Rattus norvegicus

0 known processes

Tmem2

transmembrane protein 2

Tmem2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna metabolic process GO:0016070 406 0.084
transcription dna templated GO:0006351 377 0.068
programmed cell death GO:0012501 392 0.067
apoptotic process GO:0006915 381 0.065
positive regulation of response to stimulus GO:0048584 285 0.064
regulation of rna biosynthetic process GO:2001141 381 0.061
transmembrane transport GO:0055085 412 0.058
locomotion GO:0040011 237 0.058
regulation of programmed cell death GO:0043067 341 0.058
cellular component movement GO:0006928 248 0.057
regulation of rna metabolic process GO:0051252 391 0.051
cation transport GO:0006812 382 0.051
rna biosynthetic process GO:0032774 380 0.051
regulation of apoptotic process GO:0042981 335 0.051
anatomical structure morphogenesis GO:0009653 298 0.046
nucleotide metabolic process GO:0009117 279 0.046
positive regulation of cell death GO:0010942 184 0.046
organic substance catabolic process GO:1901575 316 0.045
nucleic acid templated transcription GO:0097659 379 0.045
cell migration GO:0016477 197 0.045
regulation of signal transduction GO:0009966 318 0.044
cell cell signaling GO:0007267 335 0.043
carbohydrate derivative metabolic process GO:1901135 346 0.042
oxoacid metabolic process GO:0043436 290 0.041
metal ion transport GO:0030001 289 0.041
regulation of protein metabolic process GO:0051246 289 0.040
nucleobase containing small molecule metabolic process GO:0055086 316 0.040
carboxylic acid metabolic process GO:0019752 289 0.039
macromolecular complex subunit organization GO:0043933 339 0.039
negative regulation of metabolic process GO:0009892 331 0.038
ion transmembrane transport GO:0034220 365 0.038
chemical homeostasis GO:0048878 292 0.038
positive regulation of multicellular organismal process GO:0051240 387 0.038
neuron differentiation GO:0030182 368 0.037
cell motility GO:0048870 202 0.037
regulation of molecular function GO:0065009 398 0.037
response to extracellular stimulus GO:0009991 380 0.036
negative regulation of macromolecule metabolic process GO:0010605 260 0.035
cellular component biogenesis GO:0044085 368 0.035
negative regulation of cell death GO:0060548 229 0.035
homeostatic process GO:0042592 331 0.034
response to inorganic substance GO:0010035 377 0.034
defense response GO:0006952 194 0.034
single organism biosynthetic process GO:0044711 342 0.034
positive regulation of nitrogen compound metabolic process GO:0051173 334 0.034
response to nutrient levels GO:0031667 370 0.034
negative regulation of nitrogen compound metabolic process GO:0051172 161 0.034
negative regulation of cellular metabolic process GO:0031324 281 0.034
catabolic process GO:0009056 351 0.034
negative regulation of cellular biosynthetic process GO:0031327 161 0.033
organic acid metabolic process GO:0006082 292 0.033
intracellular signal transduction GO:0035556 314 0.033
protein complex assembly GO:0006461 263 0.032
cellular component assembly GO:0022607 360 0.032
cellular response to stress GO:0033554 269 0.032
regulation of cellular protein metabolic process GO:0032268 267 0.032
organophosphate metabolic process GO:0019637 370 0.032
anion transport GO:0006820 178 0.031
cellular response to lipid GO:0071396 201 0.031
amine metabolic process GO:0009308 38 0.031
reproductive process GO:0022414 372 0.031
positive regulation of signaling GO:0023056 270 0.031
positive regulation of cell communication GO:0010647 271 0.031
regulation of cellular component organization GO:0051128 368 0.031
regulation of transcription dna templated GO:0006355 374 0.030
regulation of nucleic acid templated transcription GO:1903506 380 0.030
regulation of response to stress GO:0080134 126 0.030
purine containing compound metabolic process GO:0072521 253 0.030
negative regulation of programmed cell death GO:0043069 183 0.029
cellular response to endogenous stimulus GO:0071495 377 0.029
metal ion homeostasis GO:0055065 186 0.029
macromolecular complex assembly GO:0065003 273 0.029
negative regulation of apoptotic process GO:0043066 181 0.028
central nervous system development GO:0007417 311 0.028
nucleoside phosphate metabolic process GO:0006753 283 0.028
protein complex subunit organization GO:0071822 302 0.028
response to metal ion GO:0010038 253 0.028
cation homeostasis GO:0055080 195 0.028
ribonucleoside metabolic process GO:0009119 174 0.027
positive regulation of intracellular signal transduction GO:1902533 138 0.027
positive regulation of phosphate metabolic process GO:0045937 262 0.027
cation transmembrane transport GO:0098655 263 0.027
regulation of cell differentiation GO:0045595 320 0.027
response to cytokine GO:0034097 215 0.027
organelle organization GO:0006996 266 0.027
divalent inorganic cation homeostasis GO:0072507 165 0.027
protein complex biogenesis GO:0070271 263 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 319 0.026
head development GO:0060322 247 0.026
localization of cell GO:0051674 202 0.026
regulation of phosphate metabolic process GO:0019220 349 0.026
negative regulation of rna metabolic process GO:0051253 123 0.026
nitrogen compound transport GO:0071705 229 0.026
protein localization GO:0008104 191 0.026
ribonucleotide metabolic process GO:0009259 231 0.026
brain development GO:0007420 247 0.025
regulation of multicellular organismal development GO:2000026 376 0.025
secretion GO:0046903 307 0.025
regulation of intracellular signal transduction GO:1902531 218 0.025
positive regulation of transport GO:0051050 245 0.025
response to decreased oxygen levels GO:0036293 237 0.025
purine ribonucleotide metabolic process GO:0009150 227 0.025
cellular amino acid metabolic process GO:0006520 107 0.025
cellular response to oxygen containing compound GO:1901701 386 0.024
positive regulation of biosynthetic process GO:0009891 319 0.024
neuron development GO:0048666 286 0.024
response to molecule of bacterial origin GO:0002237 194 0.024
macromolecule localization GO:0033036 252 0.024
secretion by cell GO:0032940 248 0.024
ion homeostasis GO:0050801 212 0.024
nucleoside triphosphate metabolic process GO:0009141 144 0.024
response to estrogen GO:0043627 232 0.024
purine nucleotide metabolic process GO:0006163 229 0.024
regulation of cell development GO:0060284 263 0.024
regulation of phosphorus metabolic process GO:0051174 349 0.024
reproduction GO:0000003 245 0.024
regulation of ion transport GO:0043269 245 0.024
positive regulation of programmed cell death GO:0043068 157 0.024
cellular amine metabolic process GO:0044106 38 0.024
positive regulation of phosphorus metabolic process GO:0010562 262 0.024
cellular chemical homeostasis GO:0055082 247 0.024
protein phosphorylation GO:0006468 345 0.024
lipid metabolic process GO:0006629 283 0.023
positive regulation of developmental process GO:0051094 283 0.023
regulation of locomotion GO:0040012 148 0.023
response to ketone GO:1901654 182 0.022
single organism catabolic process GO:0044712 283 0.022
response to biotic stimulus GO:0009607 226 0.022
organonitrogen compound biosynthetic process GO:1901566 167 0.022
regulation of nervous system development GO:0051960 264 0.022
cellular response to hormone stimulus GO:0032870 247 0.022
response to nutrient GO:0007584 248 0.022
regulation of catalytic activity GO:0050790 304 0.022
cellular calcium ion homeostasis GO:0006874 160 0.022
inorganic cation transmembrane transport GO:0098662 202 0.022
negative regulation of nucleic acid templated transcription GO:1903507 117 0.022
vesicle mediated transport GO:0016192 181 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 148 0.021
inorganic ion transmembrane transport GO:0098660 229 0.021
response to lipopolysaccharide GO:0032496 191 0.021
cell projection organization GO:0030030 302 0.021
cellular catabolic process GO:0044248 295 0.021
response to other organism GO:0051707 220 0.021
negative regulation of biosynthetic process GO:0009890 168 0.021
response to peptide GO:1901652 292 0.021
negative regulation of cellular macromolecule biosynthetic process GO:2000113 141 0.021
neuron projection development GO:0031175 273 0.021
positive regulation of protein metabolic process GO:0051247 178 0.021
positive regulation of cell proliferation GO:0008284 249 0.021
positive regulation of apoptotic process GO:0043065 154 0.021
aging GO:0007568 241 0.021
positive regulation of cellular component organization GO:0051130 200 0.021
cellular response to cytokine stimulus GO:0071345 127 0.021
cellular homeostasis GO:0019725 252 0.021
protein oligomerization GO:0051259 191 0.021
response to oxidative stress GO:0006979 186 0.021
proteolysis GO:0006508 175 0.020
multicellular organismal reproductive process GO:0048609 233 0.020
nucleoside metabolic process GO:0009116 179 0.020
negative regulation of molecular function GO:0044092 133 0.020
regulation of cellular amine metabolic process GO:0033238 8 0.020
response to growth factor GO:0070848 189 0.020
regulation of cellular amino acid metabolic process GO:0006521 2 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 247 0.019
regulation of cell proliferation GO:0042127 359 0.019
regulation of cellular localization GO:0060341 263 0.019
positive regulation of cellular protein metabolic process GO:0032270 167 0.019
positive regulation of molecular function GO:0044093 230 0.019
response to oxygen levels GO:0070482 265 0.019
carbohydrate derivative biosynthetic process GO:1901137 124 0.019
tissue development GO:0009888 252 0.019
negative regulation of gene expression GO:0010629 199 0.019
regulation of phosphorylation GO:0042325 248 0.019
regulation of cellular ketone metabolic process GO:0010565 27 0.019
calcium ion homeostasis GO:0055074 162 0.019
regulation of cellular component movement GO:0051270 150 0.019
positive regulation of signal transduction GO:0009967 175 0.019
positive regulation of cell differentiation GO:0045597 217 0.018
response to radiation GO:0009314 137 0.018
multicellular organism growth GO:0035264 1 0.018
purine nucleoside metabolic process GO:0042278 169 0.018
multicellular organism reproduction GO:0032504 233 0.018
regulation of membrane potential GO:0042391 110 0.018
organophosphate biosynthetic process GO:0090407 143 0.018
synaptic transmission GO:0007268 235 0.018
regulation of hormone levels GO:0010817 187 0.018
response to bacterium GO:0009617 200 0.018
cellular metal ion homeostasis GO:0006875 172 0.018
cellular divalent inorganic cation homeostasis GO:0072503 162 0.018
immune system process GO:0002376 204 0.018
purine nucleoside triphosphate metabolic process GO:0009144 141 0.017
ribose phosphate metabolic process GO:0019693 235 0.017
cellular ketone metabolic process GO:0042180 51 0.017
cellular component morphogenesis GO:0032989 155 0.017
response to corticosteroid GO:0031960 235 0.017
transcription from rna polymerase ii promoter GO:0006366 252 0.017
cellular ion homeostasis GO:0006873 184 0.017
positive regulation of gene expression GO:0010628 244 0.017
mapk cascade GO:0000165 140 0.017
regulation of neurogenesis GO:0050767 247 0.017
multi organism reproductive process GO:0044703 262 0.017
ras protein signal transduction GO:0007265 29 0.017
purine nucleotide catabolic process GO:0006195 136 0.017
response to vitamin GO:0033273 131 0.017
cytosolic calcium ion homeostasis GO:0051480 140 0.017
purine ribonucleoside metabolic process GO:0046128 168 0.017
negative regulation of rna biosynthetic process GO:1902679 118 0.017
intracellular transport GO:0046907 185 0.017
single organism reproductive process GO:0044702 297 0.017
regulation of cell motility GO:2000145 131 0.017
negative regulation of response to stimulus GO:0048585 155 0.017
organic anion transport GO:0015711 132 0.016
carboxylic acid transport GO:0046942 115 0.016
positive regulation of cell development GO:0010720 176 0.016
glycosyl compound metabolic process GO:1901657 182 0.016
positive regulation of catalytic activity GO:0043085 184 0.016
inflammatory response GO:0006954 150 0.016
small gtpase mediated signal transduction GO:0007264 36 0.016
response to hypoxia GO:0001666 231 0.016
regulation of protein modification process GO:0031399 194 0.016
positive regulation of cellular biosynthetic process GO:0031328 295 0.016
cardiovascular system development GO:0072358 134 0.016
monovalent inorganic cation transport GO:0015672 172 0.016
heterocycle catabolic process GO:0046700 167 0.016
nucleoside catabolic process GO:0009164 126 0.016
negative regulation of signaling GO:0023057 157 0.016
divalent metal ion transport GO:0070838 132 0.016
regulation of neuron projection development GO:0010975 161 0.016
cell morphogenesis GO:0000902 142 0.015
cellular macromolecule localization GO:0070727 122 0.015
regulation of transcription from rna polymerase ii promoter GO:0006357 234 0.015
response to glucocorticoid GO:0051384 223 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 85 0.015
hormone secretion GO:0046879 115 0.015
gastrulation GO:0007369 2 0.015
positive regulation of cell motility GO:2000147 97 0.015
cellular cation homeostasis GO:0030003 180 0.015
negative regulation of transcription dna templated GO:0045892 116 0.015
developmental process involved in reproduction GO:0003006 159 0.015
response to acid chemical GO:0001101 222 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 153 0.015
negative regulation of cell communication GO:0010648 158 0.015
g protein coupled receptor signaling pathway GO:0007186 242 0.015
response to peptide hormone GO:0043434 278 0.015
response to ethanol GO:0045471 162 0.015
cell morphogenesis involved in differentiation GO:0000904 119 0.015
cell adhesion GO:0007155 110 0.015
taxis GO:0042330 67 0.015
response to mechanical stimulus GO:0009612 134 0.015
signal transduction by phosphorylation GO:0023014 144 0.015
organic acid transport GO:0015849 116 0.015
positive regulation of nucleic acid templated transcription GO:1903508 197 0.015
response to estradiol GO:0032355 164 0.015
positive regulation of phosphorylation GO:0042327 177 0.014
purine ribonucleotide catabolic process GO:0009154 136 0.014
eye morphogenesis GO:0048592 4 0.014
response to external biotic stimulus GO:0043207 221 0.014
alcohol metabolic process GO:0006066 77 0.014
regulation of cell migration GO:0030334 128 0.014
cellular response to molecule of bacterial origin GO:0071219 56 0.014
organic cyclic compound catabolic process GO:1901361 175 0.014
regulation of mapk cascade GO:0043408 116 0.014
reproductive system development GO:0061458 128 0.014
positive regulation of secretion by cell GO:1903532 128 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 122 0.014
regulation of protein phosphorylation GO:0001932 183 0.014
single organism organelle organization GO:1902589 180 0.014
single organism carbohydrate metabolic process GO:0044723 118 0.014
regulation of secretion by cell GO:1903530 208 0.014
nucleotide catabolic process GO:0009166 139 0.014
positive regulation of cell migration GO:0030335 96 0.014
regulation of neuron differentiation GO:0045664 208 0.014
regulation of canonical wnt signaling pathway GO:0060828 4 0.014
organophosphate catabolic process GO:0046434 148 0.014
cytokine production GO:0001816 61 0.014
regulation of cell projection organization GO:0031344 175 0.014
purine ribonucleoside catabolic process GO:0046130 124 0.014
aromatic compound catabolic process GO:0019439 168 0.014
calcium ion transport GO:0006816 131 0.014
nucleobase containing compound catabolic process GO:0034655 152 0.013
negative regulation of innate immune response GO:0045824 4 0.013
heart morphogenesis GO:0003007 3 0.013
positive regulation of rna metabolic process GO:0051254 203 0.013
axis specification GO:0009798 4 0.013
positive regulation of cellular amine metabolic process GO:0033240 3 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 148 0.013
sex differentiation GO:0007548 113 0.013
regulation of purine nucleotide metabolic process GO:1900542 115 0.013
growth GO:0040007 165 0.013
response to reactive oxygen species GO:0000302 120 0.013
cell activation GO:0001775 97 0.013
cellular nitrogen compound catabolic process GO:0044270 163 0.013
establishment of protein localization GO:0045184 141 0.013
muscle system process GO:0003012 115 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 1 0.013
positive regulation of cellular component movement GO:0051272 102 0.013
positive regulation of locomotion GO:0040017 102 0.013
regulation of immune system process GO:0002682 123 0.013
nucleoside triphosphate catabolic process GO:0009143 123 0.013
purine ribonucleoside triphosphate metabolic process GO:0009205 140 0.013
cellular response to growth factor stimulus GO:0071363 162 0.013
purine nucleotide biosynthetic process GO:0006164 83 0.013
lipid biosynthetic process GO:0008610 128 0.013
carbohydrate metabolic process GO:0005975 130 0.013
blood circulation GO:0008015 183 0.013
response to organophosphorus GO:0046683 102 0.013
positive regulation of transcription dna templated GO:0045893 197 0.012
development of primary sexual characteristics GO:0045137 107 0.012
cell type specific apoptotic process GO:0097285 134 0.012
organic hydroxy compound metabolic process GO:1901615 115 0.012
regulation of nucleotide metabolic process GO:0006140 117 0.012
cellular response to organonitrogen compound GO:0071417 197 0.012
response to camp GO:0051591 91 0.012
adult locomotory behavior GO:0008344 4 0.012
response to monosaccharide GO:0034284 159 0.012
biological adhesion GO:0022610 110 0.012
response to hexose GO:0009746 144 0.012
negative regulation of transport GO:0051051 136 0.012
cellular response to external stimulus GO:0071496 118 0.012
response to glucose GO:0009749 136 0.012
divalent inorganic cation transport GO:0072511 134 0.012
response to wounding GO:0009611 254 0.012
dephosphorylation GO:0016311 98 0.012
positive regulation of cytosolic calcium ion concentration GO:0007204 122 0.012
cell projection morphogenesis GO:0048858 123 0.012
single organism intracellular transport GO:1902582 166 0.012
cell part morphogenesis GO:0032990 123 0.012
response to carbohydrate GO:0009743 183 0.012
negative regulation of signal transduction GO:0009968 83 0.012
oxidation reduction process GO:0055114 304 0.012
circulatory system development GO:0072359 134 0.012
organonitrogen compound catabolic process GO:1901565 179 0.012
cellular response to peptide GO:1901653 133 0.012
carbohydrate derivative catabolic process GO:1901136 147 0.012
response to alkaloid GO:0043279 132 0.012
cytoskeleton organization GO:0007010 111 0.012
single organism cellular localization GO:1902580 102 0.012
regulation of growth GO:0040008 105 0.012
neuron death GO:0070997 127 0.012
positive regulation of neurogenesis GO:0050769 165 0.012
behavior GO:0007610 205 0.011
regulation of response to external stimulus GO:0032101 106 0.011
regulation of metal ion transport GO:0010959 118 0.011
gonad development GO:0008406 104 0.011
positive regulation of ion transport GO:0043270 94 0.011
positive regulation of neuron differentiation GO:0045666 126 0.011
positive regulation of mapk cascade GO:0043410 92 0.011
neuron projection morphogenesis GO:0048812 122 0.011
muscle structure development GO:0061061 87 0.011
endocytosis GO:0006897 84 0.011
regulation of vesicle mediated transport GO:0060627 81 0.011
peptide transport GO:0015833 97 0.011
positive regulation of protein modification process GO:0031401 142 0.011
regulation of transmembrane transport GO:0034762 122 0.011
negative regulation of protein metabolic process GO:0051248 114 0.011
regulation of homeostatic process GO:0032844 101 0.011
cellular response to organic cyclic compound GO:0071407 202 0.011
cellular lipid metabolic process GO:0044255 208 0.011
gamete generation GO:0007276 124 0.011
gliogenesis GO:0042063 93 0.011
positive regulation of nervous system development GO:0051962 178 0.011
nucleoside phosphate biosynthetic process GO:1901293 102 0.011
cell cell signaling involved in cell fate commitment GO:0045168 2 0.011
ribonucleotide biosynthetic process GO:0009260 85 0.011
cytoplasmic transport GO:0016482 115 0.011
ribonucleoside catabolic process GO:0042454 126 0.011
rho protein signal transduction GO:0007266 11 0.011
lipid transport GO:0006869 61 0.011
protein homooligomerization GO:0051260 91 0.011
purine nucleoside triphosphate catabolic process GO:0009146 122 0.011
enzyme linked receptor protein signaling pathway GO:0007167 116 0.010
cellular response to biotic stimulus GO:0071216 59 0.010
positive regulation of nucleotide metabolic process GO:0045981 91 0.010
positive regulation of secretion GO:0051047 140 0.010
cellular carbohydrate metabolic process GO:0044262 72 0.010
regulation of system process GO:0044057 208 0.010
positive regulation of catabolic process GO:0009896 78 0.010
cytokine biosynthetic process GO:0042089 3 0.010
protein transport GO:0015031 132 0.010
defense response to gram negative bacterium GO:0050829 3 0.010
negative regulation of cellular protein metabolic process GO:0032269 106 0.010
response to interleukin 1 GO:0070555 55 0.010

Tmem2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in rat and predicted with the rat functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.024
musculoskeletal system disease DOID:17 0 0.017
disease of metabolism DOID:0014667 0 0.015
sensory system disease DOID:0050155 0 0.014
disease of cellular proliferation DOID:14566 0 0.013