Rattus norvegicus

0 known processes

Nlrx1

NLR family member X1

(Aliases: RGD1311293)

Nlrx1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
intracellular signal transduction GO:0035556 314 0.112
Mouse
oxoacid metabolic process GO:0043436 290 0.104
regulation of cell proliferation GO:0042127 359 0.083
protein phosphorylation GO:0006468 345 0.062
carboxylic acid metabolic process GO:0019752 289 0.060
organic acid metabolic process GO:0006082 292 0.054
response to nutrient levels GO:0031667 370 0.051
response to extracellular stimulus GO:0009991 380 0.047
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.046
chemical homeostasis GO:0048878 292 0.045
regulation of signal transduction GO:0009966 318 0.044
Mouse
cellular amino acid metabolic process GO:0006520 107 0.043
organophosphate metabolic process GO:0019637 370 0.043
regulation of cellular protein metabolic process GO:0032268 267 0.041
response to peptide hormone GO:0043434 278 0.041
regulation of cell differentiation GO:0045595 320 0.039
nucleobase containing small molecule metabolic process GO:0055086 316 0.039
cellular homeostasis GO:0019725 252 0.039
cellular chemical homeostasis GO:0055082 247 0.038
positive regulation of gene expression GO:0010628 244 0.038
rna biosynthetic process GO:0032774 380 0.037
cation transport GO:0006812 382 0.037
lipid metabolic process GO:0006629 283 0.037
cation homeostasis GO:0055080 195 0.037
response to peptide GO:1901652 292 0.037
response to nutrient GO:0007584 248 0.036
locomotion GO:0040011 237 0.036
negative regulation of cell communication GO:0010648 158 0.036
Mouse
positive regulation of cell proliferation GO:0008284 249 0.036
regulation of cellular ketone metabolic process GO:0010565 27 0.035
positive regulation of cellular biosynthetic process GO:0031328 295 0.034
cellular response to oxygen containing compound GO:1901701 386 0.034
cellular amine metabolic process GO:0044106 38 0.033
cellular ketone metabolic process GO:0042180 51 0.033
catabolic process GO:0009056 351 0.033
negative regulation of cell proliferation GO:0008285 119 0.032
anatomical structure morphogenesis GO:0009653 298 0.032
transcription dna templated GO:0006351 377 0.032
regulation of multicellular organismal development GO:2000026 376 0.032
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.032
regulation of cellular amino acid metabolic process GO:0006521 2 0.031
carbohydrate derivative metabolic process GO:1901135 346 0.031
regulation of cell development GO:0060284 263 0.031
reproductive process GO:0022414 372 0.030
homeostatic process GO:0042592 331 0.030
regulation of phosphorus metabolic process GO:0051174 349 0.030
transmembrane transport GO:0055085 412 0.030
regulation of rna metabolic process GO:0051252 391 0.030
cellular response to stress GO:0033554 269 0.030
regulation of system process GO:0044057 208 0.030
regulation of programmed cell death GO:0043067 341 0.030
apoptotic process GO:0006915 381 0.029
nucleotide metabolic process GO:0009117 279 0.029
regulation of apoptotic process GO:0042981 335 0.029
metal ion transport GO:0030001 289 0.028
single organism biosynthetic process GO:0044711 342 0.028
regulation of molecular function GO:0065009 398 0.028
positive regulation of phosphorus metabolic process GO:0010562 262 0.028
amine metabolic process GO:0009308 38 0.028
cellular metal ion homeostasis GO:0006875 172 0.027
central nervous system development GO:0007417 311 0.027
cellular cation homeostasis GO:0030003 180 0.027
positive regulation of phosphate metabolic process GO:0045937 262 0.027
cellular response to nitrogen compound GO:1901699 210 0.027
single organism catabolic process GO:0044712 283 0.027
negative regulation of gene expression GO:0010629 199 0.027
regulation of phosphate metabolic process GO:0019220 349 0.027
cellular response to cytokine stimulus GO:0071345 127 0.027
regulation of protein metabolic process GO:0051246 289 0.027
regulation of catalytic activity GO:0050790 304 0.027
nucleic acid templated transcription GO:0097659 379 0.027
metal ion homeostasis GO:0055065 186 0.027
negative regulation of multicellular organismal process GO:0051241 203 0.027
Mouse
regulation of nervous system development GO:0051960 264 0.026
response to inorganic substance GO:0010035 377 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.026
regulation of nucleic acid templated transcription GO:1903506 380 0.026
single organism reproductive process GO:0044702 297 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
Mouse
regulation of rna biosynthetic process GO:2001141 381 0.025
regulation of neurogenesis GO:0050767 247 0.025
ion transmembrane transport GO:0034220 365 0.025
rna metabolic process GO:0016070 406 0.024
cell cell signaling GO:0007267 335 0.024
regulation of transcription dna templated GO:0006355 374 0.024
negative regulation of metabolic process GO:0009892 331 0.024
regulation of phosphorylation GO:0042325 248 0.024
circulatory system process GO:0003013 183 0.024
organic substance catabolic process GO:1901575 316 0.024
cellular response to hormone stimulus GO:0032870 247 0.023
protein oligomerization GO:0051259 191 0.023
positive regulation of signaling GO:0023056 270 0.023
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.023
regulation of protein modification process GO:0031399 194 0.023
ion homeostasis GO:0050801 212 0.023
negative regulation of signaling GO:0023057 157 0.023
Mouse
blood circulation GO:0008015 183 0.023
small gtpase mediated signal transduction GO:0007264 36 0.023
cell morphogenesis involved in differentiation GO:0000904 119 0.023
positive regulation of multicellular organismal process GO:0051240 387 0.023
Mouse
ribose phosphate metabolic process GO:0019693 235 0.022
response to metal ion GO:0010038 253 0.022
response to estrogen GO:0043627 232 0.022
positive regulation of cellular amine metabolic process GO:0033240 3 0.022
multi organism reproductive process GO:0044703 262 0.022
regulation of membrane potential GO:0042391 110 0.022
secretion GO:0046903 307 0.022
negative regulation of cellular metabolic process GO:0031324 281 0.022
cellular ion homeostasis GO:0006873 184 0.022
positive regulation of transcription dna templated GO:0045893 197 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.021
carbohydrate metabolic process GO:0005975 130 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
regulation of neuron differentiation GO:0045664 208 0.021
cell projection organization GO:0030030 302 0.021
purine ribonucleotide metabolic process GO:0009150 227 0.021
cellular catabolic process GO:0044248 295 0.021
synaptic transmission GO:0007268 235 0.021
divalent inorganic cation homeostasis GO:0072507 165 0.021
neuron projection development GO:0031175 273 0.021
negative regulation of apoptotic process GO:0043066 181 0.021
cellular divalent inorganic cation homeostasis GO:0072503 162 0.020
positive regulation of biosynthetic process GO:0009891 319 0.020
cell migration GO:0016477 197 0.020
purine nucleotide metabolic process GO:0006163 229 0.020
negative regulation of macromolecule metabolic process GO:0010605 260 0.020
carbohydrate derivative biosynthetic process GO:1901137 124 0.020
localization of cell GO:0051674 202 0.020
positive regulation of cell differentiation GO:0045597 217 0.020
positive regulation of cellular protein metabolic process GO:0032270 167 0.019
response to estradiol GO:0032355 164 0.019
organelle organization GO:0006996 266 0.019
ribonucleotide metabolic process GO:0009259 231 0.019
purine containing compound metabolic process GO:0072521 253 0.019
programmed cell death GO:0012501 392 0.019
regulation of protein phosphorylation GO:0001932 183 0.019
response to growth factor GO:0070848 189 0.019
circulatory system development GO:0072359 134 0.019
positive regulation of cell communication GO:0010647 271 0.019
regulation of response to stress GO:0080134 126 0.019
Mouse
cellular response to endogenous stimulus GO:0071495 377 0.018
negative regulation of cell death GO:0060548 229 0.018
regulation of kinase activity GO:0043549 117 0.018
response to ketone GO:1901654 182 0.018
protein complex biogenesis GO:0070271 263 0.018
secretion by cell GO:0032940 248 0.018
regulation of cellular localization GO:0060341 263 0.018
peptidyl amino acid modification GO:0018193 126 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.018
regulation of cellular component organization GO:0051128 368 0.018
positive regulation of nervous system development GO:0051962 178 0.018
positive regulation of rna metabolic process GO:0051254 203 0.018
eye morphogenesis GO:0048592 4 0.018
female pregnancy GO:0007565 122 0.017
heterocycle catabolic process GO:0046700 167 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.017
positive regulation of developmental process GO:0051094 283 0.017
reproduction GO:0000003 245 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.017
regulation of nucleotide metabolic process GO:0006140 117 0.017
neuron development GO:0048666 286 0.017
nucleoside phosphate biosynthetic process GO:1901293 102 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
response to glucocorticoid GO:0051384 223 0.016
retina morphogenesis in camera type eye GO:0060042 1 0.016
growth GO:0040007 165 0.016
response to decreased oxygen levels GO:0036293 237 0.016
positive regulation of neurogenesis GO:0050769 165 0.016
positive regulation of transport GO:0051050 245 0.016
cellular lipid metabolic process GO:0044255 208 0.016
cell morphogenesis GO:0000902 142 0.016
response to vitamin GO:0033273 131 0.016
reproductive structure development GO:0048608 128 0.016
cellular nitrogen compound catabolic process GO:0044270 163 0.016
cellular calcium ion homeostasis GO:0006874 160 0.016
response to acid chemical GO:0001101 222 0.016
single organism carbohydrate metabolic process GO:0044723 118 0.016
positive regulation of molecular function GO:0044093 230 0.016
negative regulation of cellular biosynthetic process GO:0031327 161 0.016
camera type eye morphogenesis GO:0048593 2 0.016
cellular component movement GO:0006928 248 0.016
multicellular organismal reproductive process GO:0048609 233 0.016
proteolysis GO:0006508 175 0.016
tissue development GO:0009888 252 0.016
response to carbohydrate GO:0009743 183 0.016
negative regulation of transport GO:0051051 136 0.016
positive regulation of protein metabolic process GO:0051247 178 0.016
multicellular organism reproduction GO:0032504 233 0.016
transcription from rna polymerase ii promoter GO:0006366 252 0.016
organophosphate biosynthetic process GO:0090407 143 0.016
purine nucleotide biosynthetic process GO:0006164 83 0.016
regulation of intracellular signal transduction GO:1902531 218 0.016
Mouse
positive regulation of protein modification process GO:0031401 142 0.016
heart morphogenesis GO:0003007 3 0.016
response to oxygen levels GO:0070482 265 0.015
negative regulation of response to stimulus GO:0048585 155 0.015
Mouse
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.015
organonitrogen compound biosynthetic process GO:1901566 167 0.015
cellular response to growth factor stimulus GO:0071363 162 0.015
response to ethanol GO:0045471 162 0.015
response to glucose GO:0009749 136 0.015
regulation of hormone levels GO:0010817 187 0.015
sexual reproduction GO:0019953 148 0.015
regulation of canonical wnt signaling pathway GO:0060828 4 0.015
positive regulation of cellular component organization GO:0051130 200 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
ras protein signal transduction GO:0007265 29 0.015
nucleoside metabolic process GO:0009116 179 0.015
regulation of cellular component movement GO:0051270 150 0.015
response to organophosphorus GO:0046683 102 0.015
regulation of transferase activity GO:0051338 123 0.015
regulation of cellular catabolic process GO:0031329 101 0.015
gland development GO:0048732 155 0.014
gastrulation GO:0007369 2 0.014
macromolecular complex assembly GO:0065003 273 0.014
multicellular organismal signaling GO:0035637 44 0.014
inorganic ion transmembrane transport GO:0098660 229 0.014
cellular component assembly GO:0022607 360 0.014
purine nucleoside metabolic process GO:0042278 169 0.014
cardiac chamber development GO:0003205 1 0.014
single organism behavior GO:0044708 130 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.014
protein complex subunit organization GO:0071822 302 0.014
response to hypoxia GO:0001666 231 0.014
regulation of secretion by cell GO:1903530 208 0.014
negative regulation of programmed cell death GO:0043069 183 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.014
monosaccharide metabolic process GO:0005996 61 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
muscle cell proliferation GO:0033002 84 0.014
signal transduction by phosphorylation GO:0023014 144 0.014
macromolecular complex subunit organization GO:0043933 339 0.014
regulation of cell projection organization GO:0031344 175 0.014
regulation of smooth muscle cell proliferation GO:0048660 75 0.014
macromolecule localization GO:0033036 252 0.014
positive regulation of protein phosphorylation GO:0001934 135 0.014
protein complex assembly GO:0006461 263 0.014
purine ribonucleoside catabolic process GO:0046130 124 0.014
signal release GO:0023061 145 0.014
negative regulation of biosynthetic process GO:0009890 168 0.014
smooth muscle cell proliferation GO:0048659 77 0.014
anion transport GO:0006820 178 0.014
monovalent inorganic cation transport GO:0015672 172 0.013
aromatic compound catabolic process GO:0019439 168 0.013
positive regulation of phosphorylation GO:0042327 177 0.013
response to cytokine GO:0034097 215 0.013
response to oxidative stress GO:0006979 186 0.013
single organism organelle organization GO:1902589 180 0.013
rhythmic process GO:0048511 156 0.013
cellular response to peptide GO:1901653 133 0.013
regeneration GO:0031099 163 0.013
developmental process involved in reproduction GO:0003006 159 0.013
nitrogen compound transport GO:0071705 229 0.013
negative regulation of molecular function GO:0044092 133 0.013
embryonic pattern specification GO:0009880 1 0.013
organic anion transport GO:0015711 132 0.013
chromosome segregation GO:0007059 2 0.013
response to insulin GO:0032868 133 0.013
positive regulation of neuron differentiation GO:0045666 126 0.013
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
adult locomotory behavior GO:0008344 4 0.013
regulation of blood circulation GO:1903522 110 0.013
axis specification GO:0009798 4 0.013
positive regulation of signal transduction GO:0009967 175 0.013
head development GO:0060322 247 0.013
cation transmembrane transport GO:0098655 263 0.013
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.013
calcium ion homeostasis GO:0055074 162 0.013
regulation of ion transport GO:0043269 245 0.013
regulation of blood pressure GO:0008217 83 0.013
positive regulation of nucleotide metabolic process GO:0045981 91 0.013
neuron differentiation GO:0030182 368 0.013
negative regulation of rna biosynthetic process GO:1902679 118 0.013
oxidation reduction process GO:0055114 304 0.013
inorganic cation transmembrane transport GO:0098662 202 0.013
response to camp GO:0051591 91 0.013
regulation of cell motility GO:2000145 131 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
monocarboxylic acid metabolic process GO:0032787 152 0.012
muscle system process GO:0003012 115 0.012
neurological system process GO:0050877 219 0.012
response to monosaccharide GO:0034284 159 0.012
neuron projection morphogenesis GO:0048812 122 0.012
cardiovascular system development GO:0072358 134 0.012
regulation of catabolic process GO:0009894 113 0.012
regulation of protein kinase activity GO:0045859 105 0.012
aging GO:0007568 241 0.012
cell growth GO:0016049 104 0.012
response to purine containing compound GO:0014074 126 0.012
skeletal system development GO:0001501 41 0.012
negative regulation of transcription dna templated GO:0045892 116 0.012
cell motility GO:0048870 202 0.012
jak stat cascade GO:0007259 26 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
response to hexose GO:0009746 144 0.012
response to corticosteroid GO:0031960 235 0.012
regulation of growth GO:0040008 105 0.012
response to reactive oxygen species GO:0000302 120 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
organophosphate catabolic process GO:0046434 148 0.012
positive regulation of intracellular signal transduction GO:1902533 138 0.012
regulation of neuron projection development GO:0010975 161 0.011
cyclic nucleotide biosynthetic process GO:0009190 63 0.011
positive regulation of cell development GO:0010720 176 0.011
positive regulation of cell death GO:0010942 184 0.011
lipid storage GO:0019915 1 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
ribonucleotide biosynthetic process GO:0009260 85 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
nucleoside phosphate catabolic process GO:1901292 140 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
brain development GO:0007420 247 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
regulation of secretion GO:0051046 224 0.011
negative regulation of cell differentiation GO:0045596 99 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
positive regulation of catabolic process GO:0009896 78 0.011
behavior GO:0007610 205 0.011
response to bacterium GO:0009617 200 0.011
hormone secretion GO:0046879 115 0.011
purine containing compound catabolic process GO:0072523 138 0.011
multicellular organism growth GO:0035264 1 0.011
negative regulation of rna metabolic process GO:0051253 123 0.011
cellular component biogenesis GO:0044085 368 0.011
ossification GO:0001503 70 0.011
regulation of peptide secretion GO:0002791 82 0.011
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.011
response to radiation GO:0009314 137 0.011
negative regulation of cellular protein metabolic process GO:0032269 106 0.011
mapk cascade GO:0000165 140 0.011
cellular response to lipid GO:0071396 201 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
hexose metabolic process GO:0019318 58 0.011
response to biotic stimulus GO:0009607 226 0.011
Mouse
organ morphogenesis GO:0009887 75 0.011
regulation of synaptic transmission GO:0050804 141 0.011
actin filament based process GO:0030029 86 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 72 0.010
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.010
cellular carbohydrate metabolic process GO:0044262 72 0.010
action potential GO:0001508 54 0.010
negative regulation of secretion GO:0051048 82 0.010
cellular component morphogenesis GO:0032989 155 0.010
g protein coupled receptor signaling pathway GO:0007186 242 0.010
regulation of lipid metabolic process GO:0019216 68 0.010
sex differentiation GO:0007548 113 0.010
regulation of neuron death GO:1901214 115 0.010
regulation of anatomical structure size GO:0090066 135 0.010
regulation of ion transmembrane transport GO:0034765 121 0.010
response to mechanical stimulus GO:0009612 134 0.010
ribonucleoside triphosphate metabolic process GO:0009199 141 0.010
rho protein signal transduction GO:0007266 11 0.010
ribonucleoside triphosphate catabolic process GO:0009203 122 0.010
ribose phosphate biosynthetic process GO:0046390 87 0.010

Nlrx1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.061
musculoskeletal system disease DOID:17 0 0.061
nervous system disease DOID:863 0 0.020
connective tissue disease DOID:65 0 0.018
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.016
bone disease DOID:0080001 0 0.013
sensory system disease DOID:0050155 0 0.012
muscular disease DOID:0080000 0 0.011
central nervous system disease DOID:331 0 0.010