Rattus norvegicus

0 known processes

Setd8

SET domain containing (lysine methyltransferase) 8

(Aliases: RGD1305893)

Setd8 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
rna biosynthetic process GO:0032774 380 0.109
negative regulation of cellular metabolic process GO:0031324 281 0.082
regulation of nucleic acid templated transcription GO:1903506 380 0.053
cellular response to oxygen containing compound GO:1901701 386 0.049
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.049
negative regulation of rna biosynthetic process GO:1902679 118 0.048
regulation of rna biosynthetic process GO:2001141 381 0.048
protein phosphorylation GO:0006468 345 0.044
negative regulation of metabolic process GO:0009892 331 0.044
protein complex subunit organization GO:0071822 302 0.044
macromolecular complex subunit organization GO:0043933 339 0.043
oxoacid metabolic process GO:0043436 290 0.042
cellular homeostasis GO:0019725 252 0.039
regulation of cellular localization GO:0060341 263 0.039
transcription dna templated GO:0006351 377 0.038
transcription from rna polymerase ii promoter GO:0006366 252 0.036
organophosphate metabolic process GO:0019637 370 0.036
nucleic acid templated transcription GO:0097659 379 0.036
cellular chemical homeostasis GO:0055082 247 0.036
regulation of cell differentiation GO:0045595 320 0.035
negative regulation of macromolecule metabolic process GO:0010605 260 0.035
regulation of secretion by cell GO:1903530 208 0.035
nucleotide metabolic process GO:0009117 279 0.034
positive regulation of gene expression GO:0010628 244 0.034
homeostatic process GO:0042592 331 0.033
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.032
regulation of rna metabolic process GO:0051252 391 0.032
positive regulation of biosynthetic process GO:0009891 319 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.031
regulation of secretion GO:0051046 224 0.031
cation transport GO:0006812 382 0.030
secretion by cell GO:0032940 248 0.030
regulation of transcription dna templated GO:0006355 374 0.029
regulation of multicellular organismal development GO:2000026 376 0.029
secretion GO:0046903 307 0.029
negative regulation of biosynthetic process GO:0009890 168 0.029
response to glucose GO:0009749 136 0.028
regulation of neurogenesis GO:0050767 247 0.028
cell cycle checkpoint GO:0000075 2 0.028
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
cellular component assembly GO:0022607 360 0.027
nitrogen compound transport GO:0071705 229 0.027
regulation of protein modification process GO:0031399 194 0.027
nucleobase containing small molecule metabolic process GO:0055086 316 0.026
regulation of phosphorus metabolic process GO:0051174 349 0.026
regulation of cellular protein metabolic process GO:0032268 267 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.025
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.025
regulation of hormone levels GO:0010817 187 0.025
regulation of phosphorylation GO:0042325 248 0.024
cellular component biogenesis GO:0044085 368 0.024
rna metabolic process GO:0016070 406 0.024
macromolecule localization GO:0033036 252 0.024
chemical homeostasis GO:0048878 292 0.024
positive regulation of molecular function GO:0044093 230 0.024
negative regulation of transcription dna templated GO:0045892 116 0.024
cell projection organization GO:0030030 302 0.024
regulation of apoptotic process GO:0042981 335 0.023
response to monosaccharide GO:0034284 159 0.023
positive regulation of transcription dna templated GO:0045893 197 0.023
positive regulation of cell death GO:0010942 184 0.023
negative regulation of gene expression GO:0010629 199 0.022
cellular amino acid metabolic process GO:0006520 107 0.022
positive regulation of cell proliferation GO:0008284 249 0.022
organic acid metabolic process GO:0006082 292 0.022
negative regulation of nucleic acid templated transcription GO:1903507 117 0.022
regulation of nervous system development GO:0051960 264 0.022
regulation of molecular function GO:0065009 398 0.022
positive regulation of apoptotic process GO:0043065 154 0.021
organophosphate biosynthetic process GO:0090407 143 0.021
positive regulation of nucleic acid templated transcription GO:1903508 197 0.021
regulation of programmed cell death GO:0043067 341 0.021
protein complex biogenesis GO:0070271 263 0.021
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
regulation of cell proliferation GO:0042127 359 0.020
programmed cell death GO:0012501 392 0.020
negative regulation of cellular biosynthetic process GO:0031327 161 0.020
positive regulation of cellular amine metabolic process GO:0033240 3 0.020
positive regulation of programmed cell death GO:0043068 157 0.020
protein complex assembly GO:0006461 263 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
amine metabolic process GO:0009308 38 0.020
single organism intracellular transport GO:1902582 166 0.020
response to carbohydrate GO:0009743 183 0.020
cellular ketone metabolic process GO:0042180 51 0.020
regulation of protein metabolic process GO:0051246 289 0.020
chromatin assembly or disassembly GO:0006333 1 0.019
regulation of response to stress GO:0080134 126 0.019
positive regulation of cellular component organization GO:0051130 200 0.019
response to decreased oxygen levels GO:0036293 237 0.019
negative regulation of cell differentiation GO:0045596 99 0.019
g protein coupled receptor signaling pathway GO:0007186 242 0.018
response to nutrient levels GO:0031667 370 0.018
cellular response to stress GO:0033554 269 0.018
defense response GO:0006952 194 0.018
negative regulation of cell communication GO:0010648 158 0.018
apoptotic process GO:0006915 381 0.018
heterocycle catabolic process GO:0046700 167 0.018
regulation of signal transduction GO:0009966 318 0.018
aging GO:0007568 241 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.018
negative regulation of cell death GO:0060548 229 0.018
regulation of protein kinase activity GO:0045859 105 0.018
organic cyclic compound catabolic process GO:1901361 175 0.018
vesicle mediated transport GO:0016192 181 0.018
negative regulation of rna metabolic process GO:0051253 123 0.017
ion homeostasis GO:0050801 212 0.017
macromolecular complex assembly GO:0065003 273 0.017
positive regulation of catalytic activity GO:0043085 184 0.017
single organism biosynthetic process GO:0044711 342 0.017
dna metabolic process GO:0006259 96 0.017
ribonucleotide metabolic process GO:0009259 231 0.017
regulation of hormone secretion GO:0046883 106 0.017
carboxylic acid metabolic process GO:0019752 289 0.017
positive regulation of cellular protein metabolic process GO:0032270 167 0.017
purine containing compound metabolic process GO:0072521 253 0.017
organ regeneration GO:0031100 101 0.016
neuron differentiation GO:0030182 368 0.016
divalent inorganic cation homeostasis GO:0072507 165 0.016
cellular component morphogenesis GO:0032989 155 0.016
inorganic ion transmembrane transport GO:0098660 229 0.016
positive regulation of cell differentiation GO:0045597 217 0.016
purine nucleoside triphosphate metabolic process GO:0009144 141 0.016
cellular divalent inorganic cation homeostasis GO:0072503 162 0.016
carbohydrate derivative metabolic process GO:1901135 346 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.016
protein oligomerization GO:0051259 191 0.016
dephosphorylation GO:0016311 98 0.016
regulation of cell projection organization GO:0031344 175 0.016
cellular cation homeostasis GO:0030003 180 0.016
intracellular transport GO:0046907 185 0.016
regulation of catalytic activity GO:0050790 304 0.016
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
regulation of protein phosphorylation GO:0001932 183 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
cellular ion homeostasis GO:0006873 184 0.015
response to oxygen levels GO:0070482 265 0.015
positive regulation of rna metabolic process GO:0051254 203 0.015
regulation of peptide transport GO:0090087 87 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
positive regulation of developmental process GO:0051094 283 0.015
alcohol metabolic process GO:0006066 77 0.015
cellular amine metabolic process GO:0044106 38 0.015
regulation of homeostatic process GO:0032844 101 0.015
nucleoside phosphate metabolic process GO:0006753 283 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
cation homeostasis GO:0055080 195 0.015
central nervous system development GO:0007417 311 0.015
regulation of peptide hormone secretion GO:0090276 80 0.015
negative regulation of cell development GO:0010721 82 0.015
positive regulation of protein metabolic process GO:0051247 178 0.015
cell cell signaling GO:0007267 335 0.015
response to hypoxia GO:0001666 231 0.014
organelle organization GO:0006996 266 0.014
response to cytokine GO:0034097 215 0.014
nucleoside metabolic process GO:0009116 179 0.014
response to inorganic substance GO:0010035 377 0.014
neuron projection development GO:0031175 273 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
regulation of cellular ketone metabolic process GO:0010565 27 0.014
protein localization GO:0008104 191 0.014
negative regulation of cell cycle phase transition GO:1901988 4 0.014
regulation of transferase activity GO:0051338 123 0.014
negative regulation of neurogenesis GO:0050768 78 0.014
gastrulation GO:0007369 2 0.014
response to estrogen GO:0043627 232 0.014
positive regulation of multicellular organismal process GO:0051240 387 0.014
intracellular signal transduction GO:0035556 314 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.014
regulation of peptide secretion GO:0002791 82 0.014
ion transmembrane transport GO:0034220 365 0.014
response to hexose GO:0009746 144 0.013
metal ion transport GO:0030001 289 0.013
cellular lipid metabolic process GO:0044255 208 0.013
negative regulation of transport GO:0051051 136 0.013
lipid biosynthetic process GO:0008610 128 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
cellular response to endogenous stimulus GO:0071495 377 0.013
negative regulation of secretion by cell GO:1903531 72 0.013
hormone transport GO:0009914 121 0.013
circulatory system development GO:0072359 134 0.013
muscle system process GO:0003012 115 0.013
response to lipopolysaccharide GO:0032496 191 0.013
reproductive process GO:0022414 372 0.013
response to metal ion GO:0010038 253 0.013
cellular macromolecule localization GO:0070727 122 0.013
stress activated protein kinase signaling cascade GO:0031098 37 0.013
calcium ion transport GO:0006816 131 0.013
single organism catabolic process GO:0044712 283 0.013
response to growth factor GO:0070848 189 0.013
purine ribonucleotide metabolic process GO:0009150 227 0.013
positive regulation of cell communication GO:0010647 271 0.013
signal release GO:0023061 145 0.012
organic substance catabolic process GO:1901575 316 0.012
negative regulation of phosphate metabolic process GO:0045936 80 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
regulation of neuron differentiation GO:0045664 208 0.012
positive regulation of phosphorylation GO:0042327 177 0.012
response to corticosteroid GO:0031960 235 0.012
negative regulation of cell proliferation GO:0008285 119 0.012
neuron development GO:0048666 286 0.012
brain development GO:0007420 247 0.012
negative regulation of developmental process GO:0051093 125 0.012
purine nucleoside metabolic process GO:0042278 169 0.012
cellular metal ion homeostasis GO:0006875 172 0.012
positive regulation of signaling GO:0023056 270 0.012
amide transport GO:0042886 105 0.012
synaptic transmission GO:0007268 235 0.012
positive regulation of phosphate metabolic process GO:0045937 262 0.012
carbohydrate derivative biosynthetic process GO:1901137 124 0.012
cellular protein localization GO:0034613 122 0.012
response to peptide GO:1901652 292 0.012
insulin secretion GO:0030073 69 0.012
response to glucocorticoid GO:0051384 223 0.012
adult locomotory behavior GO:0008344 4 0.011
negative regulation of secretion GO:0051048 82 0.011
organophosphate catabolic process GO:0046434 148 0.011
peptide hormone secretion GO:0030072 84 0.011
negative regulation of molecular function GO:0044092 133 0.011
aromatic compound catabolic process GO:0019439 168 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
cellular catabolic process GO:0044248 295 0.011
regulation of cell cycle arrest GO:0071156 2 0.011
negative regulation of neuron differentiation GO:0045665 62 0.011
negative regulation of programmed cell death GO:0043069 183 0.011
negative regulation of response to stimulus GO:0048585 155 0.011
cellular response to cytokine stimulus GO:0071345 127 0.011
purine nucleotide metabolic process GO:0006163 229 0.011
peptide secretion GO:0002790 86 0.011
lipid metabolic process GO:0006629 283 0.011
cytoplasmic transport GO:0016482 115 0.011
regulation of phosphate metabolic process GO:0019220 349 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
negative regulation of nervous system development GO:0051961 79 0.011
cellular calcium ion homeostasis GO:0006874 160 0.011
response to wounding GO:0009611 254 0.011
positive regulation of neurogenesis GO:0050769 165 0.011
organonitrogen compound biosynthetic process GO:1901566 167 0.011
calcium ion homeostasis GO:0055074 162 0.011
inorganic cation transmembrane transport GO:0098662 202 0.011
regulation of cell development GO:0060284 263 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
cellular response to hexose stimulus GO:0071331 65 0.011
regeneration GO:0031099 163 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.010
negative regulation of apoptotic process GO:0043066 181 0.010
positive regulation of cell development GO:0010720 176 0.010
response to biotic stimulus GO:0009607 226 0.010
regulation of cellular component organization GO:0051128 368 0.010
positive regulation of phosphorus metabolic process GO:0010562 262 0.010
organic hydroxy compound metabolic process GO:1901615 115 0.010
divalent metal ion transport GO:0070838 132 0.010
cell growth GO:0016049 104 0.010
purine ribonucleoside catabolic process GO:0046130 124 0.010
positive regulation of protein modification process GO:0031401 142 0.010
cytoskeleton organization GO:0007010 111 0.010
gamete generation GO:0007276 124 0.010
catabolic process GO:0009056 351 0.010
regulation of neuron projection development GO:0010975 161 0.010
regulation of insulin secretion GO:0050796 65 0.010
cellular response to hormone stimulus GO:0032870 247 0.010
single organism organelle organization GO:1902589 180 0.010

Setd8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.023
central nervous system disease DOID:331 0 0.010