Rattus norvegicus

0 known processes

Npl

N-acetylneuraminate pyruvate lyase

Npl biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic substance catabolic process GO:1901575 316 0.059
organic acid metabolic process GO:0006082 292 0.040
brain development GO:0007420 247 0.040
catabolic process GO:0009056 351 0.039
rna metabolic process GO:0016070 406 0.039
carboxylic acid metabolic process GO:0019752 289 0.037
response to extracellular stimulus GO:0009991 380 0.033
aging GO:0007568 241 0.033
amine metabolic process GO:0009308 38 0.032
central nervous system development GO:0007417 311 0.030
response to metal ion GO:0010038 253 0.030
transmembrane transport GO:0055085 412 0.030
ion transmembrane transport GO:0034220 365 0.029
oxoacid metabolic process GO:0043436 290 0.028
response to inorganic substance GO:0010035 377 0.026
regulation of molecular function GO:0065009 398 0.026
head development GO:0060322 247 0.025
organonitrogen compound catabolic process GO:1901565 179 0.024
neuron projection development GO:0031175 273 0.024
cellular amino acid metabolic process GO:0006520 107 0.023
carbohydrate derivative metabolic process GO:1901135 346 0.023
neuron development GO:0048666 286 0.023
cellular amine metabolic process GO:0044106 38 0.023
single organism biosynthetic process GO:0044711 342 0.023
reproductive process GO:0022414 372 0.022
cellular catabolic process GO:0044248 295 0.022
anion transport GO:0006820 178 0.022
negative regulation of cell communication GO:0010648 158 0.022
organonitrogen compound biosynthetic process GO:1901566 167 0.021
metal ion homeostasis GO:0055065 186 0.021
regulation of cellular amine metabolic process GO:0033238 8 0.021
single organism catabolic process GO:0044712 283 0.021
cellular response to oxygen containing compound GO:1901701 386 0.021
anatomical structure morphogenesis GO:0009653 298 0.021
inorganic ion transmembrane transport GO:0098660 229 0.021
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.020
cation homeostasis GO:0055080 195 0.020
respiratory system development GO:0060541 45 0.020
nucleobase containing small molecule metabolic process GO:0055086 316 0.020
neuron differentiation GO:0030182 368 0.020
cellular metal ion homeostasis GO:0006875 172 0.020
cation transmembrane transport GO:0098655 263 0.019
cation transport GO:0006812 382 0.019
regulation of catalytic activity GO:0050790 304 0.019
reproduction GO:0000003 245 0.019
intracellular signal transduction GO:0035556 314 0.019
response to nutrient levels GO:0031667 370 0.018
regulation of signal transduction GO:0009966 318 0.018
positive regulation of molecular function GO:0044093 230 0.018
chemical homeostasis GO:0048878 292 0.018
metal ion transport GO:0030001 289 0.018
organic anion transport GO:0015711 132 0.018
single organism reproductive process GO:0044702 297 0.018
response to lipopolysaccharide GO:0032496 191 0.018
inflammatory response GO:0006954 150 0.018
cellular ketone metabolic process GO:0042180 51 0.017
protein complex assembly GO:0006461 263 0.017
cellular response to nitrogen compound GO:1901699 210 0.017
cellular divalent inorganic cation homeostasis GO:0072503 162 0.017
homeostatic process GO:0042592 331 0.017
nucleotide metabolic process GO:0009117 279 0.017
cellular amide metabolic process GO:0043603 44 0.017
nucleoside phosphate metabolic process GO:0006753 283 0.017
secretion GO:0046903 307 0.017
positive regulation of cellular amine metabolic process GO:0033240 3 0.017
response to nutrient GO:0007584 248 0.017
negative regulation of metabolic process GO:0009892 331 0.017
response to biotic stimulus GO:0009607 226 0.016
ion homeostasis GO:0050801 212 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
inorganic cation transmembrane transport GO:0098662 202 0.016
sulfur compound metabolic process GO:0006790 70 0.016
cellular response to stress GO:0033554 269 0.016
proteolysis GO:0006508 175 0.016
regulation of cellular amino acid metabolic process GO:0006521 2 0.016
response to estrogen GO:0043627 232 0.016
organophosphate metabolic process GO:0019637 370 0.016
nitrogen compound transport GO:0071705 229 0.016
organelle organization GO:0006996 266 0.016
tissue development GO:0009888 252 0.016
multicellular organism reproduction GO:0032504 233 0.015
response to external biotic stimulus GO:0043207 221 0.015
regulation of homeostatic process GO:0032844 101 0.015
response to ketone GO:1901654 182 0.015
rna biosynthetic process GO:0032774 380 0.015
regulation of cellular ketone metabolic process GO:0010565 27 0.015
regulation of transcription dna templated GO:0006355 374 0.015
organic acid transport GO:0015849 116 0.015
purine nucleotide metabolic process GO:0006163 229 0.015
programmed cell death GO:0012501 392 0.015
monovalent inorganic cation transport GO:0015672 172 0.015
multi organism reproductive process GO:0044703 262 0.015
regulation of cell differentiation GO:0045595 320 0.015
protein oligomerization GO:0051259 191 0.015
purine ribonucleotide metabolic process GO:0009150 227 0.015
regulation of cell development GO:0060284 263 0.015
response to peptide hormone GO:0043434 278 0.015
cellular cation homeostasis GO:0030003 180 0.014
positive regulation of cell differentiation GO:0045597 217 0.014
regulation of secretion by cell GO:1903530 208 0.014
regulation of nucleic acid templated transcription GO:1903506 380 0.014
regulation of apoptotic process GO:0042981 335 0.014
response to wounding GO:0009611 254 0.014
calcium ion homeostasis GO:0055074 162 0.014
rhythmic process GO:0048511 156 0.014
small gtpase mediated signal transduction GO:0007264 36 0.014
locomotion GO:0040011 237 0.014
regulation of ion transport GO:0043269 245 0.014
cellular ion homeostasis GO:0006873 184 0.014
positive regulation of cell death GO:0010942 184 0.014
purine containing compound metabolic process GO:0072521 253 0.014
apoptotic process GO:0006915 381 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
positive regulation of developmental process GO:0051094 283 0.014
nucleic acid templated transcription GO:0097659 379 0.014
g protein coupled receptor signaling pathway GO:0007186 242 0.014
cellular calcium ion homeostasis GO:0006874 160 0.014
response to peptide GO:1901652 292 0.014
macromolecular complex assembly GO:0065003 273 0.014
regulation of hydrolase activity GO:0051336 143 0.014
ribonucleoside catabolic process GO:0042454 126 0.014
response to transition metal nanoparticle GO:1990267 122 0.013
response to molecule of bacterial origin GO:0002237 194 0.013
response to alkaloid GO:0043279 132 0.013
cellular homeostasis GO:0019725 252 0.013
response to decreased oxygen levels GO:0036293 237 0.013
multicellular organismal reproductive process GO:0048609 233 0.013
negative regulation of canonical wnt signaling pathway GO:0090090 4 0.013
regulation of cellular component organization GO:0051128 368 0.013
regulation of cellular protein metabolic process GO:0032268 267 0.013
regulation of programmed cell death GO:0043067 341 0.013
heterocycle catabolic process GO:0046700 167 0.013
regulation of rna biosynthetic process GO:2001141 381 0.013
positive regulation of response to stimulus GO:0048584 285 0.013
nucleoside metabolic process GO:0009116 179 0.013
transcription dna templated GO:0006351 377 0.013
synaptic transmission GO:0007268 235 0.013
cell projection organization GO:0030030 302 0.013
macromolecular complex subunit organization GO:0043933 339 0.013
cellular component biogenesis GO:0044085 368 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
ribose phosphate metabolic process GO:0019693 235 0.013
protein phosphorylation GO:0006468 345 0.012
wound healing GO:0042060 122 0.012
cellular chemical homeostasis GO:0055082 247 0.012
defense response GO:0006952 194 0.012
regulation of secretion GO:0051046 224 0.012
response to vitamin GO:0033273 131 0.012
muscle structure development GO:0061061 87 0.012
positive regulation of biosynthetic process GO:0009891 319 0.012
localization of cell GO:0051674 202 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
embryonic appendage morphogenesis GO:0035113 4 0.012
response to acid chemical GO:0001101 222 0.012
behavior GO:0007610 205 0.012
ossification GO:0001503 70 0.012
eye morphogenesis GO:0048592 4 0.012
limb morphogenesis GO:0035108 4 0.012
aromatic compound catabolic process GO:0019439 168 0.012
regulation of rna metabolic process GO:0051252 391 0.012
ras protein signal transduction GO:0007265 29 0.011
negative regulation of signaling GO:0023057 157 0.011
macromolecule localization GO:0033036 252 0.011
calcium ion transmembrane transport GO:0070588 70 0.011
neurological system process GO:0050877 219 0.011
sensory perception of pain GO:0019233 73 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
lung development GO:0030324 43 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
axis specification GO:0009798 4 0.011
ribonucleotide metabolic process GO:0009259 231 0.011
protein complex subunit organization GO:0071822 302 0.011
negative regulation of molecular function GO:0044092 133 0.011
regulation of phosphate metabolic process GO:0019220 349 0.011
positive regulation of multicellular organismal process GO:0051240 387 0.011
gastrulation GO:0007369 2 0.011
regeneration GO:0031099 163 0.011
cell motility GO:0048870 202 0.011
tube development GO:0035295 89 0.011
regulation of canonical wnt signaling pathway GO:0060828 4 0.011
cellular response to organonitrogen compound GO:0071417 197 0.011
growth GO:0040007 165 0.011
cellular component movement GO:0006928 248 0.011
circulatory system process GO:0003013 183 0.011
protein complex biogenesis GO:0070271 263 0.011
purine nucleoside metabolic process GO:0042278 169 0.011
maintenance of location GO:0051235 17 0.011
response to estradiol GO:0032355 164 0.011
appendage morphogenesis GO:0035107 4 0.011
glycosyl compound metabolic process GO:1901657 182 0.011
response to corticosteroid GO:0031960 235 0.011
secretion by cell GO:0032940 248 0.011
cell growth GO:0016049 104 0.010
regulation of phosphorylation GO:0042325 248 0.010
positive regulation of phosphorylation GO:0042327 177 0.010
regulation of system process GO:0044057 208 0.010
intracellular transport GO:0046907 185 0.010
axon development GO:0061564 96 0.010
negative regulation of transport GO:0051051 136 0.010
positive regulation of cellular biosynthetic process GO:0031328 295 0.010
negative regulation of cellular metabolic process GO:0031324 281 0.010
regulation of anatomical structure size GO:0090066 135 0.010
vesicle mediated transport GO:0016192 181 0.010
regulation of neuron differentiation GO:0045664 208 0.010
nucleobase containing compound catabolic process GO:0034655 152 0.010
embryonic limb morphogenesis GO:0030326 4 0.010
dicarboxylic acid metabolic process GO:0043648 42 0.010
negative regulation of gene expression GO:0010629 199 0.010
macromolecule catabolic process GO:0009057 58 0.010
positive regulation of signaling GO:0023056 270 0.010
positive regulation of transport GO:0051050 245 0.010

Npl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.022
nervous system disease DOID:863 0 0.022
disease of metabolism DOID:0014667 0 0.014
central nervous system disease DOID:331 0 0.012
inherited metabolic disorder DOID:655 0 0.010