Rattus norvegicus

14 known processes

Eif4e

eukaryotic translation initiation factor 4E

(Aliases: MGC93265)

Eif4e biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to peptide GO:1901652 292 0.156
catabolic process GO:0009056 351 0.142
organic substance catabolic process GO:1901575 316 0.135
cellular catabolic process GO:0044248 295 0.125
response to insulin GO:0032868 133 0.123
cellular response to nitrogen compound GO:1901699 210 0.111
cellular response to endogenous stimulus GO:0071495 377 0.111
regulation of nervous system development GO:0051960 264 0.105
regulation of cell proliferation GO:0042127 359 0.103
organelle organization GO:0006996 266 0.093
reproductive process GO:0022414 372 0.087
Fly
multi organism reproductive process GO:0044703 262 0.087
Fly
response to peptide hormone GO:0043434 278 0.087
regulation of cellular component organization GO:0051128 368 0.086
macromolecule catabolic process GO:0009057 58 0.084
neuron projection development GO:0031175 273 0.081
single organism reproductive process GO:0044702 297 0.079
Fly
multicellular organismal reproductive process GO:0048609 233 0.075
Fly
actin filament based process GO:0030029 86 0.075
single organism organelle organization GO:1902589 180 0.073
rna metabolic process GO:0016070 406 0.072
regulation of cell differentiation GO:0045595 320 0.069
trna metabolic process GO:0006399 4 0.066
response to nutrient levels GO:0031667 370 0.065
regulation of neurogenesis GO:0050767 247 0.064
developmental process involved in reproduction GO:0003006 159 0.063
nucleoside metabolic process GO:0009116 179 0.062
cell projection organization GO:0030030 302 0.061
carbohydrate derivative metabolic process GO:1901135 346 0.059
regulation of intracellular signal transduction GO:1902531 218 0.057
intracellular signal transduction GO:0035556 314 0.056
ribonucleotide metabolic process GO:0009259 231 0.054
purine nucleoside metabolic process GO:0042278 169 0.054
single organism catabolic process GO:0044712 283 0.052
multicellular organism reproduction GO:0032504 233 0.052
Fly
neuron differentiation GO:0030182 368 0.052
cellular response to organonitrogen compound GO:0071417 197 0.051
cell cell signaling GO:0007267 335 0.051
actin cytoskeleton organization GO:0030036 73 0.048
regulation of arp2 3 complex mediated actin nucleation GO:0034315 2 0.048
regulation of cell development GO:0060284 263 0.047
response to extracellular stimulus GO:0009991 380 0.047
protein targeting GO:0006605 61 0.046
brain development GO:0007420 247 0.045
ncrna processing GO:0034470 3 0.045
single organism cellular localization GO:1902580 102 0.044
organic acid metabolic process GO:0006082 292 0.044
cellular response to oxygen containing compound GO:1901701 386 0.043
regulation of cell projection organization GO:0031344 175 0.043
defense response GO:0006952 194 0.043
response to cytokine GO:0034097 215 0.041
receptor internalization GO:0031623 14 0.040
aging GO:0007568 241 0.040
intracellular protein transport GO:0006886 79 0.039
response to radiation GO:0009314 137 0.039
single organism intracellular transport GO:1902582 166 0.039
regulation of signal transduction GO:0009966 318 0.039
nucleic acid templated transcription GO:0097659 379 0.039
regulation of anatomical structure size GO:0090066 135 0.039
cellular response to peptide hormone stimulus GO:0071375 120 0.039
ribose phosphate metabolic process GO:0019693 235 0.039
regulation of locomotion GO:0040012 148 0.038
protein phosphorylation GO:0006468 345 0.038
regulation of nucleic acid templated transcription GO:1903506 380 0.037
cellular response to cytokine stimulus GO:0071345 127 0.036
regulation of cell motility GO:2000145 131 0.036
cellular response to insulin stimulus GO:0032869 81 0.035
regulation of synaptic transmission GO:0050804 141 0.035
regulation of synaptic plasticity GO:0048167 70 0.035
regulation of dendrite development GO:0050773 59 0.035
eye development GO:0001654 50 0.035
cellular response to peptide GO:1901653 133 0.035
cellular component morphogenesis GO:0032989 155 0.034
protein dephosphorylation GO:0006470 38 0.034
synaptic transmission GO:0007268 235 0.034
response to oxygen levels GO:0070482 265 0.034
purine containing compound biosynthetic process GO:0072522 85 0.034
positive regulation of cellular component organization GO:0051130 200 0.034
cellular response to stress GO:0033554 269 0.033
cellular component biogenesis GO:0044085 368 0.033
regulation of anatomical structure morphogenesis GO:0022603 141 0.033
centrosome cycle GO:0007098 1 0.032
dephosphorylation GO:0016311 98 0.032
positive regulation of cellular component movement GO:0051272 102 0.031
response to wounding GO:0009611 254 0.031
organic cyclic compound catabolic process GO:1901361 175 0.031
regulation of protein phosphorylation GO:0001932 183 0.031
locomotion GO:0040011 237 0.031
response to growth factor GO:0070848 189 0.031
negative regulation of cellular biosynthetic process GO:0031327 161 0.031
regulation of cellular component movement GO:0051270 150 0.031
cellular component assembly GO:0022607 360 0.030
cell motility GO:0048870 202 0.030
positive regulation of cell motility GO:2000147 97 0.030
purine ribonucleotide metabolic process GO:0009150 227 0.030
nucleobase containing small molecule metabolic process GO:0055086 316 0.030
purine nucleotide biosynthetic process GO:0006164 83 0.030
response to external biotic stimulus GO:0043207 221 0.030
macromolecular complex subunit organization GO:0043933 339 0.029
spindle organization GO:0007051 2 0.029
response to biotic stimulus GO:0009607 226 0.029
negative regulation of cell communication GO:0010648 158 0.028
cell part morphogenesis GO:0032990 123 0.028
positive regulation of cell death GO:0010942 184 0.028
reproduction GO:0000003 245 0.028
Fly
localization of cell GO:0051674 202 0.027
purine ribonucleoside metabolic process GO:0046128 168 0.027
positive regulation of cell differentiation GO:0045597 217 0.027
purine ribonucleotide biosynthetic process GO:0009152 81 0.027
regulation of neuron projection development GO:0010975 161 0.027
response to hexose GO:0009746 144 0.026
centrosome localization GO:0051642 1 0.026
central nervous system development GO:0007417 311 0.026
gamete generation GO:0007276 124 0.026
Fly
positive regulation of cell proliferation GO:0008284 249 0.026
nucleoside monophosphate metabolic process GO:0009123 93 0.026
receptor mediated endocytosis GO:0006898 42 0.026
negative regulation of gene expression GO:0010629 199 0.025
sexual reproduction GO:0019953 148 0.025
Fly
protein transport GO:0015031 132 0.025
positive regulation of response to stimulus GO:0048584 285 0.025
single organism biosynthetic process GO:0044711 342 0.025
negative regulation of signaling GO:0023057 157 0.025
meiotic cell cycle process GO:1903046 3 0.025
heterocycle catabolic process GO:0046700 167 0.025
cellular macromolecule localization GO:0070727 122 0.025
gtp metabolic process GO:0046039 72 0.024
growth GO:0040007 165 0.024
regulation of secretion by cell GO:1903530 208 0.024
establishment of protein localization GO:0045184 141 0.024
positive regulation of gene expression GO:0010628 244 0.024
Fly
tissue development GO:0009888 252 0.024
Fly
transcription from rna polymerase ii promoter GO:0006366 252 0.024
positive regulation of cell migration GO:0030335 96 0.024
ribonucleoside metabolic process GO:0009119 174 0.024
anatomical structure morphogenesis GO:0009653 298 0.024
Fly
regulation of phosphate metabolic process GO:0019220 349 0.024
response to glucose GO:0009749 136 0.024
cell cycle GO:0007049 101 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.023
cellular response to gonadotropin stimulus GO:0071371 17 0.023
regulation of protein phosphatase type 2a activity GO:0034047 2 0.023
regulation of stem cell differentiation GO:2000736 2 0.023
regulation of multicellular organismal development GO:2000026 376 0.023
protein localization GO:0008104 191 0.023
sulfur compound metabolic process GO:0006790 70 0.023
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.023
nucleoside phosphate metabolic process GO:0006753 283 0.023
regulation of dendritic spine development GO:0060998 16 0.022
regulation of response to stress GO:0080134 126 0.022
small gtpase mediated signal transduction GO:0007264 36 0.022
purine nucleoside monophosphate biosynthetic process GO:0009127 20 0.022
amine metabolic process GO:0009308 38 0.022
response to hypoxia GO:0001666 231 0.022
cellular response to hormone stimulus GO:0032870 247 0.022
carbohydrate derivative catabolic process GO:1901136 147 0.022
transmembrane transport GO:0055085 412 0.022
head development GO:0060322 247 0.022
macromolecule localization GO:0033036 252 0.022
negative regulation of response to stimulus GO:0048585 155 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.021
Fly
cytoskeleton organization GO:0007010 111 0.021
negative regulation of cellular metabolic process GO:0031324 281 0.021
nucleotide metabolic process GO:0009117 279 0.021
cofactor biosynthetic process GO:0051188 28 0.021
apoptotic process GO:0006915 381 0.021
response to other organism GO:0051707 220 0.021
purine nucleotide catabolic process GO:0006195 136 0.020
cell migration GO:0016477 197 0.020
multi multicellular organism process GO:0044706 138 0.020
organ regeneration GO:0031100 101 0.020
glycosyl compound metabolic process GO:1901657 182 0.020
organonitrogen compound biosynthetic process GO:1901566 167 0.020
cell morphogenesis GO:0000902 142 0.020
regulation of phosphorus metabolic process GO:0051174 349 0.019
smooth muscle cell migration GO:0014909 36 0.019
regulation of phosphorylation GO:0042325 248 0.019
cellular response to growth factor stimulus GO:0071363 162 0.019
negative regulation of molecular function GO:0044092 133 0.019
cellular protein localization GO:0034613 122 0.019
er associated ubiquitin dependent protein catabolic process GO:0030433 1 0.019
nucleobase containing compound catabolic process GO:0034655 152 0.019
response to nutrient GO:0007584 248 0.019
regulation of neuron differentiation GO:0045664 208 0.019
synaptic growth at neuromuscular junction GO:0051124 1 0.019
carbohydrate derivative biosynthetic process GO:1901137 124 0.018
positive regulation of catabolic process GO:0009896 78 0.018
purine containing compound metabolic process GO:0072521 253 0.018
regeneration GO:0031099 163 0.018
male gamete generation GO:0048232 99 0.018
Fly
cellular amine metabolic process GO:0044106 38 0.017
response to toxic substance GO:0009636 133 0.017
cellular amino acid metabolic process GO:0006520 107 0.017
response to decreased oxygen levels GO:0036293 237 0.017
arp2 3 complex mediated actin nucleation GO:0034314 2 0.017
positive regulation of biosynthetic process GO:0009891 319 0.017
Fly
response to interleukin 1 GO:0070555 55 0.017
response to axon injury GO:0048678 59 0.017
ribonucleoside catabolic process GO:0042454 126 0.017
negative regulation of cellular component organization GO:0051129 83 0.017
polyamine biosynthetic process GO:0006596 4 0.016
cell cycle g1 s phase transition GO:0044843 13 0.016
cell morphogenesis involved in differentiation GO:0000904 119 0.016
rna catabolic process GO:0006401 3 0.016
response to carbohydrate GO:0009743 183 0.016
purine nucleoside biosynthetic process GO:0042451 21 0.016
cardiac ventricle development GO:0003231 1 0.016
proteolysis GO:0006508 175 0.016
programmed cell death GO:0012501 392 0.016
Fly
positive regulation of cell communication GO:0010647 271 0.016
signal release GO:0023061 145 0.016
embryonic pattern specification GO:0009880 1 0.016
regulation of actin nucleation GO:0051125 2 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.016
positive regulation of phosphorylation GO:0042327 177 0.016
protein complex subunit organization GO:0071822 302 0.016
positive regulation of apoptotic process GO:0043065 154 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.016
regulation of proteasomal protein catabolic process GO:0061136 4 0.016
circulatory system development GO:0072359 134 0.016
protein oligomerization GO:0051259 191 0.016
amp metabolic process GO:0046033 8 0.016
cytoplasmic transport GO:0016482 115 0.016
organophosphate metabolic process GO:0019637 370 0.016
centrosome organization GO:0051297 1 0.015
negative regulation of biosynthetic process GO:0009890 168 0.015
positive regulation of locomotion GO:0040017 102 0.015
regulation of rna metabolic process GO:0051252 391 0.015
behavior GO:0007610 205 0.015
positive regulation of protein dephosphorylation GO:0035307 4 0.015
mapk cascade GO:0000165 140 0.015
regulation of cellular amine metabolic process GO:0033238 8 0.015
cellular nitrogen compound catabolic process GO:0044270 163 0.015
chemical homeostasis GO:0048878 292 0.015
mesoderm morphogenesis GO:0048332 1 0.015
anatomical structure formation involved in morphogenesis GO:0048646 83 0.015
nucleoside triphosphate metabolic process GO:0009141 144 0.014
mesenchymal cell proliferation GO:0010463 4 0.014
regulation of cell migration GO:0030334 128 0.014
negative regulation of multicellular organismal process GO:0051241 203 0.014
secretion by cell GO:0032940 248 0.014
regulation of apoptotic process GO:0042981 335 0.014
nucleobase biosynthetic process GO:0046112 2 0.014
regulation of axon extension GO:0030516 24 0.014
positive regulation of neuron differentiation GO:0045666 126 0.014
embryonic axis specification GO:0000578 1 0.014
regulation of cellular localization GO:0060341 263 0.014
aromatic compound catabolic process GO:0019439 168 0.014
protein complex assembly GO:0006461 263 0.014
behavioral response to ethanol GO:0048149 1 0.014
regulation of programmed cell death GO:0043067 341 0.014
positive regulation of multicellular organismal process GO:0051240 387 0.014
peptide transport GO:0015833 97 0.014
divalent metal ion transport GO:0070838 132 0.013
cellular component movement GO:0006928 248 0.013
rna biosynthetic process GO:0032774 380 0.013
regulation of cellular response to stress GO:0080135 49 0.013
nucleoside phosphate catabolic process GO:1901292 140 0.013
positive regulation of signaling GO:0023056 270 0.013
cellular process involved in reproduction in multicellular organism GO:0022412 35 0.013
eye morphogenesis GO:0048592 4 0.013
cellular response to external stimulus GO:0071496 118 0.013
regulation of p38mapk cascade GO:1900744 1 0.013
positive regulation of cellular catabolic process GO:0031331 71 0.013
intracellular transport GO:0046907 185 0.013
axis specification GO:0009798 4 0.013
carbohydrate homeostasis GO:0033500 75 0.013
organophosphate catabolic process GO:0046434 148 0.013
purine ribonucleotide catabolic process GO:0009154 136 0.013
organ formation GO:0048645 3 0.013
positive regulation of signal transduction GO:0009967 175 0.013
regulation of protein transport GO:0051223 68 0.013
muscle cell migration GO:0014812 36 0.013
regulation of vesicle mediated transport GO:0060627 81 0.013
muscle tissue development GO:0060537 58 0.013
regulation of molecular function GO:0065009 398 0.013
regulation of cell maturation GO:1903429 3 0.013
positive regulation of phosphorus metabolic process GO:0010562 262 0.013
response to alkaloid GO:0043279 132 0.013
hormone transport GO:0009914 121 0.013
negative regulation of phosphorus metabolic process GO:0010563 80 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.012
negative regulation of hydrogen peroxide metabolic process GO:0010727 2 0.012
cellular response to steroid hormone stimulus GO:0071383 93 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
anterior posterior pattern specification GO:0009952 1 0.012
organophosphate biosynthetic process GO:0090407 143 0.012
nucleotide biosynthetic process GO:0009165 98 0.012
amide transport GO:0042886 105 0.012
protein heterooligomerization GO:0051291 89 0.012
negative regulation of phosphorylation GO:0042326 57 0.012
g protein coupled receptor signaling pathway GO:0007186 242 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.012
negative regulation of cell differentiation GO:0045596 99 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
spermatogenesis GO:0007283 99 0.012
Fly
nucleoside monophosphate biosynthetic process GO:0009124 28 0.012
response to inorganic substance GO:0010035 377 0.012
positive regulation of smooth muscle cell migration GO:0014911 27 0.012
purine containing compound catabolic process GO:0072523 138 0.012
nucleoside catabolic process GO:0009164 126 0.012
negative regulation of cell development GO:0010721 82 0.012
sensory organ development GO:0007423 74 0.012
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.012
protein tetramerization GO:0051262 38 0.012
regulation of smooth muscle cell proliferation GO:0048660 75 0.012
nitrogen compound transport GO:0071705 229 0.012
secretion GO:0046903 307 0.012
small molecule biosynthetic process GO:0044283 124 0.012
ribonucleoside monophosphate metabolic process GO:0009161 88 0.012
positive regulation of hydrolase activity GO:0051345 86 0.012
macroautophagy GO:0016236 4 0.012
mitotic spindle organization GO:0007052 2 0.012
cytoskeleton dependent cytokinesis GO:0061640 2 0.012
actin filament depolymerization GO:0030042 3 0.012
regulation of protein kinase activity GO:0045859 105 0.012
regulation of protein metabolic process GO:0051246 289 0.011
Fly
cardiovascular system development GO:0072358 134 0.011
cell cycle process GO:0022402 57 0.011
positive regulation of intracellular signal transduction GO:1902533 138 0.011
positive regulation of phosphate metabolic process GO:0045937 262 0.011
positive regulation of neuron projection development GO:0010976 99 0.011
establishment of protein localization to organelle GO:0072594 44 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 1 0.011
oxoacid metabolic process GO:0043436 290 0.011
purine nucleobase metabolic process GO:0006144 4 0.011
glucose homeostasis GO:0042593 75 0.011
mitochondrion organization GO:0007005 35 0.011
positive regulation of molecular function GO:0044093 230 0.011
homeostatic process GO:0042592 331 0.011
cellular response to oxygen levels GO:0071453 60 0.011
response to antibiotic GO:0046677 39 0.011
response to oxidative stress GO:0006979 186 0.011
negative regulation of nervous system development GO:0051961 79 0.011
carboxylic acid metabolic process GO:0019752 289 0.011
response to ethanol GO:0045471 162 0.011
regulation of establishment of protein localization GO:0070201 69 0.011
signal transduction by phosphorylation GO:0023014 144 0.011
guanosine containing compound catabolic process GO:1901069 71 0.011
microtubule based process GO:0007017 36 0.011
nucleotide catabolic process GO:0009166 139 0.011
coenzyme biosynthetic process GO:0009108 22 0.011
chromosome segregation GO:0007059 2 0.011
regulation of cell growth GO:0001558 85 0.011
purine nucleoside catabolic process GO:0006152 124 0.011
endocytosis GO:0006897 84 0.011
cellular response to interleukin 1 GO:0071347 37 0.011
cell fate commitment involved in pattern specification GO:0060581 2 0.011
regulation of behavior GO:0050795 61 0.011
cellular response to alcohol GO:0097306 87 0.011
regulation of hydrolase activity GO:0051336 143 0.010
neuron development GO:0048666 286 0.010
coenzyme metabolic process GO:0006732 86 0.010
transcription dna templated GO:0006351 377 0.010
positive regulation of cellular amine metabolic process GO:0033240 3 0.010
regulation of organelle organization GO:0033043 80 0.010
developmental growth GO:0048589 100 0.010
detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 4 0.010
ribonucleoside biosynthetic process GO:0042455 25 0.010
carboxylic acid biosynthetic process GO:0046394 83 0.010
positive regulation of phosphoprotein phosphatase activity GO:0032516 3 0.010
p38mapk cascade GO:0038066 1 0.010
negative regulation of metabolic process GO:0009892 331 0.010
regulation of smoothened signaling pathway GO:0008589 2 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.010
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.010
cytosolic calcium ion homeostasis GO:0051480 140 0.010
regulation of extent of cell growth GO:0061387 25 0.010
regulation of transferase activity GO:0051338 123 0.010
cellular chemical homeostasis GO:0055082 247 0.010
regulation of cell morphogenesis GO:0022604 77 0.010
regulation of rna biosynthetic process GO:2001141 381 0.010

Eif4e disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.029
disease of anatomical entity DOID:7 0 0.029
nervous system disease DOID:863 0 0.029
myopathy DOID:423 0 0.021
muscular disease DOID:0080000 0 0.021
muscular dystrophy DOID:9884 0 0.021
musculoskeletal system disease DOID:17 0 0.021
muscle tissue disease DOID:66 0 0.021
disease of metabolism DOID:0014667 0 0.016
inherited metabolic disorder DOID:655 0 0.016