Rattus norvegicus

197 known processes

Tp53

tumor protein p53

(Aliases: MGC112612,p53,Trp53)

Tp53 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to inorganic substance GO:0010035 377 0.671
rna metabolic process GO:0016070 406 0.438
response to oxygen levels GO:0070482 265 0.422
regulation of programmed cell death GO:0043067 341 0.405
regulation of transcription dna templated GO:0006355 374 0.371
cellular response to endogenous stimulus GO:0071495 377 0.356
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.355
cellular response to stress GO:0033554 269 0.349
response to acid chemical GO:0001101 222 0.348
regulation of cell proliferation GO:0042127 359 0.312
cellular response to organic cyclic compound GO:0071407 202 0.300
regulation of apoptotic process GO:0042981 335 0.297
programmed cell death GO:0012501 392 0.290
regulation of protein metabolic process GO:0051246 289 0.262
Rat
positive regulation of response to stimulus GO:0048584 285 0.258
Human Rat
negative regulation of biosynthetic process GO:0009890 168 0.251
cellular amino acid metabolic process GO:0006520 107 0.240
regulation of phosphate metabolic process GO:0019220 349 0.238
Rat
response to hypoxia GO:0001666 231 0.213
Human
cellular response to oxygen containing compound GO:1901701 386 0.209
response to decreased oxygen levels GO:0036293 237 0.204
Human
negative regulation of apoptotic process GO:0043066 181 0.193
Human
apoptotic process GO:0006915 381 0.188
homeostatic process GO:0042592 331 0.185
negative regulation of gene expression GO:0010629 199 0.182
positive regulation of cellular biosynthetic process GO:0031328 295 0.179
transcription dna templated GO:0006351 377 0.178
negative regulation of response to stimulus GO:0048585 155 0.178
cellular response to hormone stimulus GO:0032870 247 0.175
positive regulation of cellular protein metabolic process GO:0032270 167 0.168
Rat
carboxylic acid metabolic process GO:0019752 289 0.164
response to nutrient GO:0007584 248 0.160
positive regulation of phosphorus metabolic process GO:0010562 262 0.158
Rat
t cell homeostasis GO:0043029 2 0.155
response to peptide hormone GO:0043434 278 0.154
regulation of rna metabolic process GO:0051252 391 0.153
positive regulation of cell death GO:0010942 184 0.150
cellular response to organonitrogen compound GO:0071417 197 0.149
oxoacid metabolic process GO:0043436 290 0.146
organelle organization GO:0006996 266 0.144
Human
positive regulation of gene expression GO:0010628 244 0.140
transcription from rna polymerase ii promoter GO:0006366 252 0.139
response to extracellular stimulus GO:0009991 380 0.139
negative regulation of metabolic process GO:0009892 331 0.139
response to corticosteroid GO:0031960 235 0.138
macromolecular complex subunit organization GO:0043933 339 0.135
Human
protein complex biogenesis GO:0070271 263 0.131
Human
negative regulation of signaling GO:0023057 157 0.131
regulation of cellular protein metabolic process GO:0032268 267 0.131
Rat
macromolecular complex assembly GO:0065003 273 0.130
Human
regulation of immune system process GO:0002682 123 0.127
regulation of homeostatic process GO:0032844 101 0.127
organic acid metabolic process GO:0006082 292 0.126
positive regulation of molecular function GO:0044093 230 0.126
Rat
reproduction GO:0000003 245 0.122
Rat
nucleobase containing small molecule metabolic process GO:0055086 316 0.122
rna biosynthetic process GO:0032774 380 0.121
intracellular signal transduction GO:0035556 314 0.121
Human Rat
regulation of protein phosphorylation GO:0001932 183 0.120
Rat
cellular response to peptide hormone stimulus GO:0071375 120 0.119
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.119
ribonucleoside metabolic process GO:0009119 174 0.119
cellular response to cytokine stimulus GO:0071345 127 0.118
positive regulation of cell proliferation GO:0008284 249 0.118
negative regulation of macromolecule metabolic process GO:0010605 260 0.116
negative regulation of nucleic acid templated transcription GO:1903507 117 0.115
response to cytokine GO:0034097 215 0.113
response to estrogen GO:0043627 232 0.113
regulation of signal transduction GO:0009966 318 0.112
Human Rat
regulation of phosphorylation GO:0042325 248 0.112
Rat
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.111
tissue development GO:0009888 252 0.109
response to peptide GO:1901652 292 0.108
regulation of leukocyte activation GO:0002694 45 0.106
single organism organelle organization GO:1902589 180 0.105
leukocyte homeostasis GO:0001776 7 0.104
immune response GO:0006955 104 0.101
nucleic acid templated transcription GO:0097659 379 0.100
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.100
negative regulation of cellular metabolic process GO:0031324 281 0.099
organophosphate metabolic process GO:0019637 370 0.099
single organism reproductive process GO:0044702 297 0.097
Rat
response to estradiol GO:0032355 164 0.097
protein complex assembly GO:0006461 263 0.096
Human
response to ethanol GO:0045471 162 0.096
regulation of molecular function GO:0065009 398 0.095
Rat
aging GO:0007568 241 0.093
negative regulation of cell proliferation GO:0008285 119 0.093
reproductive process GO:0022414 372 0.092
Rat
response to carbohydrate GO:0009743 183 0.092
response to glucocorticoid GO:0051384 223 0.092
negative regulation of rna metabolic process GO:0051253 123 0.091
cellular response to tumor necrosis factor GO:0071356 46 0.091
organonitrogen compound biosynthetic process GO:1901566 167 0.091
carbohydrate derivative metabolic process GO:1901135 346 0.091
leukocyte cell cell adhesion GO:0007159 4 0.090
multicellular organism reproduction GO:0032504 233 0.087
Rat
positive regulation of programmed cell death GO:0043068 157 0.086
cellular response to lipid GO:0071396 201 0.085
gland development GO:0048732 155 0.085
regulation of nucleic acid templated transcription GO:1903506 380 0.084
organ regeneration GO:0031100 101 0.084
positive regulation of phosphate metabolic process GO:0045937 262 0.084
Rat
neuronal action potential GO:0019228 35 0.084
cellular response to nitrogen compound GO:1901699 210 0.083
protein complex subunit organization GO:0071822 302 0.082
Human
response to hydrogen peroxide GO:0042542 89 0.081
negative regulation of cell differentiation GO:0045596 99 0.081
Rat
reactive oxygen species metabolic process GO:0072593 37 0.081
Human
positive regulation of cell communication GO:0010647 271 0.081
Human Rat
anatomical structure morphogenesis GO:0009653 298 0.080
single organism intracellular transport GO:1902582 166 0.077
cellular response to peptide GO:1901653 133 0.077
negative regulation of cell communication GO:0010648 158 0.075
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.074
behavior GO:0007610 205 0.074
amine metabolic process GO:0009308 38 0.074
negative regulation of protein metabolic process GO:0051248 114 0.073
immune system process GO:0002376 204 0.072
regulation of cellular amine metabolic process GO:0033238 8 0.072
response to amino acid GO:0043200 75 0.071
response to interleukin 1 GO:0070555 55 0.070
rhythmic process GO:0048511 156 0.070
cellular protein localization GO:0034613 122 0.070
Human
cellular component assembly GO:0022607 360 0.070
Human
regulation of intracellular signal transduction GO:1902531 218 0.069
Human Rat
cellular component biogenesis GO:0044085 368 0.068
Human
neuron projection development GO:0031175 273 0.068
negative regulation of cell death GO:0060548 229 0.067
Human
oxidation reduction process GO:0055114 304 0.066
purine nucleoside monophosphate biosynthetic process GO:0009127 20 0.066
cellular macromolecule localization GO:0070727 122 0.064
Human
nucleoside metabolic process GO:0009116 179 0.063
cellular response to reactive oxygen species GO:0034614 55 0.063
peptide biosynthetic process GO:0043043 3 0.063
leukocyte activation GO:0045321 76 0.062
dna metabolic process GO:0006259 96 0.062
signal transduction by phosphorylation GO:0023014 144 0.061
Rat
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.061
regulation of organelle organization GO:0033043 80 0.061
Human
positive regulation of apoptotic process GO:0043065 154 0.061
g protein coupled receptor signaling pathway GO:0007186 242 0.061
positive regulation of protein metabolic process GO:0051247 178 0.061
Rat
tube development GO:0035295 89 0.060
response to nutrient levels GO:0031667 370 0.059
response to reactive oxygen species GO:0000302 120 0.059
cell migration GO:0016477 197 0.058
cellular response to oxidative stress GO:0034599 76 0.058
Human
single organism membrane organization GO:0044802 74 0.058
response to wounding GO:0009611 254 0.057
response to transition metal nanoparticle GO:1990267 122 0.057
positive regulation of signal transduction GO:0009967 175 0.057
Human Rat
response to oxidative stress GO:0006979 186 0.057
negative regulation of cellular biosynthetic process GO:0031327 161 0.055
single organism cellular localization GO:1902580 102 0.055
protein phosphorylation GO:0006468 345 0.055
Rat
regulation of cellular component organization GO:0051128 368 0.055
Human
regulation of cellular ketone metabolic process GO:0010565 27 0.055
response to tumor necrosis factor GO:0034612 56 0.054
regulation of cell activation GO:0050865 50 0.053
lymphocyte homeostasis GO:0002260 2 0.053
embryo development GO:0009790 49 0.052
regulation of fc receptor mediated stimulatory signaling pathway GO:0060368 3 0.052
positive regulation of immune system process GO:0002684 90 0.052
multi multicellular organism process GO:0044706 138 0.052
regulation of membrane potential GO:0042391 110 0.052
cellular divalent inorganic cation homeostasis GO:0072503 162 0.051
apoptotic signaling pathway GO:0097190 27 0.050
Human
negative regulation of developmental process GO:0051093 125 0.050
Rat
negative regulation of signal transduction GO:0009968 83 0.050
blood circulation GO:0008015 183 0.050
regulation of cell differentiation GO:0045595 320 0.049
Rat
secretion GO:0046903 307 0.049
negative regulation of transcription from rna polymerase ii promoter GO:0000122 75 0.049
Human
inflammatory response GO:0006954 150 0.048
carbohydrate derivative biosynthetic process GO:1901137 124 0.048
regulation of lipid metabolic process GO:0019216 68 0.048
response to metal ion GO:0010038 253 0.047
neurological system process GO:0050877 219 0.047
ribose phosphate biosynthetic process GO:0046390 87 0.046
muscle system process GO:0003012 115 0.045
regulation of catalytic activity GO:0050790 304 0.044
Rat
intracellular transport GO:0046907 185 0.044
response to ketone GO:1901654 182 0.044
positive regulation of cellular amine metabolic process GO:0033240 3 0.044
mitotic spindle organization GO:0007052 2 0.044
single organism biosynthetic process GO:0044711 342 0.044
negative regulation of transcription dna templated GO:0045892 116 0.043
ribose phosphate metabolic process GO:0019693 235 0.043
positive regulation of intracellular signal transduction GO:1902533 138 0.043
Human Rat
nucleocytoplasmic transport GO:0006913 48 0.043
positive regulation of rna metabolic process GO:0051254 203 0.043
multicellular organismal signaling GO:0035637 44 0.042
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.042
positive regulation of cellular component movement GO:0051272 102 0.041
glycosyl compound metabolic process GO:1901657 182 0.041
positive regulation of protein phosphorylation GO:0001934 135 0.041
Rat
regulation of response to stress GO:0080134 126 0.041
positive regulation of transcription dna templated GO:0045893 197 0.041
cellular amide metabolic process GO:0043603 44 0.041
multicellular organismal reproductive process GO:0048609 233 0.040
Rat
response to electrical stimulus GO:0051602 56 0.040
positive regulation of kinase activity GO:0033674 77 0.040
Rat
cellular response to interleukin 1 GO:0071347 37 0.039
intracellular receptor signaling pathway GO:0030522 35 0.039
alpha amino acid metabolic process GO:1901605 71 0.039
heterotypic cell cell adhesion GO:0034113 2 0.039
positive regulation of developmental process GO:0051094 283 0.039
Rat
multi organism reproductive process GO:0044703 262 0.039
Rat
nucleotide metabolic process GO:0009117 279 0.039
regulation of locomotion GO:0040012 148 0.038
response to mineralocorticoid GO:0051385 49 0.038
regulation of heterotypic cell cell adhesion GO:0034114 2 0.038
cellular homeostasis GO:0019725 252 0.038
regulation of cellular amino acid metabolic process GO:0006521 2 0.037
cellular component movement GO:0006928 248 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.037
purine nucleoside monophosphate metabolic process GO:0009126 84 0.037
ribonucleotide biosynthetic process GO:0009260 85 0.037
positive regulation of biosynthetic process GO:0009891 319 0.037
regulation of system process GO:0044057 208 0.037
cellular cation homeostasis GO:0030003 180 0.037
cellular amine metabolic process GO:0044106 38 0.037
female gonad development GO:0008585 53 0.036
positive regulation of nucleotide metabolic process GO:0045981 91 0.036
cellular response to abiotic stimulus GO:0071214 85 0.036
Human
response to growth factor GO:0070848 189 0.036
calcium ion homeostasis GO:0055074 162 0.036
regulation of reactive oxygen species metabolic process GO:2000377 26 0.035
Human
regulation of mrna splicing via spliceosome GO:0048024 3 0.035
protein localization GO:0008104 191 0.035
Human
cellular response to oxygen levels GO:0071453 60 0.035
Human
regulation of phosphorus metabolic process GO:0051174 349 0.035
Rat
positive regulation of nucleic acid templated transcription GO:1903508 197 0.035
cellular response to growth factor stimulus GO:0071363 162 0.035
cellular chemical homeostasis GO:0055082 247 0.034
nucleoside monophosphate metabolic process GO:0009123 93 0.034
nucleoside phosphate biosynthetic process GO:1901293 102 0.034
negative regulation of cytokine production GO:0001818 16 0.034
gastrulation GO:0007369 2 0.034
membrane organization GO:0061024 94 0.034
ribonucleotide metabolic process GO:0009259 231 0.034
axis specification GO:0009798 4 0.034
protein homooligomerization GO:0051260 91 0.033
myeloid leukocyte activation GO:0002274 36 0.033
neuron death GO:0070997 127 0.033
positive regulation of secretion by cell GO:1903532 128 0.033
actin filament based process GO:0030029 86 0.032
nucleoside monophosphate biosynthetic process GO:0009124 28 0.032
cellular response to external stimulus GO:0071496 118 0.032
Human
ion homeostasis GO:0050801 212 0.032
cellular response to steroid hormone stimulus GO:0071383 93 0.032
purine ribonucleoside monophosphate biosynthetic process GO:0009168 20 0.031
chemical homeostasis GO:0048878 292 0.031
cell cycle GO:0007049 101 0.031
regulation of cell motility GO:2000145 131 0.031
proteolysis GO:0006508 175 0.031
organic substance catabolic process GO:1901575 316 0.031
positive regulation of rna biosynthetic process GO:1902680 197 0.031
response to vitamin GO:0033273 131 0.031
regulation of cytokine production GO:0001817 56 0.030
response to bacterium GO:0009617 200 0.030
response to purine containing compound GO:0014074 126 0.030
regulation of protein import into nucleus GO:0042306 24 0.030
purine containing compound metabolic process GO:0072521 253 0.030
single organism catabolic process GO:0044712 283 0.030
response to glucose GO:0009749 136 0.030
amide biosynthetic process GO:0043604 10 0.030
ovulation cycle process GO:0022602 50 0.030
central nervous system development GO:0007417 311 0.029
Rat
cellular ion homeostasis GO:0006873 184 0.029
response to organophosphorus GO:0046683 102 0.029
nucleotide biosynthetic process GO:0009165 98 0.029
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 10 0.029
response to hexose GO:0009746 144 0.029
protein localization to organelle GO:0033365 57 0.029
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.029
response to external biotic stimulus GO:0043207 221 0.028
kidney development GO:0001822 67 0.028
Rat
cation transport GO:0006812 382 0.028
reactive oxygen species biosynthetic process GO:1903409 8 0.028
purine nucleotide metabolic process GO:0006163 229 0.028
protein targeting to nucleus GO:0044744 35 0.028
regulation of rna biosynthetic process GO:2001141 381 0.028
gonad development GO:0008406 104 0.028
response to insulin GO:0032868 133 0.028
regulation of vesicle mediated transport GO:0060627 81 0.028
organophosphate biosynthetic process GO:0090407 143 0.028
protein transport GO:0015031 132 0.028
protein maturation GO:0051604 68 0.028
homeostasis of number of cells GO:0048872 10 0.028
cell cycle g1 s phase transition GO:0044843 13 0.027
Human
organonitrogen compound catabolic process GO:1901565 179 0.027
cellular ketone metabolic process GO:0042180 51 0.027
divalent inorganic cation homeostasis GO:0072507 165 0.027
response to mechanical stimulus GO:0009612 134 0.027
brain development GO:0007420 247 0.027
mapk cascade GO:0000165 140 0.026
Rat
regulation of neurogenesis GO:0050767 247 0.026
Rat
cytokine production GO:0001816 61 0.026
fc receptor mediated stimulatory signaling pathway GO:0002431 3 0.026
ovulation cycle GO:0042698 67 0.026
positive regulation of release of cytochrome c from mitochondria GO:0090200 3 0.026
Human
cellular metal ion homeostasis GO:0006875 172 0.026
peptidyl amino acid modification GO:0018193 126 0.026
organic acid biosynthetic process GO:0016053 83 0.026
actin filament bundle organization GO:0061572 19 0.026
response to biotic stimulus GO:0009607 226 0.026
Human
biological adhesion GO:0022610 110 0.026
positive regulation of signaling GO:0023056 270 0.026
Human Rat
purine nucleotide biosynthetic process GO:0006164 83 0.025
embryonic pattern specification GO:0009880 1 0.025
positive regulation of transport GO:0051050 245 0.025
cell cycle checkpoint GO:0000075 2 0.025
Human
purine ribonucleotide biosynthetic process GO:0009152 81 0.025
small molecule biosynthetic process GO:0044283 124 0.025
cell cell signaling GO:0007267 335 0.025
liver development GO:0001889 90 0.025
cellular response to insulin stimulus GO:0032869 81 0.025
response to molecule of bacterial origin GO:0002237 194 0.025
negative regulation of rna biosynthetic process GO:1902679 118 0.025
single organism carbohydrate metabolic process GO:0044723 118 0.025
ribonucleoside monophosphate metabolic process GO:0009161 88 0.025
chemosensory behavior GO:0007635 2 0.025
regulation of cell migration GO:0030334 128 0.024
cell cycle process GO:0022402 57 0.024
Human
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.024
purine ribonucleoside biosynthetic process GO:0046129 21 0.024
negative regulation of cellular protein metabolic process GO:0032269 106 0.024
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 1 0.024
Human
positive regulation of multicellular organismal process GO:0051240 387 0.024
Rat
neuron differentiation GO:0030182 368 0.024
Rat
chromatin remodeling GO:0006338 3 0.023
positive regulation of protein modification process GO:0031401 142 0.023
Rat
regulation of protein localization GO:0032880 81 0.023
negative regulation of programmed cell death GO:0043069 183 0.023
Human
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.023
actin cytoskeleton organization GO:0030036 73 0.023
regulation of protein targeting GO:1903533 28 0.023
cytoplasmic transport GO:0016482 115 0.023
endomembrane system organization GO:0010256 48 0.023
lymphocyte proliferation GO:0046651 29 0.023
reactive nitrogen species metabolic process GO:2001057 1 0.023
carbohydrate metabolic process GO:0005975 130 0.023
gland morphogenesis GO:0022612 12 0.023
regulation of cell cycle GO:0051726 73 0.023
developmental process involved in reproduction GO:0003006 159 0.022
hepaticobiliary system development GO:0061008 90 0.022
gamete generation GO:0007276 124 0.022
Rat
protein targeting GO:0006605 61 0.022
sexual reproduction GO:0019953 148 0.022
Rat
female sex differentiation GO:0046660 59 0.022
glycosaminoglycan biosynthetic process GO:0006024 4 0.022
response to gamma radiation GO:0010332 24 0.022
Human
phospholipid metabolic process GO:0006644 61 0.021
cytoskeleton organization GO:0007010 111 0.021
vesicle mediated transport GO:0016192 181 0.021
regulation of reactive oxygen species biosynthetic process GO:1903426 5 0.021
positive regulation of cell activation GO:0050867 34 0.021
regulation of transcription regulatory region dna binding GO:2000677 4 0.021
purine ribonucleoside metabolic process GO:0046128 168 0.021
regulation of cellular component movement GO:0051270 150 0.021
regulation of transferase activity GO:0051338 123 0.021
Rat
cell type specific apoptotic process GO:0097285 134 0.021
Human
regulation of secretion by cell GO:1903530 208 0.021
response to other organism GO:0051707 220 0.020
negative regulation of phosphate metabolic process GO:0045936 80 0.020
positive regulation of secretion GO:0051047 140 0.020
regulation of cellular localization GO:0060341 263 0.020
response to monosaccharide GO:0034284 159 0.020
regulation of protein kinase activity GO:0045859 105 0.020
Rat
asymmetric protein localization GO:0008105 2 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.020
spindle organization GO:0007051 2 0.020
positive regulation of heterotypic cell cell adhesion GO:0034116 1 0.020
macromolecule localization GO:0033036 252 0.020
Human
positive regulation of transferase activity GO:0051347 81 0.020
Rat
positive regulation of reactive oxygen species metabolic process GO:2000379 16 0.020
Human
cellular nitrogen compound catabolic process GO:0044270 163 0.020
glial cell apoptotic process GO:0034349 8 0.020
Human
fertilization GO:0009566 3 0.019
regulation of response to wounding GO:1903034 69 0.019
cellular modified amino acid metabolic process GO:0006575 61 0.019
cellular response to acid chemical GO:0071229 75 0.019
cell projection organization GO:0030030 302 0.019
muscle cell proliferation GO:0033002 84 0.019
regulation of protein modification process GO:0031399 194 0.019
Rat
meiotic cell cycle process GO:1903046 3 0.019
regulation of cell development GO:0060284 263 0.019
Rat
serine family amino acid biosynthetic process GO:0009070 4 0.019
leukocyte differentiation GO:0002521 30 0.019
response to transforming growth factor beta GO:0071559 46 0.019
cellular calcium ion homeostasis GO:0006874 160 0.019
regulation of intracellular transport GO:0032386 65 0.018
chromosome organization GO:0051276 36 0.018
Human
cellular macromolecular complex assembly GO:0034622 58 0.018
positive regulation of cellular component organization GO:0051130 200 0.018
Human
chromatin assembly or disassembly GO:0006333 1 0.018
Human
cellular response to fluid shear stress GO:0071498 4 0.018
peptide metabolic process GO:0006518 32 0.018
secretion by cell GO:0032940 248 0.018
positive regulation of protein transport GO:0051222 41 0.018
carboxylic acid biosynthetic process GO:0046394 83 0.018
regulation of interferon gamma production GO:0032649 3 0.018
mitotic cell cycle process GO:1903047 35 0.018
Human
regulation of actin cytoskeleton organization GO:0032956 30 0.018
cellular amino acid biosynthetic process GO:0008652 32 0.018
sex differentiation GO:0007548 113 0.018
transmembrane transport GO:0055085 412 0.018
digestive system development GO:0055123 41 0.018
cation homeostasis GO:0055080 195 0.018
negative regulation of immune system process GO:0002683 39 0.018
regulation of ion transport GO:0043269 245 0.018
mrna processing GO:0006397 14 0.017
hyaluronan metabolic process GO:0030212 12 0.017
purine ribonucleotide metabolic process GO:0009150 227 0.017
endocytosis GO:0006897 84 0.017
negative regulation of multicellular organismal process GO:0051241 203 0.017
Rat
epithelium development GO:0060429 96 0.017
muscle structure development GO:0061061 87 0.017
regulation of muscle system process GO:0090257 79 0.017
response to activity GO:0014823 73 0.017
positive regulation of dna metabolic process GO:0051054 39 0.017
regeneration GO:0031099 163 0.017
positive regulation of organelle organization GO:0010638 48 0.017
Human
negative regulation of mitotic cell cycle phase transition GO:1901991 3 0.017
Human
tissue morphogenesis GO:0048729 22 0.017
female pregnancy GO:0007565 122 0.017
aromatic compound catabolic process GO:0019439 168 0.017
response to radiation GO:0009314 137 0.017
regulation of mononuclear cell proliferation GO:0032944 26 0.017
regulation of anatomical structure size GO:0090066 135 0.017
peptidyl tyrosine modification GO:0018212 72 0.017
negative regulation of transport GO:0051051 136 0.017
regulation of cell growth GO:0001558 85 0.017
Human
leukocyte migration GO:0050900 38 0.016
circulatory system process GO:0003013 183 0.016
generation of precursor metabolites and energy GO:0006091 62 0.016
positive regulation of smooth muscle cell proliferation GO:0048661 51 0.016
positive regulation of protein kinase activity GO:0045860 73 0.016
Rat
syncytium formation by plasma membrane fusion GO:0000768 3 0.016
embryonic neurocranium morphogenesis GO:0048702 2 0.016
response to fatty acid GO:0070542 65 0.016
protein oligomerization GO:0051259 191 0.016
Human
regulation of metanephros development GO:0072215 4 0.016
response to camp GO:0051591 91 0.016
cell morphogenesis involved in differentiation GO:0000904 119 0.016
positive regulation of cytoplasmic transport GO:1903651 32 0.016
purine containing compound biosynthetic process GO:0072522 85 0.016
cytosolic calcium ion homeostasis GO:0051480 140 0.016
innate immune response GO:0045087 35 0.016
digestive tract development GO:0048565 39 0.016
reproductive structure development GO:0048608 128 0.016
cellular response to hydrogen peroxide GO:0070301 42 0.016
purine nucleoside triphosphate metabolic process GO:0009144 141 0.016
cell motility GO:0048870 202 0.016
mitochondrial transport GO:0006839 19 0.016
intracellular protein transport GO:0006886 79 0.016
blood vessel development GO:0001568 69 0.016
sulfur compound metabolic process GO:0006790 70 0.016
regulation of mapk cascade GO:0043408 116 0.016
Rat
protein import into nucleus GO:0006606 35 0.016
wound healing GO:0042060 122 0.016
response to toxic substance GO:0009636 133 0.016
Human
regulation of cellular response to stress GO:0080135 49 0.015
positive regulation of mesenchymal cell proliferation GO:0002053 4 0.015
regulation of establishment of protein localization GO:0070201 69 0.015
regulation of leukocyte proliferation GO:0070663 26 0.015
positive regulation of catalytic activity GO:0043085 184 0.015
Rat
single organism behavior GO:0044708 130 0.015
kidney mesenchyme development GO:0072074 2 0.015
tube morphogenesis GO:0035239 23 0.015
nucleoside phosphate metabolic process GO:0006753 283 0.015
programmed necrotic cell death GO:0097300 2 0.015
regulation of cytoskeleton organization GO:0051493 49 0.015
immune effector process GO:0002252 53 0.015
triglyceride homeostasis GO:0070328 2 0.015
cellular response to amino acid starvation GO:0034198 1 0.015
cytokine biosynthetic process GO:0042089 3 0.015
negative regulation of molecular function GO:0044092 133 0.015
hematopoietic or lymphoid organ development GO:0048534 36 0.015
heart morphogenesis GO:0003007 3 0.015
regulation of metal ion transport GO:0010959 118 0.015
peptidyl tyrosine phosphorylation GO:0018108 72 0.015
olfactory behavior GO:0042048 2 0.015

Tp53 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
nervous system disease DOID:863 0 0.030
musculoskeletal system disease DOID:17 0 0.024
large intestine cancer DOID:5672 0 0.015
Human
colon cancer DOID:219 0 0.015
Human
gastrointestinal system cancer DOID:3119 0 0.015
Human
intestinal cancer DOID:10155 0 0.015
Human
cancer DOID:162 0 0.015
Human
disease of cellular proliferation DOID:14566 0 0.015
Human
organ system cancer DOID:0050686 0 0.015
Human
colorectal cancer DOID:9256 0 0.015
Human