.011
regulation of cellular component organization GO:0051128 368 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
oligopeptide transport GO:0006857 4 0.011
response to hexose GO:0009746 144 0.011
regulation of peptide transport GO:0090087 87 0.011
response to corticosteroid GO:0031960 235 0.011
neuron projection development GO:0031175 273 0.011
positive regulation of phosphorylation GO:0042327 177 0.011
regulation of system process GO:0044057 208 0.011
ribose phosphate metabolic process GO:0019693 235 0.011
axis specification GO:0009798 4 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
nucleobase containing small molecule metabolic process GO:0055086 316 0.011
blood vessel development GO:0001568 69 0.011
catabolic process GO:0009056 351 0.011
actin cytoskeleton organization GO:0030036 73 0.011
single organism biosynthetic process GO:0044711 342 0.011
anatomical structure morphogenesis GO:0009653 298 0.011
muscle system process GO:0003012 115 0.011
response to glucocorticoid GO:0051384 223 0.011
head development GO:0060322 247 0.011
regulation of interleukin 6 production GO:0032675 12 0.011
positive regulation of defense response GO:0031349 37 0.011
negative regulation of innate immune response GO:0045824 4 0.011
positive regulation of cellular amine metabolic process GO:0033240 3 0.011
response to estradiol GO:0032355 164 0.010
signal release GO:0023061 145 0.010
cellular response to acid chemical GO:0071229 75 0.010
negative regulation of protein metabolic process GO:0051248 114 0.010
positive regulation of programmed cell death GO:0043068 157 0.010
negative regulation of cellular amine metabolic process GO:0033239 3 0.010
positive regulation of transport GO:0051050 245 0.010
cellular protein localization GO:0034613 122 0.010
positive regulation of hydrolase activity GO:0051345 86 0.010
regulation of transferase activity GO:0051338 123 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
forebrain development GO:0030900 98 0.010
phospholipid metabolic process GO:0006644 61 0.010
nucleoside phosphate metabolic process GO:0006753 283 0.010
spermatogenesis GO:0007283 99 0.010
maintenance of location GO:0051235 17 0.010
positive regulation of protein metabolic process GO:0051247 178 0.010

Dem1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.025
cancer DOID:162 0 0.021
organ system cancer DOID:0050686 0 0.021
sensory system disease DOID:0050155 0 0.017
disease of anatomical entity DOID:7 0 0.017
nervous system disease DOID:863 0 0.017