Rattus norvegicus

0 known processes

Cst12

cystatin 12

Cst12 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chemical homeostasis GO:0048878 292 0.238
homeostatic process GO:0042592 331 0.224
organic acid metabolic process GO:0006082 292 0.219
tissue development GO:0009888 252 0.159
Rat
cellular response to endogenous stimulus GO:0071495 377 0.149
development of primary sexual characteristics GO:0045137 107 0.144
Rat
calcium ion homeostasis GO:0055074 162 0.134
transmembrane transport GO:0055085 412 0.128
single organism biosynthetic process GO:0044711 342 0.123
response to inorganic substance GO:0010035 377 0.122
Rat
ion transmembrane transport GO:0034220 365 0.120
alcohol metabolic process GO:0006066 77 0.112
single organism behavior GO:0044708 130 0.112
Rat
cellular ion homeostasis GO:0006873 184 0.109
cellular metal ion homeostasis GO:0006875 172 0.109
oxoacid metabolic process GO:0043436 290 0.108
cellular chemical homeostasis GO:0055082 247 0.102
cell cell signaling GO:0007267 335 0.101
regulation of cell proliferation GO:0042127 359 0.099
Rat
carboxylic acid metabolic process GO:0019752 289 0.090
fractalkine metabolic process GO:0050756 3 0.089
response to extracellular stimulus GO:0009991 380 0.088
Rat
blood circulation GO:0008015 183 0.084
cellular response to hormone stimulus GO:0032870 247 0.079
cellular divalent inorganic cation homeostasis GO:0072503 162 0.079
behavior GO:0007610 205 0.076
Rat
glycerolipid metabolic process GO:0046486 67 0.073
anatomical structure morphogenesis GO:0009653 298 0.073
response to ketone GO:1901654 182 0.070
localization of cell GO:0051674 202 0.067
regulation of ion transport GO:0043269 245 0.065
cellular component assembly GO:0022607 360 0.064
amine metabolic process GO:0009308 38 0.063
response to acid chemical GO:0001101 222 0.063
negative regulation of ion transport GO:0043271 51 0.061
organonitrogen compound biosynthetic process GO:1901566 167 0.060
circulatory system process GO:0003013 183 0.058
cellular response to peptide GO:1901653 133 0.058
cellular response to growth factor stimulus GO:0071363 162 0.058
camp metabolic process GO:0046058 63 0.058
response to decreased oxygen levels GO:0036293 237 0.057
Rat
inorganic cation transmembrane transport GO:0098662 202 0.055
response to peptide GO:1901652 292 0.055
ethanolamine containing compound metabolic process GO:0042439 14 0.055
regulation of hormone levels GO:0010817 187 0.054
regulation of epithelial cell proliferation GO:0050678 49 0.054
response to peptide hormone GO:0043434 278 0.053
response to lipopolysaccharide GO:0032496 191 0.052
nitrogen compound transport GO:0071705 229 0.051
negative regulation of cellular metabolic process GO:0031324 281 0.051
Rat
cellular response to oxygen containing compound GO:1901701 386 0.051
Rat
reproductive system development GO:0061458 128 0.051
Rat
regulation of body fluid levels GO:0050878 90 0.050
sex differentiation GO:0007548 113 0.050
Rat
cellular homeostasis GO:0019725 252 0.050
cellular cation homeostasis GO:0030003 180 0.050
developmental induction GO:0031128 2 0.049
multicellular organismal homeostasis GO:0048871 49 0.049
positive regulation of transport GO:0051050 245 0.048
regulation of sodium ion transmembrane transporter activity GO:2000649 4 0.048
positive regulation of cell proliferation GO:0008284 249 0.048
Rat
macromolecular complex subunit organization GO:0043933 339 0.048
regulation of organ formation GO:0003156 2 0.047
cellular calcium ion homeostasis GO:0006874 160 0.047
cytosolic calcium ion homeostasis GO:0051480 140 0.046
protein complex assembly GO:0006461 263 0.046
positive regulation of signaling GO:0023056 270 0.045
hormone secretion GO:0046879 115 0.045
regulation of peptide hormone secretion GO:0090276 80 0.045
regulation of homeostatic process GO:0032844 101 0.044
neuron differentiation GO:0030182 368 0.044
reproductive structure development GO:0048608 128 0.043
Rat
organic hydroxy compound metabolic process GO:1901615 115 0.042
positive regulation of developmental process GO:0051094 283 0.042
cellular ketone metabolic process GO:0042180 51 0.041
protein complex subunit organization GO:0071822 302 0.040
lipid biosynthetic process GO:0008610 128 0.040
response to radiation GO:0009314 137 0.040
regulation of immune system process GO:0002682 123 0.040
developmental process involved in reproduction GO:0003006 159 0.039
Rat
response to nutrient levels GO:0031667 370 0.039
Rat
divalent inorganic cation homeostasis GO:0072507 165 0.039
response to external biotic stimulus GO:0043207 221 0.039
Rat
multicellular organism reproduction GO:0032504 233 0.039
inorganic ion transmembrane transport GO:0098660 229 0.039
cellular response to lipid GO:0071396 201 0.038
regulation of programmed cell death GO:0043067 341 0.038
Rat
cellular amine metabolic process GO:0044106 38 0.038
cellular lipid metabolic process GO:0044255 208 0.038
response to molecule of bacterial origin GO:0002237 194 0.038
neurological system process GO:0050877 219 0.037
reproduction GO:0000003 245 0.037
regulation of system process GO:0044057 208 0.037
gonad development GO:0008406 104 0.036
Rat
g protein coupled receptor signaling pathway GO:0007186 242 0.036
reproductive process GO:0022414 372 0.036
Rat
organophosphate metabolic process GO:0019637 370 0.036
renal filtration GO:0097205 10 0.035
cation homeostasis GO:0055080 195 0.035
cation transport GO:0006812 382 0.034
response to other organism GO:0051707 220 0.034
Rat
purine ribonucleotide metabolic process GO:0009150 227 0.034
angiogenesis involved in coronary vascular morphogenesis GO:0060978 3 0.033
regulation of cellular ketone metabolic process GO:0010565 27 0.033
peptide secretion GO:0002790 86 0.032
organic anion transport GO:0015711 132 0.032
metal ion homeostasis GO:0055065 186 0.032
muscle cell proliferation GO:0033002 84 0.031
response to fibroblast growth factor GO:0071774 29 0.031
multi organism reproductive process GO:0044703 262 0.031
Rat
regulation of behavior GO:0050795 61 0.031
cellular response to stress GO:0033554 269 0.030
Rat
single organism reproductive process GO:0044702 297 0.030
Rat
protein complex biogenesis GO:0070271 263 0.030
metal ion transport GO:0030001 289 0.030
sodium ion transmembrane transport GO:0035725 67 0.029
organelle organization GO:0006996 266 0.029
negative regulation of metabolic process GO:0009892 331 0.029
Rat
male gonad development GO:0008584 59 0.029
Rat
regulation of peptide transport GO:0090087 87 0.028
regulation of peptide secretion GO:0002791 82 0.028
regulation of multicellular organismal development GO:2000026 376 0.028
alcohol biosynthetic process GO:0046165 38 0.028
small molecule biosynthetic process GO:0044283 124 0.028
heart development GO:0007507 72 0.028
regulation of cellular protein metabolic process GO:0032268 267 0.028
Rat
response to oxygen levels GO:0070482 265 0.027
Rat
circulatory system development GO:0072359 134 0.027
learning or memory GO:0007611 90 0.027
lipid metabolic process GO:0006629 283 0.027
positive regulation of molecular function GO:0044093 230 0.027
response to growth factor GO:0070848 189 0.027
phenol containing compound metabolic process GO:0018958 30 0.027
sexual reproduction GO:0019953 148 0.027
ion homeostasis GO:0050801 212 0.027
cellular response to lipopolysaccharide GO:0071222 55 0.027
epithelial cell proliferation GO:0050673 54 0.027
positive regulation of response to external stimulus GO:0032103 51 0.026
regulation of phosphate metabolic process GO:0019220 349 0.026
macromolecule localization GO:0033036 252 0.026
response to corticosteroid GO:0031960 235 0.026
mapk cascade GO:0000165 140 0.026
regulation of phosphorylation GO:0042325 248 0.025
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.025
regulation of response to stress GO:0080134 126 0.025
positive regulation of multicellular organismal process GO:0051240 387 0.025
defense response GO:0006952 194 0.025
response to carbohydrate GO:0009743 183 0.025
Rat
organ induction GO:0001759 1 0.025
signal release GO:0023061 145 0.025
sensory perception GO:0007600 101 0.024
response to insulin GO:0032868 133 0.024
insulin secretion GO:0030073 69 0.024
regulation of cellular amino acid metabolic process GO:0006521 2 0.024
vitamin d metabolic process GO:0042359 4 0.024
immune system process GO:0002376 204 0.024
leydig cell differentiation GO:0033327 8 0.024
positive regulation of response to stimulus GO:0048584 285 0.024
regulation of hormone secretion GO:0046883 106 0.024
inflammatory response GO:0006954 150 0.024
development of primary male sexual characteristics GO:0046546 59 0.023
Rat
cellular component biogenesis GO:0044085 368 0.023
cellular biogenic amine metabolic process GO:0006576 30 0.023
protein phosphorylation GO:0006468 345 0.023
anion transport GO:0006820 178 0.023
regulation of smooth muscle cell proliferation GO:0048660 75 0.023
gland development GO:0048732 155 0.023
Rat
cell morphogenesis GO:0000902 142 0.023
nucleobase containing small molecule metabolic process GO:0055086 316 0.023
rna metabolic process GO:0016070 406 0.023
regulation of molecular function GO:0065009 398 0.023
Rat
multicellular organismal reproductive process GO:0048609 233 0.022
cellular component movement GO:0006928 248 0.022
secretion GO:0046903 307 0.022
regulation of blood pressure GO:0008217 83 0.021
response to ionizing radiation GO:0010212 59 0.021
response to glucocorticoid GO:0051384 223 0.021
organophosphate biosynthetic process GO:0090407 143 0.021
testosterone biosynthetic process GO:0061370 5 0.021
aging GO:0007568 241 0.021
nucleoside phosphate metabolic process GO:0006753 283 0.021
regulation of cellular component movement GO:0051270 150 0.021
regulation of secretion GO:0051046 224 0.021
response to estrogen GO:0043627 232 0.021
Rat
positive regulation of peptide hormone secretion GO:0090277 50 0.021
cellular response to organic cyclic compound GO:0071407 202 0.021
positive regulation of cell communication GO:0010647 271 0.021
response to metal ion GO:0010038 253 0.021
intracellular signal transduction GO:0035556 314 0.021
carbohydrate derivative metabolic process GO:1901135 346 0.021
intracellular transport GO:0046907 185 0.021
response to hypoxia GO:0001666 231 0.020
Rat
regulation of insulin secretion GO:0050796 65 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
Rat
signal transduction by phosphorylation GO:0023014 144 0.020
regulation of metal ion transport GO:0010959 118 0.020
central nervous system development GO:0007417 311 0.020
Rat
cell projection organization GO:0030030 302 0.020
cellular response to tumor necrosis factor GO:0071356 46 0.020
purine containing compound metabolic process GO:0072521 253 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.020
Rat
muscle system process GO:0003012 115 0.020
ribose phosphate metabolic process GO:0019693 235 0.020
locomotion GO:0040011 237 0.020
regulation of apoptotic process GO:0042981 335 0.020
regulation of phosphorus metabolic process GO:0051174 349 0.020
female sex differentiation GO:0046660 59 0.019
response to nicotine GO:0035094 51 0.019
purine ribonucleotide biosynthetic process GO:0009152 81 0.019
positive regulation of secretion by cell GO:1903532 128 0.019
cellular component morphogenesis GO:0032989 155 0.019
cell projection morphogenesis GO:0048858 123 0.019
maintenance of location GO:0051235 17 0.019
cellular amino acid metabolic process GO:0006520 107 0.019
coronary vasculature morphogenesis GO:0060977 3 0.019
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 51 0.019
neuron death GO:0070997 127 0.019
tube development GO:0035295 89 0.018
regulation of blood circulation GO:1903522 110 0.018
ovulation cycle GO:0042698 67 0.018
response to amino acid GO:0043200 75 0.018
response to antibiotic GO:0046677 39 0.018
Rat
response to transition metal nanoparticle GO:1990267 122 0.018
Rat
chemokine metabolic process GO:0050755 3 0.018
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 2 0.018
single organism intracellular transport GO:1902582 166 0.018
divalent inorganic cation transport GO:0072511 134 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
positive regulation of intracellular signal transduction GO:1902533 138 0.018
ribonucleotide biosynthetic process GO:0009260 85 0.017
positive regulation of biosynthetic process GO:0009891 319 0.017
Rat
hormone transport GO:0009914 121 0.017
ovulation cycle process GO:0022602 50 0.017
amide transport GO:0042886 105 0.017
specification of organ identity GO:0010092 2 0.017
male sex differentiation GO:0046661 64 0.017
Rat
response to reactive oxygen species GO:0000302 120 0.017
Rat
regulation of signal transduction GO:0009966 318 0.017
response to bacterium GO:0009617 200 0.017
apoptotic process GO:0006915 381 0.017
Rat
regulation of cell differentiation GO:0045595 320 0.017
vascular process in circulatory system GO:0003018 96 0.017
sequestering of calcium ion GO:0051208 8 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.017
response to transforming growth factor beta GO:0071559 46 0.016
regulation of transmembrane transport GO:0034762 122 0.016
negative regulation of transport GO:0051051 136 0.016
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 27 0.016
cytoplasmic transport GO:0016482 115 0.016
cytoskeleton organization GO:0007010 111 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
positive regulation of rna biosynthetic process GO:1902680 197 0.016
response to dexamethasone GO:0071548 49 0.016
peptide hormone secretion GO:0030072 84 0.016
negative regulation of macromolecule metabolic process GO:0010605 260 0.016
Rat
development of primary female sexual characteristics GO:0046545 56 0.016
organic hydroxy compound biosynthetic process GO:1901617 51 0.016
limbic system development GO:0021761 38 0.016
steroid biosynthetic process GO:0006694 48 0.016
positive regulation of phosphate metabolic process GO:0045937 262 0.016
sensory perception of pain GO:0019233 73 0.015
heart contraction GO:0060047 57 0.015
endoplasmic reticulum to cytosol transport GO:1903513 4 0.015
regulation of anatomical structure size GO:0090066 135 0.015
response to ethanol GO:0045471 162 0.015
regulation of defense response GO:0031347 68 0.015
peptide transport GO:0015833 97 0.015
response to hexose GO:0009746 144 0.015
muscle contraction GO:0006936 88 0.015
multi multicellular organism process GO:0044706 138 0.015
Rat
regulation of membrane potential GO:0042391 110 0.015
regulation of tube size GO:0035150 89 0.015
positive regulation of apoptotic process GO:0043065 154 0.015
single organism catabolic process GO:0044712 283 0.015
glycerophospholipid metabolic process GO:0006650 47 0.015
ossification GO:0001503 70 0.015
macromolecular complex assembly GO:0065003 273 0.015
positive regulation of ion transport GO:0043270 94 0.015
maternal process involved in female pregnancy GO:0060135 38 0.015
nucleotide metabolic process GO:0009117 279 0.014
cellular response to external stimulus GO:0071496 118 0.014
glomerular filtration GO:0003094 10 0.014
negative regulation of cell communication GO:0010648 158 0.014
single organism organelle organization GO:1902589 180 0.014
single organism carbohydrate metabolic process GO:0044723 118 0.014
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
carbohydrate biosynthetic process GO:0016051 42 0.014
cyclic nucleotide biosynthetic process GO:0009190 63 0.014
response to nutrient GO:0007584 248 0.014
cellular response to molecule of bacterial origin GO:0071219 56 0.014
heart process GO:0003015 57 0.014
positive regulation of signal transduction GO:0009967 175 0.014
regulation of carbohydrate metabolic process GO:0006109 41 0.014
cardiovascular system development GO:0072358 134 0.014
positive regulation of cellular biosynthetic process GO:0031328 295 0.014
Rat
positive regulation of mapk cascade GO:0043410 92 0.014
regulation of ion homeostasis GO:2000021 63 0.014
regulation of action potential GO:0098900 14 0.014
smooth muscle cell proliferation GO:0048659 77 0.013
cellular response to organonitrogen compound GO:0071417 197 0.013
positive regulation of cardiac muscle cell proliferation GO:0060045 4 0.013
protein localization GO:0008104 191 0.013
transcription from rna polymerase ii promoter GO:0006366 252 0.013
regulation of camp biosynthetic process GO:0030817 38 0.013
jnk cascade GO:0007254 28 0.013
positive regulation of cell differentiation GO:0045597 217 0.013
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.013
single organism cellular localization GO:1902580 102 0.013
actin filament based process GO:0030029 86 0.013
purine nucleotide biosynthetic process GO:0006164 83 0.013
cellular response to glucocorticoid stimulus GO:0071385 68 0.013
cellular response to mechanical stimulus GO:0071260 48 0.013
peptidyl amino acid modification GO:0018193 126 0.013
cellular response to transforming growth factor beta stimulus GO:0071560 41 0.013
synaptic transmission GO:0007268 235 0.013
nucleotide biosynthetic process GO:0009165 98 0.013
female pregnancy GO:0007565 122 0.013
Rat
regulation of ion transmembrane transport GO:0034765 121 0.013
purine nucleotide metabolic process GO:0006163 229 0.013
cellular carbohydrate metabolic process GO:0044262 72 0.013
cell cell signaling involved in cell fate commitment GO:0045168 2 0.012
organ formation GO:0048645 3 0.012
cellular response to corticosteroid stimulus GO:0071384 69 0.012
positive regulation of cell death GO:0010942 184 0.012
fat cell proliferation GO:0070341 2 0.012
positive regulation of protein metabolic process GO:0051247 178 0.012
progesterone biosynthetic process GO:0006701 3 0.012
ribonucleotide metabolic process GO:0009259 231 0.012
muscle structure development GO:0061061 87 0.012
regulation of catalytic activity GO:0050790 304 0.012
Rat
regulation of response to wounding GO:1903034 69 0.012
anatomical structure formation involved in morphogenesis GO:0048646 83 0.012
oxidation reduction process GO:0055114 304 0.012
response to biotic stimulus GO:0009607 226 0.012
Rat
calcitriol biosynthetic process from calciol GO:0036378 2 0.012
cellular alcohol biosynthetic process GO:0044108 2 0.012
calcium ion import GO:0070509 22 0.012
regulation of mapk cascade GO:0043408 116 0.012
response to monosaccharide GO:0034284 159 0.012
cyclic purine nucleotide metabolic process GO:0052652 62 0.012
muscle cell migration GO:0014812 36 0.012
programmed cell death GO:0012501 392 0.012
Rat
ribose phosphate biosynthetic process GO:0046390 87 0.012
monovalent inorganic cation transport GO:0015672 172 0.012
enzyme linked receptor protein signaling pathway GO:0007167 116 0.012
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 55 0.012
response to electrical stimulus GO:0051602 56 0.012
fat soluble vitamin biosynthetic process GO:0042362 2 0.012
positive regulation of protein modification process GO:0031401 142 0.011
positive regulation of epithelial cell proliferation GO:0050679 32 0.011
regulation of cellular localization GO:0060341 263 0.011
sequestering of metal ion GO:0051238 9 0.011
rhythmic process GO:0048511 156 0.011
Rat
cellular response to biotic stimulus GO:0071216 59 0.011
response to gonadotropin GO:0034698 34 0.011
response to vitamin GO:0033273 131 0.011
negative regulation of multicellular organismal process GO:0051241 203 0.011
renal system process GO:0003014 40 0.011
neuron development GO:0048666 286 0.011
regulation of purine nucleotide metabolic process GO:1900542 115 0.011
sensory organ development GO:0007423 74 0.011
Rat
rna biosynthetic process GO:0032774 380 0.011
mononuclear cell proliferation GO:0032943 29 0.011
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
establishment of protein localization GO:0045184 141 0.011
neuron apoptotic process GO:0051402 88 0.011
epithelial cell differentiation GO:0030855 71 0.011
Rat
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
regulation of stem cell differentiation GO:2000736 2 0.011
positive regulation of homeostatic process GO:0032846 49 0.011
regulation of nucleotide metabolic process GO:0006140 117 0.011
negative regulation of secretion GO:0051048 82 0.011
urinary bladder smooth muscle contraction GO:0014832 4 0.011
glucocorticoid biosynthetic process GO:0006704 5 0.011
cellular response to peptide hormone stimulus GO:0071375 120 0.011
regulation of transcription dna templated GO:0006355 374 0.011
regulation of sodium ion transport GO:0002028 21 0.010
cellular response to metal ion GO:0071248 55 0.010
negative regulation of phosphate metabolic process GO:0045936 80 0.010
regulation of response to external stimulus GO:0032101 106 0.010
calcium ion transport into cytosol GO:0060402 38 0.010
secretion by tissue GO:0032941 37 0.010
anion transmembrane transport GO:0098656 77 0.010
carboxylic acid transport GO:0046942 115 0.010
regulation of neurological system process GO:0031644 43 0.010
positive regulation of immune system process GO:0002684 90 0.010
negative regulation of response to external stimulus GO:0032102 37 0.010
negative regulation of cell proliferation GO:0008285 119 0.010
Rat
response to estradiol GO:0032355 164 0.010
Rat
regulation of leukocyte activation GO:0002694 45 0.010
carbohydrate metabolic process GO:0005975 130 0.010

Cst12 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
congenital adrenal hyperplasia DOID:0050811 0 0.030
disease of metabolism DOID:0014667 0 0.030
lipid metabolism disorder DOID:3146 0 0.030
inherited metabolic disorder DOID:655 0 0.030
steroid inherited metabolic disorder DOID:1701 0 0.030
disease of anatomical entity DOID:7 0 0.013
urinary system disease DOID:18 0 0.013
endocrine system disease DOID:28 0 0.012
nervous system disease DOID:863 0 0.012