Rattus norvegicus

0 known processes

Pm20d2

peptidase M20 domain containing 2

(Aliases: Acy1l2)

Pm20d2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 292 0.079
carboxylic acid metabolic process GO:0019752 289 0.074
cell projection organization GO:0030030 302 0.071
neuron differentiation GO:0030182 368 0.060
oxoacid metabolic process GO:0043436 290 0.057
regulation of protein metabolic process GO:0051246 289 0.055
regulation of phosphorylation GO:0042325 248 0.055
anatomical structure morphogenesis GO:0009653 298 0.050
neuron development GO:0048666 286 0.049
response to extracellular stimulus GO:0009991 380 0.048
regulation of cellular component organization GO:0051128 368 0.046
regulation of molecular function GO:0065009 398 0.044
rna metabolic process GO:0016070 406 0.042
response to nutrient levels GO:0031667 370 0.041
transmembrane transport GO:0055085 412 0.041
neuron projection development GO:0031175 273 0.040
cellular amine metabolic process GO:0044106 38 0.039
rna biosynthetic process GO:0032774 380 0.038
regulation of nervous system development GO:0051960 264 0.038
amine metabolic process GO:0009308 38 0.037
regulation of cellular ketone metabolic process GO:0010565 27 0.036
negative regulation of cellular metabolic process GO:0031324 281 0.036
response to nutrient GO:0007584 248 0.036
regulation of nucleic acid templated transcription GO:1903506 380 0.035
cellular ketone metabolic process GO:0042180 51 0.035
regulation of apoptotic process GO:0042981 335 0.034
cellular amino acid metabolic process GO:0006520 107 0.034
organic substance catabolic process GO:1901575 316 0.033
protein phosphorylation GO:0006468 345 0.033
apoptotic process GO:0006915 381 0.032
single organism catabolic process GO:0044712 283 0.032
organelle organization GO:0006996 266 0.032
regulation of cellular amino acid metabolic process GO:0006521 2 0.032
cellular component biogenesis GO:0044085 368 0.032
anion transport GO:0006820 178 0.031
negative regulation of macromolecule metabolic process GO:0010605 260 0.031
regulation of multicellular organismal development GO:2000026 376 0.031
regulation of programmed cell death GO:0043067 341 0.031
regulation of cellular amine metabolic process GO:0033238 8 0.031
reproductive process GO:0022414 372 0.031
response to metal ion GO:0010038 253 0.031
regulation of cell differentiation GO:0045595 320 0.030
cellular response to endogenous stimulus GO:0071495 377 0.030
catabolic process GO:0009056 351 0.030
protein complex assembly GO:0006461 263 0.030
negative regulation of metabolic process GO:0009892 331 0.030
nucleic acid templated transcription GO:0097659 379 0.030
programmed cell death GO:0012501 392 0.029
positive regulation of multicellular organismal process GO:0051240 387 0.028
neuron projection morphogenesis GO:0048812 122 0.028
nucleobase containing small molecule metabolic process GO:0055086 316 0.028
intracellular signal transduction GO:0035556 314 0.028
regulation of signal transduction GO:0009966 318 0.027
response to peptide hormone GO:0043434 278 0.027
regulation of phosphorus metabolic process GO:0051174 349 0.026
regulation of cellular localization GO:0060341 263 0.026
regulation of rna biosynthetic process GO:2001141 381 0.026
central nervous system development GO:0007417 311 0.026
regulation of transcription dna templated GO:0006355 374 0.026
lipid metabolic process GO:0006629 283 0.026
organophosphate metabolic process GO:0019637 370 0.025
negative regulation of signaling GO:0023057 157 0.025
response to estrogen GO:0043627 232 0.025
positive regulation of cellular component organization GO:0051130 200 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.025
macromolecular complex subunit organization GO:0043933 339 0.025
homeostatic process GO:0042592 331 0.024
positive regulation of cell communication GO:0010647 271 0.024
response to carbohydrate GO:0009743 183 0.024
signal release GO:0023061 145 0.024
regulation of phosphate metabolic process GO:0019220 349 0.024
response to ketone GO:1901654 182 0.024
cell projection morphogenesis GO:0048858 123 0.024
reproduction GO:0000003 245 0.024
regulation of rna metabolic process GO:0051252 391 0.024
signal transduction by phosphorylation GO:0023014 144 0.024
cellular response to hormone stimulus GO:0032870 247 0.024
secretion GO:0046903 307 0.024
positive regulation of transport GO:0051050 245 0.023
cation transport GO:0006812 382 0.023
tissue development GO:0009888 252 0.023
multicellular organism reproduction GO:0032504 233 0.023
response to ethanol GO:0045471 162 0.023
positive regulation of cellular biosynthetic process GO:0031328 295 0.023
multicellular organismal reproductive process GO:0048609 233 0.022
negative regulation of gene expression GO:0010629 199 0.022
cell cell signaling GO:0007267 335 0.022
cellular response to stress GO:0033554 269 0.022
multi organism reproductive process GO:0044703 262 0.022
positive regulation of cell proliferation GO:0008284 249 0.022
locomotion GO:0040011 237 0.022
macromolecular complex assembly GO:0065003 273 0.022
response to hexose GO:0009746 144 0.021
regulation of protein phosphorylation GO:0001932 183 0.021
organic anion transport GO:0015711 132 0.021
cellular component morphogenesis GO:0032989 155 0.021
cellular response to oxygen containing compound GO:1901701 386 0.021
regulation of neuron differentiation GO:0045664 208 0.021
protein complex biogenesis GO:0070271 263 0.021
mapk cascade GO:0000165 140 0.021
carbohydrate derivative metabolic process GO:1901135 346 0.021
negative regulation of cell communication GO:0010648 158 0.021
regulation of neurogenesis GO:0050767 247 0.021
response to growth factor GO:0070848 189 0.021
chemical homeostasis GO:0048878 292 0.021
positive regulation of phosphate metabolic process GO:0045937 262 0.020
regulation of system process GO:0044057 208 0.020
response to hypoxia GO:0001666 231 0.020
positive regulation of signaling GO:0023056 270 0.020
response to monosaccharide GO:0034284 159 0.020
macromolecule localization GO:0033036 252 0.020
cellular component movement GO:0006928 248 0.020
response to glucocorticoid GO:0051384 223 0.020
growth GO:0040007 165 0.020
protein complex subunit organization GO:0071822 302 0.019
kidney development GO:0001822 67 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.019
regulation of cellular protein metabolic process GO:0032268 267 0.019
oxidation reduction process GO:0055114 304 0.019
positive regulation of gene expression GO:0010628 244 0.019
regulation of cell projection organization GO:0031344 175 0.019
heart morphogenesis GO:0003007 3 0.019
cellular component assembly GO:0022607 360 0.019
protein localization GO:0008104 191 0.019
single organism organelle organization GO:1902589 180 0.019
positive regulation of cell differentiation GO:0045597 217 0.019
regulation of cell proliferation GO:0042127 359 0.019
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.018
positive regulation of signal transduction GO:0009967 175 0.018
regulation of catalytic activity GO:0050790 304 0.018
cellular catabolic process GO:0044248 295 0.018
cell morphogenesis GO:0000902 142 0.018
cellular homeostasis GO:0019725 252 0.018
response to inorganic substance GO:0010035 377 0.018
single organism reproductive process GO:0044702 297 0.018
blood circulation GO:0008015 183 0.018
lipid biosynthetic process GO:0008610 128 0.018
muscle system process GO:0003012 115 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
response to peptide GO:1901652 292 0.018
cell part morphogenesis GO:0032990 123 0.018
axon development GO:0061564 96 0.018
positive regulation of nucleic acid templated transcription GO:1903508 197 0.017
positive regulation of protein metabolic process GO:0051247 178 0.017
nitrogen compound transport GO:0071705 229 0.017
cellular chemical homeostasis GO:0055082 247 0.017
transcription dna templated GO:0006351 377 0.017
urogenital system development GO:0001655 78 0.017
response to oxygen levels GO:0070482 265 0.017
developmental process involved in reproduction GO:0003006 159 0.017
response to purine containing compound GO:0014074 126 0.017
purine nucleoside metabolic process GO:0042278 169 0.017
positive regulation of developmental process GO:0051094 283 0.017
organonitrogen compound catabolic process GO:1901565 179 0.016
negative regulation of cellular biosynthetic process GO:0031327 161 0.016
negative regulation of protein metabolic process GO:0051248 114 0.016
negative regulation of cellular protein metabolic process GO:0032269 106 0.016
regulation of neuron projection development GO:0010975 161 0.016
inorganic ion transmembrane transport GO:0098660 229 0.016
positive regulation of molecular function GO:0044093 230 0.016
localization of cell GO:0051674 202 0.016
ion homeostasis GO:0050801 212 0.016
regulation of protein modification process GO:0031399 194 0.016
cellular response to lipid GO:0071396 201 0.016
regulation of membrane potential GO:0042391 110 0.016
protein transport GO:0015031 132 0.016
nucleotide metabolic process GO:0009117 279 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
negative regulation of programmed cell death GO:0043069 183 0.016
cellular cation homeostasis GO:0030003 180 0.016
cytosolic calcium ion homeostasis GO:0051480 140 0.016
positive regulation of biosynthetic process GO:0009891 319 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.015
regulation of secretion GO:0051046 224 0.015
single organism biosynthetic process GO:0044711 342 0.015
response to acid chemical GO:0001101 222 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
gland development GO:0048732 155 0.015
regulation of hormone levels GO:0010817 187 0.015
cellular ion homeostasis GO:0006873 184 0.015
cellular response to alcohol GO:0097306 87 0.015
cellular divalent inorganic cation homeostasis GO:0072503 162 0.015
proteolysis GO:0006508 175 0.015
cation transmembrane transport GO:0098655 263 0.015
response to glucose GO:0009749 136 0.015
positive regulation of nervous system development GO:0051962 178 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.015
response to decreased oxygen levels GO:0036293 237 0.015
purine containing compound metabolic process GO:0072521 253 0.015
glycosyl compound metabolic process GO:1901657 182 0.015
chromosome segregation GO:0007059 2 0.015
regulation of intracellular signal transduction GO:1902531 218 0.015
peptidyl amino acid modification GO:0018193 126 0.015
renal system development GO:0072001 67 0.015
negative regulation of cell death GO:0060548 229 0.015
regulation of secretion by cell GO:1903530 208 0.015
cell motility GO:0048870 202 0.014
response to vitamin GO:0033273 131 0.014
hormone secretion GO:0046879 115 0.014
positive regulation of transcription dna templated GO:0045893 197 0.014
positive regulation of cell death GO:0010942 184 0.014
cell morphogenesis involved in differentiation GO:0000904 119 0.014
nucleoside phosphate metabolic process GO:0006753 283 0.014
carboxylic acid transport GO:0046942 115 0.014
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
axonogenesis GO:0007409 71 0.014
dephosphorylation GO:0016311 98 0.014
single organism intracellular transport GO:1902582 166 0.014
organic acid transport GO:0015849 116 0.014
organ morphogenesis GO:0009887 75 0.014
cation homeostasis GO:0055080 195 0.014
negative regulation of molecular function GO:0044092 133 0.014
regulation of canonical wnt signaling pathway GO:0060828 4 0.014
regulation of peptide hormone secretion GO:0090276 80 0.014
cell migration GO:0016477 197 0.014
cellular macromolecule localization GO:0070727 122 0.014
negative regulation of transport GO:0051051 136 0.014
non canonical wnt signaling pathway GO:0035567 3 0.014
axis specification GO:0009798 4 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.014
sexual reproduction GO:0019953 148 0.013
aging GO:0007568 241 0.013
response to corticosteroid GO:0031960 235 0.013
negative regulation of cell differentiation GO:0045596 99 0.013
adult locomotory behavior GO:0008344 4 0.013
calcium ion homeostasis GO:0055074 162 0.013
organic acid biosynthetic process GO:0016053 83 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.013
positive regulation of cellular protein metabolic process GO:0032270 167 0.013
sex differentiation GO:0007548 113 0.013
metal ion homeostasis GO:0055065 186 0.013
divalent inorganic cation transport GO:0072511 134 0.013
carbohydrate metabolic process GO:0005975 130 0.013
positive regulation of fatty acid beta oxidation GO:0032000 4 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
negative regulation of neurogenesis GO:0050768 78 0.013
response to oxidative stress GO:0006979 186 0.013
cellular response to nitrogen compound GO:1901699 210 0.013
monocarboxylic acid metabolic process GO:0032787 152 0.013
gamete generation GO:0007276 124 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
secretion by cell GO:0032940 248 0.013
reproductive system development GO:0061458 128 0.012
peptide transport GO:0015833 97 0.012
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.012
regulation of proteasomal protein catabolic process GO:0061136 4 0.012
brain development GO:0007420 247 0.012
neuronal action potential GO:0019228 35 0.012
cellular response to growth factor stimulus GO:0071363 162 0.012
nucleoside metabolic process GO:0009116 179 0.012
ribose phosphate metabolic process GO:0019693 235 0.012
spermatogenesis GO:0007283 99 0.012
regulation of transferase activity GO:0051338 123 0.012
male gamete generation GO:0048232 99 0.012
regulation of peptide transport GO:0090087 87 0.012
mesoderm development GO:0007498 2 0.012
regulation of hormone secretion GO:0046883 106 0.012
positive regulation of cell development GO:0010720 176 0.012
regulation of cell development GO:0060284 263 0.012
regulation of hydrolase activity GO:0051336 143 0.012
gonad development GO:0008406 104 0.012
ras protein signal transduction GO:0007265 29 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
regulation of reactive oxygen species metabolic process GO:2000377 26 0.012
transcription from rna polymerase ii promoter GO:0006366 252 0.012
reactive oxygen species metabolic process GO:0072593 37 0.012
neurological system process GO:0050877 219 0.012
organic acid catabolic process GO:0016054 49 0.012
enzyme linked receptor protein signaling pathway GO:0007167 116 0.012
cellular lipid metabolic process GO:0044255 208 0.012
regulation of peptide secretion GO:0002791 82 0.011
eye development GO:0001654 50 0.011
metal ion transport GO:0030001 289 0.011
protein oligomerization GO:0051259 191 0.011
small molecule catabolic process GO:0044282 59 0.011
cardiovascular system development GO:0072358 134 0.011
multicellular organismal signaling GO:0035637 44 0.011
ion transmembrane transport GO:0034220 365 0.011
regulation of anatomical structure size GO:0090066 135 0.011
anterior posterior pattern specification GO:0009952 1 0.011
intracellular protein transport GO:0006886 79 0.011
coenzyme metabolic process GO:0006732 86 0.011
head development GO:0060322 247 0.011
positive regulation of rna metabolic process GO:0051254 203 0.011
regulation of kinase activity GO:0043549 117 0.011
reproductive structure development GO:0048608 128 0.011
positive regulation of protein modification process GO:0031401 142 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
cell cycle GO:0007049 101 0.011
cellular response to insulin stimulus GO:0032869 81 0.011
regulation of ion transport GO:0043269 245 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
regeneration GO:0031099 163 0.011
cofactor metabolic process GO:0051186 95 0.011
response to estradiol GO:0032355 164 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
synaptic growth at neuromuscular junction GO:0051124 1 0.011
response to fatty acid GO:0070542 65 0.011
cell growth GO:0016049 104 0.011
positive regulation of apoptotic process GO:0043065 154 0.011
negative regulation of rna biosynthetic process GO:1902679 118 0.011
developmental growth GO:0048589 100 0.011
peptide hormone secretion GO:0030072 84 0.011
establishment of protein localization GO:0045184 141 0.011
amide transport GO:0042886 105 0.011
negative regulation of developmental process GO:0051093 125 0.011
vesicle mediated transport GO:0016192 181 0.011
action potential GO:0001508 54 0.011
synaptic transmission GO:0007268 235 0.011
intracellular transport GO:0046907 185 0.011
negative regulation of cellular component organization GO:0051129 83 0.011
circulatory system process GO:0003013 183 0.011
positive regulation of cell projection organization GO:0031346 111 0.011
acrosome assembly GO:0001675 3 0.011
response to insulin GO:0032868 133 0.010
negative regulation of transcription dna templated GO:0045892 116 0.010
positive regulation of neuron projection development GO:0010976 99 0.010
cell type specific apoptotic process GO:0097285 134 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.010
negative regulation of secretion GO:0051048 82 0.010
actin filament based process GO:0030029 86 0.010
peptide secretion GO:0002790 86 0.010
eye morphogenesis GO:0048592 4 0.010
regulation of protein kinase activity GO:0045859 105 0.010
neural crest cell differentiation GO:0014033 2 0.010
cellular nitrogen compound catabolic process GO:0044270 163 0.010
regulation of cell morphogenesis GO:0022604 77 0.010
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.010
cytoplasmic transport GO:0016482 115 0.010
nucleoside phosphate catabolic process GO:1901292 140 0.010
response to molecule of bacterial origin GO:0002237 194 0.010
regulation of neuron death GO:1901214 115 0.010

Pm20d2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
nervous system disease DOID:863 0 0.040
sensory system disease DOID:0050155 0 0.015
central nervous system disease DOID:331 0 0.013