Rattus norvegicus

0 known processes

Plac8

placenta-specific 8

Plac8 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
response to biotic stimulus GO:0009607 226 0.241
biological adhesion GO:0022610 110 0.218
immunoglobulin mediated immune response GO:0016064 4 0.202
cellular component assembly GO:0022607 360 0.170
response to other organism GO:0051707 220 0.153
organic substance catabolic process GO:1901575 316 0.141
positive regulation of cell proliferation GO:0008284 249 0.131
macromolecular complex subunit organization GO:0043933 339 0.128
tissue development GO:0009888 252 0.126
carboxylic acid metabolic process GO:0019752 289 0.120
anatomical structure morphogenesis GO:0009653 298 0.120
regulation of cellular protein metabolic process GO:0032268 267 0.115
regulation of protein metabolic process GO:0051246 289 0.113
cell motility GO:0048870 202 0.099
regulation of catalytic activity GO:0050790 304 0.098
anterior posterior pattern specification GO:0009952 1 0.094
macromolecular complex assembly GO:0065003 273 0.094
signal transduction by phosphorylation GO:0023014 144 0.089
positive regulation of cellular protein metabolic process GO:0032270 167 0.088
organic acid metabolic process GO:0006082 292 0.088
catabolic process GO:0009056 351 0.084
glomerular mesangial cell proliferation GO:0072110 4 0.083
positive regulation of developmental process GO:0051094 283 0.080
regulation of mapk cascade GO:0043408 116 0.078
response to bacterium GO:0009617 200 0.078
response to nutrient GO:0007584 248 0.077
platelet derived growth factor production GO:0090360 2 0.076
regulation of programmed cell death GO:0043067 341 0.074
regulation of phosphorylation GO:0042325 248 0.071
regulation of multicellular organismal development GO:2000026 376 0.069
protein complex biogenesis GO:0070271 263 0.069
immune system process GO:0002376 204 0.068
negative regulation of macromolecule metabolic process GO:0010605 260 0.068
mapk cascade GO:0000165 140 0.065
nucleobase containing small molecule metabolic process GO:0055086 316 0.062
response to external biotic stimulus GO:0043207 221 0.061
cellular ketone metabolic process GO:0042180 51 0.060
cellular component movement GO:0006928 248 0.059
intracellular signal transduction GO:0035556 314 0.059
regulation of molecular function GO:0065009 398 0.058
cellular component biogenesis GO:0044085 368 0.058
b cell mediated immunity GO:0019724 4 0.058
protein complex assembly GO:0006461 263 0.057
regulation of phosphate metabolic process GO:0019220 349 0.055
apoptotic process GO:0006915 381 0.054
regulation of phosphorus metabolic process GO:0051174 349 0.054
amine metabolic process GO:0009308 38 0.053
positive regulation of immunoglobulin production GO:0002639 4 0.053
negative regulation of metabolic process GO:0009892 331 0.052
regulation of cell differentiation GO:0045595 320 0.052
cellular catabolic process GO:0044248 295 0.051
response to zinc ion GO:0010043 39 0.051
organic acid biosynthetic process GO:0016053 83 0.051
positive regulation of molecular function GO:0044093 230 0.051
organic cyclic compound catabolic process GO:1901361 175 0.051
cellular response to endogenous stimulus GO:0071495 377 0.050
positive regulation of catalytic activity GO:0043085 184 0.050
regulation of cellular amine metabolic process GO:0033238 8 0.049
programmed cell death GO:0012501 392 0.049
response to inorganic substance GO:0010035 377 0.049
regulation of b cell differentiation GO:0045577 1 0.048
oxoacid metabolic process GO:0043436 290 0.048
regulation of anatomical structure morphogenesis GO:0022603 141 0.048
regulation of cellular ketone metabolic process GO:0010565 27 0.046
carboxylic acid biosynthetic process GO:0046394 83 0.046
proteolysis GO:0006508 175 0.046
fatty acid derivative metabolic process GO:1901568 38 0.046
positive regulation of cell death GO:0010942 184 0.045
protein phosphorylation GO:0006468 345 0.045
cellular component morphogenesis GO:0032989 155 0.044
cellular amino acid metabolic process GO:0006520 107 0.043
chemotaxis GO:0006935 66 0.043
protein oligomerization GO:0051259 191 0.043
regulation of cell proliferation GO:0042127 359 0.042
cell projection organization GO:0030030 302 0.042
protein transport GO:0015031 132 0.042
protein localization GO:0008104 191 0.041
positive regulation of phosphate metabolic process GO:0045937 262 0.041
protein complex subunit organization GO:0071822 302 0.040
positive regulation of phosphorus metabolic process GO:0010562 262 0.040
monocarboxylic acid metabolic process GO:0032787 152 0.039
glomerulus development GO:0032835 10 0.039
cytokine mediated signaling pathway GO:0019221 43 0.038
regulation of cell motility GO:2000145 131 0.038
positive regulation of programmed cell death GO:0043068 157 0.038
response to wounding GO:0009611 254 0.038
single organism biosynthetic process GO:0044711 342 0.038
establishment of protein localization GO:0045184 141 0.038
aromatic compound catabolic process GO:0019439 168 0.037
regulation of locomotion GO:0040012 148 0.037
cell activation GO:0001775 97 0.037
response to growth factor GO:0070848 189 0.036
cellular protein localization GO:0034613 122 0.036
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.036
cell cell signaling GO:0007267 335 0.036
neuron differentiation GO:0030182 368 0.036
cytoskeleton organization GO:0007010 111 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.035
positive regulation of multicellular organismal process GO:0051240 387 0.034
positive regulation of apoptotic process GO:0043065 154 0.034
ribonucleoside triphosphate metabolic process GO:0009199 141 0.034
fatty acid biosynthetic process GO:0006633 33 0.034
positive regulation of cellular component organization GO:0051130 200 0.034
cell migration GO:0016477 197 0.033
regulation of protein phosphorylation GO:0001932 183 0.033
negative regulation of cellular metabolic process GO:0031324 281 0.033
cardiovascular system development GO:0072358 134 0.033
regulation of cellular amino acid metabolic process GO:0006521 2 0.033
nucleotide metabolic process GO:0009117 279 0.032
macromolecule localization GO:0033036 252 0.032
organophosphate metabolic process GO:0019637 370 0.032
purine containing compound metabolic process GO:0072521 253 0.032
immune response GO:0006955 104 0.031
regulation of cellular component organization GO:0051128 368 0.031
regulation of cell development GO:0060284 263 0.031
regulation of apoptotic process GO:0042981 335 0.031
intracellular transport GO:0046907 185 0.031
multicellular organismal reproductive process GO:0048609 233 0.030
antigen processing and presentation of peptide antigen via mhc class ii GO:0002495 1 0.030
small molecule biosynthetic process GO:0044283 124 0.030
locomotion GO:0040011 237 0.030
positive regulation of chemokine production GO:0032722 4 0.030
regulation of rna biosynthetic process GO:2001141 381 0.030
positive regulation of biosynthetic process GO:0009891 319 0.030
regulation of response to stress GO:0080134 126 0.029
nucleoside phosphate metabolic process GO:0006753 283 0.029
positive regulation of cell differentiation GO:0045597 217 0.029
single organism intracellular transport GO:1902582 166 0.029
regulation of protein modification process GO:0031399 194 0.029
icosanoid metabolic process GO:0006690 38 0.029
cellular response to growth factor stimulus GO:0071363 162 0.028
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.028
b cell differentiation GO:0030183 2 0.028
regulation of jnk cascade GO:0046328 19 0.028
regulation of stress activated protein kinase signaling cascade GO:0070302 23 0.028
leukocyte activation GO:0045321 76 0.028
positive regulation of protein metabolic process GO:0051247 178 0.028
cellular response to hormone stimulus GO:0032870 247 0.027
circulatory system development GO:0072359 134 0.027
defense response GO:0006952 194 0.027
epithelium development GO:0060429 96 0.027
cellular amine metabolic process GO:0044106 38 0.027
positive regulation of cellular component movement GO:0051272 102 0.026
positive regulation of glomerulus development GO:0090193 4 0.026
cellular metal ion homeostasis GO:0006875 172 0.026
regulation of immunoglobulin production GO:0002637 4 0.026
regulation of kinase activity GO:0043549 117 0.026
t cell activation GO:0042110 29 0.026
negative regulation of protein metabolic process GO:0051248 114 0.026
positive regulation of response to stimulus GO:0048584 285 0.025
reproductive process GO:0022414 372 0.025
response to carbohydrate GO:0009743 183 0.025
single organism catabolic process GO:0044712 283 0.025
unsaturated fatty acid biosynthetic process GO:0006636 21 0.025
single organism cellular localization GO:1902580 102 0.025
glycosyl compound catabolic process GO:1901658 126 0.024
negative regulation of cellular biosynthetic process GO:0031327 161 0.024
lipid metabolic process GO:0006629 283 0.024
anatomical structure formation involved in morphogenesis GO:0048646 83 0.024
response to peptide hormone GO:0043434 278 0.024
regulation of cell adhesion GO:0030155 52 0.024
regulation of protein kinase activity GO:0045859 105 0.024
rna biosynthetic process GO:0032774 380 0.024
cellular nitrogen compound catabolic process GO:0044270 163 0.024
cell morphogenesis GO:0000902 142 0.024
monocarboxylic acid biosynthetic process GO:0072330 48 0.023
response to molecule of bacterial origin GO:0002237 194 0.023
antigen processing and presentation of peptide antigen GO:0048002 2 0.023
positive regulation of cellular amine metabolic process GO:0033240 3 0.023
rna metabolic process GO:0016070 406 0.023
purine nucleoside metabolic process GO:0042278 169 0.022
purine nucleotide metabolic process GO:0006163 229 0.022
negative regulation of programmed cell death GO:0043069 183 0.022
purine ribonucleoside metabolic process GO:0046128 168 0.022
positive regulation of nervous system development GO:0051962 178 0.022
neuron projection development GO:0031175 273 0.022
regulation of arp2 3 complex mediated actin nucleation GO:0034315 2 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.022
cellular macromolecule localization GO:0070727 122 0.022
kidney vasculature development GO:0061440 6 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.021
regulation of cellular localization GO:0060341 263 0.021
regulation of cell activation GO:0050865 50 0.021
organonitrogen compound catabolic process GO:1901565 179 0.021
carbohydrate derivative metabolic process GO:1901135 346 0.021
cell adhesion GO:0007155 110 0.021
heterocycle catabolic process GO:0046700 167 0.021
positive regulation of mapk cascade GO:0043410 92 0.021
regulation of t cell differentiation GO:0045580 7 0.021
negative regulation of biosynthetic process GO:0009890 168 0.020
wound healing GO:0042060 122 0.020
developmental process involved in reproduction GO:0003006 159 0.020
regulation of cytokine production GO:0001817 56 0.020
positive regulation of cell projection organization GO:0031346 111 0.020
peptidyl tyrosine phosphorylation GO:0018108 72 0.020
regulation of lymphocyte proliferation GO:0050670 26 0.020
axis specification GO:0009798 4 0.020
axon development GO:0061564 96 0.019
regulation of intracellular signal transduction GO:1902531 218 0.019
peptide secretion GO:0002790 86 0.019
cellular lipid metabolic process GO:0044255 208 0.019
single organism reproductive process GO:0044702 297 0.019
positive regulation of transforming growth factor beta1 production GO:0032914 2 0.019
membrane organization GO:0061024 94 0.019
positive regulation of cytokine production GO:0001819 42 0.019
organophosphate catabolic process GO:0046434 148 0.019
urogenital system development GO:0001655 78 0.019
intracellular protein transport GO:0006886 79 0.019
regulation of cellular component movement GO:0051270 150 0.019
positive regulation of protein phosphorylation GO:0001934 135 0.019
single organism organelle organization GO:1902589 180 0.019
regulation of transcription dna templated GO:0006355 374 0.019
positive regulation of intracellular signal transduction GO:1902533 138 0.019
positive regulation of signal transduction GO:0009967 175 0.018
regulation of catabolic process GO:0009894 113 0.018
protein maturation GO:0051604 68 0.018
negative regulation of viral process GO:0048525 4 0.018
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.018
hemopoiesis GO:0030097 34 0.018
embryonic pattern specification GO:0009880 1 0.018
response to peptide GO:1901652 292 0.018
nucleic acid templated transcription GO:0097659 379 0.018
transforming growth factor beta1 production GO:0032905 2 0.018
de novo posttranslational protein folding GO:0051084 2 0.018
glomerular mesangium development GO:0072109 4 0.018
positive regulation of protein kinase activity GO:0045860 73 0.017
purine nucleotide catabolic process GO:0006195 136 0.017
regulation of response to wounding GO:1903034 69 0.017
regulation of transferase activity GO:0051338 123 0.017
nucleotide catabolic process GO:0009166 139 0.017
response to ketone GO:1901654 182 0.017
regulation of hydrolase activity GO:0051336 143 0.017
jnk cascade GO:0007254 28 0.017
actin filament based process GO:0030029 86 0.017
regulation of hormone levels GO:0010817 187 0.017
signal release GO:0023061 145 0.017
glycosyl compound metabolic process GO:1901657 182 0.017
positive regulation of hydrolase activity GO:0051345 86 0.017
nucleoside phosphate catabolic process GO:1901292 140 0.017
positive regulation of protein serine threonine kinase activity GO:0071902 52 0.017
regulation of anatomical structure size GO:0090066 135 0.016
cellular homeostasis GO:0019725 252 0.016
cell type specific apoptotic process GO:0097285 134 0.016
response to cytokine GO:0034097 215 0.016
positive regulation of cell development GO:0010720 176 0.016
purine nucleoside catabolic process GO:0006152 124 0.016
renal system development GO:0072001 67 0.016
secretion GO:0046903 307 0.016
cell part morphogenesis GO:0032990 123 0.016
positive regulation of cellular biosynthetic process GO:0031328 295 0.016
negative regulation of molecular function GO:0044092 133 0.016
regulation of stress activated mapk cascade GO:0032872 23 0.016
regulation of cellular response to stress GO:0080135 49 0.016
response to transition metal nanoparticle GO:1990267 122 0.016
response to nutrient levels GO:0031667 370 0.016
cellular response to stress GO:0033554 269 0.016
platelet aggregation GO:0070527 4 0.016
regulation of nervous system development GO:0051960 264 0.016
nucleoside metabolic process GO:0009116 179 0.016
nucleoside catabolic process GO:0009164 126 0.016
nucleobase containing compound catabolic process GO:0034655 152 0.016
purine ribonucleotide metabolic process GO:0009150 227 0.015
negative regulation of cell death GO:0060548 229 0.015
positive regulation of phosphorylation GO:0042327 177 0.015
ribonucleoside triphosphate catabolic process GO:0009203 122 0.015
regulation of cell migration GO:0030334 128 0.015
regulation of body fluid levels GO:0050878 90 0.015
positive regulation of leukocyte proliferation GO:0070665 20 0.015
negative regulation of signaling GO:0023057 157 0.015
ribose phosphate metabolic process GO:0019693 235 0.015
negative regulation of arp2 3 complex mediated actin nucleation GO:0034316 1 0.015
arp2 3 complex mediated actin nucleation GO:0034314 2 0.015
localization of cell GO:0051674 202 0.015
lipid biosynthetic process GO:0008610 128 0.015
dephosphorylation GO:0016311 98 0.014
negative regulation of signal transduction GO:0009968 83 0.014
response to extracellular stimulus GO:0009991 380 0.014
sexual reproduction GO:0019953 148 0.014
actin filament branching GO:0090135 1 0.014
purine containing compound catabolic process GO:0072523 138 0.014
positive regulation of cell communication GO:0010647 271 0.014
nucleoside triphosphate catabolic process GO:0009143 123 0.014
blood vessel development GO:0001568 69 0.014
mononuclear cell proliferation GO:0032943 29 0.014
leukocyte cell cell adhesion GO:0007159 4 0.014
response to metal ion GO:0010038 253 0.014
response to acid chemical GO:0001101 222 0.014
positive regulation of glomerular mesangial cell proliferation GO:0072126 4 0.014
lymphocyte proliferation GO:0046651 29 0.014
transcription dna templated GO:0006351 377 0.014
positive regulation of signaling GO:0023056 270 0.014
single organismal cell cell adhesion GO:0016337 42 0.014
response to monosaccharide GO:0034284 159 0.014
positive regulation of jnk cascade GO:0046330 13 0.014
single organism cell adhesion GO:0098602 46 0.014
regulation of secretion GO:0051046 224 0.014
taxis GO:0042330 67 0.014
regulation of neuron projection development GO:0010975 161 0.014
cellular response to oxygen containing compound GO:1901701 386 0.014
regulation of erk1 and erk2 cascade GO:0070372 41 0.014
reproductive system development GO:0061458 128 0.014
response to decreased oxygen levels GO:0036293 237 0.014
positive regulation of isotype switching GO:0045830 1 0.013
multicellular organism reproduction GO:0032504 233 0.013
antigen processing and presentation GO:0019882 2 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.013
alcohol metabolic process GO:0006066 77 0.013
regulation of leukocyte activation GO:0002694 45 0.013
regulation of neurogenesis GO:0050767 247 0.013
purine nucleoside triphosphate metabolic process GO:0009144 141 0.013
t cell selection GO:0045058 1 0.013
metal ion transport GO:0030001 289 0.013
macromolecule catabolic process GO:0009057 58 0.013
regulation of actin filament based process GO:0032970 42 0.013
negative regulation of developmental process GO:0051093 125 0.013
regulation of cellular extravasation GO:0002691 2 0.013
head development GO:0060322 247 0.013
ribonucleoside catabolic process GO:0042454 126 0.013
positive regulation of immunoglobulin mediated immune response GO:0002891 2 0.013
unsaturated fatty acid metabolic process GO:0033559 39 0.013
regulation of proteolysis GO:0030162 66 0.013
positive regulation of transferase activity GO:0051347 81 0.013
regulation of cell projection organization GO:0031344 175 0.013
gamete generation GO:0007276 124 0.013
response to estrogen GO:0043627 232 0.013
regulation of glomerulus development GO:0090192 4 0.013
small gtpase mediated signal transduction GO:0007264 36 0.013
response to hexose GO:0009746 144 0.013
response to axon injury GO:0048678 59 0.013
muscle structure development GO:0061061 87 0.013
protein heterooligomerization GO:0051291 89 0.013
cellular response to peptide hormone stimulus GO:0071375 120 0.013
positive regulation of t cell differentiation GO:0045582 6 0.013
single organism membrane organization GO:0044802 74 0.012
gland development GO:0048732 155 0.012
negative regulation of phosphorus metabolic process GO:0010563 80 0.012
regulation of neuron death GO:1901214 115 0.012
positive regulation of cell activation GO:0050867 34 0.012
regulation of signal transduction GO:0009966 318 0.012
ribonucleotide catabolic process GO:0009261 136 0.012
embryonic axis specification GO:0000578 1 0.012
cell cycle GO:0007049 101 0.012
innate immune response GO:0045087 35 0.012
positive regulation of platelet derived growth factor production GO:0090362 2 0.012
regulation of neuron differentiation GO:0045664 208 0.012
hematopoietic progenitor cell differentiation GO:0002244 2 0.012
negative regulation of homeostatic process GO:0032845 47 0.012
positive regulation of protein modification process GO:0031401 142 0.012
lipid storage GO:0019915 1 0.012
regulation of leukocyte proliferation GO:0070663 26 0.012
mitotic spindle organization GO:0007052 2 0.012
organelle organization GO:0006996 266 0.012
lymphocyte activation GO:0046649 43 0.011
behavior GO:0007610 205 0.011
brain development GO:0007420 247 0.011
regulation of cytokine biosynthetic process GO:0042035 3 0.011
negative regulation of cell communication GO:0010648 158 0.011
leukocyte proliferation GO:0070661 29 0.011
negative regulation of catalytic activity GO:0043086 103 0.011
establishment of organelle localization GO:0051656 37 0.011
spindle organization GO:0007051 2 0.011
rho protein signal transduction GO:0007266 11 0.011
regulation of cell morphogenesis GO:0022604 77 0.011
regulation of cellular component biogenesis GO:0044087 86 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
chemical homeostasis GO:0048878 292 0.011
regulation of glomerular mesangial cell proliferation GO:0072124 4 0.011
negative regulation of nervous system development GO:0051961 79 0.011
hormone secretion GO:0046879 115 0.011
positive regulation of immune system process GO:0002684 90 0.011
response to molecule of fungal origin GO:0002238 3 0.011
regulation of t cell activation GO:0050863 23 0.011
salivary gland development GO:0007431 3 0.011
positive regulation of lymphocyte proliferation GO:0050671 20 0.011
cell projection morphogenesis GO:0048858 123 0.011
positive regulation of neutrophil chemotaxis GO:0090023 5 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.011
vasculature development GO:0001944 70 0.011
negative regulation of apoptotic process GO:0043066 181 0.011
regulation of membrane potential GO:0042391 110 0.011
cell junction maintenance GO:0034331 1 0.011
cellular component maintenance GO:0043954 4 0.010
amide transport GO:0042886 105 0.010
protein targeting GO:0006605 61 0.010
circulatory system process GO:0003013 183 0.010
negative regulation of actin nucleation GO:0051126 1 0.010
regulation of establishment of protein localization GO:0070201 69 0.010
regulation of rna metabolic process GO:0051252 391 0.010
cognition GO:0050890 92 0.010
somatic diversification of immune receptors via germline recombination within a single locus GO:0002562 2 0.010
glomerulus vasculature development GO:0072012 6 0.010
positive regulation of neuron differentiation GO:0045666 126 0.010
central nervous system development GO:0007417 311 0.010
reproduction GO:0000003 245 0.010

Plac8 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org