Rattus norvegicus

0 known processes

Hils1

histone linker H1 domain, spermatid-specific 1

Hils1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular component organization GO:0051128 368 0.095
cell projection organization GO:0030030 302 0.073
anatomical structure morphogenesis GO:0009653 298 0.069
regulation of molecular function GO:0065009 398 0.067
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.059
response to glucocorticoid GO:0051384 223 0.059
organic acid metabolic process GO:0006082 292 0.058
central nervous system development GO:0007417 311 0.055
oxoacid metabolic process GO:0043436 290 0.052
neuron projection development GO:0031175 273 0.049
protein phosphorylation GO:0006468 345 0.048
carboxylic acid metabolic process GO:0019752 289 0.048
response to corticosteroid GO:0031960 235 0.046
homeostatic process GO:0042592 331 0.046
negative regulation of gene expression GO:0010629 199 0.044
response to inorganic substance GO:0010035 377 0.043
regulation of rna metabolic process GO:0051252 391 0.042
cell morphogenesis GO:0000902 142 0.042
negative regulation of macromolecule metabolic process GO:0010605 260 0.042
neuron differentiation GO:0030182 368 0.039
transmembrane transport GO:0055085 412 0.038
negative regulation of metabolic process GO:0009892 331 0.038
response to ketone GO:1901654 182 0.037
rna biosynthetic process GO:0032774 380 0.037
negative regulation of cellular metabolic process GO:0031324 281 0.036
regulation of transcription dna templated GO:0006355 374 0.035
positive regulation of cellular component organization GO:0051130 200 0.035
regulation of cell differentiation GO:0045595 320 0.035
response to lipopolysaccharide GO:0032496 191 0.035
single organism cellular localization GO:1902580 102 0.034
positive regulation of biosynthetic process GO:0009891 319 0.034
cellular component assembly GO:0022607 360 0.033
chemical homeostasis GO:0048878 292 0.032
regulation of nucleic acid templated transcription GO:1903506 380 0.032
positive regulation of rna metabolic process GO:0051254 203 0.032
macromolecular complex assembly GO:0065003 273 0.031
protein autophosphorylation GO:0046777 66 0.031
head development GO:0060322 247 0.030
regulation of cell proliferation GO:0042127 359 0.030
neuron development GO:0048666 286 0.030
positive regulation of cell proliferation GO:0008284 249 0.030
transcription dna templated GO:0006351 377 0.030
multi organism reproductive process GO:0044703 262 0.029
positive regulation of developmental process GO:0051094 283 0.029
positive regulation of cell differentiation GO:0045597 217 0.029
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.029
inflammatory response GO:0006954 150 0.028
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.028
organelle organization GO:0006996 266 0.027
cellular component biogenesis GO:0044085 368 0.027
nucleic acid templated transcription GO:0097659 379 0.027
response to peptide hormone GO:0043434 278 0.027
regulation of phosphate metabolic process GO:0019220 349 0.027
regulation of protein phosphorylation GO:0001932 183 0.027
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.027
regulation of rna biosynthetic process GO:2001141 381 0.026
protein complex subunit organization GO:0071822 302 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.026
positive regulation of multicellular organismal process GO:0051240 387 0.025
organophosphate metabolic process GO:0019637 370 0.025
protein complex biogenesis GO:0070271 263 0.025
intracellular signal transduction GO:0035556 314 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
response to oxygen levels GO:0070482 265 0.024
positive regulation of cell development GO:0010720 176 0.024
response to decreased oxygen levels GO:0036293 237 0.024
positive regulation of molecular function GO:0044093 230 0.023
rna metabolic process GO:0016070 406 0.023
epithelium development GO:0060429 96 0.023
blood circulation GO:0008015 183 0.022
reproductive process GO:0022414 372 0.022
regulation of cellular amino acid metabolic process GO:0006521 2 0.022
cellular amino acid metabolic process GO:0006520 107 0.022
regulation of cell development GO:0060284 263 0.022
regeneration GO:0031099 163 0.022
regulation of cell projection organization GO:0031344 175 0.022
single organism carbohydrate metabolic process GO:0044723 118 0.021
brain development GO:0007420 247 0.021
response to molecule of bacterial origin GO:0002237 194 0.021
nitrogen compound transport GO:0071705 229 0.021
regulation of kinase activity GO:0043549 117 0.021
positive regulation of gene expression GO:0010628 244 0.021
aging GO:0007568 241 0.021
organ regeneration GO:0031100 101 0.021
ion homeostasis GO:0050801 212 0.021
anterior posterior pattern specification GO:0009952 1 0.020
organonitrogen compound biosynthetic process GO:1901566 167 0.020
single organism reproductive process GO:0044702 297 0.020
cell part morphogenesis GO:0032990 123 0.020
regulation of multicellular organismal development GO:2000026 376 0.020
regulation of protein modification process GO:0031399 194 0.020
response to wounding GO:0009611 254 0.020
regulation of system process GO:0044057 208 0.020
developmental process involved in reproduction GO:0003006 159 0.020
catabolic process GO:0009056 351 0.020
cellular amine metabolic process GO:0044106 38 0.020
regulation of protein metabolic process GO:0051246 289 0.020
liver development GO:0001889 90 0.020
hepaticobiliary system development GO:0061008 90 0.020
regulation of phosphorylation GO:0042325 248 0.020
apoptotic process GO:0006915 381 0.020
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.019
protein complex assembly GO:0006461 263 0.019
nucleobase containing small molecule metabolic process GO:0055086 316 0.019
single organism biosynthetic process GO:0044711 342 0.019
cellular component morphogenesis GO:0032989 155 0.019
cellular catabolic process GO:0044248 295 0.019
cation transport GO:0006812 382 0.019
negative regulation of cellular protein metabolic process GO:0032269 106 0.019
regulation of blood circulation GO:1903522 110 0.019
regulation of nervous system development GO:0051960 264 0.018
positive regulation of rna biosynthetic process GO:1902680 197 0.018
regulation of cellular localization GO:0060341 263 0.018
carbohydrate metabolic process GO:0005975 130 0.018
regulation of protein kinase activity GO:0045859 105 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.018
organic acid biosynthetic process GO:0016053 83 0.018
regulation of cellular ketone metabolic process GO:0010565 27 0.018
positive regulation of cellular amine metabolic process GO:0033240 3 0.018
macromolecular complex subunit organization GO:0043933 339 0.018
single organism catabolic process GO:0044712 283 0.018
negative regulation of nucleic acid templated transcription GO:1903507 117 0.018
negative regulation of rna biosynthetic process GO:1902679 118 0.018
positive regulation of cell communication GO:0010647 271 0.018
multicellular organism growth GO:0035264 1 0.017
response to oxidative stress GO:0006979 186 0.017
neuron projection morphogenesis GO:0048812 122 0.017
negative regulation of cellular biosynthetic process GO:0031327 161 0.017
metanephric s shaped body morphogenesis GO:0072284 2 0.017
protein oligomerization GO:0051259 191 0.017
regulation of neuron differentiation GO:0045664 208 0.017
cellular response to organic cyclic compound GO:0071407 202 0.017
regulation of transferase activity GO:0051338 123 0.017
negative regulation of transcription dna templated GO:0045892 116 0.017
amine metabolic process GO:0009308 38 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.017
cellular response to organonitrogen compound GO:0071417 197 0.017
macromolecule localization GO:0033036 252 0.017
carbohydrate derivative metabolic process GO:1901135 346 0.017
regulation of neuron projection development GO:0010975 161 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.016
response to hypoxia GO:0001666 231 0.016
ribose phosphate metabolic process GO:0019693 235 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
muscle system process GO:0003012 115 0.016
intracellular transport GO:0046907 185 0.016
regulation of cellular amine metabolic process GO:0033238 8 0.016
circulatory system process GO:0003013 183 0.016
oxidation reduction process GO:0055114 304 0.016
signal transduction by phosphorylation GO:0023014 144 0.016
negative regulation of multicellular organismal process GO:0051241 203 0.016
regulation of cellular protein metabolic process GO:0032268 267 0.016
cellular response to cytokine stimulus GO:0071345 127 0.016
regulation of catalytic activity GO:0050790 304 0.016
purine nucleotide metabolic process GO:0006163 229 0.016
positive regulation of cellular biosynthetic process GO:0031328 295 0.016
regulation of intracellular signal transduction GO:1902531 218 0.016
heterocycle catabolic process GO:0046700 167 0.016
regulation of cellular catabolic process GO:0031329 101 0.015
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.015
cation homeostasis GO:0055080 195 0.015
nucleoside metabolic process GO:0009116 179 0.015
aromatic compound catabolic process GO:0019439 168 0.015
small gtpase mediated signal transduction GO:0007264 36 0.015
reproductive structure development GO:0048608 128 0.015
ribonucleotide metabolic process GO:0009259 231 0.015
nucleoside phosphate metabolic process GO:0006753 283 0.015
cell projection morphogenesis GO:0048858 123 0.015
response to toxic substance GO:0009636 133 0.015
cell morphogenesis involved in neuron differentiation GO:0048667 106 0.015
positive regulation of programmed cell death GO:0043068 157 0.015
tissue development GO:0009888 252 0.015
ras protein signal transduction GO:0007265 29 0.015
cell migration GO:0016477 197 0.015
positive regulation of protein kinase activity GO:0045860 73 0.015
single organism organelle organization GO:1902589 180 0.015
sensory perception GO:0007600 101 0.014
response to acid chemical GO:0001101 222 0.014
positive regulation of phosphorus metabolic process GO:0010562 262 0.014
regulation of growth GO:0040008 105 0.014
cell adhesion GO:0007155 110 0.014
cellular ketone metabolic process GO:0042180 51 0.014
negative regulation of rna metabolic process GO:0051253 123 0.014
cellular nitrogen compound catabolic process GO:0044270 163 0.014
locomotion GO:0040011 237 0.014
programmed cell death GO:0012501 392 0.014
proteolysis GO:0006508 175 0.014
localization of cell GO:0051674 202 0.014
multicellular organism reproduction GO:0032504 233 0.014
response to carbohydrate GO:0009743 183 0.014
ion transmembrane transport GO:0034220 365 0.014
transcription from rna polymerase ii promoter GO:0006366 252 0.014
cardiac chamber development GO:0003205 1 0.014
response to estradiol GO:0032355 164 0.014
positive regulation of response to stimulus GO:0048584 285 0.014
purine containing compound catabolic process GO:0072523 138 0.014
purine nucleotide biosynthetic process GO:0006164 83 0.013
response to radiation GO:0009314 137 0.013
glycosyl compound metabolic process GO:1901657 182 0.013
purine nucleotide catabolic process GO:0006195 136 0.013
actin filament based process GO:0030029 86 0.013
gland development GO:0048732 155 0.013
cellular protein localization GO:0034613 122 0.013
negative regulation of signaling GO:0023057 157 0.013
carbohydrate derivative biosynthetic process GO:1901137 124 0.013
regulation of neurogenesis GO:0050767 247 0.013
synaptic transmission GO:0007268 235 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
response to metal ion GO:0010038 253 0.013
axon development GO:0061564 96 0.013
positive regulation of neurogenesis GO:0050769 165 0.013
purine ribonucleoside metabolic process GO:0046128 168 0.013
gliogenesis GO:0042063 93 0.013
cellular component movement GO:0006928 248 0.013
response to estrogen GO:0043627 232 0.013
secretion GO:0046903 307 0.013
response to reactive oxygen species GO:0000302 120 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
cellular calcium ion homeostasis GO:0006874 160 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
regulation of protein transport GO:0051223 68 0.013
muscle structure development GO:0061061 87 0.013
positive regulation of cell death GO:0010942 184 0.013
cellular response to stress GO:0033554 269 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
negative regulation of protein metabolic process GO:0051248 114 0.013
axonogenesis GO:0007409 71 0.013
regulation of catabolic process GO:0009894 113 0.013
organophosphate biosynthetic process GO:0090407 143 0.013
purine nucleoside monophosphate metabolic process GO:0009126 84 0.012
regulation of programmed cell death GO:0043067 341 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.012
reproduction GO:0000003 245 0.012
response to nutrient levels GO:0031667 370 0.012
nucleoside phosphate catabolic process GO:1901292 140 0.012
negative regulation of biosynthetic process GO:0009890 168 0.012
cellular response to acid chemical GO:0071229 75 0.012
cellular macromolecule localization GO:0070727 122 0.012
heart morphogenesis GO:0003007 3 0.012
ribonucleoside metabolic process GO:0009119 174 0.012
secretion by cell GO:0032940 248 0.012
nucleotide metabolic process GO:0009117 279 0.012
positive regulation of transferase activity GO:0051347 81 0.012
negative regulation of catalytic activity GO:0043086 103 0.012
regulation of protein serine threonine kinase activity GO:0071900 64 0.012
nucleoside catabolic process GO:0009164 126 0.012
multicellular organismal reproductive process GO:0048609 233 0.012
rho protein signal transduction GO:0007266 11 0.012
protein localization GO:0008104 191 0.012
growth GO:0040007 165 0.012
negative regulation of transport GO:0051051 136 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
negative regulation of molecular function GO:0044092 133 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.011
male gamete generation GO:0048232 99 0.011
response to transition metal nanoparticle GO:1990267 122 0.011
morphogenesis of embryonic epithelium GO:0016331 3 0.011
response to external biotic stimulus GO:0043207 221 0.011
inner ear morphogenesis GO:0042472 1 0.011
cell cycle GO:0007049 101 0.011
hematopoietic progenitor cell differentiation GO:0002244 2 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
cell morphogenesis involved in differentiation GO:0000904 119 0.011
response to hydrogen peroxide GO:0042542 89 0.011
positive regulation of protein modification process GO:0031401 142 0.011
regulation of cell growth GO:0001558 85 0.011
positive regulation of nucleic acid templated transcription GO:1903508 197 0.011
ribonucleoside monophosphate metabolic process GO:0009161 88 0.011
positive regulation of cellular protein metabolic process GO:0032270 167 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
organic cyclic compound catabolic process GO:1901361 175 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
regulation of membrane potential GO:0042391 110 0.011
positive regulation of catalytic activity GO:0043085 184 0.011
salivary gland development GO:0007431 3 0.011
spermatogenesis GO:0007283 99 0.011
positive regulation of transcription dna templated GO:0045893 197 0.011
purine containing compound metabolic process GO:0072521 253 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
positive regulation of signaling GO:0023056 270 0.011
gamete generation GO:0007276 124 0.011
intestinal absorption GO:0050892 3 0.011
maintenance of location GO:0051235 17 0.011
actin cytoskeleton organization GO:0030036 73 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
purine ribonucleotide catabolic process GO:0009154 136 0.011
regulation of anatomical structure morphogenesis GO:0022603 141 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
regulation of hormone levels GO:0010817 187 0.011
regulation of apoptotic process GO:0042981 335 0.011
cellular chemical homeostasis GO:0055082 247 0.010
cell type specific apoptotic process GO:0097285 134 0.010
lipid transport GO:0006869 61 0.010
olfactory behavior GO:0042048 2 0.010
nucleoside monophosphate metabolic process GO:0009123 93 0.010
regulation of metanephros development GO:0072215 4 0.010
organophosphate catabolic process GO:0046434 148 0.010
nucleotide catabolic process GO:0009166 139 0.010
peptide transport GO:0015833 97 0.010
chromosome segregation GO:0007059 2 0.010
cytoskeleton organization GO:0007010 111 0.010
stem cell division GO:0017145 4 0.010
cellular homeostasis GO:0019725 252 0.010
response to testosterone GO:0033574 55 0.010
regulation of cellular component biogenesis GO:0044087 86 0.010
protein transport GO:0015031 132 0.010
regulation of purine nucleotide metabolic process GO:1900542 115 0.010
circadian rhythm GO:0007623 88 0.010
neuron death GO:0070997 127 0.010
establishment of protein localization GO:0045184 141 0.010
neuron fate commitment GO:0048663 4 0.010

Hils1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
musculoskeletal system disease DOID:17 0 0.020
bone disease DOID:0080001 0 0.013
connective tissue disease DOID:65 0 0.013
nervous system disease DOID:863 0 0.012