Rattus norvegicus

101 known processes

Guca1a

guanylate cyclase activator 1a (retina)

Guca1a biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to extracellular stimulus GO:0009991 380 0.205
intracellular signal transduction GO:0035556 314 0.202
transmembrane transport GO:0055085 412 0.189
regulation of phosphorus metabolic process GO:0051174 349 0.134
regulation of hormone levels GO:0010817 187 0.112
macromolecule localization GO:0033036 252 0.086
regulation of cellular protein metabolic process GO:0032268 267 0.085
macromolecular complex subunit organization GO:0043933 339 0.084
regulation of molecular function GO:0065009 398 0.082
response to nutrient levels GO:0031667 370 0.077
regulation of cellular localization GO:0060341 263 0.073
response to biotic stimulus GO:0009607 226 0.073
response to external biotic stimulus GO:0043207 221 0.071
apoptotic process GO:0006915 381 0.071
cellular response to stress GO:0033554 269 0.071
programmed cell death GO:0012501 392 0.068
organelle organization GO:0006996 266 0.066
response to other organism GO:0051707 220 0.066
purine nucleotide metabolic process GO:0006163 229 0.065
anion transport GO:0006820 178 0.060
ribonucleotide metabolic process GO:0009259 231 0.058
protein phosphorylation GO:0006468 345 0.057
regulation of protein modification process GO:0031399 194 0.056
positive regulation of phosphorus metabolic process GO:0010562 262 0.056
hormone transport GO:0009914 121 0.056
regulation of phosphorylation GO:0042325 248 0.056
cellular ketone metabolic process GO:0042180 51 0.055
protein complex subunit organization GO:0071822 302 0.054
response to estrogen GO:0043627 232 0.054
response to peptide GO:1901652 292 0.054
regulation of protein metabolic process GO:0051246 289 0.053
positive regulation of transport GO:0051050 245 0.053
response to glucocorticoid GO:0051384 223 0.052
regulation of programmed cell death GO:0043067 341 0.052
dna metabolic process GO:0006259 96 0.052
purine containing compound metabolic process GO:0072521 253 0.052
transcription dna templated GO:0006351 377 0.050
negative regulation of metabolic process GO:0009892 331 0.050
macromolecular complex assembly GO:0065003 273 0.050
protein complex biogenesis GO:0070271 263 0.049
regulation of cellular ketone metabolic process GO:0010565 27 0.049
regulation of secretion GO:0051046 224 0.049
action potential GO:0001508 54 0.047
response to inorganic substance GO:0010035 377 0.046
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.046
nitrogen compound transport GO:0071705 229 0.046
negative regulation of apoptotic process GO:0043066 181 0.045
regulation of apoptotic process GO:0042981 335 0.045
amine metabolic process GO:0009308 38 0.045
carbohydrate derivative metabolic process GO:1901135 346 0.044
regulation of catalytic activity GO:0050790 304 0.044
cell cycle GO:0007049 101 0.044
reproductive process GO:0022414 372 0.043
regulation of multicellular organismal development GO:2000026 376 0.043
single organism organelle organization GO:1902589 180 0.042
cation transport GO:0006812 382 0.042
cellular response to corticosteroid stimulus GO:0071384 69 0.042
response to wounding GO:0009611 254 0.041
rna metabolic process GO:0016070 406 0.041
regulation of neurogenesis GO:0050767 247 0.041
regulation of secretion by cell GO:1903530 208 0.041
regulation of cell proliferation GO:0042127 359 0.040
positive regulation of molecular function GO:0044093 230 0.040
regulation of intracellular signal transduction GO:1902531 218 0.039
negative regulation of signaling GO:0023057 157 0.039
response to molecule of bacterial origin GO:0002237 194 0.038
oxoacid metabolic process GO:0043436 290 0.038
response to corticosteroid GO:0031960 235 0.037
response to carbohydrate GO:0009743 183 0.037
response to growth factor GO:0070848 189 0.037
response to peptide hormone GO:0043434 278 0.036
regulation of phosphate metabolic process GO:0019220 349 0.036
regulation of kinase activity GO:0043549 117 0.036
aging GO:0007568 241 0.035
cellular chemical homeostasis GO:0055082 247 0.034
regulation of transferase activity GO:0051338 123 0.034
response to lipopolysaccharide GO:0032496 191 0.034
regulation of system process GO:0044057 208 0.034
single organism biosynthetic process GO:0044711 342 0.034
catabolic process GO:0009056 351 0.033
mapk cascade GO:0000165 140 0.033
cellular response to ketone GO:1901655 51 0.033
cellular component assembly GO:0022607 360 0.033
reproduction GO:0000003 245 0.033
regulation of cellular component organization GO:0051128 368 0.033
organic acid metabolic process GO:0006082 292 0.033
response to nutrient GO:0007584 248 0.032
hormone metabolic process GO:0042445 69 0.032
regulation of protein phosphorylation GO:0001932 183 0.032
neurological system process GO:0050877 219 0.031
muscle system process GO:0003012 115 0.030
response to acid chemical GO:0001101 222 0.030
protein complex assembly GO:0006461 263 0.030
response to transition metal nanoparticle GO:1990267 122 0.030
cellular amine metabolic process GO:0044106 38 0.030
reproductive system development GO:0061458 128 0.030
organonitrogen compound biosynthetic process GO:1901566 167 0.029
positive regulation of protein modification process GO:0031401 142 0.029
peptide transport GO:0015833 97 0.029
cellular catabolic process GO:0044248 295 0.029
cellular homeostasis GO:0019725 252 0.028
positive regulation of peptide hormone secretion GO:0090277 50 0.028
protein localization GO:0008104 191 0.028
negative regulation of molecular function GO:0044092 133 0.028
response to organophosphorus GO:0046683 102 0.028
multi organism reproductive process GO:0044703 262 0.027
positive regulation of cellular biosynthetic process GO:0031328 295 0.027
response to dexamethasone GO:0071548 49 0.027
proteolysis GO:0006508 175 0.027
cellular response to hormone stimulus GO:0032870 247 0.026
male sex differentiation GO:0046661 64 0.026
cellular response to lipid GO:0071396 201 0.026
ion transmembrane transport GO:0034220 365 0.026
negative regulation of cellular metabolic process GO:0031324 281 0.026
positive regulation of secretion GO:0051047 140 0.026
positive regulation of hormone secretion GO:0046887 65 0.026
response to metal ion GO:0010038 253 0.026
carbohydrate derivative biosynthetic process GO:1901137 124 0.025
regulation of cyclic nucleotide metabolic process GO:0030799 51 0.025
regulation of protein kinase activity GO:0045859 105 0.025
multicellular organismal reproductive process GO:0048609 233 0.025
cellular response to growth factor stimulus GO:0071363 162 0.025
cellular response to oxygen containing compound GO:1901701 386 0.025
neuron differentiation GO:0030182 368 0.024
positive regulation of cellular protein metabolic process GO:0032270 167 0.024
nucleotide metabolic process GO:0009117 279 0.024
single organism behavior GO:0044708 130 0.024
negative regulation of cell death GO:0060548 229 0.024
single organism reproductive process GO:0044702 297 0.024
purine nucleoside monophosphate metabolic process GO:0009126 84 0.024
carboxylic acid metabolic process GO:0019752 289 0.024
cellular protein localization GO:0034613 122 0.023
multicellular organism reproduction GO:0032504 233 0.023
response to toxic substance GO:0009636 133 0.023
muscle contraction GO:0006936 88 0.023
negative regulation of macromolecule metabolic process GO:0010605 260 0.023
regulation of cell development GO:0060284 263 0.023
blood circulation GO:0008015 183 0.023
positive regulation of signaling GO:0023056 270 0.023
neural crest cell development GO:0014032 2 0.023
single organism catabolic process GO:0044712 283 0.023
developmental process involved in reproduction GO:0003006 159 0.022
central nervous system development GO:0007417 311 0.022
cellular response to organic cyclic compound GO:0071407 202 0.022
cellular component biogenesis GO:0044085 368 0.022
regulation of peptide transport GO:0090087 87 0.022
cell activation GO:0001775 97 0.022
cyclic purine nucleotide metabolic process GO:0052652 62 0.022
cellular response to steroid hormone stimulus GO:0071383 93 0.022
secretion GO:0046903 307 0.022
learning or memory GO:0007611 90 0.022
gonad development GO:0008406 104 0.021
regulation of nucleic acid templated transcription GO:1903506 380 0.021
organophosphate metabolic process GO:0019637 370 0.021
cellular amino acid metabolic process GO:0006520 107 0.021
negative regulation of gene expression GO:0010629 199 0.021
response to electrical stimulus GO:0051602 56 0.021
positive regulation of cell communication GO:0010647 271 0.021
positive regulation of multicellular organismal process GO:0051240 387 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.020
cell cycle process GO:0022402 57 0.020
positive regulation of developmental process GO:0051094 283 0.020
rhythmic process GO:0048511 156 0.020
organic hydroxy compound metabolic process GO:1901615 115 0.020
positive regulation of catalytic activity GO:0043085 184 0.020
cellular hormone metabolic process GO:0034754 49 0.020
negative regulation of cell differentiation GO:0045596 99 0.020
negative regulation of cellular protein metabolic process GO:0032269 106 0.019
positive regulation of cell proliferation GO:0008284 249 0.019
positive regulation of phosphorylation GO:0042327 177 0.019
response to radiation GO:0009314 137 0.019
regulation of signal transduction GO:0009966 318 0.019
ossification GO:0001503 70 0.019
response to temperature stimulus GO:0009266 94 0.019
negative regulation of protein metabolic process GO:0051248 114 0.019
regulation of tube size GO:0035150 89 0.018
regulation of cellular amino acid metabolic process GO:0006521 2 0.018
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.018
vesicle mediated transport GO:0016192 181 0.018
negative regulation of catalytic activity GO:0043086 103 0.018
regulation of transmembrane transport GO:0034762 122 0.018
cellular response to glucocorticoid stimulus GO:0071385 68 0.018
head development GO:0060322 247 0.018
secretion by cell GO:0032940 248 0.018
negative regulation of multicellular organismal process GO:0051241 203 0.018
cell projection organization GO:0030030 302 0.018
protein transport GO:0015031 132 0.018
regulation of blood circulation GO:1903522 110 0.018
gamete generation GO:0007276 124 0.018
neuron projection development GO:0031175 273 0.018
homeostatic process GO:0042592 331 0.017
male gonad development GO:0008584 59 0.017
aromatic compound catabolic process GO:0019439 168 0.017
regulation of cellular amine metabolic process GO:0033238 8 0.017
nucleoside phosphate biosynthetic process GO:1901293 102 0.017
signal transduction by phosphorylation GO:0023014 144 0.017
positive regulation of leukocyte activation GO:0002696 30 0.017
response to glucose GO:0009749 136 0.017
organic acid transport GO:0015849 116 0.017
positive regulation of protein phosphorylation GO:0001934 135 0.017
tissue development GO:0009888 252 0.017
development of primary sexual characteristics GO:0045137 107 0.017
hormone secretion GO:0046879 115 0.017
neurotransmitter uptake GO:0001504 3 0.016
cardiovascular system development GO:0072358 134 0.016
positive regulation of protein kinase activity GO:0045860 73 0.016
behavior GO:0007610 205 0.016
glutathione transport GO:0034635 2 0.016
negative regulation of neuron differentiation GO:0045665 62 0.016
cell cell signaling GO:0007267 335 0.016
purine nucleoside triphosphate metabolic process GO:0009144 141 0.016
epithelial cell differentiation GO:0030855 71 0.016
amide transport GO:0042886 105 0.016
establishment of protein localization GO:0045184 141 0.016
negative regulation of signal transduction GO:0009968 83 0.016
organic substance catabolic process GO:1901575 316 0.016
negative regulation of biosynthetic process GO:0009890 168 0.016
response to cytokine GO:0034097 215 0.016
regulation of peptide secretion GO:0002791 82 0.016
positive regulation of biosynthetic process GO:0009891 319 0.016
neuron development GO:0048666 286 0.016
male gamete generation GO:0048232 99 0.016
response to camp GO:0051591 91 0.015
intracellular transport GO:0046907 185 0.015
positive regulation of rna metabolic process GO:0051254 203 0.015
regulation of immune system process GO:0002682 123 0.015
amine transport GO:0015837 57 0.015
cellular response to endogenous stimulus GO:0071495 377 0.015
salivary gland development GO:0007431 3 0.015
positive regulation of transferase activity GO:0051347 81 0.015
regulation of mapk cascade GO:0043408 116 0.015
renal system process GO:0003014 40 0.015
spermatogenesis GO:0007283 99 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.015
positive regulation of humoral immune response GO:0002922 2 0.015
regulation of transcription dna templated GO:0006355 374 0.015
lipid metabolic process GO:0006629 283 0.015
cell morphogenesis GO:0000902 142 0.015
cyclic nucleotide metabolic process GO:0009187 80 0.015
regulation of muscle system process GO:0090257 79 0.015
multi multicellular organism process GO:0044706 138 0.015
regulation of metal ion transport GO:0010959 118 0.014
response to estradiol GO:0032355 164 0.014
positive regulation of cell development GO:0010720 176 0.014
regulation of cell cycle GO:0051726 73 0.014
positive regulation of phosphate metabolic process GO:0045937 262 0.014
monocarboxylic acid transport GO:0015718 52 0.014
divalent inorganic cation transport GO:0072511 134 0.014
response to calcium ion GO:0051592 59 0.014
sulfur compound transport GO:0072348 8 0.014
regulation of homeostatic process GO:0032844 101 0.014
alcohol metabolic process GO:0006066 77 0.014
ribonucleoside monophosphate metabolic process GO:0009161 88 0.014
eye morphogenesis GO:0048592 4 0.014
neuron death GO:0070997 127 0.014
response to ketone GO:1901654 182 0.014
positive regulation of cellular amine metabolic process GO:0033240 3 0.014
signal release GO:0023061 145 0.014
calcium ion transport GO:0006816 131 0.014
regulation of nervous system development GO:0051960 264 0.014
protein homooligomerization GO:0051260 91 0.014
negative regulation of phosphate metabolic process GO:0045936 80 0.014
negative regulation of cell communication GO:0010648 158 0.014
ribose phosphate metabolic process GO:0019693 235 0.014
positive regulation of cellular component organization GO:0051130 200 0.014
actin filament based process GO:0030029 86 0.014
actin filament organization GO:0007015 42 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.014
regulation of calcium ion transport GO:0051924 77 0.013
organ morphogenesis GO:0009887 75 0.013
purine nucleoside metabolic process GO:0042278 169 0.013
negative regulation of programmed cell death GO:0043069 183 0.013
regulation of anatomical structure size GO:0090066 135 0.013
sex differentiation GO:0007548 113 0.013
response to hypoxia GO:0001666 231 0.013
response to mechanical stimulus GO:0009612 134 0.013
antral ovarian follicle growth GO:0001547 3 0.013
nucleobase containing small molecule metabolic process GO:0055086 316 0.013
cellular metal ion homeostasis GO:0006875 172 0.013
carbohydrate derivative catabolic process GO:1901136 147 0.013
organic anion transport GO:0015711 132 0.013
protein oligomerization GO:0051259 191 0.013
purine ribonucleoside monophosphate metabolic process GO:0009167 84 0.013
purine containing compound biosynthetic process GO:0072522 85 0.013
chemokine metabolic process GO:0050755 3 0.013
nucleoside phosphate metabolic process GO:0006753 283 0.013
regulation of cell differentiation GO:0045595 320 0.013
intracellular protein transport GO:0006886 79 0.013
response to vitamin GO:0033273 131 0.013
heart morphogenesis GO:0003007 3 0.013
organonitrogen compound catabolic process GO:1901565 179 0.013
cation transmembrane transport GO:0098655 263 0.013
nucleic acid templated transcription GO:0097659 379 0.012
regulation of lipid metabolic process GO:0019216 68 0.012
cellular nitrogen compound catabolic process GO:0044270 163 0.012
cellular macromolecule localization GO:0070727 122 0.012
divalent metal ion transport GO:0070838 132 0.012
negative regulation of rna metabolic process GO:0051253 123 0.012
positive regulation of response to stimulus GO:0048584 285 0.012
regulation of neuron differentiation GO:0045664 208 0.012
positive regulation of protein kinase b signaling GO:0051897 10 0.012
response to oxidative stress GO:0006979 186 0.012
cytoskeleton organization GO:0007010 111 0.012
metal ion transport GO:0030001 289 0.012
glycosyl compound catabolic process GO:1901658 126 0.012
organic cyclic compound catabolic process GO:1901361 175 0.012
rna biosynthetic process GO:0032774 380 0.012
ribose phosphate biosynthetic process GO:0046390 87 0.012
vascular process in circulatory system GO:0003018 96 0.012
divalent inorganic cation homeostasis GO:0072507 165 0.012
steroid metabolic process GO:0008202 73 0.012
negative regulation of rna biosynthetic process GO:1902679 118 0.012
anatomical structure morphogenesis GO:0009653 298 0.012
response to bacterium GO:0009617 200 0.012
choline transport GO:0015871 4 0.012
coronary vasculature morphogenesis GO:0060977 3 0.012
vasoconstriction GO:0042310 54 0.012
regulation of organelle organization GO:0033043 80 0.012
cognition GO:0050890 92 0.012
calcium ion transmembrane transport GO:0070588 70 0.012
positive regulation of nucleic acid templated transcription GO:1903508 197 0.012
purine ribonucleoside metabolic process GO:0046128 168 0.012
purine nucleotide biosynthetic process GO:0006164 83 0.011
development of primary male sexual characteristics GO:0046546 59 0.011
positive regulation of dna metabolic process GO:0051054 39 0.011
amino acid transport GO:0006865 70 0.011
gastrulation GO:0007369 2 0.011
lens fiber cell differentiation GO:0070306 3 0.011
response to alkaloid GO:0043279 132 0.011
acid secretion GO:0046717 48 0.011
cellular ion homeostasis GO:0006873 184 0.011
positive regulation of protein metabolic process GO:0051247 178 0.011
circulatory system process GO:0003013 183 0.011
carboxylic acid transport GO:0046942 115 0.011
negative regulation of cellular biosynthetic process GO:0031327 161 0.011
response to monosaccharide GO:0034284 159 0.011
lymphocyte proliferation GO:0046651 29 0.011
positive regulation of kinase activity GO:0033674 77 0.011
carbohydrate biosynthetic process GO:0016051 42 0.011
positive regulation of secretion by cell GO:1903532 128 0.011
regulation of ion transport GO:0043269 245 0.011
regulation of peptide hormone secretion GO:0090276 80 0.011
cell type specific apoptotic process GO:0097285 134 0.011
carbohydrate metabolic process GO:0005975 130 0.011
nucleobase containing compound catabolic process GO:0034655 152 0.011
muscle tissue development GO:0060537 58 0.011
positive regulation of cell differentiation GO:0045597 217 0.011
regulation of saliva secretion GO:0046877 3 0.011
positive regulation of peptide secretion GO:0002793 52 0.011
glucose homeostasis GO:0042593 75 0.011
mitotic cell cycle GO:0000278 49 0.011
ribonucleoside metabolic process GO:0009119 174 0.011
cytoplasmic transport GO:0016482 115 0.011
regulation of cytoskeleton organization GO:0051493 49 0.011
organic hydroxy compound transport GO:0015850 77 0.011
chemical homeostasis GO:0048878 292 0.011
regulation of hydrolase activity GO:0051336 143 0.011
regulation of dna metabolic process GO:0051052 60 0.011
cellular response to alcohol GO:0097306 87 0.011
dna replication GO:0006260 37 0.010
positive regulation of cell death GO:0010942 184 0.010
response to purine containing compound GO:0014074 126 0.010
neural crest cell migration GO:0001755 1 0.010
cell cycle checkpoint GO:0000075 2 0.010
glycosyl compound metabolic process GO:1901657 182 0.010
purine ribonucleotide catabolic process GO:0009154 136 0.010
negative regulation of transport GO:0051051 136 0.010
negative regulation of nucleic acid templated transcription GO:1903507 117 0.010
sexual reproduction GO:0019953 148 0.010
positive regulation of neurogenesis GO:0050769 165 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.010
cellular macromolecular complex assembly GO:0034622 58 0.010
peptide secretion GO:0002790 86 0.010
fertilization GO:0009566 3 0.010
g protein coupled receptor internalization GO:0002031 3 0.010

Guca1a disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 0 0.245
Human
disease of anatomical entity DOID:7 0 0.245
Human
nervous system disease DOID:863 0 0.245
Human
retinal disease DOID:5679 0 0.222
Human
night blindness DOID:8499 0 0.222
eye and adnexa disease DOID:1492 0 0.222
Human
eye disease DOID:5614 0 0.222
Human
retinal degeneration DOID:8466 0 0.030
Human
retinitis pigmentosa DOID:10584 0 0.030
myopathy DOID:423 0 0.030
muscular disease DOID:0080000 0 0.030
musculoskeletal system disease DOID:17 0 0.030
muscle tissue disease DOID:66 0 0.030